putrescine has been researched along with Chagas Disease in 5 studies
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chagas disease, also known as American trypanosomiasis, is a neglected tropical disease caused by the protozoa Trypanosoma cruzi, affecting nearly 7 million people only in the Americas." | 1.91 | A combined ligand and target-based virtual screening strategy to repurpose drugs as putrescine uptake inhibitors with trypanocidal activity. ( Alba Soto, CD; Alberca, LN; Carrillo, C; Fraccaroli, L; Gavernet, L; Llanos, MA; Miranda, C; Pino-Martinez, A; Ruiz, MD; Sbaraglini, ML; Talevi, A, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Llanos, MA | 2 |
| Alberca, LN | 3 |
| Ruiz, MD | 3 |
| Sbaraglini, ML | 2 |
| Miranda, C | 2 |
| Pino-Martinez, A | 2 |
| Fraccaroli, L | 2 |
| Carrillo, C | 3 |
| Alba Soto, CD | 2 |
| Gavernet, L | 3 |
| Talevi, A | 3 |
| Dietrich, RC | 1 |
| Palestro, PH | 1 |
| Seguel, V | 1 |
| Castro, L | 1 |
| Reigada, C | 1 |
| Cortes, L | 1 |
| Díaz, MV | 1 |
| Miranda, MR | 1 |
| Pereira, CA | 1 |
| Lapier, M | 1 |
| Campos-Estrada, C | 1 |
| Morello, A | 1 |
| Kemmerling, U | 1 |
| Maya, JD | 1 |
| López-Muñoz, R | 1 |
| Majumder, S | 1 |
| Kierszenbaum, F | 1 |
| Freire-de-Lima, CG | 1 |
| Nascimento, DO | 1 |
| Soares, MB | 1 |
| Bozza, PT | 1 |
| Castro-Faria-Neto, HC | 1 |
| de Mello, FG | 1 |
| DosReis, GA | 1 |
| Lopes, MF | 1 |
5 other studies available for putrescine and Chagas Disease
| Article | Year |
|---|---|
A combined ligand and target-based virtual screening strategy to repurpose drugs as putrescine uptake inhibitors with trypanocidal activity.
Topics: Chagas Disease; Danazol; Humans; Ligands; Membrane Transport Proteins; Polyamines; Putrescine; Quine | 2023 |
A combined ligand and target-based virtual screening strategy to repurpose drugs as putrescine uptake inhibitors with trypanocidal activity.
Topics: Chagas Disease; Danazol; Humans; Ligands; Membrane Transport Proteins; Polyamines; Putrescine; Quine | 2023 |
A combined ligand and target-based virtual screening strategy to repurpose drugs as putrescine uptake inhibitors with trypanocidal activity.
Topics: Chagas Disease; Danazol; Humans; Ligands; Membrane Transport Proteins; Polyamines; Putrescine; Quine | 2023 |
A combined ligand and target-based virtual screening strategy to repurpose drugs as putrescine uptake inhibitors with trypanocidal activity.
Topics: Chagas Disease; Danazol; Humans; Ligands; Membrane Transport Proteins; Polyamines; Putrescine; Quine | 2023 |
Identification of cisapride as new inhibitor of putrescine uptake in Trypanosoma cruzi by combined ligand- and structure-based virtual screening.
Topics: Biological Transport; Chagas Disease; Cisapride; Drug Evaluation, Preclinical; Ligands; Membrane Tra | 2018 |
Pentamidine antagonizes the benznidazole's effect in vitro, and lacks of synergy in vivo: Implications about the polyamine transport as an anti-Trypanosoma cruzi target.
Topics: Animals; Chagas Disease; Chlorocebus aethiops; DNA, Protozoan; Dose-Response Relationship, Drug; Glu | 2016 |
N,N'-thiophene-substituted polyamine analogs inhibit mammalian host cell invasion and intracellular multiplication of Trypanosoma cruzi.
Topics: Animals; Cell Division; Chagas Disease; Heart; Host-Parasite Interactions; Kinetics; Mice; Mice, Inb | 1993 |
Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Cells, Cultured; Chagas Disease; Cysteine Prote | 2000 |