pwz-029 and Psychomotor-Agitation

pwz-029 has been researched along with Psychomotor-Agitation* in 1 studies

Other Studies

1 other study(ies) available for pwz-029 and Psychomotor-Agitation

Article	Year
Negative allosteric modulation of alpha 5-containing GABA Psychopharmacology, 2018, Volume: 235, Issue:4 Associated with frank neuropathology, patients with Alzheimer's disease suffer from a host of neuropsychiatric symptoms that include depression, apathy, agitation, and aggression. Negative allosteric modulators (NAMs) of α5-containing GABA. We utilized electrophysiological recordings from Xenopus oocytes and behavioral measures in mice to address this hypothesis.. In the forced-swim assay in mice that detects antidepressant drugs, the α5β3γ2 GABA. α5βγ2 GABA Topics: Aging; Allosteric Regulation; Animals; Antidepressive Agents; Benzodiazepines; Depressive Disorder; Dose-Response Relationship, Drug; Female; Flumazenil; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Psychomotor Agitation; Receptors, GABA-A; tau Proteins; Xenopus laevis	2018

Article

Year

Negative allosteric modulation of alpha 5-containing GABA

Psychopharmacology, 2018, Volume: 235, Issue:4

Associated with frank neuropathology, patients with Alzheimer's disease suffer from a host of neuropsychiatric symptoms that include depression, apathy, agitation, and aggression. Negative allosteric modulators (NAMs) of α5-containing GABA. We utilized electrophysiological recordings from Xenopus oocytes and behavioral measures in mice to address this hypothesis.. In the forced-swim assay in mice that detects antidepressant drugs, the α5β3γ2 GABA. α5βγ2 GABA

Topics: Aging; Allosteric Regulation; Animals; Antidepressive Agents; Benzodiazepines; Depressive Disorder; Dose-Response Relationship, Drug; Female; Flumazenil; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Psychomotor Agitation; Receptors, GABA-A; tau Proteins; Xenopus laevis

2018