pyrazinamide has been researched along with Chemical Dependence in 4 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Excerpt | Relevance | Reference |
---|---|---|
"Severe liver injuries were attributed to the rifampin and pyrazinamide (RZ) regimen after it was recommended for treating latent tuberculosis infection." | 7.73 | Severe or fatal liver injury in 50 patients in the United States taking rifampin and pyrazinamide for latent tuberculosis infection. ( Bower, WA; Castro, KG; Iademarco, MF; Ijaz, K; Jereb, JA; Lambert, LA; McElroy, PD; Navin, TR; Spradling, PR, 2006) |
"Severe liver injuries were attributed to the rifampin and pyrazinamide (RZ) regimen after it was recommended for treating latent tuberculosis infection." | 3.73 | Severe or fatal liver injury in 50 patients in the United States taking rifampin and pyrazinamide for latent tuberculosis infection. ( Bower, WA; Castro, KG; Iademarco, MF; Ijaz, K; Jereb, JA; Lambert, LA; McElroy, PD; Navin, TR; Spradling, PR, 2006) |
" When recommended dosage regiments are followed, the incidence of adverse reactions is low with short-course therapy, and in only 5% or less of patients is it necessary to withdraw one or more drugs." | 2.36 | Short-course therapy for tuberculosis. ( Aquinas, M, 1982) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (25.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (25.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 1 (25.00) | 2.80 |
Authors | Studies |
---|---|
Danna, BJ | 1 |
Harvey, AW | 1 |
Woc-Colburn, LE | 1 |
Ricks, PM | 1 |
Hershow, RC | 1 |
Rahimian, A | 1 |
Huo, D | 1 |
Johnson, W | 1 |
Prachand, N | 1 |
Jimenez, A | 1 |
Wiebel, W | 1 |
Paul, W | 1 |
Ijaz, K | 1 |
Jereb, JA | 1 |
Lambert, LA | 1 |
Bower, WA | 1 |
Spradling, PR | 1 |
McElroy, PD | 1 |
Iademarco, MF | 1 |
Navin, TR | 1 |
Castro, KG | 1 |
Aquinas, M | 1 |
1 review available for pyrazinamide and Chemical Dependence
Article | Year |
---|---|
Short-course therapy for tuberculosis.
Topics: Drug Therapy, Combination; Humans; Pyrazinamide; Rifampin; Streptomycin; Substance-Related Disorders | 1982 |
1 trial available for pyrazinamide and Chemical Dependence
Article | Year |
---|---|
A randomized trial comparing standard outcomes in two treatment models for substance users with tuberculosis.
Topics: Adult; Antitubercular Agents; Directly Observed Therapy; Drug Users; Ethambutol; Ethnicity; Female; | 2015 |
2 other studies available for pyrazinamide and Chemical Dependence
Article | Year |
---|---|
Esophageal Tuberculosis - A Mass of Confusion.
Topics: Aged; Antitubercular Agents; Deglutition Disorders; Delayed Diagnosis; Diagnosis, Differential; Dire | 2020 |
Severe or fatal liver injury in 50 patients in the United States taking rifampin and pyrazinamide for latent tuberculosis infection.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Antitubercular Agents; Chemical and Drug Induced Liver In | 2006 |