putrescine has been researched along with Colitis in 6 studies
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Further, ETBF-induced colitis in C57BL/6 mice is associated with increased SMO expression and treatment of mice with an inhibitor of polyamine catabolism, N(1),N(4)-bis(2,3-butandienyl)-1,4-butanediamine (MDL 72527), significantly reduces ETBF-induced chronic inflammation and proliferation." | 3.77 | Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis. ( Casero, RA; Destefano Shields, CE; Goodwin, AC; Hacker-Prietz, A; Huso, DL; Murray-Stewart, TR; Rabizadeh, S; Sears, CL; Woster, PM; Wu, S; Wu, X, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peng, V | 1 |
| Cao, S | 1 |
| Trsan, T | 1 |
| Bando, JK | 1 |
| Avila-Pacheco, J | 1 |
| Cleveland, JL | 2 |
| Clish, C | 1 |
| Xavier, RJ | 1 |
| Colonna, M | 1 |
| Grosheva, I | 1 |
| Zheng, D | 1 |
| Levy, M | 1 |
| Polansky, O | 1 |
| Lichtenstein, A | 1 |
| Golani, O | 1 |
| Dori-Bachash, M | 1 |
| Moresi, C | 1 |
| Shapiro, H | 1 |
| Del Mare-Roumani, S | 1 |
| Valdes-Mas, R | 1 |
| He, Y | 1 |
| Karbi, H | 1 |
| Chen, M | 1 |
| Harmelin, A | 1 |
| Straussman, R | 1 |
| Yissachar, N | 1 |
| Elinav, E | 1 |
| Geiger, B | 1 |
| Nakamura, A | 1 |
| Kurihara, S | 1 |
| Takahashi, D | 1 |
| Ohashi, W | 1 |
| Nakamura, Y | 1 |
| Kimura, S | 1 |
| Onuki, M | 1 |
| Kume, A | 1 |
| Sasazawa, Y | 1 |
| Furusawa, Y | 1 |
| Obata, Y | 1 |
| Fukuda, S | 1 |
| Saiki, S | 1 |
| Matsumoto, M | 1 |
| Hase, K | 1 |
| Rossi, G | 1 |
| Cerquetella, M | 1 |
| Pengo, G | 1 |
| Mari, S | 1 |
| Balint, E | 1 |
| Bassotti, G | 1 |
| Manolescu, N | 1 |
| Hardbower, DM | 1 |
| Asim, M | 1 |
| Luis, PB | 1 |
| Singh, K | 1 |
| Barry, DP | 1 |
| Yang, C | 1 |
| Steeves, MA | 1 |
| Schneider, C | 1 |
| Piazuelo, MB | 1 |
| Gobert, AP | 1 |
| Wilson, KT | 1 |
| Goodwin, AC | 1 |
| Destefano Shields, CE | 1 |
| Wu, S | 1 |
| Huso, DL | 1 |
| Wu, X | 1 |
| Murray-Stewart, TR | 1 |
| Hacker-Prietz, A | 1 |
| Rabizadeh, S | 1 |
| Woster, PM | 1 |
| Sears, CL | 1 |
| Casero, RA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Supplementation With L-ornithine Increases Representation Density of CD68+ and CD163+ Macrophages in Human Periodontitis Gingiva and Can Modulate Macrophages Phenotypes. Randomized Controlled Pilot Trial[NCT05042024] | Phase 3 | 75 participants (Actual) | Interventional | 2017-10-20 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for putrescine and Colitis
| Article | Year |
|---|---|
Ornithine decarboxylase supports ILC3 responses in infectious and autoimmune colitis through positive regulation of IL-22 transcription.
Topics: Animals; Anti-Bacterial Agents; Colitis; Enterobacteriaceae Infections; Immunity, Innate; Interleuki | 2022 |
High-Throughput Screen Identifies Host and Microbiota Regulators of Intestinal Barrier Function.
Topics: Animals; Caco-2 Cells; Citrobacter rodentium; Colitis; Colon; Dextran Sulfate; Disease Models, Anima | 2020 |
Symbiotic polyamine metabolism regulates epithelial proliferation and macrophage differentiation in the colon.
Topics: Animals; Cell Differentiation; Cell Proliferation; Colitis; Colon; Dextran Sulfate; Epithelial Cells | 2021 |
Immunohistochemical expression of ornithine decarboxylase, diamine oxidase, putrescine, and spermine in normal canine enterocolic mucosa, in chronic colitis, and in colorectal cancer.
Topics: Amine Oxidase (Copper-Containing); Animals; Chronic Disease; Colitis; Colorectal Neoplasms; Dogs; In | 2015 |
Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications.
Topics: Animals; Cell Line; Citrobacter rodentium; Colitis; Colon; Cytokines; Enterobacteriaceae Infections; | 2017 |
Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis.
Topics: Acetyltransferases; Animals; Bacterial Toxins; Bacteroides fragilis; Cell Line; Cell Proliferation; | 2011 |