Page last updated: 2024-10-20

pyrazinamide and Brain Disorders

pyrazinamide has been researched along with Brain Disorders in 7 studies

pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.

Research Excerpts

ExcerptRelevanceReference
"35 children with suspected tuberculomas of the brain were given a therapeutic 4-drug trial of isoniazid, rifampicin, pyrazinamide and ethambutol."5.06Intracranial tuberculomas. An assessment of a therapeutic 4-drug trial in 35 children. ( Domingo, Z; Peter, JC, 1989)
"Intracranial tuberculomas are rare yet lethal forms of tuberculosis."2.66Multiple tuberculomas in an immunocompetent patient and their diagnostic challenge in a high prevalence country: Case report and literature review. ( Alva-Diaz, C; Esteban-Arias, D; López-Saavedra, A; Metcalf, T; Orellana-Tovar, I; Pacheco-Barrios, K; Rodriguez-López, E; Velásquez-Rimachi, V, 2020)
"One patient presented with attacks of hydrocephalus initially diagnosed erroneously as migraine, another had multiple tuberculomas and a fourth tuberculoma became apparent during treatment with antituberculous therapy."1.25Three patients with intracranial tuberculomas with unusual features. ( Barwick, DD; Thrush, DC, 1974)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Velásquez-Rimachi, V1
Orellana-Tovar, I1
Rodriguez-López, E1
López-Saavedra, A1
Esteban-Arias, D1
Pacheco-Barrios, K1
Metcalf, T1
Alva-Diaz, C1
Dubey, S1
Devi, BI1
Jawalkar, VK1
Bhat, DI1
Kwon, HM1
Kim, HK1
Cho, J1
Hong, YH1
Nam, H1
Mehta, JB1
Mejia, E1
Gallemore, GH1
Ramsey, GF1
Farrell, VJ1
Domingo, Z1
Peter, JC1
Thrush, DC1
Barwick, DD1

Reviews

2 reviews available for pyrazinamide and Brain Disorders

ArticleYear
Multiple tuberculomas in an immunocompetent patient and their diagnostic challenge in a high prevalence country: Case report and literature review.
    The Indian journal of tuberculosis, 2020, Volume: 67, Issue:3

    Topics: Antitubercular Agents; Blindness; Brain; Brain Diseases; Cerebellar Ataxia; Dexamethasone; Drug Ther

2020
Tuberculoma en plaque: a case report.
    Neurology India, 2002, Volume: 50, Issue:4

    Topics: Adolescent; Antitubercular Agents; Brain Diseases; Drug Therapy, Combination; Female; Humans; Isonia

2002

Trials

1 trial available for pyrazinamide and Brain Disorders

ArticleYear
Intracranial tuberculomas. An assessment of a therapeutic 4-drug trial in 35 children.
    Pediatric neuroscience, 1989, Volume: 15, Issue:4

    Topics: Adolescent; Antitubercular Agents; Brain Diseases; Child; Child, Preschool; Combined Modality Therap

1989

Other Studies

4 other studies available for pyrazinamide and Brain Disorders

ArticleYear
Cycloserine-induced encephalopathy: evidence on brain MRI.
    European journal of neurology, 2008, Volume: 15, Issue:7

    Topics: Aged; Antibiotics, Antitubercular; Brain Diseases; Cycloserine; Disorders of Excessive Somnolence; D

2008
Drug-resistant tuberculosis of the brain in a two-year-old child.
    Tennessee medicine : journal of the Tennessee Medical Association, 1998, Volume: 91, Issue:7

    Topics: Antibiotics, Antitubercular; Antitubercular Agents; Brain Diseases; Child, Preschool; Drug Therapy,

1998
Brain stem tuberculoma in adult patients: diagnosis and treatment.
    Surgical neurology, 1990, Volume: 34, Issue:6

    Topics: Adult; Brain Diseases; Drug Therapy, Combination; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide

1990
Three patients with intracranial tuberculomas with unusual features.
    Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:5

    Topics: Adolescent; Aminosalicylic Acids; Brain Diseases; Dexamethasone; Diabetic Coma; Electroencephalograp

1974