pyrazinamide has been researched along with Complications of Diabetes Mellitus in 10 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is a need for individualized dosing of isoniazid and rifampicin based on plasma concentration measurements (therapeutic drug monitoring) and for clinical trials on higher doses of these TB drugs in patients with TB and DM." | 1.51 | Effect of diabetes mellitus on TB drug concentrations in Tanzanian patients. ( Aarnoutse, RE; Boeree, MJ; Burger, DM; Colbers, A; Irongo, CF; Kibiki, GS; Mtabho, CM; Semvua, HH; Tostmann, A; van Crevel, R; van den Boogaard, J; van der Ven, AJAM, 2019) |
| "The currently preferred regimen for treatment of pulmonary tuberculosis (PTB) is isoniazid, rifampin, pyrazinamide, and ethambutol, which has been used either as separate tablets (ST) or as fixed-dose combination (FDC)." | 1.46 | Treatment outcomes of fixed-dose combination versus separate tablet regimens in pulmonary tuberculosis patients with or without diabetes in Qatar. ( Al-Shaer, MH; Elewa, H; Iqbal, F; Mansour, H; Salameh, P, 2017) |
| " In this article, a case series is presented to illustrate the value of individualized TB drug dosing in four patients with low TB drug concentrations." | 1.38 | Therapeutic drug monitoring in the treatment of tuberculosis patients. ( Aarnoutse, R; Boeree, M; Ijdema, D; Magis-Escurra, C; van den Boogaard, J, 2012) |
| "A hundred new cases of active pulmonary tuberculosis whose age was 60 to 87 years were treated by the intensive chemotherapy regimen recommended by the WHO." | 1.32 | [Efficiency of an intensive stage of chemotherapy for tuberculosis in elderly and senile patients]. ( Karachunskiĭ, MA; Uvarova, TE, 2004) |
| "A case of Pulmonary Alveolar Proteinosis (PAP), in association with tuberculosis, is described in a 35-year-old diabetic patient." | 1.31 | Pulmonary alveolar proteinosis and tuberculosis in a diabetic patient: a rare or a seldom diagnosed association? ( Coelho JC, JC; Marinho, MM; Pereira-Silva, JL; Veloso, TV, 2002) |
| "Out of 1128 new pulmonary tuberculosis patients, six-hundred twenty started treatment with six-month (2HRZS or E/4HRE) in Fukujuji Hospital, JATA, in Tokyo from January 1991 to December 1996." | 1.30 | [Six-months chemotherapy (2HRZS or E/4HRE) of new cases of pulmonary tuberculosis--six year experiences on its effectiveness, toxicity, and acceptability]. ( Ito, K; Mizutani, S; Ogata, H; Sugita, H; Wada, M; Yoshiyama, T, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mtabho, CM | 1 |
| Semvua, HH | 1 |
| van den Boogaard, J | 2 |
| Irongo, CF | 1 |
| Boeree, MJ | 1 |
| Colbers, A | 1 |
| Burger, DM | 1 |
| van Crevel, R | 1 |
| van der Ven, AJAM | 1 |
| Kibiki, GS | 1 |
| Tostmann, A | 1 |
| Aarnoutse, RE | 1 |
| Al-Shaer, MH | 1 |
| Mansour, H | 1 |
| Elewa, H | 1 |
| Salameh, P | 1 |
| Iqbal, F | 1 |
| Magis-Escurra, C | 1 |
| Ijdema, D | 1 |
| Boeree, M | 1 |
| Aarnoutse, R | 1 |
| Pereira-Silva, JL | 1 |
| Marinho, MM | 1 |
| Veloso, TV | 1 |
| Coelho JC, JC | 1 |
| Karachunskiĭ, MA | 1 |
| Uvarova, TE | 1 |
| Pilheu, JA | 1 |
| De Salvo, MC | 1 |
| Koch, O | 1 |
| Hiroshige, K | 1 |
| Yuu, K | 1 |
| Takasugi, M | 1 |
| Soejima, M | 1 |
| Kuroiwa, A | 1 |
| Wada, M | 1 |
| Yoshiyama, T | 1 |
| Ogata, H | 1 |
| Ito, K | 1 |
| Mizutani, S | 1 |
| Sugita, H | 1 |
| Onisk, J | 1 |
1 trial available for pyrazinamide and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
[Clinical studies on the ketogenic effect of certain antitubercular drugs in patients with diabetes and pulmonary tuberculosis].
Topics: Adult; Antitubercular Agents; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; E | 1968 |
9 other studies available for pyrazinamide and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Effect of diabetes mellitus on TB drug concentrations in Tanzanian patients.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Diabetes Complications; Diabetes Mellitus; Fe | 2019 |
Treatment outcomes of fixed-dose combination versus separate tablet regimens in pulmonary tuberculosis patients with or without diabetes in Qatar.
Topics: Adult; Antitubercular Agents; Diabetes Complications; Dose-Response Relationship, Drug; Drug Therapy | 2017 |
[Relapse rate of tuberculosis treated with standard regimen of chemotherapy].
Topics: Adolescent; Aged; Aged, 80 and over; Child; Diabetes Complications; Drug Administration Schedule; Fe | 2009 |
Therapeutic drug monitoring in the treatment of tuberculosis patients.
Topics: Adult; Aged; Alcoholism; Antibiotics, Antitubercular; Antitubercular Agents; Chromatography, High Pr | 2012 |
Pulmonary alveolar proteinosis and tuberculosis in a diabetic patient: a rare or a seldom diagnosed association?
Topics: Adult; Diabetes Complications; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Pulmonary Alve | 2002 |
[Efficiency of an intensive stage of chemotherapy for tuberculosis in elderly and senile patients].
Topics: Age Factors; Aged; Aged, 80 and over; Antibiotics, Antitubercular; Antitubercular Agents; Diabetes C | 2004 |
Liver alterations in antituberculosis regimens containing pyrazinamide.
Topics: Adolescent; Adult; Aged; Alcoholism; Antitubercular Agents; Cholestasis; Diabetes Complications; Dia | 1981 |
[A study on uric acid excretion in patients with hypouricemia].
Topics: Acute Kidney Injury; Benzbromarone; Diabetes Complications; Diabetes Mellitus; Female; Humans; Kidne | 1993 |
[Six-months chemotherapy (2HRZS or E/4HRE) of new cases of pulmonary tuberculosis--six year experiences on its effectiveness, toxicity, and acceptability].
Topics: Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Diabetes Complications; Drug T | 1999 |