putrescine has been researched along with Colonic Neoplasms in 53 studies
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Further, ETBF-induced colitis in C57BL/6 mice is associated with increased SMO expression and treatment of mice with an inhibitor of polyamine catabolism, N(1),N(4)-bis(2,3-butandienyl)-1,4-butanediamine (MDL 72527), significantly reduces ETBF-induced chronic inflammation and proliferation." | 3.77 | Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis. ( Casero, RA; Destefano Shields, CE; Goodwin, AC; Hacker-Prietz, A; Huso, DL; Murray-Stewart, TR; Rabizadeh, S; Sears, CL; Woster, PM; Wu, S; Wu, X, 2011) |
| " The present results show that multidrug-resistant human colon adenocarcinoma cells (LoVo) are significantly more sensitive than corresponding wild-type cells to hydrogen peroxide and aldehydes, the products of bovine serum amine oxidase (BSAO)-catalyzed oxidation of spermine." | 3.73 | Sensitization of human colon adenocarcinoma cells (LoVo) to reactive oxygen species by a lysosomotropic compound. ( Agostinelli, E; Arancia, G; Belli, F; Condello, M; Seiler, N; Vedova, LD, 2006) |
| "In total, 2502 colorectal cancer cases and 2538 age-(5-year interval) and sex-matched controls were recruited from July 2010 to April 2019." | 1.56 | Dietary Polyamines Intake and Risk of Colorectal Cancer: A Case-Control Study. ( Abulimiti, A; Chen, YM; Fang, YJ; Feng, XL; Huang, CY; Li, L; Liu, KY; Yang, X; Zhang, CX; Zhang, X, 2020) |
| "Putrescine treatment (100pmol/L) raised MAT2A mRNA level to 4." | 1.39 | Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer. ( Giordano, P; Lu, SC; Mato, JM; Ryoo, M; Skay, A; Tomasi, I; Tomasi, ML, 2013) |
| "Thus, HGC-27 human gastric cancer cells and DLD-1 human colonic adenocarcinoma cells were evaluated." | 1.35 | Effects of Lactobacillus rhamnosus GG on proliferation and polyamine metabolism in HGC-27 human gastric and DLD-1 colonic cancer cell lines. ( Cavallini, A; Linsalata, M; Messa, C; Orlando, A; Russo, F, 2009) |
| "When human colon cancer cells were exposed to 7beta-OHsitosterol and to 7beta-OHcholesterol at concentrations inhibiting growth by the same degree, both compounds caused a reduction of polyamine biosynthetic enzyme activity, of the polyamine pools, and an increase of N1-acetylspermidine concentration indicating the enhancement of polyamine catabolism." | 1.33 | Perturbation of polyamine metabolism and its relation to cell death in human colon cancer cells treated by 7beta-hydroxycholesterol and 7beta-hydroxysitosterol. ( Aoudé-Werner, D; Geoffroy, P; Gossé, F; Marchioni, E; Miesch, M; Raul, F; Roussi, S; Zhang, X, 2006) |
| "The aspirin effects were apparently unrelated to prostaglandin biosynthesis inhibition, since although these cells were found to express high levels of cyclooxygenase 1 (COX-1) and low levels of COX-2 proteins, they did not produce any measurable net amounts of prostaglandins, based on both utilization of radiolabelled arachidonic acid and the radioimmunoassay of prostaglandins E2 and F2 alpha." | 1.32 | Prostaglandin-independent effects of aspirin on cell cycle and putrescine synthesis in human colon carcinoma cells. ( Andriamihaja, M; Blachier, F; Camous, S; Charpigny, G; Eklou-Kalonji, E; Mayeur, C; Reinaud, P; Robert, V, 2003) |
| "Deoxycholic acid (DCA) has long been implicated as tumour-promoting agent in the colon." | 1.31 | Low-dose deoxycholic acid stimulates putrescine uptake in colon cancer cells (Caco-2). ( Gilani, S; Milovic, V; Murphy, GM; Odera, G; Stein, J, 2000) |
| "In contrast to other cells of the body, colon cancer cells are exposed to high putrescine concentrations from the lumen." | 1.30 | S-adenosylmethionine decarboxylase activity and utilization of exogenous putrescine are enhanced in colon cancer cells stimulated to grow by EGF. ( Caspary, WF; Fares, FA; Lerner, A; Milovic, V; Stein, J; Turhanowa, L, 1998) |
| "Putrescine was taken up by HT-29 cells, leading to the production of a modest amount of spermidine." | 1.29 | Metabolism of L-arginine through polyamine and nitric oxide synthase pathways in proliferative or differentiated human colon carcinoma cells. ( Blachier, F; Duée, PH; M'Rabet-Touil, H; Robert, V; Selamnia, M, 1995) |
| "once weekly for 20 wk to induce colon cancer." | 1.28 | Reduced growth rate of dimethylhydrazine-induced colon tumors in rats. ( Koike, T; Shibusawa, M; Tsunoda, A; Tsunoda, Y; Yasuda, N, 1992) |
| "A human colon cancer cell line Hce-8693 was heterotransplanted in nude mice." | 1.28 | [Inhibition by polyamine biosynthesis inhibitor DFMO of the growth of transplanted human colon cancer in nude mice]. ( Wang, M, 1991) |
| "[3H]putrescine was taken up more readily by the basolateral than by the apical side of the cells." | 1.28 | Putrescine uptake and release by colon cancer cells. ( Johnson, LR; McCormack, SA, 1989) |
| "Polyamine content of colorectal cancers was independent of tumour site, Dukes' stage, histological grade and the presence of palpable liver metastases at laparotomy." | 1.27 | Polyamines in colorectal cancer. ( Kingsnorth, AN; Lumsden, AB; Wallace, HM, 1984) |
| "The presence of GR in human colon cancers has been previously reported." | 1.27 | Polyamine levels and gastrin receptors in colon cancers. ( Barranco, SC; Saydjari, R; Singh, P; Thompson, JC; Townsend, CM; Upp, JR, 1988) |
| "RBC putrescine levels were significantly increased at a tumor weight of 12." | 1.27 | Relationship of erythrocyte polyamine levels and growth rate of transplantable tumors in rats. ( Grossie, VB; Martin, RG; Nishioka, K; Ota, DM, 1986) |
| "The development of human tumors is accompanied very often by tumor-associated phenomena such as production of tumor-derived substances, production of certian substances in response to the tumor or immunological reactions." | 1.26 | Biological markers of human tumors and monitoring of cancer treatment. ( Nissen, E; Tanneberger, S; Ziegenbein, R, 1979) |
| "All 6 patients with localized malignant tumors had elevated urinary polyamine levels." | 1.25 | Urinary polyamine levels in human cancer. ( Kessler, GF; Lipton, A; Sheehan, LM, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (26.42) | 18.7374 |
| 1990's | 20 (37.74) | 18.2507 |
| 2000's | 13 (24.53) | 29.6817 |
| 2010's | 5 (9.43) | 24.3611 |
| 2020's | 1 (1.89) | 2.80 |
| Authors | Studies |
|---|---|
| Lakanen, JR | 1 |
| Coward, JK | 1 |
| Pegg, AE | 1 |
| Huang, CY | 1 |
| Fang, YJ | 1 |
| Abulimiti, A | 1 |
| Yang, X | 1 |
| Li, L | 1 |
| Liu, KY | 1 |
| Zhang, X | 2 |
| Feng, XL | 1 |
| Chen, YM | 1 |
| Zhang, CX | 1 |
| Tomasi, ML | 1 |
| Ryoo, M | 1 |
| Skay, A | 1 |
| Tomasi, I | 1 |
| Giordano, P | 1 |
| Mato, JM | 1 |
| Lu, SC | 1 |
| Orlando, A | 1 |
| Messa, C | 1 |
| Linsalata, M | 2 |
| Cavallini, A | 2 |
| Russo, F | 2 |
| Uemura, T | 1 |
| Stringer, DE | 1 |
| Blohm-Mangone, KA | 1 |
| Gerner, EW | 4 |
| Blachier, F | 4 |
| Davila, AM | 1 |
| Benamouzig, R | 1 |
| Tome, D | 1 |
| Goodwin, AC | 1 |
| Destefano Shields, CE | 1 |
| Wu, S | 1 |
| Huso, DL | 1 |
| Wu, X | 1 |
| Murray-Stewart, TR | 1 |
| Hacker-Prietz, A | 1 |
| Rabizadeh, S | 1 |
| Woster, PM | 1 |
| Sears, CL | 1 |
| Casero, RA | 3 |
| Çoker, A | 1 |
| Arısan, ED | 1 |
| Palavan-Ünsal, N | 1 |
| Duranton, B | 3 |
| Holl, V | 1 |
| Schneider, Y | 1 |
| Carnesecchi, S | 1 |
| Gossé, F | 6 |
| Raul, F | 6 |
| Seiler, N | 3 |
| Hudson, EA | 1 |
| Howells, LM | 1 |
| Gallacher-Horley, B | 1 |
| Fox, LH | 1 |
| Gescher, A | 1 |
| Manson, MM | 1 |
| Milovic, V | 4 |
| Turchanowa, L | 1 |
| Eklou-Kalonji, E | 1 |
| Andriamihaja, M | 1 |
| Reinaud, P | 1 |
| Mayeur, C | 2 |
| Camous, S | 1 |
| Robert, V | 2 |
| Charpigny, G | 1 |
| Babbar, N | 1 |
| Ignatenko, NA | 2 |
| Mouillé, B | 1 |
| Delpal, S | 1 |
| Roussi, S | 2 |
| Guyot, S | 1 |
| Schoenfelder, A | 1 |
| Mann, A | 1 |
| Bergerat, JP | 1 |
| Agostinelli, E | 1 |
| Vedova, LD | 1 |
| Belli, F | 1 |
| Condello, M | 1 |
| Arancia, G | 1 |
| Aoudé-Werner, D | 1 |
| Geoffroy, P | 1 |
| Miesch, M | 1 |
| Marchioni, E | 1 |
| Maldonado-Celisa, ME | 1 |
| Roussia, S | 1 |
| Foltzer-Jourdainne, C | 1 |
| Lobstein, A | 1 |
| Habold, C | 1 |
| Roessner, A | 1 |
| Schneider-Stock, R | 1 |
| Kingsnorth, AN | 1 |
| Lumsden, AB | 1 |
| Wallace, HM | 1 |
| Desser, H | 1 |
| Lutz, D | 1 |
| Krieger, O | 1 |
| Stierer, M | 1 |
| Selamnia, M | 1 |
| M'Rabet-Touil, H | 1 |
| Duée, PH | 1 |
| Igarashi, K | 1 |
| Koga, K | 1 |
| He, Y | 1 |
| Shimogori, T | 1 |
| Ekimoto, H | 1 |
| Kashiwagi, K | 1 |
| Shirahata, A | 1 |
| Deubner, C | 1 |
| Zeuzem, S | 1 |
| Piiper, A | 1 |
| Caspary, WF | 2 |
| Stein, J | 3 |
| McGarrity, TJ | 1 |
| Peiffer, LP | 1 |
| Berloco, P | 1 |
| Di Leo, A | 1 |
| Moreno, A | 1 |
| Arús, C | 1 |
| Löser, C | 2 |
| Starp, F | 1 |
| Fölsch, UR | 2 |
| Nsi-Emvo, E | 1 |
| Schleiffer, R | 2 |
| Galluser, M | 1 |
| Meyskens, FL | 1 |
| Emerson, S | 1 |
| Pelot, D | 1 |
| Durbin, T | 1 |
| Doyle, K | 1 |
| Lagerberg, W | 1 |
| Turhanowa, L | 1 |
| Fares, FA | 1 |
| Lerner, A | 1 |
| Olaya, J | 1 |
| Neopikhanov, V | 1 |
| Uribe, A | 1 |
| Odera, G | 1 |
| Gilani, S | 1 |
| Murphy, GM | 1 |
| Hasselmann, M | 1 |
| Lipton, A | 1 |
| Sheehan, LM | 1 |
| Kessler, GF | 1 |
| Tanneberger, S | 1 |
| Nissen, E | 1 |
| Ziegenbein, R | 1 |
| Nishioka, K | 5 |
| Romsdahl, MM | 3 |
| McMurtrey, MJ | 1 |
| Tsunoda, A | 2 |
| Shibusawa, M | 2 |
| Tsunoda, Y | 1 |
| Yasuda, N | 2 |
| Koike, T | 2 |
| Wang, M | 1 |
| Tatsuta, M | 1 |
| Iishi, H | 1 |
| Baba, M | 1 |
| Ichii, M | 1 |
| Nakaizumi, A | 1 |
| Uehara, H | 1 |
| Taniguchi, H | 1 |
| Yoshizawa, H | 1 |
| Tsuno, K | 1 |
| Takeda, M | 1 |
| Halline, AG | 2 |
| Dudeja, PK | 2 |
| Jacoby, RF | 1 |
| Llor, X | 1 |
| Teng, BB | 1 |
| Chowdhury, LN | 1 |
| Davidson, NO | 1 |
| Brasitus, TA | 2 |
| Paprotny, C | 1 |
| Creutzfeldt, W | 1 |
| Bowlin, TL | 1 |
| Rosenberger, A | 1 |
| Stemerick, D | 1 |
| Edwards, ML | 1 |
| Celano, P | 1 |
| Berchtold, CM | 1 |
| Giardiello, FM | 1 |
| McCormack, SA | 1 |
| Johnson, LR | 1 |
| Lashner, BA | 1 |
| Ota, DM | 2 |
| Grossie, B | 1 |
| Dixon, D | 1 |
| Upp, JR | 1 |
| Saydjari, R | 1 |
| Townsend, CM | 1 |
| Singh, P | 1 |
| Barranco, SC | 1 |
| Thompson, JC | 1 |
| Grossie, VB | 1 |
| Martin, RG | 1 |
| Thompson, JS | 1 |
| Edney, JA | 1 |
| Laughlin, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| To Evaluate the Performance of a Urine Spermine Measuring Device in Predicting Prostate Biopsy Result[NCT04339920] | 0 participants (Actual) | Observational | 2021-09-01 | Withdrawn (stopped due to No funding) | |||
| To Identify Potential New Urine Marker Panel for Cancer Screening[NCT04689802] | 2,500 participants (Anticipated) | Observational | 2021-01-20 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for putrescine and Colonic Neoplasms
| Article | Year |
|---|---|
Channelling of arginine in NO and polyamine pathways in colonocytes and consequences.
Topics: Agmatine; Animals; Arginine; Caco-2 Cells; Cell Proliferation; Colon; Colonic Neoplasms; Epithelial | 2011 |
Polyamines and colon cancer.
Topics: Antineoplastic Agents; Biogenic Polyamines; Biomarkers, Tumor; Colonic Neoplasms; Humans; Putrescine | 2003 |
1 trial available for putrescine and Colonic Neoplasms
| Article | Year |
|---|---|
Effect of alpha-difluoromethylornithine on rectal mucosal levels of polyamines in a randomized, double-blinded trial for colon cancer prevention.
Topics: Adult; Aged; Aged, 80 and over; Anticarcinogenic Agents; Audiometry; Colonic Neoplasms; Double-Blind | 1998 |
50 other studies available for putrescine and Colonic Neoplasms
| Article | Year |
|---|---|
alpha-Methyl polyamines: metabolically stable spermidine and spermine mimics capable of supporting growth in cells depleted of polyamines.
Topics: Animals; Cell Division; Cell Line, Transformed; Colonic Neoplasms; Eflornithine; Humans; Leukemia L1 | 1992 |
Dietary Polyamines Intake and Risk of Colorectal Cancer: A Case-Control Study.
Topics: Adult; Aged; Case-Control Studies; China; Colonic Neoplasms; Diet; Female; Humans; Male; Middle Aged | 2020 |
Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer.
Topics: Aged; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Female; Humans; Liver Neop | 2013 |
Effects of Lactobacillus rhamnosus GG on proliferation and polyamine metabolism in HGC-27 human gastric and DLD-1 colonic cancer cell lines.
Topics: Biogenic Polyamines; Biosynthetic Pathways; Cell Extracts; Cell Line, Tumor; Cell Proliferation; Cel | 2009 |
Polyamine transport is mediated by both endocytic and solute carrier transport mechanisms in the gastrointestinal tract.
Topics: Animals; Biological Transport; Catalysis; Caveolae; Caveolin 1; Cell Line, Tumor; Colonic Neoplasms; | 2010 |
Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis.
Topics: Acetyltransferases; Animals; Bacterial Toxins; Bacteroides fragilis; Cell Line; Cell Proliferation; | 2011 |
Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells.
Topics: Acetyltransferases; Apoptosis; Caco-2 Cells; Caspase 3; Caspase 9; Colonic Neoplasms; Cyclin-Depende | 2012 |
Cytotoxic effects of the polyamine oxidase inactivator MDL 72527 to two human colon carcinoma cell lines SW480 and SW620.
Topics: Biogenic Polyamines; Cell Cycle; Cell Division; Cell Survival; Colonic Neoplasms; Dose-Response Rela | 2002 |
Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Biological Transport; Cell Cycle; Cell Di | 2003 |
Prostaglandin-independent effects of aspirin on cell cycle and putrescine synthesis in human colon carcinoma cells.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Caco-2 Ce | 2003 |
Cyclooxygenase-independent induction of apoptosis by sulindac sulfone is mediated by polyamines in colon cancer.
Topics: Acetyltransferases; Apoptosis; Blotting, Northern; Blotting, Western; Caco-2 Cells; Cell Membrane; C | 2003 |
Inhibition of human colon carcinoma cell growth by ammonia: a non-cytotoxic process associated with polyamine synthesis reduction.
Topics: Ammonia; Ammonium Chloride; Biogenic Polyamines; Cell Cycle; Cell Differentiation; Cell Division; Co | 2003 |
Potentiation of apple procyanidin-triggered apoptosis by the polyamine oxidase inactivator MDL 72527 in human colon cancer-derived metastatic cells.
Topics: Antineoplastic Agents; Apoptosis; Biflavonoids; Catechin; Cell Line, Tumor; Cell Proliferation; Colo | 2006 |
Sensitization of human colon adenocarcinoma cells (LoVo) to reactive oxygen species by a lysosomotropic compound.
Topics: Adenocarcinoma; Aldehydes; Amine Oxidase (Copper-Containing); Animals; Antineoplastic Combined Chemo | 2006 |
Perturbation of polyamine metabolism and its relation to cell death in human colon cancer cells treated by 7beta-hydroxycholesterol and 7beta-hydroxysitosterol.
Topics: Biogenic Polyamines; Caco-2 Cells; Cell Death; Cell Growth Processes; Colonic Neoplasms; Drug Synerg | 2006 |
Modulation by polyamines of apoptotic pathways triggered by procyanidins in human metastatic SW620 cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Enzy | 2008 |
Polyamines in colorectal cancer.
Topics: Aged; Colonic Neoplasms; Female; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Polya | 1984 |
Rapid detection of polyamines in the sera of patients with colorectal carcinoma by liquid ion-exchange chromatography.
Topics: Aged; Cadaverine; Chromatography, Ion Exchange; Colonic Neoplasms; Female; Humans; Male; Middle Aged | 1980 |
Metabolism of L-arginine through polyamine and nitric oxide synthase pathways in proliferative or differentiated human colon carcinoma cells.
Topics: Adenocarcinoma; Arginine; Cell Differentiation; Cell Division; Colonic Neoplasms; Dipeptidyl Peptida | 1995 |
Inhibition of the growth of various human and mouse tumor cells by 1,15-bis(ethylamino)-4,8,12-triazapentadecane.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Breast Neoplas | 1995 |
EGF stimulates polyamine uptake in Caco-2 cells.
Topics: Adenocarcinoma; Biological Transport; Cell Differentiation; Colonic Neoplasms; Cycloheximide; Epider | 1995 |
Selenium and difluoromethylornithine additively inhibit DMH-induced distal colon tumor formation in rats fed a fiber-free diet.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colon; Colonic Neoplasms; Diet; Dietary Fiber; Dimethyl | 1993 |
Polyamines, diamine oxidase, and ornithine decarboxylase activity in colorectal cancer and in normal surrounding mucosa.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amine Oxidase (Copper-Containing); Biomarkers, Tumor | 1993 |
Quantitative and qualitative characterization of 1H NMR spectra of colon tumors, normal mucosa and their perchloric acid extracts: decreased levels of myo-inositol in tumours can be detected in intact biopsies.
Topics: Biopsy; Colonic Neoplasms; Female; Glutathione; Humans; Inositol; Intestinal Mucosa; Magnetic Resona | 1996 |
Dissimilar activation patterns of the carcinogen dimethylhydrazine (DMH) on intracellular polyamine metabolism in various organs.
Topics: 1,2-Dimethylhydrazine; Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Carcinogens; C | 1996 |
Suppression of preneoplastic changes in the intestine of rats fed low levels of polyamines.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cell Movement; Colon; Colonic Neoplasms; Dimethylhydraz | 1997 |
Growth arrest- and polyamine-dependent expression of spermidine/spermine N1-acetyltransferase in human tumor cells.
Topics: Acetyltransferases; Blotting, Northern; Cell Division; Colonic Neoplasms; Dactinomycin; Eflornithine | 1996 |
S-adenosylmethionine decarboxylase activity and utilization of exogenous putrescine are enhanced in colon cancer cells stimulated to grow by EGF.
Topics: Adenosylmethionine Decarboxylase; Caco-2 Cells; Cell Division; Colonic Neoplasms; Dose-Response Rela | 1998 |
Lipopolysaccharide of Escherichia coli, polyamines, and acetic acid stimulate cell proliferation in intestinal epithelial cells.
Topics: Acetaldehyde; Acetic Acid; Adenocarcinoma; Ammonium Chloride; Animals; Cadaverine; Cell Division; Ce | 1999 |
Low-dose deoxycholic acid stimulates putrescine uptake in colon cancer cells (Caco-2).
Topics: Caco-2 Cells; Cell Division; Colonic Neoplasms; Deoxycholic Acid; Dose-Response Relationship, Drug; | 2000 |
Blood polyamine levels after oral ornithine load, a diagnostic marker of hyperproliferative premalignant and malignant stages in a model of colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Biotransformation; Body | 2000 |
Urinary polyamine levels in human cancer.
Topics: Adenocarcinoma; Adenoma; Bone Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous | 1975 |
Biological markers of human tumors and monitoring of cancer treatment.
Topics: Alkaline Phosphatase; alpha-Fetoproteins; Bone Neoplasms; Carcinoembryonic Antigen; Choriocarcinoma; | 1979 |
Serum polyamine alterations in surgical patients with colorectal carcinoma.
Topics: Colonic Diseases; Colonic Neoplasms; Female; Humans; Male; Middle Aged; Polyamines; Putrescine; Rect | 1977 |
Preliminary longitudinal studies of serum polyamines in patients with colorectal carcinoma.
Topics: Adenocarcinoma; Colonic Neoplasms; Humans; Intestinal Polyps; Longitudinal Studies; Middle Aged; Pro | 1977 |
Reduced growth rate of dimethylhydrazine-induced colon tumors in rats.
Topics: Animals; Body Weight; Cell Division; Colonic Neoplasms; Dimethylhydrazines; Eflornithine; Male; Mito | 1992 |
[Inhibition by polyamine biosynthesis inhibitor DFMO of the growth of transplanted human colon cancer in nude mice].
Topics: Animals; Bone Marrow; Cecal Neoplasms; Colonic Neoplasms; Eflornithine; Humans; Mice; Mice, Inbred B | 1991 |
Inhibition by putrescine of experimental carcinogenesis in rat colon induced by azoxymethane.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Body Weight; Carcinoma in Situ; Cell Transformation, | 1991 |
[Raised polyamines in erythrocytes of DMH administrated rats with colonic cancers and those relationship to tumor volume].
Topics: 1,2-Dimethylhydrazine; Animals; Colonic Neoplasms; Dimethylhydrazines; Erythrocytes; Male; Putrescin | 1991 |
Effect of polyamine oxidase inhibition on the colonic malignant transformation process induced by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Acetyltransferases; Adenocarcinoma; Animals; Base Sequence; Carcinogens; Colo | 1990 |
Polyamines in colorectal cancer. Evaluation of polyamine concentrations in the colon tissue, serum, and urine of 50 patients with colorectal cancer.
Topics: Antigens, Tumor-Associated, Carbohydrate; Cadaverine; Carcinoembryonic Antigen; Colon; Colonic Neopl | 1990 |
Polyamines in colorectal cancer. Evaluation of polyamine concentrations in the colon tissue, serum, and urine of 50 patients with colorectal cancer.
Topics: Antigens, Tumor-Associated, Carbohydrate; Cadaverine; Carcinoembryonic Antigen; Colon; Colonic Neopl | 1990 |
Polyamines in colorectal cancer. Evaluation of polyamine concentrations in the colon tissue, serum, and urine of 50 patients with colorectal cancer.
Topics: Antigens, Tumor-Associated, Carbohydrate; Cadaverine; Carcinoembryonic Antigen; Colon; Colonic Neopl | 1990 |
Polyamines in colorectal cancer. Evaluation of polyamine concentrations in the colon tissue, serum, and urine of 50 patients with colorectal cancer.
Topics: Antigens, Tumor-Associated, Carbohydrate; Cadaverine; Carcinoembryonic Antigen; Colon; Colonic Neopl | 1990 |
Potentiation of natural killer cell activity and tumor immunity by diacetylputrescine.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Colonic Neoplasms; Cytotoxicity, Immunolo | 1990 |
Modulation of growth gene expression by selective alteration of polyamines in human colon carcinoma cells.
Topics: Adenosine; Blotting, Northern; Cell Division; Cell Line; Colonic Neoplasms; Eflornithine; Gene Expre | 1989 |
Putrescine uptake and release by colon cancer cells.
Topics: Amiloride; Asparagine; Blood Physiological Phenomena; Colonic Neoplasms; Humans; Putrescine; Sodium; | 1989 |
Urinary excretion of N1-acetylspermidine and other acetylated and free polyamines in the 1,2-dimethylhydrazine model of experimental rat colon cancer.
Topics: 1,2-Dimethylhydrazine; Acetylation; Animals; Biogenic Polyamines; Biomarkers, Tumor; Colonic Neoplas | 1989 |
Erythrocyte polyamine levels during intravenous feeding of patients with colorectal carcinoma.
Topics: Colonic Neoplasms; Erythrocytes; Humans; Parenteral Nutrition; Polyamines; Prealbumin; Putrescine; R | 1986 |
Polyamine levels and gastrin receptors in colon cancers.
Topics: Carcinoma; Colonic Neoplasms; Humans; Intestinal Mucosa; Neoplasm Staging; Polyamines; Putrescine; R | 1988 |
Relationship of erythrocyte polyamine levels and growth rate of transplantable tumors in rats.
Topics: Animals; Colonic Neoplasms; Fibrosarcoma; Hematocrit; Male; Neoplasms, Experimental; Polyamines; Put | 1986 |
Urinary polyamines in colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Colitis, Ulcerative; Colonic N | 1986 |
Elevation of putrescine and spermidine in sera of patients with solid tumors.
Topics: Autoanalysis; Breast Neoplasms; Cadaverine; Carbon Radioisotopes; Carcinoma; Chromatography, Ion Exc | 1974 |