pyrazinamide has been researched along with Chronic Disease in 32 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rifampin has been reported to cause acute pancreatitis in up to 2." | 1.30 | Pancreatic insufficiency due to antituberculous therapy. ( Cohen, LB; Knowles, SR; Liu, BA; Shear, NH; Werb, MR, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (75.00) | 18.7374 |
| 1990's | 3 (9.38) | 18.2507 |
| 2000's | 4 (12.50) | 29.6817 |
| 2010's | 1 (3.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Opondo, EA | 1 |
| Morais, P | 1 |
| Ferreira, O | 1 |
| Nogueira, A | 1 |
| Bettencourt, H | 1 |
| Azevedo, F | 1 |
| Itoh, Y | 1 |
| Ishiguchi, T | 1 |
| Higashimoto, Y | 1 |
| Fujimoto, H | 1 |
| Ohata, M | 1 |
| Itoh, H | 1 |
| Nishiyama, A | 1 |
| Okamura, K | 1 |
| Ono, H | 1 |
| Kawabe, K | 1 |
| Ueda, A | 1 |
| Suruda, T | 1 |
| Jennings, A | 1 |
| Bilous, M | 1 |
| Asimakis, P | 1 |
| Maloof, AJ | 1 |
| Fujiwara, Y | 1 |
| Takamitsu, Y | 1 |
| Ueda, N | 1 |
| Orita, Y | 1 |
| Abe, H | 1 |
| Barakat, MT | 1 |
| Scott, J | 1 |
| Hughes, JM | 1 |
| Walport, M | 1 |
| Calam, J | 1 |
| Friedland, JS | 1 |
| Ind, PW | 1 |
| McKenna, C | 1 |
| Liu, BA | 1 |
| Knowles, SR | 1 |
| Cohen, LB | 1 |
| Werb, MR | 1 |
| Shear, NH | 1 |
| Choi, IS | 1 |
| Park, JB | 1 |
| Kim, SJ | 1 |
| Joh, JW | 1 |
| Lee, SK | 1 |
| Huh, WS | 1 |
| Oh, HY | 1 |
| Kim, SM | 1 |
| Peck, KR | 1 |
| Song, JH | 1 |
| Kim, MK | 1 |
| Ko, YH | 1 |
| Lee, BB | 1 |
| Kuipers, EJ | 1 |
| Hazenberg, HJ | 1 |
| Ploeger, B | 1 |
| Smit, FW | 1 |
| de Jong, A | 1 |
| Krivinka, R | 1 |
| Tousek, J | 1 |
| Schütz, I | 1 |
| Radenbach, KL | 1 |
| Bartmann, K | 1 |
| Virchow, C | 1 |
| Flemming, J | 1 |
| Rushchak, VA | 1 |
| Stýblo, K | 1 |
| Kubík, A | 1 |
| Langerová, M | 1 |
| Matusková, E | 1 |
| Morávková, K | 1 |
| Jesiotr, M | 1 |
| Bialik, IB | 1 |
| Sirota, DS | 1 |
| Man'kovetskiĭ, EF | 1 |
| Koĭfman, SG | 1 |
| Vatsyk, MZ | 1 |
| Pregowski, W | 1 |
| Stańczuk-Holub, A | 1 |
| Rudoĭ, NM | 1 |
| Utkin, VV | 1 |
| Fedorova, IE | 1 |
| Afanas'eva, IuP | 1 |
| Danovitch, GM | 1 |
| Weinberger, J | 1 |
| Berlyne, GM | 1 |
| Somner, AR | 1 |
| Selkon, JB | 1 |
| Walton, M | 1 |
| White, AB | 1 |
| Susteric, J | 1 |
| Perfeito, JB | 1 |
| Foster-Carter, AF | 1 |
| Lees, AW | 1 |
| Tyrrell, WF | 1 |
| Smith, J | 1 |
| Allan, GW | 1 |
| Böszörményi, M | 2 |
| Fegiz, G | 1 |
| Organick, AB | 1 |
| Wilson, EM | 1 |
| Sighart, H | 1 |
| Opl, G | 1 |
| Zierski, M | 1 |
| Zachara, A | 1 |
| Petera, V | 1 |
| Klapálek, D | 1 |
| Paichl, P | 1 |
| Pecený, A | 1 |
1 trial available for pyrazinamide and Chronic Disease
| Article | Year |
|---|---|
The combination of ethambutol, capreomycin and a third drug in chronic pulmonary tuberculosis with bacterial polyresistance.
Topics: Administration, Oral; Aminosalicylic Acids; Antitubercular Agents; Capreomycin; Chronic Disease; Cli | 1970 |
31 other studies available for pyrazinamide and Chronic Disease
| Article | Year |
|---|---|
Diagnostic challenges of intestinal tuberculosis in a patient with chronic diarrhoea: case report.
Topics: Adult; Antitubercular Agents; Chronic Disease; Diarrhea; Ethambutol; Humans; Isoniazid; Laparotomy; | 2008 |
A nodulo-ulcerative lesion on the nose.
Topics: Aged, 80 and over; Antitubercular Agents; Chronic Disease; Ethambutol; Female; Humans; Isoniazid; Lu | 2010 |
[A case of tuberculosis pleuritis developing contralateral pleural effusion during anti-tuberculosis chemotherapy, falling into chronic respiratory failure].
Topics: Aged; Antitubercular Agents; Chronic Disease; Drug Therapy, Combination; Humans; Isoniazid; Male; Pl | 2002 |
Mycobacterium tuberculosis presenting as chronic red eye.
Topics: Adolescent; Antitubercular Agents; Chronic Disease; Conjunctivitis, Bacterial; Drug Therapy, Combina | 2006 |
Hypouricemia due to an isolated defect in renal tubular urate reabsorption.
Topics: Adult; beta 2-Microglobulin; Chronic Disease; Glomerulonephritis; Humans; Kidney; Male; Phosphates; | 1980 |
Grand rounds--Hammersmith Hospital. Persistent fever in pulmonary tuberculosis.
Topics: Antitubercular Agents; Chronic Disease; Drug Resistance; Fever; Humans; Intestinal Absorption; Isoni | 1996 |
Pancreatic insufficiency due to antituberculous therapy.
Topics: Antitubercular Agents; Chronic Disease; Drug Hypersensitivity; Drug Therapy, Combination; Ethambutol | 1997 |
Tuberculous abscess of the graft in a renal transplant recipient after chronic rejection: case report.
Topics: Abscess; Adult; Antitubercular Agents; Chronic Disease; Drug Therapy, Combination; Ethambutol; Femal | 2000 |
Nontuberculous mycobacterial sternal osteomyelitis in a patient without predisposing condition.
Topics: Adult; Chronic Disease; Drug Therapy, Combination; Female; Fusidic Acid; Humans; Mycobacterium Infec | 1991 |
The first clinical experiences with ethambutol in chronic pulmonary tuberculosis and basilar meningitis.
Topics: Adult; Aminosalicylic Acids; Capreomycin; Chronic Disease; Cycloserine; Drug Combinations; Drug Resi | 1970 |
Clinical results of rifampicin treatment.
Topics: Administration, Oral; Adult; Aged; Capreomycin; Chronic Disease; Drug Combinations; Ethambutol; Fema | 1970 |
[Use of drugs of secondary group in complex therapy of children with chronic tuberculosis].
Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Cycloserine; Ethionamide; Female; Humans; Male | 1971 |
The problem of the chronic excretor of tubercle bacilli.
Topics: Adult; Age Factors; Aged; Aminosalicylic Acids; Chronic Disease; Cycloserine; Czechoslovakia; Drug R | 1968 |
Ethambutol in the treatment of 26 patients with chronic active pulmonary tuberculosis.
Topics: Chronic Disease; Cycloserine; Drug Resistance, Microbial; Ethambutol; Humans; Isoniazid; Kanamycin; | 1969 |
[Kanamycin and florimycin in the clinical course of pulmonary tuberculosis].
Topics: Adolescent; Adult; Albuminuria; Aminosalicylic Acids; Antitubercular Agents; Chronic Disease; Cyclos | 1971 |
[Experience in treatment of patients with chronic destructive pulmonary tuberculosis in a suburban tuberculosis hospital].
Topics: Adult; Antitubercular Agents; Chronic Disease; Cycloserine; Drug Evaluation; Ethambutol; Ethionamide | 1974 |
[Treatment with pyrazinamide given in increased doses twice a week in combination with other drugs].
Topics: Adult; Aged; Antitubercular Agents; Chronic Disease; Drug Hypersensitivity; Drug Synergism; Drug Tol | 1973 |
[Restoration of drug sensitivity in Mycobacterium tuberculosis to streptomycin and isoniazid during treatment with preparations of the 1st series].
Topics: Chronic Disease; Cycloserine; Drug Resistance, Microbial; Ethionamide; Humans; Isoniazid; Mycobacter | 1970 |
Uric acid in advanced renal failure.
Topics: Absorption; Adult; Allopurinol; Biological Transport; Chronic Disease; Glomerular Filtration Rate; H | 1972 |
Drug resistant pulmonary tuberculosis treated with ethambutol and rifampicin in North East England.
Topics: Aminosalicylic Acids; Chronic Disease; Cycloserine; Drug Resistance, Microbial; Ethambutol; Ethionam | 1971 |
The effect of cycloserine in different chemotherapy combinations on chronic pulmonary tuberculosis.
Topics: Chronic Disease; Cycloserine; Ethionamide; Humans; Pyrazinamide; Tuberculosis, Pulmonary | 1970 |
Clinical activity of cycloserine in the treatment of tuberculosis.
Topics: Adult; Aged; Chronic Disease; Cycloserine; Drug Resistance, Microbial; Ethambutol; Female; Humans; M | 1970 |
Chronic tuberculosis in refractory patients--therapeutic aspects.
Topics: Aminosalicylic Acids; Antitubercular Agents; Chronic Disease; Cycloserine; Drug Resistance, Microbia | 1969 |
Ethambutol in the retreatment of chronic pulmonary tuberculosis.
Topics: Aminosalicylic Acids; Chronic Disease; Cycloserine; Depression, Chemical; Drug Synergism; Ethambutol | 1970 |
Report on the therapeutic results obtained with rifampicin.
Topics: Aminosalicylic Acids; Chronic Disease; Drug Combinations; Ethambutol; Humans; Pyrazinamide; Rifampin | 1970 |
Report on experiences with ethambutol.
Topics: Chronic Disease; Cycloserine; Drug Combinations; Ethambutol; Ethionamide; Humans; Phenylthiourea; Py | 1970 |
[Cheotherapy of chronic pulmonary tuberculosis with resistant mycobacteria].
Topics: Aminosalicylic Acids; Antitubercular Agents; Chronic Disease; Cycloserine; Drug Resistance, Microbia | 1967 |
Multiple drugs in retreatment of chronic pulmonary tuberculosis. Results with capreomycin and ethambutol.
Topics: Adult; Aged; Anti-Bacterial Agents; Antitubercular Agents; Chronic Disease; Drug Resistance, Microbi | 1968 |
[Treatment of chronic polyresistant pulmonary tuberculosis using ethionamide, pyrazinamide and cycloserine].
Topics: Adult; Chronic Disease; Cycloserine; Drug Resistance, Microbial; Drug Synergism; Ethionamide; Humans | 1968 |
[Late results of treatment of chronic, cavernous pulmonary tuberculosis with reserve drugs].
Topics: Chronic Disease; Cycloserine; Ethionamide; Humans; Pyrazinamide; Retrospective Studies; Tuberculosis | 1968 |
[On the problem of chronic liver damage following drug therapy of tuberculosis].
Topics: Adult; Aminosalicylic Acids; Antitubercular Agents; Biopsy; Chemical and Drug Induced Liver Injury; | 1965 |