putrescine has been researched along with Breast Cancer in 52 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " In estrogen-responsive ZR-75-1 human breast cancer cells, which display low polyamine biosynthetic activity, putrescine and spermidine were internalized with high affinity (Km = 3." | 7.69 | Hormonal and feedback regulation of putrescine and spermidine transport in human breast cancer cells. ( Lessard, M; Poulin, R; Singh, SM; Zhao, C, 1995) |
| "The diagnostic significance of three polyamines (putrescine, spermidine and spermine), of carcinoembryonic antigen and of phosphoglucose isomerase have been compared in sera of patients with breast cancer or benign breast disease and normal age matched controls." | 7.67 | Clinical significance of serum spermine in breast cancer. ( Damle, SR; Inamdar, NA; Mittra, I; Redkar, SL, 1988) |
| "Putrescine transport was inhibited by 70% by decreasing extracellular pH from 7." | 5.29 | Inorganic cation dependence of putrescine and spermidine transport in human breast cancer cells. ( Lessard, M; Poulin, R; Zhao, C, 1995) |
| " We have investigated the role of plasma-membrane potential (DeltaPsipm) in putrescine and spermidine uptake in ZR-75-1 human breast cancer cells." | 3.70 | Dependence of mammalian putrescine and spermidine transport on plasma-membrane potential: identification of an amiloride binding site on the putrescine carrier. ( Audette, M; Charest-Gaudreault, R; Poulin, R; Verma, S; Zhao, C, 1998) |
| "Polyamines-putrescine, spermidine, and spermine-are involved in the growth of breast cancer cells." | 3.70 | Activation of nuclear factor kappaB by polyamines in breast cancer cells. ( Shah, N; Shirahata, A; Sigal, LH; Thomas, T; Thomas, TJ, 1999) |
| " In estrogen-responsive ZR-75-1 human breast cancer cells, which display low polyamine biosynthetic activity, putrescine and spermidine were internalized with high affinity (Km = 3." | 3.69 | Hormonal and feedback regulation of putrescine and spermidine transport in human breast cancer cells. ( Lessard, M; Poulin, R; Singh, SM; Zhao, C, 1995) |
| "Previous studies have shown that natural polyamines-putrescine, spermidine, and spermine-play a key role in the mechanism of action of estrogens in breast cancer." | 3.69 | Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: therapeutic implications. ( Thomas, T; Thomas, TJ, 1994) |
| "These experiments were designed to test polyamine (PA) involvement in the secretion and action of transforming growth factor alpha (TGF-alpha) in hormone responsive MCF-7 breast cancer cells in liquid culture." | 3.68 | Polyamine involvement in the secretion and action of TGF-alpha in hormone sensitive human breast cancer cells in culture. ( Demers, L; Kim, I; Lynch, J; Manni, A, 1991) |
| "Polyamine levels (putrescine, spermidine and spermine) in breast cancers (n = 54) were measured as a potential guide to prognosis." | 3.67 | Polyamines in breast cancer. ( Bundred, NJ; Dixon, JM; Kingsnorth, AN; Wallace, HM, 1984) |
| " In order to gain insight into the molecular mechanism of action of antiestrogens in human breast cancer, we studied the effect of tamoxifen and 4-hydroxytamoxifen on the concentration of ODC mRNA, ODC activity, and the polyamine levels in a hormone-responsive breast cancer cell line, MCF-7." | 3.67 | Regulation of ornithine decarboxylase gene expression in MCF-7 breast cancer cells by antiestrogens. ( Butterfield, JR; Jänne, OA; Kiang, DT; Thomas, T; Trend, B, 1989) |
| "The diagnostic significance of three polyamines (putrescine, spermidine and spermine), of carcinoembryonic antigen and of phosphoglucose isomerase have been compared in sera of patients with breast cancer or benign breast disease and normal age matched controls." | 3.67 | Clinical significance of serum spermine in breast cancer. ( Damle, SR; Inamdar, NA; Mittra, I; Redkar, SL, 1988) |
| "Gene therapy has long been proposed for cancer treatment." | 1.91 | Effectiveness of a novel gene nanotherapy based on putrescine for cancer treatment. ( Alijas, S; Cascallar, M; de la Fuente, M; Gámez-Chiachio, M; Hurtado, P; López López, R; Lores, S; Moreno-Bueno, G; Piñeiro, R; Ramos-Nebot, C, 2023) |
| "Though hyperglycemia has been considered as a fuel for growth of cancer cells, pathways leading to this condition are still under investigation." | 1.62 | Hyperglycemic conditions proliferate triple negative breast cancer cells: role of ornithine decarboxylase. ( Capellen, CC; Casero, RA; Chandra, S; Dunworth, M; Morwitzer, MJ; Ortega-Rodas, J; Tofilau, HMN, 2021) |
| "MCF-7 human breast carcinoma cells were transfected with tetracycline-regulated (Tet-off) SSAT human cDNA or murine gene." | 1.31 | Effects of conditional overexpression of spermidine/spermine N1-acetyltransferase on polyamine pool dynamics, cell growth, and sensitivity to polyamine analogs. ( Diegelman, P; Gan, G; Halmekyto, M; Janne, J; Kramer, DL; Porter, CW; Vujcic, S, 2000) |
| "Putrescine transport was inhibited by 70% by decreasing extracellular pH from 7." | 1.29 | Inorganic cation dependence of putrescine and spermidine transport in human breast cancer cells. ( Lessard, M; Poulin, R; Zhao, C, 1995) |
| " A dose-response curve was developed for each interferon in which the maximum dose applied gave at least 30% growth inhibition of control values after 96-128 h of continuous exposure." | 1.27 | The in vitro interaction of alpha-difluoromethyl ornithine (DFMO) and several interferons on human cell lines. ( Harvey, HA; Leitzel, KE; Lipton, A; Pegg, AE; Wolf, LM, 1985) |
| "In the present study human breast cancers were analysed for the presence of monoacetylated polyamines because N1-acetylspermidine is selectively elevated in human colorectal cancers." | 1.27 | Elevation of monoacetylated polyamines in human breast cancers. ( Kingsnorth, AN; Wallace, HM, 1985) |
| "In addition, the localized solid breast carcinoma, with non-proven metastases, did not provoke an increase in polyamine excretion." | 1.26 | Levels of polyamines and nucleic acids in human breast carcinoma. ( Cecco, L; Cerra, M; Romano, M, 1981) |
| "There were 105 patients with these tumors; 319 polyamine determinations were obtained from this subset of patients." | 1.26 | Further evidence for the use of polyamines as biochemical markers for malignant tumors. ( Beal, SL; Horn, Y; Lubich, WP; Marton, LJ; Spigel, L; Walach, N, 1982) |
| "All 6 patients with localized malignant tumors had elevated urinary polyamine levels." | 1.25 | Urinary polyamine levels in human cancer. ( Kessler, GF; Lipton, A; Sheehan, LM, 1975) |
| "Patients with breast carcinoma were screened for abnormal concentrations of CEA, HCG, putrescine, spermidine, spermine, pseudouridine, N2, N2-dimethylguanosine, and 1-methylinosine." | 1.25 | Biological markers in breast carcinoma. I. Incidence of abnormalities of CEA, HCG, three polyamines, and three minor nucleosides. ( Ahmann, D; Gehrke, CW; Hansen, H; Snyder, J; Tormey, DC; Waalkes, TP; Zumwatt, RW, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (42.31) | 18.7374 |
| 1990's | 14 (26.92) | 18.2507 |
| 2000's | 10 (19.23) | 29.6817 |
| 2010's | 1 (1.92) | 24.3611 |
| 2020's | 5 (9.62) | 2.80 |
| Authors | Studies |
|---|---|
| Capellen, CC | 1 |
| Ortega-Rodas, J | 1 |
| Morwitzer, MJ | 1 |
| Tofilau, HMN | 1 |
| Dunworth, M | 1 |
| Casero, RA | 1 |
| Chandra, S | 1 |
| Akinyele, O | 1 |
| Wallace, HM | 4 |
| Lores, S | 1 |
| Gámez-Chiachio, M | 1 |
| Cascallar, M | 1 |
| Ramos-Nebot, C | 1 |
| Hurtado, P | 1 |
| Alijas, S | 1 |
| López López, R | 1 |
| Piñeiro, R | 1 |
| Moreno-Bueno, G | 1 |
| de la Fuente, M | 1 |
| Chow, LWC | 1 |
| Wong, KL | 1 |
| Shiao, LR | 1 |
| Wu, KC | 1 |
| Leung, YM | 1 |
| Shukla, RP | 1 |
| Urandur, S | 1 |
| Banala, VT | 1 |
| Marwaha, D | 1 |
| Gautam, S | 1 |
| Rai, N | 1 |
| Singh, N | 1 |
| Tiwari, P | 1 |
| Shukla, P | 1 |
| Mishra, PR | 1 |
| Gupta, ED | 1 |
| Pachauri, M | 1 |
| Ghosh, PC | 1 |
| Rajam, MV | 1 |
| Byun, JA | 1 |
| Choi, MH | 1 |
| Moon, MH | 1 |
| Kong, G | 1 |
| Chul Chung, B | 1 |
| Christopher, SA | 1 |
| Diegelman, P | 2 |
| Porter, CW | 2 |
| Kruger, WD | 1 |
| Zaletok, S | 1 |
| Alexandrova, N | 1 |
| Berdynskykh, N | 1 |
| Ignatenko, N | 1 |
| Gogol, S | 1 |
| Orlovsky, O | 1 |
| Tregubova, N | 1 |
| Gerner, E | 1 |
| Chekhun, V | 1 |
| Manni, A | 8 |
| Washington, S | 2 |
| Mauger, D | 2 |
| Hackett, DA | 1 |
| Verderame, MF | 2 |
| Wang, JF | 1 |
| Su, RB | 1 |
| Wu, N | 1 |
| Xu, B | 1 |
| Lu, XQ | 1 |
| Liu, Y | 1 |
| Li, J | 1 |
| Gervais, A | 1 |
| Levêque, J | 1 |
| Bouet-Toussaint, F | 1 |
| Burtin, F | 1 |
| Lesimple, T | 1 |
| Sulpice, L | 1 |
| Patard, JJ | 1 |
| Genetet, N | 1 |
| Catros-Quemener, V | 1 |
| Lin, PH | 1 |
| Pan, WC | 1 |
| Kang, YW | 1 |
| Chen, YL | 1 |
| Lin, CH | 1 |
| Lee, MC | 1 |
| Chou, YH | 1 |
| Nakamura, J | 1 |
| Hu, X | 1 |
| Romano, M | 1 |
| Cecco, L | 1 |
| Cerra, M | 1 |
| Kingsnorth, AN | 2 |
| Bundred, NJ | 1 |
| Dixon, JM | 1 |
| Horn, Y | 2 |
| Beal, SL | 1 |
| Walach, N | 1 |
| Lubich, WP | 1 |
| Spigel, L | 2 |
| Marton, LJ | 2 |
| Tormey, DC | 4 |
| Waalkes, TP | 4 |
| Kuo, KC | 1 |
| Gehrke, CW | 3 |
| Nissen, E | 1 |
| Dettmer, R | 1 |
| Fiedler, D | 1 |
| Bodammer, M | 1 |
| Poulin, R | 4 |
| Lessard, M | 2 |
| Zhao, C | 3 |
| Nicoll, KM | 1 |
| McLean, M | 1 |
| Igarashi, K | 1 |
| Koga, K | 1 |
| He, Y | 1 |
| Shimogori, T | 1 |
| Ekimoto, H | 1 |
| Kashiwagi, K | 1 |
| Shirahata, A | 2 |
| Singh, SM | 1 |
| Wechter, R | 1 |
| Wei, L | 1 |
| Heitjan, D | 1 |
| Demers, L | 5 |
| Thomas, T | 5 |
| Thomas, TJ | 2 |
| Huber, M | 1 |
| Pelletier, JG | 1 |
| Torossian, K | 1 |
| Dionne, P | 1 |
| Gamache, I | 1 |
| Charest-Gaudreault, R | 2 |
| Audette, M | 2 |
| Verma, S | 1 |
| Lu, B | 1 |
| Liang, X | 1 |
| Scott, GK | 1 |
| Chang, CH | 1 |
| Baldwin, MA | 1 |
| Benz, CC | 1 |
| Shah, N | 1 |
| Sigal, LH | 1 |
| O'Shaughnessy, JA | 1 |
| Demers, LM | 1 |
| Jones, SE | 1 |
| Arseneau, J | 1 |
| Khandelwal, P | 1 |
| George, T | 1 |
| Gersh, R | 1 |
| Vujcic, S | 1 |
| Halmekyto, M | 1 |
| Gan, G | 1 |
| Kramer, DL | 1 |
| Janne, J | 1 |
| Srinath, P | 1 |
| McQuarrie, SA | 1 |
| Suresh, MR | 1 |
| Lipton, A | 2 |
| Sheehan, LM | 1 |
| Kessler, GF | 1 |
| Woo, KB | 1 |
| Ahmann, DL | 1 |
| Oliverio, VT | 1 |
| Ahmann, D | 1 |
| Zumwatt, RW | 1 |
| Snyder, J | 1 |
| Hansen, H | 1 |
| Fleisher, JH | 1 |
| Russell, DH | 1 |
| Badger, B | 1 |
| Martel, J | 1 |
| Kim, I | 1 |
| Lynch, J | 1 |
| Glikman, PL | 1 |
| Bartholomew, M | 2 |
| Glikman, P | 1 |
| Trend, B | 1 |
| Butterfield, JR | 1 |
| Jänne, OA | 1 |
| Kiang, DT | 2 |
| Hoggard, N | 1 |
| Green, CD | 1 |
| Kendra, KL | 1 |
| Katzenellenbogen, BS | 1 |
| Inamdar, NA | 1 |
| Redkar, SL | 1 |
| Mittra, I | 1 |
| Damle, SR | 1 |
| Norman, JC | 1 |
| Puddefoot, JR | 1 |
| Anderson, E | 1 |
| Braunsberg, H | 1 |
| Solov'ev, IE | 1 |
| Iurzhenko, NN | 1 |
| Wolf, LM | 1 |
| Leitzel, KE | 1 |
| Pegg, AE | 1 |
| Harvey, HA | 1 |
| Nishioka, K | 1 |
| Romsdahl, MM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Urinary Excretion of Acetylamantadine by Cancer Patients[NCT02277938] | 120 participants (Anticipated) | Observational | 2013-08-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for putrescine and Breast Cancer
| Article | Year |
|---|---|
A quantitative approach to determining disease response during therapy using multiple biologic markers: application to carcinoma of the breast.
Topics: Breast Neoplasms; Carcinoembryonic Antigen; Female; Guanosine; Humans; Inosine; Nucleosides; Polyami | 1978 |
Biochemical markers in cancer of the breast.
Topics: Breast Neoplasms; Cadaverine; Carcinoembryonic Antigen; Chorionic Gonadotropin; Cyclophosphamide; Do | 1976 |
2 trials available for putrescine and Breast Cancer
| Article | Year |
|---|---|
Alpha-difluoromethylornithine as treatment for metastatic breast cancer patients.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Eflornithine; Female; Humans; Middle Aged; Neo | 1999 |
Urinary polyamine levels in cancer patients treated with D,L-alpha-difluoromethylornithine, an inhibitor of polyamine biosynthesis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Evaluation; Eflornithine; Fem | 1989 |
48 other studies available for putrescine and Breast Cancer
| Article | Year |
|---|---|
Hyperglycemic conditions proliferate triple negative breast cancer cells: role of ornithine decarboxylase.
Topics: Breast Neoplasms; Eflornithine; Female; Humans; Hyperglycemia; Ornithine Decarboxylase; Ornithine De | 2021 |
Understanding the Polyamine and mTOR Pathway Interaction in Breast Cancer Cell Growth.
Topics: Breast Neoplasms; Female; Humans; Mechanistic Target of Rapamycin Complex 1; Phosphatidylinositol 3- | 2022 |
Effectiveness of a novel gene nanotherapy based on putrescine for cancer treatment.
Topics: Animals; Breast Neoplasms; Cell Cycle; Cell Death; Cell Line, Tumor; Female; Humans; Mice; Neoplasms | 2023 |
Polyamine stimulation perturbs intracellular Ca2+ homeostasis and decreases viability of breast cancer BT474 cells.
Topics: Breast Neoplasms; Calcium; Cell Line, Tumor; Cell Proliferation; Cell Survival; Endoplasmic Reticulu | 2020 |
Development of putrescine anchored nano-crystalsomes bearing doxorubicin and oleanolic acid: deciphering their role in inhibiting metastatic breast cancer.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Humans; Mice; Mice, Inbred BALB C; Oleanol | 2021 |
Targeting polyamine biosynthetic pathway through RNAi causes the abrogation of MCF 7 breast cancer cell line.
Topics: Adenosylmethionine Decarboxylase; Apoptosis; Breast Neoplasms; Cell Differentiation; Cell Division; | 2016 |
Serum polyamines in pre- and post-operative patients with breast cancer corrected by menopausal status.
Topics: Adult; Aged; Breast Neoplasms; Chromatography, Liquid; Female; Humans; Mass Spectrometry; Menopause; | 2009 |
Methylthioadenosine phosphorylase, a gene frequently codeleted with p16(cdkN2a/ARF), acts as a tumor suppressor in a breast cancer cell line.
Topics: Biogenic Polyamines; Breast Neoplasms; Gene Deletion; Genes, p16; Genes, Tumor Suppressor; Humans; P | 2002 |
Role of polyamines in the function of nuclear transcription factor NF-kappaB in breast cancer cells.
Topics: Animals; Blotting, Western; Breast Neoplasms; Carcinoma 256, Walker; Cell Line, Tumor; Cell Nucleus; | 2004 |
Cellular mechanisms mediating the anti-invasive properties of the ornithine decarboxylase inhibitor alpha-difluoromethylornithine (DFMO) in human breast cancer cells.
Topics: Breast Neoplasms; Eflornithine; Enzyme Inhibitors; Flavonoids; Hepatocyte Growth Factor; Humans; Mit | 2004 |
Inhibitory effect of agmatine on proliferation of tumor cells by modulation of polyamine metabolism.
Topics: Agmatine; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Humans; L-Lactate Dehydro | 2005 |
Dendritic cells are defective in breast cancer patients: a potential role for polyamine in this immunodeficiency.
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, No | 2005 |
Effects of naphthalene quinonoids on the induction of oxidative DNA damage and cytotoxicity in calf thymus DNA and in human cultured cells.
Topics: Aldehydes; Animals; Breast Neoplasms; Cattle; Cell Line, Tumor; Cell Survival; Cells, Cultured; DNA; | 2005 |
Interaction between Polyamines and the Mitogen-Activated Protein Kinase Pathway in the Regulation of Cell Cycle Variables in Breast Cancer Cells.
Topics: Breast Neoplasms; Butadienes; Calcium-Binding Proteins; Cell Cycle; Cell Growth Processes; Cell Line | 2005 |
Levels of polyamines and nucleic acids in human breast carcinoma.
Topics: Adult; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; DNA, Neoplasm; Female; Humans; Mid | 1981 |
Polyamines in breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Female; Humans; Lymphatic Metastasis; Mastectomy; Middle Aged; Neopla | 1984 |
Further evidence for the use of polyamines as biochemical markers for malignant tumors.
Topics: Breast Neoplasms; Clinical Laboratory Techniques; Female; Genital Neoplasms, Female; Humans; Male; N | 1982 |
Biologic markers in breast carcinoma: clinical correlations with urinary polyamines.
Topics: Breast Neoplasms; Cadaverine; Female; Humans; Polyamines; Prognosis; Putrescine; Spermidine; Spermin | 1980 |
[Polyamines and their significance for control of cancer chemotherapy (author's transl)].
Topics: Breast Neoplasms; Carubicin; Cyclophosphamide; Fluorouracil; Humans; Methotrexate; Mitolactol; Polya | 1980 |
Inorganic cation dependence of putrescine and spermidine transport in human breast cancer cells.
Topics: Biological Transport; Breast Neoplasms; Calcimycin; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazo | 1995 |
Uptake of putrescine by human breast cancer cells.
Topics: Biological Transport; Breast Neoplasms; Cell Line; Humans; Kinetics; Putrescine; Temperature; Time F | 1994 |
Inhibition of the growth of various human and mouse tumor cells by 1,15-bis(ethylamino)-4,8,12-triazapentadecane.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Breast Neoplas | 1995 |
Hormonal and feedback regulation of putrescine and spermidine transport in human breast cancer cells.
Topics: Biological Transport; Breast Neoplasms; Cell Division; Cell Line; Cycloheximide; Drug Synergism; Efl | 1995 |
Phenotypic features of breast cancer cells overexpressing ornithine-decarboxylase.
Topics: Breast Neoplasms; Clone Cells; Eflornithine; Ornithine Decarboxylase; Phenotype; Polyamines; Putresc | 1995 |
Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: therapeutic implications.
Topics: Breast Neoplasms; Cell Division; Cell Line; Eflornithine; Estradiol; Female; Flow Cytometry; G1 Phas | 1994 |
2,2'-Dithiobis(N-ethyl-spermine-5-carboxamide) is a high affinity, membrane-impermeant antagonist of the mammalian polyamine transport system.
Topics: Animals; Breast Neoplasms; Cell Division; Cell Membrane; CHO Cells; Cricetinae; Cycloheximide; Cyste | 1996 |
Dependence of mammalian putrescine and spermidine transport on plasma-membrane potential: identification of an amiloride binding site on the putrescine carrier.
Topics: Amiloride; Animals; Binding Sites; Biological Transport; Breast Neoplasms; Carbonyl Cyanide m-Chloro | 1998 |
Polyamine inhibition of estrogen receptor (ER) DNA-binding and ligand-binding functions.
Topics: Breast; Breast Neoplasms; Cells, Cultured; DNA; Estradiol; Female; Humans; Polyamines; Putrescine; R | 1998 |
Activation of nuclear factor kappaB by polyamines in breast cancer cells.
Topics: Breast Neoplasms; Circular Dichroism; Female; Guanidines; Humans; NF-kappa B; Polyamines; Protein Co | 1999 |
Effects of conditional overexpression of spermidine/spermine N1-acetyltransferase on polyamine pool dynamics, cell growth, and sensitivity to polyamine analogs.
Topics: Acetylation; Acetyltransferases; Breast Neoplasms; Cell Division; Clone Cells; Doxycycline; Female; | 2000 |
Comparative uptake of polyamines by prostate and non-prostate cancer cell lines.
Topics: Animals; Breast Neoplasms; Carbon Radioisotopes; Humans; Male; Ornithine; Polyamines; Prostatic Neop | 2002 |
Urinary polyamine levels in human cancer.
Topics: Adenocarcinoma; Adenoma; Bone Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous | 1975 |
Biological markers in breast carcinoma. I. Incidence of abnormalities of CEA, HCG, three polyamines, and three minor nucleosides.
Topics: Breast Neoplasms; Carcinoembryonic Antigen; Chorionic Gonadotropin; Female; Guanosine; Humans; Inosi | 1975 |
Estimation of urinary diamines and polyamines by thin-layer chromatography.
Topics: Breast Neoplasms; Cadaverine; Chromatography, Thin Layer; Dansyl Compounds; Diamines; Humans; Melano | 1975 |
Role of polyamines in the growth of hormone-responsive and -resistant human breast cancer cells in nude mice.
Topics: Animals; Breast Neoplasms; Cell Division; Drug Resistance; Drug Screening Assays, Antitumor; Eflorni | 1992 |
Polyamine involvement in the secretion and action of TGF-alpha in hormone sensitive human breast cancer cells in culture.
Topics: Breast Neoplasms; Cell Division; Eflornithine; Estrogens; Humans; In Vitro Techniques; Neoplasms, Ho | 1991 |
Polyamine involvement in basal and estradiol-stimulated insulin-like growth factor I secretion and action in breast cancer cells in culture.
Topics: Antibodies, Monoclonal; Breast Neoplasms; Cell Transformation, Neoplastic; Eflornithine; Estradiol; | 1990 |
Polyamine involvement in the growth of hormone-responsive and -resistant human breast cancer cells in culture.
Topics: Biogenic Polyamines; Breast Neoplasms; Cell Count; Dose-Response Relationship, Drug; Eflornithine; F | 1989 |
Regulation of ornithine decarboxylase gene expression in MCF-7 breast cancer cells by antiestrogens.
Topics: Blotting, Northern; Breast Neoplasms; Cell Line; Estrogen Antagonists; Female; Gene Expression Regul | 1989 |
Polyamines and growth regulation of cultured human breast cancer cells by 17 beta-oestradiol.
Topics: Breast Neoplasms; Cell Division; Cell Line; Eflornithine; Estradiol; Humans; Insulin; Ornithine; Orn | 1986 |
An evaluation of the involvement of polyamines in modulating MCF-7 human breast cancer cell proliferation and progesterone receptor levels by estrogen and antiestrogen.
Topics: Breast Neoplasms; Cell Division; Cell Line; Eflornithine; Estradiol; Humans; Neoplasms, Hormone-Depe | 1987 |
Additive growth-inhibitory effects of DL-alpha-difluoromethylornithine and antiestrogens on MCF-7 breast cancer cell line.
Topics: Breast Neoplasms; Dose-Response Relationship, Drug; Drug Synergism; Eflornithine; Estrogen Antagonis | 1987 |
Clinical significance of serum spermine in breast cancer.
Topics: Adult; Breast Diseases; Breast Neoplasms; Carcinoembryonic Antigen; Female; Glucose-6-Phosphate Isom | 1988 |
Relationships between polyamine, deoxyribonucleic acid and oestrogen receptor binding site concentrations in human breast tumours.
Topics: Breast Neoplasms; DNA, Neoplasm; Female; Humans; Polyamines; Putrescine; Receptors, Estrogen; Spermi | 1988 |
[Urinary polyamines and hydroxyproline in patients with breast cancer].
Topics: Adult; Aged; Breast Neoplasms; Female; Humans; Hydroxyproline; Middle Aged; Neoplasm Staging; Putres | 1986 |
The in vitro interaction of alpha-difluoromethyl ornithine (DFMO) and several interferons on human cell lines.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Drug Interactions; | 1985 |
Elevation of monoacetylated polyamines in human breast cancers.
Topics: Breast Neoplasms; Female; Humans; Polyamines; Prognosis; Putrescine; Spermidine; Spermine | 1985 |
Elevation of putrescine and spermidine in sera of patients with solid tumors.
Topics: Autoanalysis; Breast Neoplasms; Cadaverine; Carbon Radioisotopes; Carcinoma; Chromatography, Ion Exc | 1974 |