putrescine has been researched along with Leukemia L 1210 in 34 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Putrescine was similarly ineffective, supporting growth at 13% of control and viability at 7%." | 1.28 | Cellular characterization of a new irreversible inhibitor of S-adenosylmethionine decarboxylase and its use in determining the relative abilities of individual polyamines to sustain growth and viability of L1210 cells. ( Bukin, YV; Khomutov, AR; Khomutov, RM; Kramer, DL; Porter, CW, 1989) |
| "When putrescine was combined concurrently with VP-16, both the in vitro cytotoxic effects and the number of DNA SSBs in L1210 cells were significantly reduced." | 1.27 | Modulation of etoposide cytotoxicity and DNA strand scission in L1210 and 8226 cells by polyamines. ( Dorr, RT; Gerner, EW; Liddil, JD, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (55.88) | 18.7374 |
| 1990's | 15 (44.12) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lakanen, JR | 2 |
| Coward, JK | 2 |
| Pegg, AE | 6 |
| Tomasi, S | 1 |
| Le Roch, M | 1 |
| Renault, J | 3 |
| Corbel, JC | 1 |
| Uriac, P | 2 |
| Carboni, B | 1 |
| Moncoq, D | 1 |
| Martin, B | 1 |
| Delcros, JG | 3 |
| LEE, WW | 1 |
| BERRIDGE, BJ | 1 |
| ROSS, LO | 1 |
| GOODMAN, L | 1 |
| Cavanaugh, PF | 1 |
| Pavelic, ZP | 1 |
| Porter, CW | 7 |
| Byczkowski, JZ | 1 |
| Bergeron, RJ | 2 |
| Poulin, R | 4 |
| Pelletier, G | 1 |
| Grillo, MA | 1 |
| Colombatto, S | 1 |
| Stjernborg, L | 1 |
| Heby, O | 4 |
| Mamont, P | 1 |
| Persson, L | 2 |
| Khomutov, AR | 2 |
| Shvetsov, AS | 1 |
| Vepsalainen, J | 1 |
| Dramer, DL | 1 |
| Hyvonen, T | 1 |
| Keinanen, T | 1 |
| Eloranta, TO | 1 |
| Khomutov, RM | 2 |
| Vaultier, M | 2 |
| Le Roch, N | 2 |
| Havouis, R | 3 |
| Moulinoux, JP | 3 |
| Seiler, N | 3 |
| Douaud, F | 2 |
| Wang, Z | 1 |
| Fries, D | 1 |
| Blankenship, J | 1 |
| Newton, NE | 2 |
| Abdel-Monem, MM | 2 |
| Ohno, K | 1 |
| Canellakis, ES | 1 |
| Bellantone, RA | 1 |
| Stanek, J | 1 |
| Black, J | 1 |
| Vaughan, M | 1 |
| Ganis, B | 1 |
| Pleshkewych, A | 1 |
| Wechter, RS | 1 |
| Wotring, LL | 1 |
| Townsend, LB | 1 |
| Jones, LM | 1 |
| Borysko, KZ | 1 |
| Gildersleeve, DL | 1 |
| Parker, WB | 1 |
| Kramer, DL | 1 |
| Bukin, YV | 1 |
| Hessels, J | 1 |
| Kingma, AW | 1 |
| Ferwerda, H | 1 |
| Keij, J | 1 |
| van den Berg, GA | 1 |
| Muskiet, FA | 1 |
| Nowatari, H | 1 |
| Kuroda, Y | 1 |
| Hayami, H | 1 |
| Okamoto, K | 1 |
| Ekimoto, H | 1 |
| Takahashi, K | 1 |
| Dorr, RT | 1 |
| Liddil, JD | 1 |
| Gerner, EW | 1 |
| Holm, I | 1 |
| Secrist, JA | 1 |
| Madhubala, R | 1 |
| McManis, J | 1 |
| Casero, RA | 1 |
| Russell, DH | 3 |
| Corti, A | 1 |
| Dave, C | 1 |
| Williams-Ashman, HG | 1 |
| Mihich, E | 1 |
| Schenone, A | 1 |
| Hacker, B | 1 |
| McDermott, BJ | 1 |
1 review available for putrescine and Leukemia L 1210
| Article | Year |
|---|---|
Polyamine transport in cells.
Topics: Animals; Biological Transport; Cells, Cultured; Escherichia coli; Humans; Kinetics; Leukemia L1210; | 1994 |
33 other studies available for putrescine and Leukemia L 1210
| Article | Year |
|---|---|
alpha-Methyl polyamines: metabolically stable spermidine and spermine mimics capable of supporting growth in cells depleted of polyamines.
Topics: Animals; Cell Division; Cell Line, Transformed; Colonic Neoplasms; Eflornithine; Humans; Leukemia L1 | 1992 |
Solid phase organic synthesis of polyamine derivatives and initial biological evaluation of their antitumoral activity.
Topics: Amine Oxidase (Copper-Containing); Animals; Antineoplastic Agents; Calmodulin; Cattle; Cell Survival | 1998 |
SYNTHESIS OF MUSTARDS FROM PUTRESCINE, CADAVERINE, AND 1,3-DIAMINOPROPANE.
Topics: Amines; Animals; Cadaverine; Chemistry, Pharmaceutical; Diamines; Leukemia L1210; Mice; Mustard Plan | 1963 |
Enhancement of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced cytotoxicity and DNA damage by alpha-difluoromethylornithine in L1210 leukemia cells.
Topics: Animals; Carmustine; Cell Survival; DNA, Neoplasm; Drug Synergism; Eflornithine; Kinetics; Leukemia | 1984 |
Interactions between bis(guanylhydrazones) and polyamines in isolated mitochondria.
Topics: Animals; Antineoplastic Agents; Carbanilides; Dinitrophenols; Drug Interactions; Guanidines; In Vitr | 1983 |
Spermidine requirement for cell proliferation in eukaryotic cells: structural specificity and quantitation.
Topics: Animals; Cell Division; Cell Physiological Phenomena; Eukaryotic Cells; Leukemia L1210; Mice; Ornith | 1983 |
Induction of apoptosis by excessive polyamine accumulation in ornithine decarboxylase-overproducing L1210 cells.
Topics: Animals; Apoptosis; Biogenic Polyamines; DNA, Neoplasm; Hydrogen Peroxide; Leukemia L1210; Mice; Orn | 1995 |
Polyamine-mediated regulation of S-adenosylmethionine decarboxylase expression in mammalian cells. Studies using 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine, a suicide inhibitor of the enzyme.
Topics: Adenosylmethionine Decarboxylase; Animals; Deoxyadenosines; Enzyme Precursors; Gene Expression Regul | 1993 |
Enhancement of the spermidine uptake system and lethal effects of spermidine overaccumulation in ornithine decarboxylase-overproducing L1210 cells under hyposmotic stress.
Topics: Animals; Biological Transport; Cell Division; Cell Survival; Leukemia L1210; Mice; Ornithine Decarbo | 1993 |
Stable intracellular acidification upon polyamine depletion induced by alpha-difluoromethylornithine or N1,N12-bis(ethyl)spermine in L1210 leukaemia cells.
Topics: Animals; Antineoplastic Agents; Bicarbonates; Eflornithine; Hydrogen-Ion Concentration; Leukemia L12 | 1995 |
[New aminooxy analogs of biogenic polyamines].
Topics: Animals; Cell Division; Cell Line; Cricetinae; Leukemia L1210; Putrescine; Spermidine; Spermine; Tum | 1996 |
Bis(7-amino-4-azaheptyl)dimethylsilane: a new tetramine with polyamine-like features. Effects on cell growth.
Topics: Animals; Antineoplastic Agents; Cell Division; Drug Screening Assays, Antitumor; Leukemia L1210; Neo | 1997 |
Dimethylsilane polyamines: cytostatic compounds with potentials as anticancer drugs.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; CHO Cells; Cricetinae; DNA; Drug Screening As | 1997 |
Polyamine sulfonamides with NMDA antagonist properties are potent calmodulin antagonists and cytotoxic agents.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amine Oxidase (Copper-Containing); Animals; Antineoplastic Agen | 1998 |
Effect of N8-acetylspermidine deacetylase inhibition on the growth of L1210 cells.
Topics: Amidohydrolases; Animals; Cell Division; Chromatography, High Pressure Liquid; Diamines; Drug Intera | 1999 |
Inhibitors of polyamine biosynthesis. 4. Effects of alpha-methyl-(+/-)-ornithine and methylglyoxal bis(guanylhydrazone) on growth and polyamine content of L1210 leukemic cells of mice.
Topics: Animals; Cell Division; Cells, Cultured; DNA, Neoplasm; Guanidines; Leukemia L1210; Mice; Mitoguazon | 1977 |
Determination of diamines and polyamines in tissues by high-pressure liquid chromatography.
Topics: Animals; Brain Chemistry; Cells, Cultured; Chromatography, High Pressure Liquid; Dansyl Compounds; L | 1976 |
Diacridines: bifunctional intercalators. II. The biological effects of putrescine, sperimidine and spermine diacridines on HeLa cells and on the L-1210 and P-388 leukemia cells.
Topics: Acridines; Animals; Cell Division; HeLa Cells; Leukemia L1210; Leukemia, Experimental; Mice; Protein | 1976 |
Morphological evidence for an apparent lysosomotropic activity by unsaturated putrescine analogues.
Topics: Animals; Diamines; Leukemia L1210; Lysosomes; Mice; Microscopy, Electron; Polyamines; Putrescine; St | 1990 |
An early enlargement of the putrescine pool is required for growth in L1210 mouse leukemia cells under hypoosmotic stress.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Enzyme Induction; Leukemia L1210; Mice; Or | 1991 |
Dual mechanisms of inhibition of DNA synthesis by triciribine.
Topics: Animals; Antineoplastic Agents; DNA Polymerase I; DNA Primase; DNA Replication; DNA, Neoplasm; Kinet | 1990 |
Cellular characterization of a new irreversible inhibitor of S-adenosylmethionine decarboxylase and its use in determining the relative abilities of individual polyamines to sustain growth and viability of L1210 cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cell Division; Cell Survival; Deoxyadenos | 1989 |
Microbial flora in the gastrointestinal tract abolishes cytostatic effects of alpha-difluoromethylornithine in vivo.
Topics: Animals; Biogenic Polyamines; Combined Modality Therapy; Deuterium; Dietary Carbohydrates; Digestive | 1989 |
Synthesis and antitumor activities of alkyl-1,4-butanediamine Pt(II) complexes having seven-membered ring structure.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Female; Leukemia L1210; Mice; Mice, I | 1989 |
Modulation of etoposide cytotoxicity and DNA strand scission in L1210 and 8226 cells by polyamines.
Topics: Animals; Cell Survival; DNA Topoisomerases, Type II; DNA, Neoplasm; DNA, Single-Stranded; Eflornithi | 1986 |
Regulation of ornithine decarboxylase mRNA translation by polyamines. Studies using a cell-free system and a cell line with an amplified ornithine decarboxylase gene.
Topics: Animals; Cell-Free System; Eflornithine; Gene Amplification; Leukemia L1210; Mice; Mutation; Ornithi | 1988 |
Properties of L1210 cells resistant to alpha-difluoromethylornithine.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Deoxyadenosines; Drug Resistance; Eflornithine | 1988 |
Relative abilities of bis(ethyl) derivatives of putrescine, spermidine, and spermine to regulate polyamine biosynthesis and inhibit L1210 leukemia cell growth.
Topics: Adenosylmethionine Decarboxylase; Animals; Biological Transport; Cell Division; Leukemia L1210; Mice | 1987 |
Depression of polyamine synthesis in L1210 leukemic mice during treatment with a potent antileukemic agent, 5-azacytidine.
Topics: Animals; Antineoplastic Agents; Azacitidine; Carboxy-Lyases; Cytidine; Depression, Chemical; Enzyme | 1973 |
Specific inhibition of the enzymic decarboxylation of S-adenosylmethionine by methylglyoxal bis(guanylhydrazone) and related substances.
Topics: Amidines; Animals; Brain; Carboxy-Lyases; Cell Line; Enzyme Inhibitors; Female; Glyoxal; Hydrazones; | 1974 |
Polyamines and transfer RNA-methylation in mouse leukemic cells.
Topics: Animals; Binding Sites; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Paper; Chromatogr | 1972 |
Effects of methylglyoxal-bis(guanylhydrazone) on polyamine metabolism in spleens of mice with disseminated L1210 lymphoid leukemia.
Topics: Amidines; Animals; Antineoplastic Agents; Carboxy-Lyases; Glyoxal; Hydrazones; Leukemia L1210; Male; | 1974 |
Effects of methotrexate and cytosine arabinoside on polyamine metabolism in a mouse L1210 leukemia.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Cytarabine; Leukemia L1210; Methotrexate; Mice; Mice, Inbr | 1972 |