Page last updated: 2024-10-20

putrescine and Neurodegenerative Diseases

putrescine has been researched along with Neurodegenerative Diseases in 6 studies

Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.

Research Excerpts

ExcerptRelevanceReference
" Previous studies from our laboratory demonstrated that spermine oxidase (SMOX, a member of the polyamine oxidase family) inhibition using MDL 72527 reduced neurodegeneration in models of retinal excitotoxicity and diabetic retinopathy."4.12Pharmacological Inhibition of Spermine Oxidase Suppresses Excitotoxicity Induced Neuroinflammation in Mouse Retina. ( Alfarhan, M; Liu, F; Narayanan, SP; Pichavaram, P; Shan, S; Somanath, PR, 2022)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
de Medina, P1
Paillasse, MR1
Payré, B1
Silvente-Poirot, S1
Poirot, M1
Alfarhan, M1
Liu, F1
Shan, S1
Pichavaram, P1
Somanath, PR1
Narayanan, SP1
Lai, TS1
Tucker, T1
Burke, JR1
Strittmatter, WJ1
Greenberg, CS1
Wood, PL1
Khan, MA1
Kulow, SR1
Mahmood, SA1
Moskal, JR1
Igarashi, S1
Koide, R1
Shimohata, T1
Yamada, M1
Hayashi, Y1
Takano, H1
Date, H1
Oyake, M1
Sato, T1
Sato, A1
Egawa, S1
Ikeuchi, T1
Tanaka, H1
Nakano, R1
Tanaka, K1
Hozumi, I1
Inuzuka, T1
Takahashi, H1
Tsuji, S1
Vivó, M1
de Vera, N1
Cortés, R1
Mengod, G1
Camón, L1
Martínez, E1

Other Studies

6 other studies available for putrescine and Neurodegenerative Diseases

ArticleYear
Synthesis of new alkylaminooxysterols with potent cell differentiating activities: identification of leads for the treatment of cancer and neurodegenerative diseases.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: Amines; Animals; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cholestanols; Dendrites; Dru

2009
Pharmacological Inhibition of Spermine Oxidase Suppresses Excitotoxicity Induced Neuroinflammation in Mouse Retina.
    International journal of molecular sciences, 2022, Feb-15, Volume: 23, Issue:4

    Topics: Animals; Antioxidants; Diabetic Retinopathy; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL;

2022
Effect of tissue transglutaminase on the solubility of proteins containing expanded polyglutamine repeats.
    Journal of neurochemistry, 2004, Volume: 88, Issue:5

    Topics: Biotinylation; Calcium; Catalysis; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Histam

2004
Neurotoxicity of reactive aldehydes: the concept of "aldehyde load" as demonstrated by neuroprotection with hydroxylamines.
    Brain research, 2006, Jun-20, Volume: 1095, Issue:1

    Topics: Aldehydes; Animals; Behavior, Animal; Cell Line; Cyclic N-Oxides; Disease Models, Animal; Dose-Respo

2006
Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch.
    Nature genetics, 1998, Volume: 18, Issue:2

    Topics: Animals; Apoptosis; Base Sequence; Cadaverine; COS Cells; Cystamine; DNA Primers; Enzyme Inhibitors;

1998
Polyamines in the basal ganglia of human brain. Influence of aging and degenerative movement disorders.
    Neuroscience letters, 2001, May-18, Volume: 304, Issue:1-2

    Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Basal Ganglia; Biogenic Polyamines; Female; Hu

2001