putrescine has been researched along with Carcinoma, Hepatocellular in 16 studies
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our previous study showed that treatment of highly invasive rat ascites hepatoma (LC-AH) cells with alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase, decreased both their intracellular level of putrescine and their in vitro invasion of a monolayer of calf pulmonary arterial endothelial (CPAE) cells, and that both these decreases were completely reversed by exogenous putrescine, but not spermidine or spermine." | 7.70 | Putrescine-stimulated intracellular Ca2+ release for invasiveness of rat ascites hepatoma cells. ( Ashida, Y; Inoue, H; Miwa, Y; Miyoshi, K; Ueno, A, 1998) |
| "Our previous study showed that treatment of highly invasive rat ascites hepatoma (LC-AH) cells with alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase, decreased both their intracellular level of putrescine and their in vitro invasion of a monolayer of calf pulmonary arterial endothelial (CPAE) cells, and that both these decreases were completely reversed by exogenous putrescine, but not spermidine or spermine." | 3.70 | Putrescine-stimulated intracellular Ca2+ release for invasiveness of rat ascites hepatoma cells. ( Ashida, Y; Inoue, H; Miwa, Y; Miyoshi, K; Ueno, A, 1998) |
| "Isoornithines were not taken up by H-35 hepatoma cells; hence they did not affect their ODC activity." | 1.29 | Synthesis of isoornithines and methylputrescines. An evaluation of their inhibitory effects on ornithine decarboxylase. ( Aizencang, G; Frydman, B; Frydman, RB; Giorgieri, S; Guerra, L; Sambrotta, L, 1995) |
| "Macrophage-like RAW 264 and H35 hepatoma cells grown under serum-free conditions exported putrescine and an unidentified diamine into the culture medium." | 1.29 | Biosynthesis and selective export of 1,5-diaminopentane (cadaverine) in mycoplasma-free cultured mammalian cells. ( Byus, CV; Fukumoto, GH; Hawel, L; Tjandrawinata, RR, 1994) |
| "Kinetic analyses showed that liver and hepatoma enzymes had a similar Km and Vmax for putrescine incorporation into cell protein." | 1.26 | Differential transglutaminase distribution in normal rat liver and rat hepatoma. ( Birckbichler, PJ; Orr, GR; Patterson, MK, 1976) |
| "Quiescent, contact inhibited H-35 rat hepatoma cell cultures maintained in minimal essential medium contain a very low level of ornithine decarboxylase activity." | 1.26 | The appearance of an ornithine decarboxylase inhibitory protein upon the addition of putrescine to cell cultures. ( Canellakis, ES; Fong, WF; Heller, JS, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (68.75) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aizencang, G | 1 |
| Frydman, RB | 1 |
| Giorgieri, S | 1 |
| Sambrotta, L | 1 |
| Guerra, L | 1 |
| Frydman, B | 1 |
| Santos, AA | 1 |
| Stubbs, AP | 1 |
| Maghsoudloo, M | 1 |
| Murphy, GM | 1 |
| Wilkinson, ML | 1 |
| Hawel, L | 1 |
| Tjandrawinata, RR | 1 |
| Fukumoto, GH | 1 |
| Byus, CV | 1 |
| Ashida, Y | 1 |
| Ueno, A | 1 |
| Miwa, Y | 1 |
| Miyoshi, K | 1 |
| Inoue, H | 1 |
| Birckbichler, PJ | 1 |
| Orr, GR | 1 |
| Patterson, MK | 1 |
| McCann, PP | 2 |
| Tardiff, C | 1 |
| Mamont, PS | 2 |
| Schuber, F | 1 |
| Russell, DH | 2 |
| Looney, WB | 2 |
| Kovacs, CJ | 2 |
| Hopkins, HA | 2 |
| Dattilo, JW | 1 |
| Morris, HP | 2 |
| Katsuta, H | 1 |
| Takaoka, T | 1 |
| Nose, K | 1 |
| Nagai, Y | 1 |
| Fong, WF | 1 |
| Heller, JS | 1 |
| Canellakis, ES | 1 |
| Tardif, C | 1 |
| Perin, A | 1 |
| Sessa, A | 1 |
| Takeda, T | 1 |
| Nishiguchi, S | 1 |
| Kuroki, T | 1 |
| Kobayashi, K | 1 |
| Hasuma, T | 1 |
| Matsui-Yuasa, I | 1 |
| Otani, S | 1 |
| Williams-Ashman, HG | 2 |
| Coppoc, GL | 2 |
| Weber, G | 1 |
| Jänne, J | 1 |
| Geroch, ME | 1 |
| Schenone, A | 1 |
| Harik, SI | 1 |
| Hollenberg, MD | 1 |
| Snyder, SH | 1 |
| Marton, LJ | 1 |
| LeGendre, SM | 1 |
1 review available for putrescine and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
New aspects of polyamine biosynthesis in eukaryotic organisms.
Topics: Animals; Azotobacter; Carboxy-Lyases; Carcinoma, Hepatocellular; Catalysis; Chickens; Escherichia co | 1972 |
15 other studies available for putrescine and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Synthesis of isoornithines and methylputrescines. An evaluation of their inhibitory effects on ornithine decarboxylase.
Topics: Animals; Binding, Competitive; Carcinoma, Hepatocellular; Enzyme Inhibitors; Liver; Liver Neoplasms; | 1995 |
Polyamine metabolism in human hepatocellular cancer cells (Hep-G2).
Topics: Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; DNA, Neoplasm; Eflornithine; Humans; Liv | 1994 |
Biosynthesis and selective export of 1,5-diaminopentane (cadaverine) in mycoplasma-free cultured mammalian cells.
Topics: Amino Acids; Animals; Biological Transport; Cadaverine; Carcinoma, Hepatocellular; Cell Line; Cultur | 1994 |
Putrescine-stimulated intracellular Ca2+ release for invasiveness of rat ascites hepatoma cells.
Topics: Animals; Ascites; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Carcinoma, Hepatocell | 1998 |
Differential transglutaminase distribution in normal rat liver and rat hepatoma.
Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Cytoplasm; Fema | 1976 |
Biphasic induction of ornithine decarboxylase and putrescine levels in growing HTC cells.
Topics: Animals; Blood; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cattle; Cell Line; | 1975 |
Changes in serum putrescine and spermidine levels following local radiation to hepatoma 3924A of the rat.
Topics: Animals; Carcinoma, Hepatocellular; Female; Liver Neoplasms; Neoplasms, Experimental; Putrescine; Ra | 1976 |
Effects of polyamines on the proliferation of mammalian cells in tissue culture.
Topics: Agmatine; Animals; Carcinoma, Hepatocellular; Cell Division; Culture Techniques; Fibroblasts; Liver; | 1975 |
The appearance of an ornithine decarboxylase inhibitory protein upon the addition of putrescine to cell cultures.
Topics: Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Culture Media; Cycloheximide; Dactinomycin; Ki | 1976 |
Regulation of ornithine decarboxylase by ODC-antizyme in HTC cells.
Topics: Cadaverine; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Dose- | 1977 |
Changes in polyamine levels and protein synthesis rate during rat liver carcinogenesis induced by 4-dimethylaminoazobenzene.
Topics: Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Male; Neoplasm Proteins; Neoplasms, Experimenta | 1978 |
Reduction by interferon-alpha of levels of c-myc protein and DNA synthesis in a human hepatoma cell line mediated by inhibition of putrescine synthesis.
Topics: Blotting, Northern; Carcinoma, Hepatocellular; Cell Line; DNA Replication; Humans; Interferon Type I | 1991 |
Imbalance in ornithine metabolism in hepatomas of different growth rates as expressed in formation of putrescine, spermidine, and spermine.
Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Electrophoresis, Paper; Liver; Liver Neoplasms; | 1972 |
Alpha-hydrazino-ornithine blocks net synthesis of putrescine but not of RNA and DNA.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Depression, Chemical; DNA; Hepatectomy; Hydrazi | 1974 |
Polyamine depletion of tumor tissue and subsequent elevation of spermidine in the sera of rats with 3924A hepatomas after 5-fluorouracil administration.
Topics: Animals; Carcinoma, Hepatocellular; Female; Fluorouracil; Liver; Liver Neoplasms; Neoplasms, Experim | 1974 |