pyrazinamide has been researched along with Acquired Immune Deficiency Syndrome in 18 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mycobacterium tuberculosis infection has been shown to result in increased HIV replication and disease progression in HIV-infected individuals through increased immune activation." | 1.35 | Incomplete immunological recovery following anti-tuberculosis treatment in HIV-infected individuals with active tuberculosis. ( Hanna, LE; Narayanan, PR; Nayak, K; Subramanyam, S; Swaminathan, S; Venkatesan, P, 2009) |
| "He was diagnosed as pulmonary tuberculosis, and started treatment with INH, RFP, EB, and PZA." | 1.34 | [A case of tuberculosis showing immune reconstitution syndrome after the initiation of antiretroviral therapy for HIV infection]. ( Izumi, S; Taniguchi, H, 2007) |
| "Hyponatremia is seen in 40% to 60% of hospitalized acquired immune deficiency syndrome (AIDS) patients." | 1.31 | Normouricemia in the syndrome of inappropriate antidiuretic hormone secretion. ( Akalin, E; Chandrakantan, A; Hamburger, RJ; Keane, J, 2001) |
| "To test whether the bioavailability of antituberculosis drugs is altered in HIV-infected patients with tuberculosis." | 1.30 | Does AIDS impair the absorption of antituberculosis agents? ( Smith, PJ; Taylor, B, 1998) |
| "Pyrazinamide was administered at 1 g once daily for 5 days to 40 adult volunteers (10 men with AIDS, 10 normal men, 10 women with AIDS, and 10 normal women)." | 1.30 | Intrapulmonary concentrations of pyrazinamide. ( Conte, JE; Duncan, S; Golden, JA; McKenna, E; Zurlinden, E, 1999) |
| "There are few reports of children with AIDS and TB." | 1.29 | Clinical manifestation and outcome of tuberculosis in children with acquired immunodeficiency syndrome. ( Birnbaum, J; Chan, SP; Rao, M; Steiner, P, 1996) |
| "Forty-one of our patients had pulmonary tuberculosis, 38 had extra pulmonary and in 61 it was disseminated." | 1.28 | AIDS and tuberculosis in Spain. A report of 140 cases. ( Adrados, M; Díaz, F; García Aguado, C; González Lahoz, JM; Laguna, F; Martínez, R; Puente, S, 1991) |
| "Seven patients received no treatment because tuberculosis was first diagnosed after death." | 1.28 | Treatment of tuberculosis in patients with advanced human immunodeficiency virus infection. ( Chaisson, RE; Goodman, PC; Hopewell, PC; Sande, MA; Schecter, GF; Small, PM, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 11 (61.11) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hanna, LE | 1 |
| Nayak, K | 1 |
| Subramanyam, S | 1 |
| Venkatesan, P | 1 |
| Narayanan, PR | 1 |
| Swaminathan, S | 1 |
| Taniguchi, H | 1 |
| Izumi, S | 1 |
| Chan, SP | 1 |
| Birnbaum, J | 1 |
| Rao, M | 1 |
| Steiner, P | 1 |
| Brmbolić, BJ | 1 |
| Boricić, I | 1 |
| Salemović, DR | 1 |
| Jevtović, DL | 1 |
| Ranin, JT | 1 |
| Begić-Janeva, A | 1 |
| de Kantor, IN | 1 |
| Latini, O | 1 |
| Barrera, L | 1 |
| Taylor, B | 1 |
| Smith, PJ | 1 |
| Domoua, K | 1 |
| N'Dhatz, M | 1 |
| Coulibaly, G | 1 |
| Traore, F | 1 |
| Koffi, J | 1 |
| Achi, V | 1 |
| Daix, T | 1 |
| Ouattara, Y | 1 |
| Ouedraogo, M | 1 |
| Beugre, LK | 1 |
| Konan, JB | 1 |
| Coulibaly, V | 1 |
| Coulibaly, IM | 1 |
| Yapi, A | 1 |
| Conte, JE | 1 |
| Golden, JA | 1 |
| Duncan, S | 1 |
| McKenna, E | 1 |
| Zurlinden, E | 1 |
| Takahashi, T | 1 |
| Endou, T | 1 |
| Nakamura, T | 1 |
| Asai, S | 1 |
| Yoshikawa, K | 1 |
| Iwamoto, A | 1 |
| Akalin, E | 1 |
| Chandrakantan, A | 1 |
| Keane, J | 1 |
| Hamburger, RJ | 1 |
| Kura, MM | 1 |
| Hira, SK | 1 |
| Rabahi, MF | 1 |
| Rodrigues, AB | 1 |
| Queiroz de Mello, F | 1 |
| de Almeida Netto, JC | 1 |
| Kritski, AL | 1 |
| Pust, RE | 1 |
| Laguna, F | 1 |
| Adrados, M | 1 |
| Díaz, F | 1 |
| Martínez, R | 1 |
| García Aguado, C | 1 |
| Puente, S | 1 |
| González Lahoz, JM | 1 |
| Small, PM | 1 |
| Schecter, GF | 1 |
| Goodman, PC | 1 |
| Sande, MA | 1 |
| Chaisson, RE | 1 |
| Hopewell, PC | 1 |
| Pitchenik, AE | 1 |
| Tournier, G | 1 |
| Gallet, S | 1 |
| Bellon, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Simultaneous Versus Sequential Antiretroviral Therapy and Antituberculosis Treatment in Patients With AIDS and Active Tuberculosis. Open, Randomized and Controlled, Multisite Clinical Trial.[NCT00737724] | 63 participants (Actual) | Interventional | 2008-03-31 | Terminated (stopped due to Other published trials showed definitive expected superiority of Group 1) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyrazinamide and Acquired Immune Deficiency Syndrome
| Article | Year |
|---|---|
[Which treatment for primary tuberculosis?].
Topics: Acquired Immunodeficiency Syndrome; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Pyrazi | 1989 |
1 trial available for pyrazinamide and Acquired Immune Deficiency Syndrome
| Article | Year |
|---|---|
Reintroducing antituberculosis therapy after Stevens-Johnson syndrome in human immunodeficiency virus-infected patients with tuberculosis: role of desensitization.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antitubercular Age | 2001 |
16 other studies available for pyrazinamide and Acquired Immune Deficiency Syndrome
| Article | Year |
|---|---|
Incomplete immunological recovery following anti-tuberculosis treatment in HIV-infected individuals with active tuberculosis.
Topics: Acquired Immunodeficiency Syndrome; Analysis of Variance; beta 2-Microglobulin; Biomarkers; CD4-Posi | 2009 |
[A case of tuberculosis showing immune reconstitution syndrome after the initiation of antiretroviral therapy for HIV infection].
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Antitubercular Agents; Drug Therapy, Com | 2007 |
Clinical manifestation and outcome of tuberculosis in children with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; AIDS-Related Opportunistic Infections; Antibiotics, | 1996 |
Focal tuberculosis of the liver with local hemorrhage in a patient with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Ethambutol; Granuloma; Histocytochemistry; Homosexuality, | 1996 |
[Resistance and multiresistance to antitubercular drugs in Argentina and in other Latin American countries].
Topics: Acquired Immunodeficiency Syndrome; Antitubercular Agents; Argentina; Drug Resistance, Microbial; Dr | 1998 |
Does AIDS impair the absorption of antituberculosis agents?
Topics: Absorption; Acquired Immunodeficiency Syndrome; Adolescent; Adult; Antitubercular Agents; Biological | 1998 |
[Efficacy of a short 6 month therapeutic coursefor HIV infected tuberculosis patients in Abidjan, Côte d'Ivoire].
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Antitubercular Agents; Cohort Studies; Cote d | 1998 |
Intrapulmonary concentrations of pyrazinamide.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antitubercular Agents; Epithelium; Female; Humans; Lung; | 1999 |
Pulmonary nodule mimicking lung cancer in a human immunodeficiency virus type-1 infected patient.
Topics: Acquired Immunodeficiency Syndrome; Adenocarcinoma; Adult; Antitubercular Agents; Diagnosis, Differe | 1999 |
Normouricemia in the syndrome of inappropriate antidiuretic hormone secretion.
Topics: Acquired Immunodeficiency Syndrome; Ethambutol; Humans; Hyponatremia; Inappropriate ADH Syndrome; Lu | 2001 |
Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Antitubercular Agents; Brazil; Child; C | 2002 |
Tuberculosis in the 1990's: resurgence, regimens, and resources.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Child; Drug Administration Schedule; Drug Interacti | 1992 |
AIDS and tuberculosis in Spain. A report of 140 cases.
Topics: Acquired Immunodeficiency Syndrome; Drug Therapy, Combination; Ethambutol; Female; Humans; Incidence | 1991 |
Treatment of tuberculosis in patients with advanced human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Administration Schedule; Drug Therapy, Combination; | 1991 |
Tuberculosis control and the AIDS epidemic in developing countries.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Developing Countries; Diagnosis, Different | 1990 |
[Tuberculosis in children in 1989].
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Age Factors; Anti-Bacterial Agents; BCG Vaccine; Chi | 1989 |