putrescine and Cancer of Prostate studies

Research Excerpts

Excerpt	Relevance	Reference
"To evaluate [1-11C]putrescine ([11C]PUT) as a potential tracer for imaging and characterization of human prostatic adenocarcinoma, positron emission tomography (PET) was performed in eight patients and three normal controls."	7.69	Positron emission tomography study of human prostatic adenocarcinoma using carbon-11 putrescine. ( Fowler, JS; MacGregor, RR; Madajewicz, S; Schlyer, DJ; Volkow, ND; Wang, GJ; Wolf, AP, 1994)
"To evaluate [1-11C]putrescine ([11C]PUT) as a potential tracer for imaging and characterization of human prostatic adenocarcinoma, positron emission tomography (PET) was performed in eight patients and three normal controls."	3.69	Positron emission tomography study of human prostatic adenocarcinoma using carbon-11 putrescine. ( Fowler, JS; MacGregor, RR; Madajewicz, S; Schlyer, DJ; Volkow, ND; Wang, GJ; Wolf, AP, 1994)
"Urinary excretion of the basic polyamine, spermidine, was significantly elevated in patients with prostatic carcinoma as compared to a control group of patients, Of 44 urine specimens from patients with prostatic malignancy 31 had spermidine levels more than 2 mg."	3.65	Urinary polyamine levels in the diagnosis of carcinoma of the prostate. ( Brorsson, U; Fair, WR; Wehner, N, 1975)
"Putrescine is a small molecule that may prove difficult for use for synthesizing stable toxin derivatives that can take advantage of the targeting potential of the polyamine transporter."	2.38	Prostatic polyamines and polyamine targeting as a new approach to therapy of prostatic cancer. ( Heston, WD, 1991)
"The strategy is applied to a prostate cancer patient cohort where data from MR spectroscopy and gene expression have been collected from and integrated on the exact same tissue samples."	1.43	A Balanced Tissue Composition Reveals New Metabolic and Gene Expression Markers in Prostate Cancer. ( Angelsen, A; Bathen, TF; Bertilsson, H; Drabløs, F; Rye, MB; Tessem, MB, 2016)
"PCa, benign prostatic hyperplasia (BPH) patients and healthy controls (HC) showing PSA>4."	1.43	Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. ( Chan, CF; Chan, WL; Chiu, KF; Ng, CF; Tsoi, TH; Wong, KL; Wong, WT, 2016)
"Putrescine is a potential scanning agent for metastases of prostatic carcinoma."	1.27	alpha-Difluoromethylornithine enhancement of 14C-putrescine uptake by an androgen-dependent prostatic tumor. ( Heston, WD; Kadmon, D, 1986)
"Putrescine was able to block the cytotoxic effect of AZP."	1.27	Cytotoxic activity of a polyamine analogue, monoaziridinylputrescine, against the PC-3 human prostatic carcinoma cell line. ( Covey, DF; Heston, WD; Pliner, L; Russo, P; Yang, CR, 1987)
"There were 105 patients with these tumors; 319 polyamine determinations were obtained from this subset of patients."	1.26	Further evidence for the use of polyamines as biochemical markers for malignant tumors. ( Beal, SL; Horn, Y; Lubich, WP; Marton, LJ; Spigel, L; Walach, N, 1982)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (47.06)	18.7374
1990's	9 (26.47)	18.2507
2000's	7 (20.59)	29.6817
2010's	2 (5.88)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Tessem, MB	1
Bertilsson, H	1
Angelsen, A	1
Bathen, TF	1
Drabløs, F	1
Rye, MB	1
Tsoi, TH	1
Chan, CF	1
Chan, WL	1
Chiu, KF	1
Wong, WT	1
Ng, CF	1
Wong, KL	1
Basu, HS	1
Thompson, TA	1
Church, DR	1
Clower, CC	1
Mehraein-Ghomi, F	1
Amlong, CA	1
Martin, CT	1
Woster, PM	2
Lindstrom, MJ	1
Wilding, G	3
Desury, G	1
Moulinoux, JP	4
Delcros, JG	1
Kee, K	1
Vujcic, S	1
Merali, S	1
Diegelman, P	1
Kisiel, N	1
Powell, CT	1
Kramer, DL	1
Porter, CW	1
Russo, A	1
Piovano, M	1
Clericuzio, M	1
Lombardo, L	1
Tabasso, S	1
Chamy, MC	1
Vidari, G	1
Cardile, V	1
Vita-Finzi, P	1
Garbarino, JA	1
Dunzendorfer, U	2
Heston, WD	7
Kadmon, D	4
Covey, DF	4
Fair, WR	5
Lazan, DW	1
Horn, Y	2
Beal, SL	1
Walach, N	1
Lubich, WP	1
Spigel, L	2
Marton, LJ	2
Smith, RC	1
Litwin, MS	1
Lu, Y	1
Zetter, BR	1
Brachet, P	1
Quemener, V	3
Havouis, R	3
Tomé, D	1
Cipolla, B	2
Blanchard, Y	1
Chamaillard, L	1
Guillé, F	2
Jeffers, L	1
Church, D	1
Basu, H	1
Marton, L	1
Wang, GJ	1
Volkow, ND	1
Wolf, AP	1
Madajewicz, S	1
Fowler, JS	1
Schlyer, DJ	1
MacGregor, RR	1
Messing, EM	1
Love, RR	1
Tutsch, KD	1
Verma, AK	1
Douglas, J	1
Pomplun, M	1
Simsiman, R	1
McCloskey, DE	1
Casero, RA	1
Davidson, NE	1
Simoneau, AR	1
Gerner, EW	1
Phung, M	1
McLaren, CE	1
Meyskens, FL	1
Srinath, P	1
McQuarrie, SA	1
Suresh, MR	1
Welch, MJ	3
Coleman, RE	1
Straatmann, MG	1
Asberry, BE	1
Primeau, JL	1
Ter-Pogossian, MM	1
Sanford, EJ	1
Drago, JR	1
Rohner, TJ	1
Kessler, GF	1
Sheehan, L	1
Lipton, A	1
Wehner, N	1
Brorsson, U	1
Martin, C	1
Lobel, B	1
Seiler, N	1
Hwang, DR	2
Mathias, CJ	2
McGuire, AH	1
Knöner, M	1
Lang, LX	1
Yang, CR	1
Pliner, L	1
Russo, P	1
Watanabe, KA	1
Pankiewicz, KW	1
Shukla, GS	1
Singhal, RL	1
Uy, L	1
Mann, T	1

Trial	Enrollment	Study Type	Start Date	Status
Artificial Intelligence (AI)-Assisted Risk-based Prostate Cancer Detection: A Synergy of Novel Biomarkers, Advanced Imaging, and Robotic-assisted Diagnosis[NCT05443412]	510 participants (Anticipated)	Observational	2022-08-01	Not yet recruiting
To Evaluate the Performance of a Urine Spermine Measuring Device in Predicting Prostate Biopsy Result[NCT04339920]	0 participants (Actual)	Observational	2021-09-01	Withdrawn (stopped due to No funding)
To Investigate the Diagnostic Accuracy of Exosomal microRNA in Predicting the Aggressiveness of Prostate Cancer in Chinese Patients[NCT03911999]	180 participants (Actual)	Observational	2018-05-03	Completed
To Identify Potential New Urine Marker Panel for Cancer Screening[NCT04689802]	2,500 participants (Anticipated)	Observational	2021-01-20	Recruiting
To Investigate the Role of Gut Microbiome in Androgen Deprivation Therapy Related Metabolic Changes in Prostate Cancer Patients[NCT04687709]	50 participants (Anticipated)	Observational	2021-01-14	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Prostatic polyamines and polyamine targeting as a new approach to therapy of prostatic cancer. Cancer surveys, 1991, Volume: 11 Topics: Aziridines; Biological Transport; Cell Division; Dihydrotestosterone; Eflornithine; Guanidines; Huma	1991
Secretory function of the prostate, seminal vesicle and other male accessory organs of reproduction. Journal of reproduction and fertility, 1974, Volume: 37, Issue:1 Topics: Acid Phosphatase; Animals; Body Fluids; Bulbourethral Glands; Cattle; Citrates; Dihydrotestosterone;	1974

Article	Year
Low-dose difluoromethylornithine and polyamine levels in human prostate tissue. Journal of the National Cancer Institute, 1999, Aug-18, Volume: 91, Issue:16 Topics: Administration, Oral; Antineoplastic Agents; Eflornithine; Enzyme Inhibitors; Humans; Male; Ornithin	1999
Alpha-difluoromethylornithine and polyamine levels in the human prostate: results of a phase IIa trial. Journal of the National Cancer Institute, 2001, Jan-03, Volume: 93, Issue:1 Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Eflornithine; Enzyme Inhibitors; Humans	2001
Urinary polyamine levels in cancer patients treated with D,L-alpha-difluoromethylornithine, an inhibitor of polyamine biosynthesis. Journal of surgical oncology, 1989, Volume: 41, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Evaluation; Eflornithine; Fem	1989

putrescine and Cancer of Prostate

Research Excerpts

Research

Studies (34)

Authors

Clinical Trials (5)

Trial Overview

Reviews

Trials

Other Studies

Article	Year
A Balanced Tissue Composition Reveals New Metabolic and Gene Expression Markers in Prostate Cancer. PloS one, 2016, Volume: 11, Issue:4 Topics: Biomarkers, Tumor; Citric Acid; Cohort Studies; Fatty Acids; Gene Expression Regulation, Neoplastic;	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. PloS one, 2016, Volume: 11, Issue:9 Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato	2016
A small molecule polyamine oxidase inhibitor blocks androgen-induced oxidative stress and delays prostate cancer progression in the transgenic adenocarcinoma of the mouse prostate model. Cancer research, 2009, Oct-01, Volume: 69, Issue:19 Topics: Acetyltransferases; Adenocarcinoma; Androgens; Animals; Cell Line, Tumor; Disease Models, Animal; Di	2009
Alteration of intestinal putrescine uptake in tumour-bearing rats. International journal of oncology, 2002, Volume: 21, Issue:3 Topics: Amine Oxidase (Copper-Containing); Animals; Carbon Radioisotopes; Enterocytes; Intestinal Absorption	2002
Metabolic and antiproliferative consequences of activated polyamine catabolism in LNCaP prostate carcinoma cells. The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26 Topics: Acetyl Coenzyme A; Acetyltransferases; Adenosylmethionine Decarboxylase; Carcinoma; Cell Division; D	2004
Putrescine-1,4-dicinnamide from Pholiota spumosa (Basidiomycetes) inhibits cell growth of human prostate cancer cells. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2007, Volume: 14, Issue:2-3 Topics: Antineoplastic Agents, Phytogenic; Basidiomycota; Cell Line, Tumor; Cell Proliferation; Fruiting Bod	2007
[Therapy of prostate carcinoma with polyamine synthesis inhibitors. I. Physiological and pathophysiological principles]. Urologia internationalis, 1982, Volume: 37, Issue:5 Topics: Antineoplastic Agents; Humans; Male; Polyamines; Prostatic Hyperplasia; Prostatic Neoplasms; Putresc	1982
Differential effect of alpha-difluoromethylornithine on the in vivo uptake of 14C-labeled polyamines and methylglyoxal bis(guanylhydrazone) by a rat prostate-derived tumor. Cancer research, 1984, Volume: 44, Issue:3 Topics: Animals; Antineoplastic Agents; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Eflorni	1984
Aminoguanidine reversal of the inhibitory effects of ornithine analogs on the in vitro clonogenic survival of the R3327AT prostate-derived tumor. Cancer letters, 1981, Volume: 11, Issue:4 Topics: Amine Oxidase (Copper-Containing); Animals; Carboxy-Lyases; Cell Line; Eflornithine; Guanidines; Mal	1981
Further evidence for the use of polyamines as biochemical markers for malignant tumors. Cancer research, 1982, Volume: 42, Issue:8 Topics: Breast Neoplasms; Clinical Laboratory Techniques; Female; Genital Neoplasms, Female; Humans; Male; N	1982
Identification of an endogenous inhibitor of prostatic carcinoma cell growth. Nature medicine, 1995, Volume: 1, Issue:10 Topics: Adenocarcinoma; Animals; Enzyme Inhibitors; Growth Inhibitors; Guanidines; Humans; Male; Neoplasm In	1995
Alterations in intestinal uptake of putrescine and tissue polyamine concentrations in tumor-bearing rats. Biochimica et biophysica acta, 1994, Nov-29, Volume: 1227, Issue:3 Topics: Adenocarcinoma; Animals; Body Weight; Dose-Response Relationship, Drug; Eating; Female; Intestinal A	1994
In vivo, synergestic inhibition of MAT-LyLu rat prostatic adenocarcinoma growth by polyamine deprivation and low-dose cyclophosphamide. Urological research, 1996, Volume: 24, Issue:2 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Co	1996
Effects of the polyamine analogues BE-4-4-4-4, BE-3-7-3, and BE-3-3-3 on the proliferation of three prostate cancer cell lines. Cancer chemotherapy and pharmacology, 1997, Volume: 40, Issue:2 Topics: Animals; Antineoplastic Agents; Cell Division; Growth Inhibitors; Male; Mice; Mice, Nude; Polyamines	1997
Positron emission tomography study of human prostatic adenocarcinoma using carbon-11 putrescine. Nuclear medicine and biology, 1994, Volume: 21, Issue:1 Topics: Adenocarcinoma; Aged; Bone Neoplasms; Carbon Radioisotopes; Humans; Male; Middle Aged; Prostatic Neo	1994
Effects of the polyamine analogues N1-ethyl-N11-((cyclopropyl)methyl)-4,8-diazaundecane and N1-ethylN-11-((cycloheptyl)methyl)-4,8-diazaundecane in human prostate cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Cell Division; DNA Fragmentation; Humans; Kinetics; Male; Polyamin	2000
Comparative uptake of polyamines by prostate and non-prostate cancer cell lines. Nuclear medicine and biology, 2002, Volume: 29, Issue:4 Topics: Animals; Breast Neoplasms; Carbon Radioisotopes; Humans; Male; Ornithine; Polyamines; Prostatic Neop	2002
Carbon-11-labeled methylated polyamine analogs: uptake in prostate and tumor in animal models. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1977, Volume: 18, Issue:1 Topics: Animals; Carbon Radioisotopes; Dogs; Male; Melanoma; Methylation; Mice; Neoplasm Transplantation; Ne	1977
Preliminary evaluation of urinary polyamines in the diagnosis of genitourinary tract malignancy. The Journal of urology, 1975, Volume: 113, Issue:2 Topics: Adenocarcinoma; Carcinoma, Transitional Cell; Female; Humans; Kidney Neoplasms; Male; Polyamines; Pr	1975
Urinary polyamine levels in the diagnosis of carcinoma of the prostate. The Journal of urology, 1975, Volume: 114, Issue:1 Topics: Aged; Carcinoma; Diagnosis, Differential; Electrophoresis, Paper; Humans; Male; Middle Aged; Polyami	1975
The growth of MAT-LyLu rat prostatic adenocarcinoma can be prevented in vivo by polyamine deprivation. The Journal of urology, 1991, Volume: 146, Issue:5 Topics: Adenocarcinoma; Animals; Diet; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Eflorn	1991
Imaging prostate derived tumors with PET and N-(3-[18F]fluoropropyl)putrescine. International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1990, Volume: 17, Issue:6 Topics: Animals; Fluorine Radioisotopes; Humans; Male; Neoplasm Transplantation; Prostatic Neoplasms; Putres	1990
[Therapy with inhibitors of polyamine biosynthesis in refractory prostatic carcinoma. An experimental and clinical study]. Onkologie, 1985, Volume: 8, Issue:4 Topics: Adenocarcinoma; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Carboxy-Lyases; Ca	1985
N-3-[18F]fluoropropylputrescine as potential PET imaging agent for prostate and prostate derived tumors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1989, Volume: 30, Issue:7 Topics: Animals; Carbon Radioisotopes; Cell Line; Dihydrotestosterone; Eflornithine; Humans; Male; Prostate;	1989
alpha-Difluoromethylornithine enhancement of 14C-putrescine uptake by an androgen-dependent prostatic tumor. The Journal of urology, 1986, Volume: 136, Issue:4 Topics: Adenocarcinoma; Androgens; Animals; Carbon Radioisotopes; Dexamethasone; Dihydrotestosterone; Eflorn	1986
Cytotoxic activity of a polyamine analogue, monoaziridinylputrescine, against the PC-3 human prostatic carcinoma cell line. Cancer research, 1987, Jul-15, Volume: 47, Issue:14 Topics: Cell Line; Cell Survival; Eflornithine; Humans; Kinetics; Male; Mathematics; Prostatic Neoplasms; Pu	1987
Cytotoxic and non-cytotoxic N-alkyl derivatives of putrescine: effect on polyamine uptake and growth of prostatic cancer cells in vitro. Biochemical pharmacology, 1987, Jun-01, Volume: 36, Issue:11 Topics: Alkylation; Cell Division; Cell Line; Humans; Male; Polyamines; Prostatic Neoplasms; Putrescine; Str	1987
Hormone-independent polyamine metabolism of squamous cell carcinoma of the prostate. Cell biochemistry and function, 1985, Volume: 3, Issue:3 Topics: Adenosylmethionine Decarboxylase; Androgens; Animals; Carcinoma, Squamous Cell; Castration; Cyproter	1985
Cytotoxic activity of aziridinyl putrescine enhanced by polyamine depletion with alpha-difluoromethylornithine. Biochemical pharmacology, 1985, Jul-01, Volume: 34, Issue:13 Topics: Antineoplastic Agents; Cell Line; Eflornithine; Humans; Male; Ornithine; Polyamines; Prostatic Neopl	1985