putrescine has been researched along with Disease Models, Animal in 44 studies
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we show that extracellular spermine, one of the endogenous polyamines, exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis." | 7.77 | Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. ( Cao, H; Chu, XP; Duan, B; Hansen, J; Huang, Y; Simon, RP; Wang, YZ; Xiong, ZG; Xu, TL; Yang, T; Yu, Y; Zhu, MX, 2011) |
| " After status epilepticus induced by kainic acid (9 mg/kg, i." | 7.71 | Cerebral distribution of polyamines in kainic acid-induced models of status epilepticus and ataxia in rats. Overproduction of putrescine and histological damage. ( Camón, L; de Vera, N; Martínez, E, 2002) |
| "The aim was to investigate the involvement of polyamines in the development of cardiovascular hypertrophy in a rat angiotensin II infusion model of hypertension." | 7.69 | Role of polyamines in hypertension induced by angiotensin II. ( Hughes, AD; Ibrahim, J; Schachter, M; Sever, PS, 1995) |
| "Experimental pancreatitis is associated with activation of polyamine catabolism." | 5.37 | Association between remote organ injury and tissue polyamine homeostasis in acute experimental pancreatitis - treatment with a polyamine analogue bismethylspermine. ( Alhonen, L; Grigorenko, N; Hyvönen, MT; Jin, HT; Khomutov, AR; Lämsä, T; Nordback, I; Nordback, PH; Pörsti, I; Räty, S; Sand, J, 2011) |
| " In the survival study, a dose-response effect of ciprofloxacin on survival was observed (ciprofloxacin: 10 mg/kg, 10%; 50 mg/kg, 26%; and 100 mg/kg, 35%) with the results in the 100-mg/kg-treated group being significant when compared with the 5% survival rate in saline-treated controls (P < ." | 5.30 | The beneficial effects of ciprofloxacin on survival and hepatic regenerative activity in a rat model of fulminant hepatic failure. ( Assy, N; Gauthier, T; Kaita, KD; Meyers, AF; Minuk, GY; Zhang, M, 1998) |
| " Previous studies from our laboratory demonstrated that spermine oxidase (SMOX, a member of the polyamine oxidase family) inhibition using MDL 72527 reduced neurodegeneration in models of retinal excitotoxicity and diabetic retinopathy." | 4.12 | Pharmacological Inhibition of Spermine Oxidase Suppresses Excitotoxicity Induced Neuroinflammation in Mouse Retina. ( Alfarhan, M; Liu, F; Narayanan, SP; Pichavaram, P; Shan, S; Somanath, PR, 2022) |
| " Here, we show that extracellular spermine, one of the endogenous polyamines, exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis." | 3.77 | Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. ( Cao, H; Chu, XP; Duan, B; Hansen, J; Huang, Y; Simon, RP; Wang, YZ; Xiong, ZG; Xu, TL; Yang, T; Yu, Y; Zhu, MX, 2011) |
| " Further, ETBF-induced colitis in C57BL/6 mice is associated with increased SMO expression and treatment of mice with an inhibitor of polyamine catabolism, N(1),N(4)-bis(2,3-butandienyl)-1,4-butanediamine (MDL 72527), significantly reduces ETBF-induced chronic inflammation and proliferation." | 3.77 | Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis. ( Casero, RA; Destefano Shields, CE; Goodwin, AC; Hacker-Prietz, A; Huso, DL; Murray-Stewart, TR; Rabizadeh, S; Sears, CL; Woster, PM; Wu, S; Wu, X, 2011) |
| "Putrescine, a polyamine present at high concentrations in the mammalian brain, was suggested to play a role in the modulation of depression." | 3.73 | Putrescine produces antidepressant-like effects in the forced swimming test and in the tail suspension test in mice. ( Rodrigues, AL; Santos, AR; Zomkowski, AD, 2006) |
| " After status epilepticus induced by kainic acid (9 mg/kg, i." | 3.71 | Cerebral distribution of polyamines in kainic acid-induced models of status epilepticus and ataxia in rats. Overproduction of putrescine and histological damage. ( Camón, L; de Vera, N; Martínez, E, 2002) |
| "The aim was to investigate the involvement of polyamines in the development of cardiovascular hypertrophy in a rat angiotensin II infusion model of hypertension." | 3.69 | Role of polyamines in hypertension induced by angiotensin II. ( Hughes, AD; Ibrahim, J; Schachter, M; Sever, PS, 1995) |
| "Cerebral ischemia causes activation of ornithine decarboxylase (ODC) gene and subsequent accumulation of putrescine, which might either directly or indirectly affect the outcome of cerebral infarct." | 3.69 | Transgenic rats as models for studying the role of ornithine decarboxylase expression in permanent middle cerebral artery occlusion. ( Alhonen, LI; Gröhn, OH; Jänne, J; Järvinen, A; Kauppinen, RA; Lukkarinen, J; Sinervirta, R, 1997) |
| "It has been suggested that the induction of ornithine decarboxylase (ODC) activity during pregnancy might contribute to the low ureagenic flux that enables the pregnant mother to spare nitrogen and support growth." | 3.68 | Ornithine decarboxylase activity and urea in liver of late-pregnant rats. Effect of streptozotocin-induced diabetes. ( Pastor-Anglada, M; Poveda, B; Soler, C; Soley, M, 1993) |
| "Age and sex are risk factors of Alzheimer's disease (AD)." | 1.48 | Sex- and age-specific modulation of brain GABA levels in a mouse model of Alzheimer's disease. ( Alia, A; Hartlage-Rübsamen, M; Höfling, C; Matysik, J; Roy, U; Roβner, S; Stute, L, 2018) |
| "Experimental pancreatitis is associated with activation of polyamine catabolism." | 1.37 | Association between remote organ injury and tissue polyamine homeostasis in acute experimental pancreatitis - treatment with a polyamine analogue bismethylspermine. ( Alhonen, L; Grigorenko, N; Hyvönen, MT; Jin, HT; Khomutov, AR; Lämsä, T; Nordback, I; Nordback, PH; Pörsti, I; Räty, S; Sand, J, 2011) |
| " In the survival study, a dose-response effect of ciprofloxacin on survival was observed (ciprofloxacin: 10 mg/kg, 10%; 50 mg/kg, 26%; and 100 mg/kg, 35%) with the results in the 100-mg/kg-treated group being significant when compared with the 5% survival rate in saline-treated controls (P < ." | 1.30 | The beneficial effects of ciprofloxacin on survival and hepatic regenerative activity in a rat model of fulminant hepatic failure. ( Assy, N; Gauthier, T; Kaita, KD; Meyers, AF; Minuk, GY; Zhang, M, 1998) |
| "Putrescine efflux also was altered by hypoxic exposure; T1/2 for loss of diamine from a slowly effluxing pool was increased from 60." | 1.28 | Mechanisms of lung polyamine accumulation in chronic hypoxic pulmonary hypertension. ( Gillespie, MN; Kostenbauder, HB; Olson, JW; Shiao, RT, 1990) |
| "In experimental cardiac hypertrophy induced by aortic constriction of rats, the hypertrophy was established after 5-7 days." | 1.26 | Biochemical aspects of experimental cardiac hypertrophy. ( Matsushita, S, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (9.09) | 18.7374 |
| 1990's | 8 (18.18) | 18.2507 |
| 2000's | 13 (29.55) | 29.6817 |
| 2010's | 14 (31.82) | 24.3611 |
| 2020's | 5 (11.36) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Alfarhan, M | 1 |
| Liu, F | 1 |
| Shan, S | 1 |
| Pichavaram, P | 1 |
| Somanath, PR | 1 |
| Narayanan, SP | 2 |
| Kovács, Z | 1 |
| Skatchkov, SN | 1 |
| Szabó, Z | 1 |
| Qahtan, S | 1 |
| Méndez-González, MP | 1 |
| Malpica-Nieves, CJ | 1 |
| Eaton, MJ | 1 |
| Kardos, J | 1 |
| Héja, L | 1 |
| Grosheva, I | 1 |
| Zheng, D | 1 |
| Levy, M | 1 |
| Polansky, O | 1 |
| Lichtenstein, A | 1 |
| Golani, O | 1 |
| Dori-Bachash, M | 1 |
| Moresi, C | 1 |
| Shapiro, H | 1 |
| Del Mare-Roumani, S | 1 |
| Valdes-Mas, R | 1 |
| He, Y | 1 |
| Karbi, H | 1 |
| Chen, M | 1 |
| Harmelin, A | 1 |
| Straussman, R | 1 |
| Yissachar, N | 1 |
| Elinav, E | 1 |
| Geiger, B | 1 |
| Zhang, T | 1 |
| Hu, L | 1 |
| Tang, JF | 1 |
| Xu, H | 1 |
| Tian, K | 1 |
| Wu, MN | 1 |
| Huang, SY | 1 |
| Du, YM | 1 |
| Zhou, P | 1 |
| Lu, RJ | 1 |
| He, S | 1 |
| Xu, JM | 1 |
| Si, JJ | 1 |
| Li, J | 1 |
| Chen, DL | 1 |
| Ran, JH | 1 |
| Roy, U | 1 |
| Stute, L | 1 |
| Höfling, C | 1 |
| Hartlage-Rübsamen, M | 1 |
| Matysik, J | 1 |
| Roβner, S | 1 |
| Alia, A | 1 |
| McKenna, J | 1 |
| Kapfhamer, D | 1 |
| Kinchen, JM | 1 |
| Wasek, B | 1 |
| Dunworth, M | 1 |
| Murray-Stewart, T | 1 |
| Bottiglieri, T | 1 |
| Casero, RA | 2 |
| Gambello, MJ | 1 |
| Ramani, D | 1 |
| De Bandt, JP | 1 |
| Cynober, L | 1 |
| Jo, S | 1 |
| Yarishkin, O | 1 |
| Hwang, YJ | 1 |
| Chun, YE | 1 |
| Park, M | 1 |
| Woo, DH | 1 |
| Bae, JY | 1 |
| Kim, T | 1 |
| Lee, J | 1 |
| Chun, H | 1 |
| Park, HJ | 1 |
| Lee, DY | 1 |
| Hong, J | 1 |
| Kim, HY | 1 |
| Oh, SJ | 1 |
| Park, SJ | 1 |
| Lee, H | 1 |
| Yoon, BE | 1 |
| Kim, Y | 1 |
| Jeong, Y | 1 |
| Shim, I | 1 |
| Bae, YC | 1 |
| Cho, J | 1 |
| Kowall, NW | 1 |
| Ryu, H | 1 |
| Hwang, E | 1 |
| Kim, D | 1 |
| Lee, CJ | 1 |
| Pan, P | 1 |
| Skaer, CW | 1 |
| Wang, HT | 1 |
| Stirdivant, SM | 1 |
| Young, MR | 1 |
| Oshima, K | 1 |
| Stoner, GD | 1 |
| Lechner, JF | 1 |
| Huang, YW | 1 |
| Wang, LS | 1 |
| Patel, C | 1 |
| Xu, Z | 1 |
| Shosha, E | 1 |
| Xing, J | 1 |
| Lucas, R | 1 |
| Caldwell, RW | 1 |
| Caldwell, RB | 1 |
| Kanika, ND | 1 |
| Tar, M | 1 |
| Tong, Y | 1 |
| Kuppam, DS | 1 |
| Melman, A | 1 |
| Davies, KP | 1 |
| Basu, HS | 1 |
| Thompson, TA | 1 |
| Church, DR | 1 |
| Clower, CC | 1 |
| Mehraein-Ghomi, F | 1 |
| Amlong, CA | 1 |
| Martin, CT | 1 |
| Woster, PM | 2 |
| Lindstrom, MJ | 1 |
| Wilding, G | 1 |
| Zahedi, K | 1 |
| Barone, S | 1 |
| Kramer, DL | 1 |
| Amlal, H | 1 |
| Alhonen, L | 3 |
| Jänne, J | 3 |
| Porter, CW | 1 |
| Soleimani, M | 1 |
| Olenyik, T | 1 |
| Gilroy, C | 1 |
| Ullman, B | 1 |
| Tallant, MD | 1 |
| Duan, M | 1 |
| Freeman, GA | 1 |
| Ferris, RG | 1 |
| Edelstein, MP | 1 |
| Kazmierski, WM | 1 |
| Wheelan, PJ | 1 |
| Duan, B | 1 |
| Wang, YZ | 1 |
| Yang, T | 1 |
| Chu, XP | 1 |
| Yu, Y | 1 |
| Huang, Y | 1 |
| Cao, H | 1 |
| Hansen, J | 1 |
| Simon, RP | 1 |
| Zhu, MX | 1 |
| Xiong, ZG | 1 |
| Xu, TL | 1 |
| Goodwin, AC | 1 |
| Destefano Shields, CE | 1 |
| Wu, S | 1 |
| Huso, DL | 1 |
| Wu, X | 1 |
| Murray-Stewart, TR | 1 |
| Hacker-Prietz, A | 1 |
| Rabizadeh, S | 1 |
| Sears, CL | 1 |
| Jin, HT | 1 |
| Lämsä, T | 1 |
| Nordback, PH | 1 |
| Hyvönen, MT | 1 |
| Grigorenko, N | 1 |
| Khomutov, AR | 1 |
| Nordback, I | 1 |
| Räty, S | 1 |
| Pörsti, I | 1 |
| Sand, J | 1 |
| Tao, Y | 1 |
| Liu, XJ | 1 |
| de Vera, N | 2 |
| Camón, L | 2 |
| Martínez, E | 2 |
| Poduslo, JF | 2 |
| Wengenack, TM | 1 |
| Curran, GL | 1 |
| Wisniewski, T | 1 |
| Sigurdsson, EM | 1 |
| Macura, SI | 1 |
| Borowski, BJ | 1 |
| Jack, CR | 1 |
| Wood, PL | 1 |
| Khan, MA | 1 |
| Kulow, SR | 1 |
| Mahmood, SA | 1 |
| Moskal, JR | 1 |
| Zomkowski, AD | 1 |
| Santos, AR | 1 |
| Rodrigues, AL | 1 |
| Tzirogiannis, KN | 1 |
| Papadimas, GK | 1 |
| Kondyli, VG | 1 |
| Kourentzi, KT | 1 |
| Demonakou, MD | 1 |
| Kyriakou, LG | 1 |
| Mykoniatis, MG | 1 |
| Hereti, RI | 1 |
| Panoutsopoulos, GI | 1 |
| Ignatenko, NA | 1 |
| Besselsen, DG | 1 |
| Roy, UK | 1 |
| Stringer, DE | 1 |
| Blohm-Mangone, KA | 1 |
| Padilla-Torres, JL | 1 |
| Guillen-R, JM | 1 |
| Gerner, EW | 1 |
| Han, L | 1 |
| Xu, C | 1 |
| Guo, Y | 1 |
| Li, H | 1 |
| Jiang, C | 1 |
| Zhao, Y | 1 |
| Lowe, NJ | 1 |
| Chalet, M | 1 |
| Breeding, J | 1 |
| Kean, C | 1 |
| Russell, DH | 1 |
| Ibrahim, J | 1 |
| Schachter, M | 1 |
| Hughes, AD | 1 |
| Sever, PS | 1 |
| Poveda, B | 1 |
| Soler, C | 1 |
| Soley, M | 1 |
| Pastor-Anglada, M | 1 |
| Lukkarinen, J | 1 |
| Gröhn, OH | 1 |
| Sinervirta, R | 2 |
| Järvinen, A | 1 |
| Kauppinen, RA | 1 |
| Alhonen, LI | 1 |
| Kaita, KD | 1 |
| Assy, N | 1 |
| Gauthier, T | 1 |
| Zhang, M | 1 |
| Meyers, AF | 1 |
| Minuk, GY | 1 |
| Mutomba, MC | 1 |
| Li, F | 1 |
| Gottesdiener, KM | 1 |
| Wang, CC | 1 |
| Reinholz, MM | 1 |
| Merkle, CM | 1 |
| Parkkinen, JJ | 1 |
| Keinanen, T | 1 |
| Herzig, KH | 1 |
| Lopatin, AN | 1 |
| Shantz, LM | 1 |
| Mackintosh, CA | 1 |
| Nichols, CG | 1 |
| Pegg, AE | 1 |
| Yoneda, Y | 1 |
| Kawajiri, S | 1 |
| Sugimura, M | 1 |
| Osanai, K | 1 |
| Kito, F | 1 |
| Ota, E | 1 |
| Mimura, T | 1 |
| Matsushita, S | 1 |
| Thomas, TJ | 1 |
| Gunnia, UB | 1 |
| Thomas, T | 1 |
| Shiao, RT | 1 |
| Kostenbauder, HB | 1 |
| Olson, JW | 1 |
| Gillespie, MN | 1 |
| Nemery, B | 1 |
| Domschke, S | 1 |
| Domschke, W | 1 |
2 reviews available for putrescine and Disease Models, Animal
| Article | Year |
|---|---|
Aliphatic polyamines in physiology and diseases.
Topics: Agmatine; Animals; Disease Models, Animal; Humans; Neoplasms; Ornithine; Putrescine; Spermidine; Spe | 2014 |
Polyamines and the liver.
Topics: Animals; Carboxy-Lyases; Disease Models, Animal; DNA; Liver; Liver Regeneration; Polyamines; Putresc | 1972 |
42 other studies available for putrescine and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Pharmacological Inhibition of Spermine Oxidase Suppresses Excitotoxicity Induced Neuroinflammation in Mouse Retina.
Topics: Animals; Antioxidants; Diabetic Retinopathy; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; | 2022 |
Putrescine Intensifies Glu/GABA Exchange Mechanism and Promotes Early Termination of Seizures.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; gamma-Aminobutyric Acid; P | 2022 |
High-Throughput Screen Identifies Host and Microbiota Regulators of Intestinal Barrier Function.
Topics: Animals; Caco-2 Cells; Citrobacter rodentium; Colitis; Colon; Dextran Sulfate; Disease Models, Anima | 2020 |
Metformin Inhibits the Urea Cycle and Reduces Putrescine Generation in Colorectal Cancer Cell Lines.
Topics: Animals; Biomarkers; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colorectal Neopla | 2021 |
Sex- and age-specific modulation of brain GABA levels in a mouse model of Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Amyloidogenic Proteins; Animals; Astrocytes; Brain; Disease Models, Animal | 2018 |
Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex.
Topics: Animals; Brain; Cystathionine; Cystathionine beta-Synthase; Disease Models, Animal; DNA Methylation; | 2018 |
GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Astrocytes; | 2014 |
Black raspberries suppress colonic adenoma development in ApcMin/+ mice: relation to metabolite profiles.
Topics: Adenoma; Adenomatous Polyposis Coli Protein; alpha-Linolenic Acid; Animals; Colorectal Neoplasms; Di | 2015 |
Treatment with polyamine oxidase inhibitor reduces microglial activation and limits vascular injury in ischemic retinopathy.
Topics: Animals; Cell Death; Cell Differentiation; Cells, Cultured; Culture Media, Conditioned; Disease Mode | 2016 |
The mechanism of opiorphin-induced experimental priapism in rats involves activation of the polyamine synthetic pathway.
Topics: Anemia, Sickle Cell; Animals; Arginase; Diamines; Disease Models, Animal; Male; Mice; Oligopeptides; | 2009 |
A small molecule polyamine oxidase inhibitor blocks androgen-induced oxidative stress and delays prostate cancer progression in the transgenic adenocarcinoma of the mouse prostate model.
Topics: Acetyltransferases; Adenocarcinoma; Androgens; Animals; Cell Line, Tumor; Disease Models, Animal; Di | 2009 |
The role of spermidine/spermine N1-acetyltransferase in endotoxin-induced acute kidney injury.
Topics: Acetyltransferases; Acute Disease; Animals; Creatinine; Disease Models, Animal; Enzyme Inhibitors; G | 2010 |
Oral putrescine restores virulence of ornithine decarboxylase-deficient Leishmania donovani in mice.
Topics: Administration, Oral; Animals; Disease Models, Animal; Eflornithine; Enzyme Inhibitors; Female; Leis | 2011 |
Synthesis and evaluation of 2-phenyl-1,4-butanediamine-based CCR5 antagonists for the treatment of HIV-1.
Topics: Animals; Anti-HIV Agents; CCR5 Receptor Antagonists; Cell Line; Disease Models, Animal; HIV Infectio | 2011 |
Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis.
Topics: Acid Sensing Ion Channels; Acidosis; Amino Acid Transport System y+; Animals; Biophysics; Brain Inju | 2011 |
Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis.
Topics: Acetyltransferases; Animals; Bacterial Toxins; Bacteroides fragilis; Cell Line; Cell Proliferation; | 2011 |
Association between remote organ injury and tissue polyamine homeostasis in acute experimental pancreatitis - treatment with a polyamine analogue bismethylspermine.
Topics: Acetyltransferases; Animals; Creatinine; Disease Models, Animal; Dose-Response Relationship, Drug; K | 2011 |
Deficiency of ovarian ornithine decarboxylase contributes to aging-related egg aneuploidy in mice.
Topics: Aging; Aneuploidy; Animals; Disease Models, Animal; Female; Male; Meiosis; Mice; Mice, Inbred C57BL; | 2013 |
Cerebral distribution of polyamines in kainic acid-induced models of status epilepticus and ataxia in rats. Overproduction of putrescine and histological damage.
Topics: Analysis of Variance; Animals; Ataxia; Biogenic Polyamines; Brain; Disease Models, Animal; Dose-Resp | 2002 |
Molecular targeting of Alzheimer's amyloid plaques for contrast-enhanced magnetic resonance imaging.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; B | 2002 |
Neurotoxicity of reactive aldehydes: the concept of "aldehyde load" as demonstrated by neuroprotection with hydroxylamines.
Topics: Aldehydes; Animals; Behavior, Animal; Cell Line; Cyclic N-Oxides; Disease Models, Animal; Dose-Respo | 2006 |
Putrescine produces antidepressant-like effects in the forced swimming test and in the tail suspension test in mice.
Topics: Agmatine; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Female; Imipramine; Im | 2006 |
Peliosis hepatis: microscopic and macroscopic type, time pattern, and correlation with liver cell apoptosis in a model of toxic liver injury.
Topics: Animals; Apoptosis; Cadmium; Disease Models, Animal; Hepatocytes; In Situ Nick-End Labeling; Liver; | 2006 |
Dietary putrescine reduces the intestinal anticarcinogenic activity of sulindac in a murine model of familial adenomatous polyposis.
Topics: Adenomatous Polyposis Coli; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Cycloo | 2006 |
Polyamine metabolism in rat myocardial ischemia-reperfusion injury.
Topics: Acetyltransferases; Animals; Coronary Vessels; Disease Models, Animal; Heart Rate; Myocardial Reperf | 2009 |
Psoriasiform dermatosis in a rhesus monkey. Epidermal labeling indexes, polyamines, and histopathologic findings.
Topics: Animals; Disease Models, Animal; DNA; Humans; Infant, Newborn; Macaca mulatta; Psoriasis; Putrescine | 1982 |
Role of polyamines in hypertension induced by angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Cardiomegaly; Disease Models, Animal; Heart Ventricles; Hypertension | 1995 |
Ornithine decarboxylase activity and urea in liver of late-pregnant rats. Effect of streptozotocin-induced diabetes.
Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Body Weight; Diabetes Mellitus, Experimental; Disease M | 1993 |
Transgenic rats as models for studying the role of ornithine decarboxylase expression in permanent middle cerebral artery occlusion.
Topics: Animals; Animals, Genetically Modified; Arterial Occlusive Diseases; Brain Ischemia; Cell Death; Dis | 1997 |
The beneficial effects of ciprofloxacin on survival and hepatic regenerative activity in a rat model of fulminant hepatic failure.
Topics: Alanine Transaminase; Animals; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; DNA; Im | 1998 |
A Trypanosoma brucei bloodstream form mutant deficient in ornithine decarboxylase can protect against wild-type infection in mice.
Topics: Africa South of the Sahara; Animals; Antibodies, Monoclonal; Blotting, Western; Disease Models, Anim | 1999 |
Therapeutic benefits of putrescine-modified catalase in a transgenic mouse model of familial amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Blood-Brain Barrier; Buffers; Catalase; Diseas | 1999 |
Activation of polyamine catabolism in transgenic rats induces acute pancreatitis.
Topics: Acetyltransferases; Acute Disease; Animals; Animals, Genetically Modified; Disease Models, Animal; E | 2000 |
Modulation of potassium channels in the hearts of transgenic and mutant mice with altered polyamine biosynthesis.
Topics: Animals; Cadaverine; Cells, Cultured; Disease Models, Animal; Hypophosphatemia, Familial; Ion Transp | 2000 |
Synthesis of diaminobutane derivatives as potent Ca(2+)-permeable AMPA receptor antagonists.
Topics: Animals; Calcium; Disease Models, Animal; Gerbillinae; Ischemia; Neuroprotective Agents; Putrescine; | 2001 |
Polyamine metabolism and glutamate receptor agonists-mediated excitotoxicity in the rat brain.
Topics: Animals; Biogenic Polyamines; Biomarkers; Body Weight; Brain; Disease Models, Animal; Epilepsy; Exci | 2001 |
Biochemical aspects of experimental cardiac hypertrophy.
Topics: Adenosine Triphosphatases; Animals; Cardiomegaly; Disease Models, Animal; DNA; Myocardial Contractio | 1976 |
Reversal of the abnormal development of T cell subpopulations in the thymus of autoimmune MRL-lpr/lpr mice by a polyamine biosynthesis inhibitor.
Topics: Animals; Autoimmunity; CD4-CD8 Ratio; Disease Models, Animal; Eflornithine; Lupus Erythematosus, Sys | 1992 |
Mechanisms of lung polyamine accumulation in chronic hypoxic pulmonary hypertension.
Topics: Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Liv | 1990 |
Respiratory and non-respiratory lung function indices during the development and resolution of O,S,S-trimethyl phosphorodithioate-induced lung damage in the rat. A chemical model of adult respiratory distress syndrome.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Female; Humans; Infant, Newborn; Lung Diseases; | 1987 |