pyrazinamide has been researched along with Chemical Dependence in 4 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Severe liver injuries were attributed to the rifampin and pyrazinamide (RZ) regimen after it was recommended for treating latent tuberculosis infection." | 7.73 | Severe or fatal liver injury in 50 patients in the United States taking rifampin and pyrazinamide for latent tuberculosis infection. ( Bower, WA; Castro, KG; Iademarco, MF; Ijaz, K; Jereb, JA; Lambert, LA; McElroy, PD; Navin, TR; Spradling, PR, 2006) |
| "Severe liver injuries were attributed to the rifampin and pyrazinamide (RZ) regimen after it was recommended for treating latent tuberculosis infection." | 3.73 | Severe or fatal liver injury in 50 patients in the United States taking rifampin and pyrazinamide for latent tuberculosis infection. ( Bower, WA; Castro, KG; Iademarco, MF; Ijaz, K; Jereb, JA; Lambert, LA; McElroy, PD; Navin, TR; Spradling, PR, 2006) |
| " When recommended dosage regiments are followed, the incidence of adverse reactions is low with short-course therapy, and in only 5% or less of patients is it necessary to withdraw one or more drugs." | 2.36 | Short-course therapy for tuberculosis. ( Aquinas, M, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Danna, BJ | 1 |
| Harvey, AW | 1 |
| Woc-Colburn, LE | 1 |
| Ricks, PM | 1 |
| Hershow, RC | 1 |
| Rahimian, A | 1 |
| Huo, D | 1 |
| Johnson, W | 1 |
| Prachand, N | 1 |
| Jimenez, A | 1 |
| Wiebel, W | 1 |
| Paul, W | 1 |
| Ijaz, K | 1 |
| Jereb, JA | 1 |
| Lambert, LA | 1 |
| Bower, WA | 1 |
| Spradling, PR | 1 |
| McElroy, PD | 1 |
| Iademarco, MF | 1 |
| Navin, TR | 1 |
| Castro, KG | 1 |
| Aquinas, M | 1 |
1 review available for pyrazinamide and Chemical Dependence
| Article | Year |
|---|---|
Short-course therapy for tuberculosis.
Topics: Drug Therapy, Combination; Humans; Pyrazinamide; Rifampin; Streptomycin; Substance-Related Disorders | 1982 |
1 trial available for pyrazinamide and Chemical Dependence
| Article | Year |
|---|---|
A randomized trial comparing standard outcomes in two treatment models for substance users with tuberculosis.
Topics: Adult; Antitubercular Agents; Directly Observed Therapy; Drug Users; Ethambutol; Ethnicity; Female; | 2015 |
2 other studies available for pyrazinamide and Chemical Dependence
| Article | Year |
|---|---|
Esophageal Tuberculosis - A Mass of Confusion.
Topics: Aged; Antitubercular Agents; Deglutition Disorders; Delayed Diagnosis; Diagnosis, Differential; Dire | 2020 |
Severe or fatal liver injury in 50 patients in the United States taking rifampin and pyrazinamide for latent tuberculosis infection.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Antitubercular Agents; Chemical and Drug Induced Liver In | 2006 |