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putrescine and Trypanosomiasis, African

putrescine has been researched along with Trypanosomiasis, African in 5 studies

Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.

Research Excerpts

ExcerptRelevanceReference
"The treatment of late-stage human African trypanosomiasis is complicated by a post-treatment reactive encephalopathy, also referred to as a 'reactive arsenical encephalopathy', that may be fatal."1.30The role of the polyamine inhibitor eflornithine in the neuropathogenesis of experimental murine African trypanosomiasis. ( Burke, JM; Gichuki, CW; Hunter, CA; Jennings, FW; Kennedy, PG; Murray, M; Rodgers, J, 1997)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nishimura, K1
Yanase, T1
Araki, N1
Ohnishi, Y1
Kozaki, S1
Shima, K1
Asakura, M1
Samosomsuk, W1
Yamasaki, S1
Jennings, FW1
Gichuki, CW1
Kennedy, PG1
Rodgers, J1
Hunter, CA1
Murray, M1
Burke, JM1
Mutomba, MC1
Li, F1
Gottesdiener, KM1
Wang, CC1
Giffin, BF1
McCann, PP2
Bitonti, AJ1
Bacchi, CJ1
Sjoerdsma, A1

Other Studies

5 other studies available for putrescine and Trypanosomiasis, African

ArticleYear
Effects of polyamines on two strains of Trypanosoma brucei in infected rats and in vitro culture.
    The Journal of parasitology, 2006, Volume: 92, Issue:2

    Topics: Amide Synthases; Animals; Culture Media; Eflornithine; Enzyme Inhibitors; Gene Expression Regulation

2006
The role of the polyamine inhibitor eflornithine in the neuropathogenesis of experimental murine African trypanosomiasis.
    Neuropathology and applied neurobiology, 1997, Volume: 23, Issue:3

    Topics: Animals; Brain; Brain Diseases; Diminazene; Eflornithine; Female; Mice; Mice, Inbred Strains; Polyam

1997
A Trypanosoma brucei bloodstream form mutant deficient in ornithine decarboxylase can protect against wild-type infection in mice.
    Experimental parasitology, 1999, Volume: 91, Issue:2

    Topics: Africa South of the Sahara; Animals; Antibodies, Monoclonal; Blotting, Western; Disease Models, Anim

1999
Physiological activation of the mitochondrion and the transformation capacity of DFMO induced intermediate and short stumpy bloodstream form trypanosomes.
    The American journal of tropical medicine and hygiene, 1989, Volume: 40, Issue:5

    Topics: Animals; Dihydrolipoamide Dehydrogenase; Eflornithine; Histocytochemistry; Male; Microscopy, Electro

1989
Catalytic irreversible inhibition of Trypanosoma brucei brucei ornithine decarboxylase by substrate and product analogs and their effects on murine trypanosomiasis.
    Biochemical pharmacology, 1985, May-15, Volume: 34, Issue:10

    Topics: Animals; Eflornithine; Kinetics; Male; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Ra

1985