pyrazinamide has been researched along with Abscess, Tubercular, Intracranial in 14 studies
pyrazinecarboxamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intracranial tuberculomas are rare yet lethal forms of tuberculosis." | 2.66 | Multiple tuberculomas in an immunocompetent patient and their diagnostic challenge in a high prevalence country: Case report and literature review. ( Alva-Diaz, C; Esteban-Arias, D; López-Saavedra, A; Metcalf, T; Orellana-Tovar, I; Pacheco-Barrios, K; Rodriguez-López, E; Velásquez-Rimachi, V, 2020) |
| "Isolated INH-resistant intracranial tuberculoma is rare in adults." | 1.37 | Isoniazid-resistant intracranial tuberculoma treated with a combination of moxifloxacin and first-line anti-tuberculosis medication. ( Achawal, S; Anderson, G; Lee, WY; Ling, M; Thaker, HK, 2011) |
| "A 65-year-old woman developed a confusional syndrome one week after starting treatment for pulmonary military tuberculosis." | 1.34 | [Aseptic cerebral venous thrombosis and multiple cerebral tuberculomas associated with pulmonary miliary tuberculosis]. ( Amara, B; Belahsen, MF; Benjelloun, FZ; Benjelloun, MC; Messouak, O; Tizniti, S, 2007) |
| "Intracranial tuberculoma is a possible complication of meningeal, miliary or pulmonary tuberculosis." | 1.33 | [Tuberculoma complicating tuberculous meningitis: description of one paediatric case]. ( Alosi, MM; Ruggeri, C; Scibilia, G; Valenzise, M; Wasniewska, M, 2005) |
| "Intracranial tuberculomas are a rare manifestation of neurotuberculosis and are due to hematogenous dissemination of distant focuses of Mycobacterium tuberculosis infection." | 1.31 | [Intracranial tuberculomas developing during treatment of pulmonary tuberculosis: case report]. ( Alves, SM; Belo Neto, E; Brandão, RZ; Novis, SA; Pimentel, ML, 2000) |
| "We report a case of multiple intracranial tuberculoma whose diagnosis was not made by CT-SBB but by OBB." | 1.30 | [A case of multiple intracranial tuberculoma diagnosed by open brain biopsy]. ( Fujihara, K; Itoyama, Y; Jin, K; Kinpara, T; Nagai, M; Sakuma, R; Shiga, Y, 1997) |
| "The incidence of intracranial tuberculoma was found to be higher in children and juvenile patients who lived in rural areas." | 1.29 | [CT scanning and treatment of intracranial tuberculoma]. ( Jiang, M; Wang, S; Yang, T, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Velásquez-Rimachi, V | 1 |
| Orellana-Tovar, I | 1 |
| Rodriguez-López, E | 1 |
| López-Saavedra, A | 1 |
| Esteban-Arias, D | 1 |
| Pacheco-Barrios, K | 1 |
| Metcalf, T | 1 |
| Alva-Diaz, C | 1 |
| Ishiwada, N | 1 |
| Tokunaga, O | 1 |
| Nagasawa, K | 1 |
| Ichimoto, K | 1 |
| Kinoshita, K | 1 |
| Hishiki, H | 1 |
| Kohno, Y | 1 |
| Molton, JS | 1 |
| Huggan, PJ | 1 |
| Archuleta, S | 1 |
| Yang, M | 1 |
| Zhang, JT | 1 |
| Yao, Y | 1 |
| Tan, QC | 1 |
| Gao, T | 1 |
| Tian, CL | 1 |
| Huang, X | 1 |
| Yu, SY | 1 |
| Thwaites, G | 1 |
| Fisher, M | 1 |
| Hemingway, C | 1 |
| Scott, G | 1 |
| Solomon, T | 1 |
| Innes, J | 1 |
| Wong, KK | 1 |
| Oliver, GF | 1 |
| Lee, WY | 1 |
| Ling, M | 1 |
| Anderson, G | 1 |
| Achawal, S | 1 |
| Thaker, HK | 1 |
| Ruggeri, C | 1 |
| Valenzise, M | 1 |
| Alosi, MM | 1 |
| Scibilia, G | 1 |
| Wasniewska, M | 1 |
| Messouak, O | 1 |
| Amara, B | 1 |
| Benjelloun, FZ | 1 |
| Tizniti, S | 1 |
| Benjelloun, MC | 1 |
| Belahsen, MF | 1 |
| Rajeswari, R | 1 |
| Sivasubramanian, S | 1 |
| Balambal, R | 1 |
| Parthasarathy, R | 1 |
| Ranjani, R | 1 |
| Santha, T | 1 |
| Somasundaram, PR | 1 |
| Ganapathy, S | 1 |
| Sudarsana, K | 1 |
| Sayeed, ZA | 1 |
| Poon, WS | 1 |
| Ahuja, A | 1 |
| Li, AK | 1 |
| Wang, S | 1 |
| Yang, T | 1 |
| Jiang, M | 1 |
| Sakuma, R | 1 |
| Jin, K | 1 |
| Nagai, M | 1 |
| Kinpara, T | 1 |
| Shiga, Y | 1 |
| Fujihara, K | 1 |
| Itoyama, Y | 1 |
| Pimentel, ML | 1 |
| Alves, SM | 1 |
| Novis, SA | 1 |
| Brandão, RZ | 1 |
| Belo Neto, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Double Blind Placebo Controlled Trial of Adjunctive Dexamethasone for the Treatment of HIV-infected Adults With Tuberculous Meningitis[NCT03092817] | Phase 3 | 520 participants (Actual) | Interventional | 2017-05-25 | Active, not recruiting | ||
| A Randomized Double Blind Placebo Controlled Non-inferiority Trial of Adjunctive Dexamethasone for the Treatment of HIV-uninfected Adults With Tuberculous Meningitis Stratified by Leukotriene A4 Hydrolase Genotype[NCT03100786] | Phase 3 | 640 participants (Anticipated) | Interventional | 2018-02-08 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyrazinamide and Abscess, Tubercular, Intracranial
| Article | Year |
|---|---|
Multiple tuberculomas in an immunocompetent patient and their diagnostic challenge in a high prevalence country: Case report and literature review.
Topics: Antitubercular Agents; Blindness; Brain; Brain Diseases; Cerebellar Ataxia; Dexamethasone; Drug Ther | 2020 |
1 trial available for pyrazinamide and Abscess, Tubercular, Intracranial
| Article | Year |
|---|---|
A controlled clinical trial of short-course chemotherapy for tuberculoma of the brain.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antitubercular Agents; Child; Drug Administration Sc | 1995 |
12 other studies available for pyrazinamide and Abscess, Tubercular, Intracranial
| Article | Year |
|---|---|
Isoniazid- and streptomycin-resistant miliary tuberculosis complicated by intracranial tuberculoma in a Japanese infant.
Topics: Antitubercular Agents; Drug Substitution; Drug Therapy, Combination; Ethambutol; Ethionamide; Female | 2013 |
Infliximab therapy in two cases of severe neurotuberculosis paradoxical reaction.
Topics: Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antitubercular Agents; Dexamethasone; Etham | 2015 |
A Clinical Study of Miliary Brain Tuberculomas in China.
Topics: Adult; Aged; Antitubercular Agents; Brain; Contrast Media; Drug Therapy, Combination; Ethambutol; Fe | 2016 |
British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children.
Topics: Adenosine Deaminase; Adult; Antibiotics, Antitubercular; Antitubercular Agents; Cerebrospinal Fluid; | 2009 |
British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children.
Topics: Adenosine Deaminase; Adult; Antibiotics, Antitubercular; Antitubercular Agents; Cerebrospinal Fluid; | 2009 |
British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children.
Topics: Adenosine Deaminase; Adult; Antibiotics, Antitubercular; Antitubercular Agents; Cerebrospinal Fluid; | 2009 |
British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children.
Topics: Adenosine Deaminase; Adult; Antibiotics, Antitubercular; Antitubercular Agents; Cerebrospinal Fluid; | 2009 |
Simultaneous scrofuloderma and intracranial tuberculomas: a rare presentation of systemic tuberculosis.
Topics: Antitubercular Agents; Aza Compounds; Brain; Diagnosis, Differential; Drug Therapy, Combination; Flu | 2010 |
Isoniazid-resistant intracranial tuberculoma treated with a combination of moxifloxacin and first-line anti-tuberculosis medication.
Topics: Antitubercular Agents; Aza Compounds; Biopsy; Brain; Cerebrospinal Fluid; Drug Resistance, Bacterial | 2011 |
[Tuberculoma complicating tuberculous meningitis: description of one paediatric case].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibiotics, Antitubercular; Antitubercular Agents; | 2005 |
[Aseptic cerebral venous thrombosis and multiple cerebral tuberculomas associated with pulmonary miliary tuberculosis].
Topics: Acenocoumarol; Aged; Anticoagulants; Antitubercular Agents; Confusion; Drug Therapy, Combination; Fe | 2007 |
Optochiasmatic tuberculoma causing progressive visual failure: when has medical treatment failed?
Topics: Child, Preschool; Dexamethasone; Drug Therapy, Combination; Female; Humans; Isoniazid; Mental Disord | 1993 |
[CT scanning and treatment of intracranial tuberculoma].
Topics: Adolescent; Animals; Antitubercular Agents; Child; Drug Therapy, Combination; Ethambutol; Female; Hu | 1996 |
[A case of multiple intracranial tuberculoma diagnosed by open brain biopsy].
Topics: Antitubercular Agents; Biopsy; Brain; Ethambutol; Humans; Immunocompromised Host; Isoniazid; Male; M | 1997 |
[Intracranial tuberculomas developing during treatment of pulmonary tuberculosis: case report].
Topics: Adult; Antitubercular Agents; Humans; Isoniazid; Magnetic Resonance Imaging; Male; Pyrazinamide; Rif | 2000 |