putrescine has been researched along with Liver Neoplasms in 26 studies
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As a result of bioassay-guided fractionation, betulinic acid, a pentacyclic triterpene, was identified as a melanoma-specific cytotoxic agent." | 7.69 | Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis. ( Beecher, CW; Brown, DM; Chagwedera, TE; Chai, H; Cordell, GA; Farnsworth, NR; Fong, HH; Kinghorn, AD; Lee, IS; Pisha, E, 1995) |
| "The effects of unilateral hydronephrosis by ligation of the right ureter and/or multiple injections of putrescine on kidney tumorigenesis by a single intrarenal injection of N-nitrosodimethylamine (DMN) were studied." | 7.66 | Modulation of N-nitrosodimethylamine kidney tumorigenesis by unilateral hydronephrosis and multiple putrescine administrations. ( Ohmori, T; Tabei, R, 1983) |
| "As a result of bioassay-guided fractionation, betulinic acid, a pentacyclic triterpene, was identified as a melanoma-specific cytotoxic agent." | 3.69 | Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis. ( Beecher, CW; Brown, DM; Chagwedera, TE; Chai, H; Cordell, GA; Farnsworth, NR; Fong, HH; Kinghorn, AD; Lee, IS; Pisha, E, 1995) |
| "The effects of unilateral hydronephrosis by ligation of the right ureter and/or multiple injections of putrescine on kidney tumorigenesis by a single intrarenal injection of N-nitrosodimethylamine (DMN) were studied." | 3.66 | Modulation of N-nitrosodimethylamine kidney tumorigenesis by unilateral hydronephrosis and multiple putrescine administrations. ( Ohmori, T; Tabei, R, 1983) |
| "Putrescine treatment (100pmol/L) raised MAT2A mRNA level to 4." | 1.39 | Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer. ( Giordano, P; Lu, SC; Mato, JM; Ryoo, M; Skay, A; Tomasi, I; Tomasi, ML, 2013) |
| "Isoornithines were not taken up by H-35 hepatoma cells; hence they did not affect their ODC activity." | 1.29 | Synthesis of isoornithines and methylputrescines. An evaluation of their inhibitory effects on ornithine decarboxylase. ( Aizencang, G; Frydman, B; Frydman, RB; Giorgieri, S; Guerra, L; Sambrotta, L, 1995) |
| "Polyamine content of colorectal cancers was independent of tumour site, Dukes' stage, histological grade and the presence of palpable liver metastases at laparotomy." | 1.27 | Polyamines in colorectal cancer. ( Kingsnorth, AN; Lumsden, AB; Wallace, HM, 1984) |
| "(c) Spermine levels were significantly lowered, with 3 minima corresponding to the putrescine maxima." | 1.26 | Intrahepatic polyamine levels during rat liver carcinogenesis induced by N-2-fluorenylacetamide. ( Aussel, C; Lafaurie, M; Lalanne, CM; Milano, G; Soula, G; Stora, C, 1981) |
| "Kinetic analyses showed that liver and hepatoma enzymes had a similar Km and Vmax for putrescine incorporation into cell protein." | 1.26 | Differential transglutaminase distribution in normal rat liver and rat hepatoma. ( Birckbichler, PJ; Orr, GR; Patterson, MK, 1976) |
| "Quiescent, contact inhibited H-35 rat hepatoma cell cultures maintained in minimal essential medium contain a very low level of ornithine decarboxylase activity." | 1.26 | The appearance of an ornithine decarboxylase inhibitory protein upon the addition of putrescine to cell cultures. ( Canellakis, ES; Fong, WF; Heller, JS, 1976) |
| "All 6 patients with localized malignant tumors had elevated urinary polyamine levels." | 1.25 | Urinary polyamine levels in human cancer. ( Kessler, GF; Lipton, A; Sheehan, LM, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (73.08) | 18.7374 |
| 1990's | 5 (19.23) | 18.2507 |
| 2000's | 1 (3.85) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aizencang, G | 1 |
| Frydman, RB | 1 |
| Giorgieri, S | 1 |
| Sambrotta, L | 1 |
| Guerra, L | 1 |
| Frydman, B | 1 |
| Tomasi, ML | 1 |
| Ryoo, M | 1 |
| Skay, A | 1 |
| Tomasi, I | 1 |
| Giordano, P | 1 |
| Mato, JM | 1 |
| Lu, SC | 1 |
| Ohmori, T | 1 |
| Tabei, R | 1 |
| Kingsnorth, AN | 1 |
| Lumsden, AB | 1 |
| Wallace, HM | 1 |
| Milano, G | 1 |
| Aussel, C | 1 |
| Stora, C | 1 |
| Lafaurie, M | 1 |
| Soula, G | 1 |
| Lalanne, CM | 1 |
| Pisha, E | 1 |
| Chai, H | 1 |
| Lee, IS | 1 |
| Chagwedera, TE | 1 |
| Farnsworth, NR | 1 |
| Cordell, GA | 1 |
| Beecher, CW | 1 |
| Fong, HH | 1 |
| Kinghorn, AD | 1 |
| Brown, DM | 1 |
| Santos, AA | 1 |
| Stubbs, AP | 1 |
| Maghsoudloo, M | 1 |
| Murphy, GM | 1 |
| Wilkinson, ML | 1 |
| Taguchi, T | 1 |
| Kurata, S | 1 |
| Ohashi, M | 1 |
| Birckbichler, PJ | 1 |
| Orr, GR | 1 |
| Patterson, MK | 1 |
| Scalabrino, G | 1 |
| Pösö, H | 1 |
| Hölttä, E | 2 |
| Hannonen, P | 1 |
| Kallio, A | 1 |
| Jänne, J | 3 |
| Lipton, A | 1 |
| Sheehan, LM | 1 |
| Kessler, GF | 1 |
| McCann, PP | 2 |
| Tardiff, C | 1 |
| Mamont, PS | 2 |
| Schuber, F | 1 |
| Russell, DH | 2 |
| Looney, WB | 2 |
| Kovacs, CJ | 2 |
| Hopkins, HA | 2 |
| Dattilo, JW | 1 |
| Morris, HP | 2 |
| Katsuta, H | 1 |
| Takaoka, T | 1 |
| Nose, K | 1 |
| Nagai, Y | 1 |
| Fong, WF | 1 |
| Heller, JS | 1 |
| Canellakis, ES | 1 |
| Tardif, C | 1 |
| Perin, A | 1 |
| Sessa, A | 1 |
| Guha, SK | 1 |
| Oka, T | 1 |
| Takeda, T | 1 |
| Nishiguchi, S | 1 |
| Kuroki, T | 1 |
| Kobayashi, K | 1 |
| Hasuma, T | 1 |
| Matsui-Yuasa, I | 1 |
| Otani, S | 1 |
| Bowlin, TL | 1 |
| Rosenberger, A | 1 |
| Stemerick, D | 1 |
| Edwards, ML | 1 |
| Williams-Ashman, HG | 2 |
| Coppoc, GL | 2 |
| Weber, G | 1 |
| Geroch, ME | 1 |
| Schenone, A | 1 |
| Harik, SI | 1 |
| Hollenberg, MD | 1 |
| Snyder, SH | 1 |
| Marton, LJ | 1 |
| LeGendre, SM | 1 |
| Andersson, G | 1 |
| Heby, O | 1 |
3 reviews available for putrescine and Liver Neoplasms
| Article | Year |
|---|---|
Polyamines in mammalian liver during growth and development.
Topics: Animals; Chick Embryo; Hormones; Humans; Liver; Liver Neoplasms; Liver Regeneration; Mammals; Ornith | 1976 |
[Some new aspects of the function of spermidine in animal cells].
Topics: Adenosylmethionine Decarboxylase; Animals; Breast; Cell Division; Chick Embryo; Female; Glucocortico | 1975 |
New aspects of polyamine biosynthesis in eukaryotic organisms.
Topics: Animals; Azotobacter; Carboxy-Lyases; Carcinoma, Hepatocellular; Catalysis; Chickens; Escherichia co | 1972 |
23 other studies available for putrescine and Liver Neoplasms
| Article | Year |
|---|---|
Synthesis of isoornithines and methylputrescines. An evaluation of their inhibitory effects on ornithine decarboxylase.
Topics: Animals; Binding, Competitive; Carcinoma, Hepatocellular; Enzyme Inhibitors; Liver; Liver Neoplasms; | 1995 |
Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer.
Topics: Aged; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Female; Humans; Liver Neop | 2013 |
Modulation of N-nitrosodimethylamine kidney tumorigenesis by unilateral hydronephrosis and multiple putrescine administrations.
Topics: Animals; Body Weight; Dimethylnitrosamine; Female; gamma-Glutamyltransferase; Hydronephrosis; Kidney | 1983 |
Polyamines in colorectal cancer.
Topics: Aged; Colonic Neoplasms; Female; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Polya | 1984 |
Intrahepatic polyamine levels during rat liver carcinogenesis induced by N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Body Weight; Female; Liver Neoplasms; Neoplasms, Experimental; Organ | 1981 |
Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; DNA Damage; Growth Inhibitors | 1995 |
Polyamine metabolism in human hepatocellular cancer cells (Hep-G2).
Topics: Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; DNA, Neoplasm; Eflornithine; Humans; Liv | 1994 |
Effects of polyamines on DNA synthesis using various subcellular DNA polymerases extracted from normal rat liver, tumour-bearing rat liver, and tumour cells.
Topics: Animals; Cadaverine; Cytoplasm; DNA; DNA-Directed DNA Polymerase; Dose-Response Relationship, Drug; | 2001 |
Differential transglutaminase distribution in normal rat liver and rat hepatoma.
Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Cytoplasm; Fema | 1976 |
Synthesis and accumulation of polyamines in rat liver during chemical carcinogenesis.
Topics: Adenosylmethionine Decarboxylase; Animals; Carcinogens; Glucagon; Growth Hormone; Hydrocortisone; Li | 1978 |
Urinary polyamine levels in human cancer.
Topics: Adenocarcinoma; Adenoma; Bone Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous | 1975 |
Biphasic induction of ornithine decarboxylase and putrescine levels in growing HTC cells.
Topics: Animals; Blood; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cattle; Cell Line; | 1975 |
Changes in serum putrescine and spermidine levels following local radiation to hepatoma 3924A of the rat.
Topics: Animals; Carcinoma, Hepatocellular; Female; Liver Neoplasms; Neoplasms, Experimental; Putrescine; Ra | 1976 |
Effects of polyamines on the proliferation of mammalian cells in tissue culture.
Topics: Agmatine; Animals; Carcinoma, Hepatocellular; Cell Division; Culture Techniques; Fibroblasts; Liver; | 1975 |
The appearance of an ornithine decarboxylase inhibitory protein upon the addition of putrescine to cell cultures.
Topics: Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Culture Media; Cycloheximide; Dactinomycin; Ki | 1976 |
Regulation of ornithine decarboxylase by ODC-antizyme in HTC cells.
Topics: Cadaverine; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Dose- | 1977 |
Changes in polyamine levels and protein synthesis rate during rat liver carcinogenesis induced by 4-dimethylaminoazobenzene.
Topics: Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Male; Neoplasm Proteins; Neoplasms, Experimenta | 1978 |
Reduction by interferon-alpha of levels of c-myc protein and DNA synthesis in a human hepatoma cell line mediated by inhibition of putrescine synthesis.
Topics: Blotting, Northern; Carcinoma, Hepatocellular; Cell Line; DNA Replication; Humans; Interferon Type I | 1991 |
Potentiation of natural killer cell activity and tumor immunity by diacetylputrescine.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Colonic Neoplasms; Cytotoxicity, Immunolo | 1990 |
Imbalance in ornithine metabolism in hepatomas of different growth rates as expressed in formation of putrescine, spermidine, and spermine.
Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Electrophoresis, Paper; Liver; Liver Neoplasms; | 1972 |
Alpha-hydrazino-ornithine blocks net synthesis of putrescine but not of RNA and DNA.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Depression, Chemical; DNA; Hepatectomy; Hydrazi | 1974 |
Polyamine depletion of tumor tissue and subsequent elevation of spermidine in the sera of rats with 3924A hepatomas after 5-fluorouracil administration.
Topics: Animals; Carcinoma, Hepatocellular; Female; Fluorouracil; Liver; Liver Neoplasms; Neoplasms, Experim | 1974 |
Polyamine and nucleic acid concentrations in Ehrlich ascites carcinoma cells and liver of tumor-bearing mice at various stages of tumor growth.
Topics: Animals; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred S | 1972 |