putrescine has been researched along with Skin Neoplasms in 16 studies
Skin Neoplasms: Tumors or cancer of the SKIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ethyl acetate extract of the acetone-soluble Aloe arborescens fraction was found to inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear oedema, putrescine increase and tumour promotion in mouse skin." | 7.71 | Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin. ( Beppu, H; Chihara, T; Ida, C; Kaneko, T; Kuzuya, H; Shimpo, K, 2002) |
| "As a result of bioassay-guided fractionation, betulinic acid, a pentacyclic triterpene, was identified as a melanoma-specific cytotoxic agent." | 7.69 | Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis. ( Beecher, CW; Brown, DM; Chagwedera, TE; Chai, H; Cordell, GA; Farnsworth, NR; Fong, HH; Kinghorn, AD; Lee, IS; Pisha, E, 1995) |
| "The ethyl acetate extract of the acetone-soluble Aloe arborescens fraction was found to inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear oedema, putrescine increase and tumour promotion in mouse skin." | 3.71 | Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin. ( Beppu, H; Chihara, T; Ida, C; Kaneko, T; Kuzuya, H; Shimpo, K, 2002) |
| "As a result of bioassay-guided fractionation, betulinic acid, a pentacyclic triterpene, was identified as a melanoma-specific cytotoxic agent." | 3.69 | Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis. ( Beecher, CW; Brown, DM; Chagwedera, TE; Chai, H; Cordell, GA; Farnsworth, NR; Fong, HH; Kinghorn, AD; Lee, IS; Pisha, E, 1995) |
| "Putrescine was decreased in MEK/AZ tumors, while spermidine and spermine levels were unaffected, suggesting that the primary role played by AZ in this system is to inhibit putrescine accumulation." | 1.33 | Tumor suppressor activity of ODC antizyme in MEK-driven skin tumorigenesis. ( Feith, DJ; Origanti, S; Sass-Kuhn, S; Shantz, LM; Shoop, PL, 2006) |
| "However, DFMO treatment led to marked hair loss in PKC epsilon transgenic mice." | 1.32 | Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss. ( Ness, KJ; Oberley, TD; Verma, AK; Wheeler, DL, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (18.75) | 18.7374 |
| 1990's | 6 (37.50) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayes, CS | 1 |
| DeFeo-Mattox, K | 1 |
| Woster, PM | 1 |
| Gilmour, SK | 1 |
| Shimpo, K | 1 |
| Ida, C | 1 |
| Chihara, T | 1 |
| Beppu, H | 1 |
| Kaneko, T | 1 |
| Kuzuya, H | 1 |
| Wheeler, DL | 1 |
| Ness, KJ | 1 |
| Oberley, TD | 1 |
| Verma, AK | 3 |
| García-Fernández, AJ | 1 |
| Rodríguez, RA | 1 |
| Pérez-Pertejo, Y | 1 |
| Balaña-Fouce, R | 1 |
| Feith, DJ | 1 |
| Origanti, S | 1 |
| Shoop, PL | 1 |
| Sass-Kuhn, S | 1 |
| Shantz, LM | 1 |
| Takigawa, M | 1 |
| Simsiman, RC | 1 |
| Boutwell, RK | 2 |
| Weekes, RG | 1 |
| Pisha, E | 1 |
| Chai, H | 1 |
| Lee, IS | 1 |
| Chagwedera, TE | 1 |
| Farnsworth, NR | 1 |
| Cordell, GA | 1 |
| Beecher, CW | 1 |
| Fong, HH | 1 |
| Kinghorn, AD | 1 |
| Brown, DM | 1 |
| Savouré, N | 1 |
| Briand, G | 1 |
| Amory-Touz, MC | 1 |
| Combre, A | 1 |
| Maudet, M | 1 |
| Nicol, M | 1 |
| O'Brien, TG | 3 |
| Megosh, LC | 2 |
| Gilliard, G | 2 |
| Soler, AP | 1 |
| Peralta Soler, A | 1 |
| Megosh, L | 1 |
| George, K | 1 |
| Arbeit, JM | 1 |
| Riley, RR | 1 |
| Huey, B | 1 |
| Porter, C | 1 |
| Kelloff, G | 1 |
| Lubet, R | 1 |
| Ward, JM | 1 |
| Pinkel, D | 1 |
| Pietilä, M | 1 |
| Parkkinen, JJ | 1 |
| Alhonen, L | 1 |
| Jänne, J | 1 |
| Coleman, CS | 1 |
| Pegg, AE | 1 |
| Guo, Y | 1 |
| Sawicki, JA | 1 |
| Pavel, P | 1 |
| Schwippelová, Z | 1 |
| Gonzalez, GG | 1 |
| Byus, CV | 1 |
1 review available for putrescine and Skin Neoplasms
| Article | Year |
|---|---|
[Polyamines and malignant melanoma (author's transl)].
Topics: Animals; Humans; Mammals; Melanoma; Polyamines; Putrescine; Skin Neoplasms; Spermidine; Spermine | 1979 |
15 other studies available for putrescine and Skin Neoplasms
| Article | Year |
|---|---|
Elevated ornithine decarboxylase activity promotes skin tumorigenesis by stimulating the recruitment of bulge stem cells but not via toxic polyamine catabolic metabolites.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Hair | 2014 |
Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aloe; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Ea | 2002 |
Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss.
Topics: Administration, Oral; Alopecia; Animals; Benz(a)Anthracenes; Carcinogens; Carcinoma, Squamous Cell; | 2003 |
Characterization of putrescine uptake in hamster amelanocytic melanoma AMEL-3 cells.
Topics: Amidines; Animals; Biological Transport; Cell Cycle; Cricetinae; Dose-Response Relationship, Drug; D | 2005 |
Tumor suppressor activity of ODC antizyme in MEK-driven skin tumorigenesis.
Topics: Animals; Cell Cycle; Cell Proliferation; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Mice, | 2006 |
Polyamine biosynthesis and skin tumor promotion: inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase alpha-difluoromethylornithine.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Drug Antagonism; Eflornithine; Kinetics; | 1982 |
Inhibition by putrescine of the induction of epidermal ornithine decarboxylase activity and tumor promotion caused by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cocarcinogenesis; Enzyme Induction; Epide | 1980 |
Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; DNA Damage; Growth Inhibitors | 1995 |
Vitamin A status and metabolism of cutaneous polyamines in the hairless mouse after UV irradiation: action of beta-carotene and astaxanthin.
Topics: Animals; beta Carotene; Carotenoids; Epidermis; Female; Food, Fortified; Liver; Mice; Mice, Hairless | 1995 |
Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Animals, Newborn; Benzo(a)pyrene; Hair Folli | 1997 |
Polyamines regulate expression of the neoplastic phenotype in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Apoptosis; Carcinoma, Papillary; Carcin | 1998 |
Difluoromethylornithine chemoprevention of epidermal carcinogenesis in K14-HPV16 transgenic mice.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Disease Progressio | 1999 |
Relation of skin polyamines to the hairless phenotype in transgenic mice overexpressing spermidine/spermine N-acetyltransferase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetyltransferases; Aging; Alopecia; Animals; Animals, Newborn; Ca | 2001 |
Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetyltransferases; Animals; Animals, Genetically Modified; Carcin | 2002 |
Effect of dietary arginine restriction upon ornithine and polyamine metabolism during two-stage epidermal carcinogenesis in the mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arginine; DNA; Female; Mice; Ornithine; Ornithine Decarbo | 1991 |