putrescine has been researched along with Benign Neoplasms in 68 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The levels of polyamines (putrescine, spermidine and spermine) in erythrocytes and plasma were studied using Cloudman S-91 melanoma grown in the lungs of DBA/2 mice." | 3.66 | Raised polyamines in erythrocytes from melanoma-bearing mice and patients with solid tumours. ( Nishioka, K; Takami, H, 1980) |
| "The polyamines--putrescine, spermidine and spermine--are present in elevated concentrations in rapidly growing cell lines and in several neoplasms." | 3.66 | Imaging of canine tumors with 11C-methylputrescine. ( Fair, WR; Miller, TR; Siegel, BA; Smith, EK; Welch, MJ, 1978) |
| "Putrescine plays a very important role in the regulation of division, differentiation and maturation of cells as well as apoptosis." | 2.50 | [The importance of putrescine in the human body]. ( Lachowski, M; Zdrojewicz, Z, 2014) |
| "Two third of cancers generally show elevated urinary excretion of polyamines." | 2.36 | [Polyamines and malignant diseases (author's transl)]. ( Boublil, JL; Cambon, P; Cassuto, JP; Krebs, BP; Lalanne, CM; Lesbats, G; Milano, G; Namer, M; Schneider, M; Viguier, E, 1980) |
| "Cancers are a broad spectrum of diseases in which there are altered growth fractions and cell-turnover fractions, and therefore cancer chemotherapeutic agents have been developed to take tumor kinetics into account." | 2.36 | Clinical relevance of polyamines as biochemical markers of tumor kinetics. ( Russell, DH, 1977) |
| "Gene therapy has long been proposed for cancer treatment." | 1.91 | Effectiveness of a novel gene nanotherapy based on putrescine for cancer treatment. ( Alijas, S; Cascallar, M; de la Fuente, M; Gámez-Chiachio, M; Hurtado, P; López López, R; Lores, S; Moreno-Bueno, G; Piñeiro, R; Ramos-Nebot, C, 2023) |
| "Metabolic reprograming is a hallmark of cancer, and the polyamine metabolic network is dysregulated in many cancers." | 1.56 | The rational discovery of multipurpose inhibitors of the ornithine decarboxylase. ( Chai, X; He, M; Li, B; Liu, S; Ma, H; Pan, J; Wang, J; Wang, Y; Zhan, J, 2020) |
| "To develop effective strategies in cancer chemoprevention, an increased understanding of endogenous biochemical mediators that block metastatic processes is critically needed." | 1.37 | Cellular diamine levels in cancer chemoprevention: modulation by ibuprofen and membrane plasmalogens. ( Goodenowe, DB; Khan, MA; Smith, T; Wood, PL, 2011) |
| " However, the development of lethal toxic effects due to prevention of spermine degradation is a considerable disadvantage of the compound." | 1.33 | Cytotoxicity of the polyamine oxidase inactivator MDL 72527 to cancer cells: comparison with a saturated structural analogue. ( Gossé, F; Raul, F; Renault, J; Roussi, S; Seiler, N, 2005) |
| "6 mumol after dosing with 1500 mg/day for 4 weeks, the levels after each treatment schedule being sufficient to inhibit ODC as demonstrated by increases in the urinary excretion of decarboxylated S-adenosylmethionine (dc-SAM)." | 1.28 | Phase I study of methylacetylenic putrescine, an inhibitor of polyamine biosynthesis. ( Cornbleet, MA; Haegele, KD; Joder-Ohlenbusch, AM; Kingsnorth, A; Smyth, JF; Tell, GP, 1989) |
| "This method is applied to cancer patients treated by cytotoxic chemotherapy with or without difluoromethylornithine (DFMO)." | 1.27 | Determination of free and total polyamines in human serum and urine by ion-pairing high-performance liquid chromatography using a radial compression module. Application to blood polyamine determination in cancer patients treated or not treated with an orn ( Belleville, F; Brossat, B; Metz, R; Nabet, P; Straczek, J, 1983) |
| "There were 105 patients with these tumors; 319 polyamine determinations were obtained from this subset of patients." | 1.26 | Further evidence for the use of polyamines as biochemical markers for malignant tumors. ( Beal, SL; Horn, Y; Lubich, WP; Marton, LJ; Spigel, L; Walach, N, 1982) |
| "The development of human tumors is accompanied very often by tumor-associated phenomena such as production of tumor-derived substances, production of certian substances in response to the tumor or immunological reactions." | 1.26 | Biological markers of human tumors and monitoring of cancer treatment. ( Nissen, E; Tanneberger, S; Ziegenbein, R, 1979) |
| "All 6 patients with localized malignant tumors had elevated urinary polyamine levels." | 1.25 | Urinary polyamine levels in human cancer. ( Kessler, GF; Lipton, A; Sheehan, LM, 1975) |
| "In 37 (88%) of 42 cancer patients and in 24 (44%) of 54 patients with various nonmalignant diseases, increased amounts of polyamines were found in the urine." | 1.25 | Polyamine excretion in the urine of cancer patients. ( Chayen, R; Dreyfuss, F; Dreyfuss, G; Dvir, R; Ratan, J, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (67.65) | 18.7374 |
| 1990's | 4 (5.88) | 18.2507 |
| 2000's | 7 (10.29) | 29.6817 |
| 2010's | 5 (7.35) | 24.3611 |
| 2020's | 6 (8.82) | 2.80 |
| Authors | Studies |
|---|---|
| de Medina, P | 1 |
| Paillasse, MR | 1 |
| Payré, B | 1 |
| Silvente-Poirot, S | 1 |
| Poirot, M | 1 |
| Holbert, CE | 1 |
| Cullen, MT | 1 |
| Casero, RA | 2 |
| Stewart, TM | 1 |
| Lu, B | 1 |
| Wang, L | 1 |
| Ran, X | 1 |
| Tang, H | 1 |
| Cao, D | 1 |
| Lores, S | 1 |
| Gámez-Chiachio, M | 1 |
| Cascallar, M | 1 |
| Ramos-Nebot, C | 1 |
| Hurtado, P | 1 |
| Alijas, S | 1 |
| López López, R | 1 |
| Piñeiro, R | 1 |
| Moreno-Bueno, G | 1 |
| de la Fuente, M | 1 |
| Larenkov, A | 1 |
| Rakhimov, M | 1 |
| Lunyova, K | 1 |
| Klementyeva, O | 1 |
| Maruk, A | 1 |
| Machulkin, A | 1 |
| Chai, X | 1 |
| Zhan, J | 1 |
| Pan, J | 1 |
| He, M | 1 |
| Li, B | 1 |
| Wang, J | 1 |
| Ma, H | 1 |
| Wang, Y | 1 |
| Liu, S | 1 |
| Amin, M | 1 |
| Tang, S | 1 |
| Shalamanova, L | 1 |
| Taylor, RL | 1 |
| Wylie, S | 1 |
| Abdullah, BM | 1 |
| Whitehead, KA | 1 |
| Ramani, D | 1 |
| De Bandt, JP | 1 |
| Cynober, L | 1 |
| Zdrojewicz, Z | 1 |
| Lachowski, M | 1 |
| Scozzafava, A | 1 |
| Supuran, CT | 1 |
| Carta, F | 1 |
| Saad, JS | 1 |
| Benedetti, M | 1 |
| Natile, G | 1 |
| Marzilli, LG | 1 |
| Wood, PL | 1 |
| Khan, MA | 1 |
| Smith, T | 1 |
| Goodenowe, DB | 1 |
| Martin, B | 1 |
| Possémé, F | 1 |
| Le Barbier, C | 1 |
| Carreaux, F | 1 |
| Carboni, B | 1 |
| Seiler, N | 2 |
| Moulinoux, JP | 1 |
| Delcros, JG | 1 |
| DELPIANO, E | 1 |
| LISI, B | 1 |
| PASQUALUCCI, E | 1 |
| Huang, Y | 1 |
| Pledgie, A | 1 |
| Davidson, NE | 1 |
| Renault, J | 1 |
| Gossé, F | 1 |
| Roussi, S | 1 |
| Raul, F | 2 |
| Pegg, AE | 1 |
| Feith, DJ | 1 |
| Zoumas-Morse, C | 1 |
| Rock, CL | 1 |
| Quintana, EL | 1 |
| Neuhouser, ML | 1 |
| Gerner, EW | 1 |
| Meyskens, FL | 1 |
| Tabor, CW | 1 |
| Tabor, H | 1 |
| Kersten, W | 1 |
| Russell, DH | 8 |
| Scalabrino, G | 1 |
| Ferioli, ME | 1 |
| Matsuzaki, S | 1 |
| Takenoshita, S | 1 |
| Filipović, N | 1 |
| Borcić, N | 1 |
| Hotić, A | 1 |
| Kecman, G | 1 |
| Hadziabdić, E | 1 |
| Jusufović, D | 1 |
| Brossat, B | 1 |
| Straczek, J | 1 |
| Belleville, F | 1 |
| Nabet, P | 1 |
| Metz, R | 1 |
| Wang, Z | 1 |
| Dai, YP | 1 |
| Yu, SY | 1 |
| Yao, XR | 1 |
| Zou, XQ | 1 |
| Shinpo, K | 2 |
| Fujita, K | 3 |
| Maruta, K | 3 |
| Teradaira, R | 2 |
| Nagatsu, T | 3 |
| Matsumoto, T | 1 |
| Suzuki, O | 1 |
| Katsumata, Y | 1 |
| Oya, M | 1 |
| Nimura, Y | 1 |
| Akita, M | 1 |
| Hattori, T | 1 |
| Szeszko, A | 1 |
| Lutz, W | 1 |
| Milano, G | 2 |
| Viguier, E | 2 |
| Cassuto, JP | 2 |
| Schneider, M | 2 |
| Namer, M | 1 |
| Boublil, JL | 2 |
| Lesbats, G | 1 |
| Cambon, P | 2 |
| Krebs, BP | 1 |
| Lalanne, CM | 2 |
| Horn, Y | 1 |
| Beal, SL | 1 |
| Walach, N | 1 |
| Lubich, WP | 1 |
| Spigel, L | 1 |
| Marton, LJ | 2 |
| Sadananda, B | 1 |
| Natarajan, RS | 1 |
| Vittal, C | 1 |
| Kalyankar, GD | 1 |
| Abdel-Monem, MM | 1 |
| Merdink, JL | 1 |
| Pastorini, P | 1 |
| Nakamura, M | 1 |
| Takami, H | 2 |
| Nishioka, K | 3 |
| Bardocz, S | 1 |
| Khuhawar, MY | 1 |
| Memon, AA | 1 |
| Jaipal, PD | 1 |
| Bhanger, MI | 1 |
| Lipton, A | 2 |
| Sheehan, LM | 1 |
| Kessler, GF | 1 |
| Durie, BG | 3 |
| Salmon, SE | 3 |
| Romsdahl, MM | 2 |
| Tanneberger, S | 1 |
| Nissen, E | 1 |
| Ziegenbein, R | 1 |
| Roch, AM | 1 |
| Quash, GA | 1 |
| Ripoll, JP | 1 |
| Saez, S | 1 |
| Williams-Ashman, HG | 1 |
| Canellakis, ZN | 1 |
| Saeki, Y | 1 |
| Uehara, N | 1 |
| Shirakawa, S | 1 |
| Rosenblum, MG | 2 |
| Miller, TR | 1 |
| Siegel, BA | 1 |
| Fair, WR | 1 |
| Smith, EK | 1 |
| Welch, MJ | 1 |
| Sheehan, L | 1 |
| Mortel, R | 1 |
| Harvey, HA | 1 |
| Tsuji, M | 1 |
| Nakajima, T | 1 |
| Sano, I | 1 |
| Dreyfuss, F | 1 |
| Chayen, R | 1 |
| Dreyfuss, G | 1 |
| Dvir, R | 1 |
| Ratan, J | 1 |
| Bartos, D | 1 |
| Campbell, RA | 1 |
| Bartos, F | 1 |
| Grettie, DP | 1 |
| Ito, M | 1 |
| Senba, H | 1 |
| Kobayashi, Y | 1 |
| Yoshikawa, T | 1 |
| Watanabe, N | 1 |
| Jiang, XC | 1 |
| Cornbleet, MA | 1 |
| Kingsnorth, A | 1 |
| Tell, GP | 1 |
| Haegele, KD | 1 |
| Joder-Ohlenbusch, AM | 1 |
| Smyth, JF | 1 |
| Mashige, F | 1 |
| Tanaka, N | 1 |
| Murakami, T | 1 |
| Shimosaka, H | 1 |
| Kamei, S | 1 |
| Ohkubo, A | 1 |
| Kovach, JS | 1 |
| Svingen, PA | 1 |
| Seidenfeld, J | 1 |
| Kallistratos, G | 1 |
| Levy, CC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| TArgeting Type 1 Diabetes Using POLyamines (TADPOL): A Randomized, Double-Masked, Placebo-Controlled Phase 2 Study to Evaluate the Efficacy and Safety of Difluoromethylornithine (DFMO) to Preserve Insulin Production in Type 1 Diabetes[NCT05594563] | Phase 2 | 70 participants (Anticipated) | Interventional | 2023-03-14 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 reviews available for putrescine and Benign Neoplasms
| Article | Year |
|---|---|
Polyamines in cancer: integrating organismal metabolism and antitumour immunity.
Topics: Animals; Humans; Mammals; Neoplasms; Polyamines; Putrescine; Spermidine; Spermine; Tumor Microenviro | 2022 |
Recent Advances in Fluorescent Methods for Polyamine Detection and the Polyamine Suppressing Strategy in Tumor Treatment.
Topics: Humans; Neoplasms; Polyamines; Putrescine; Spermidine; Spermine | 2022 |
Polyamine biomarkers as indicators of human disease.
Topics: Acrolein; Alzheimer Disease; Apoptosis; Biomarkers; Biotransformation; Cadaverine; Cell Movement; Hu | 2021 |
Aliphatic polyamines in physiology and diseases.
Topics: Agmatine; Animals; Disease Models, Animal; Humans; Neoplasms; Ornithine; Putrescine; Spermidine; Spe | 2014 |
[The importance of putrescine in the human body].
Topics: Apoptosis; Cell Differentiation; Cell Division; Cell Membrane; Eflornithine; Hirsutism; Homeostasis; | 2014 |
Polyamines and α-Carbonic Anhydrases.
Topics: Antineoplastic Agents; Biological Products; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Coum | 2016 |
Molecular mechanisms of polyamine analogs in cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Eflornithine; Humans; Molecular Conformation; Neoplasms; | 2005 |
Polyamines.
Topics: Adenosylmethionine Decarboxylase; Animals; Arginase; Aspergillus nidulans; Carboxy-Lyases; Cloning, | 1984 |
[Tumor therapy: control of results by analysis of polyamines?].
Topics: Brain Neoplasms; Enzyme Induction; Evaluation Studies as Topic; Gonadal Steroid Hormones; Humans; Le | 1983 |
Clinical relevance of polyamines.
Topics: Animals; Cadaverine; Cystic Fibrosis; Diamines; Female; Growth Disorders; Humans; Kidney Failure, Ch | 1983 |
Polyamines in mammalian ageing: an oncological problem, too? A review.
Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Humans; Male; Neoplasms; Ornithine Decarboxylase; | 1984 |
[Polyamine analysis of blood, tissue and gastric juice and its clinical significance. II. Analysis of tissue polyamines and their derivatives and their significance].
Topics: Humans; Neoplasms; Polyamines; Putrescine; Spermidine; Spermine; Tissue Distribution | 1984 |
[Polyamines and malignant diseases (author's transl)].
Topics: Cell Division; Humans; Kinetics; Neoplasms; Polyamines; Putrescine; Spermidine; Spermine | 1980 |
The role of dietary polyamines.
Topics: Cadaverine; Cell Division; Diet; Digestive System; DNA; Eflornithine; Humans; Neoplasms; Protein Bio | 1993 |
Clinical relevance of polyamines as biochemical markers of tumor kinetics.
Topics: Animals; Humans; Kinetics; Neoplasms; Neoplasms, Experimental; Polyamines; Putrescine; Rats; Spermid | 1977 |
The roles of the polyamines, putrescine, spermidine, and spermine in normal and malignant tissues.
Topics: Animals; Carboxy-Lyases; DNA-Directed RNA Polymerases; Drug Synergism; Humans; Neoplasms; Ornithine; | 1973 |
52 other studies available for putrescine and Benign Neoplasms
| Article | Year |
|---|---|
Synthesis of new alkylaminooxysterols with potent cell differentiating activities: identification of leads for the treatment of cancer and neurodegenerative diseases.
Topics: Amines; Animals; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cholestanols; Dendrites; Dru | 2009 |
Effectiveness of a novel gene nanotherapy based on putrescine for cancer treatment.
Topics: Animals; Breast Neoplasms; Cell Cycle; Cell Death; Cell Line, Tumor; Female; Humans; Mice; Neoplasms | 2023 |
Pharmacokinetic Properties of
Topics: A549 Cells; Acetates; Animals; Folic Acid; Folic Acid Transporters; Gallium Radioisotopes; HCT116 Ce | 2020 |
The rational discovery of multipurpose inhibitors of the ornithine decarboxylase.
Topics: A549 Cells; Animals; Antineoplastic Agents; Biocatalysis; Cell Survival; Female; High-Throughput Scr | 2020 |
NMR studies of models having the Pt(d(GpG)) 17-membered macrocyclic ring formed in DNA by platinum anticancer drugs: Pt complexes with bulky chiral diamine ligands.
Topics: Antineoplastic Agents; Circular Dichroism; Cisplatin; Dinucleoside Phosphates; DNA; DNA Adducts; Gua | 2011 |
Cellular diamine levels in cancer chemoprevention: modulation by ibuprofen and membrane plasmalogens.
Topics: Amino Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cadaverine; Cell Membrane; CHO Cells; | 2011 |
(Z)-1,4-diamino-2-butene as a vector of boron, fluorine, or iodine for cancer therapy and imaging: synthesis and biological evaluation.
Topics: Animals; Biological Transport; Boron; Cell Division; CHO Cells; Cricetinae; Dose-Response Relationsh | 2002 |
[THE DIAMINOPROPYL-PUTRESCIN REACTION (TOKUOKA'S SPERMINE REACTION) IN NEOPLASMS AND IN VARIOUS BLOOD DISEASES].
Topics: Blood Chemical Analysis; Hematologic Diseases; Hematology; Humans; Neoplasms; Putrescine; Spermine | 1963 |
Cytotoxicity of the polyamine oxidase inactivator MDL 72527 to cancer cells: comparison with a saturated structural analogue.
Topics: Animals; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationsh | 2005 |
Polyamines and neoplastic growth.
Topics: Cell Division; Homeostasis; Humans; Neoplasms; Ornithine Decarboxylase; Polyamines; Putrescine | 2007 |
Revival of 2-(difluoromethyl)ornithine (DFMO), an inhibitor of polyamine biosynthesis, as a cancer chemopreventive agent.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Cell Division; Cell Line, Tumor; Eflornithi | 2007 |
Development of a polyamine database for assessing dietary intake.
Topics: Beverages; Databases, Factual; Food Analysis; Fruit; Humans; Meat; Neoplasms; Pisum sativum; Polyami | 2007 |
[Polyamines as biochemical markers of malignant tumors and the efficacy of chemotherapy].
Topics: Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Humans; Middle Aged; Neoplasms; Polyamines; P | 1983 |
Determination of free and total polyamines in human serum and urine by ion-pairing high-performance liquid chromatography using a radial compression module. Application to blood polyamine determination in cancer patients treated or not treated with an orn
Topics: Aged; Cadaverine; Chromatography, High Pressure Liquid; Eflornithine; Female; Fluorescence; Humans; | 1983 |
[Significance of polarographic analysis of urine P-wave substance in malignancy diagnosis (author's transl)].
Topics: Humans; Neoplasms; Polarography; Putrescine | 1981 |
Comparative measurements of urinary polyamines in early morning and 24-hour urine specimens.
Topics: Circadian Rhythm; Creatinine; Humans; Neoplasms; Polyamines; Putrescine; Spermidine | 1983 |
A fluorometric assay for total diamines in human urine using human placental diamine oxidase.
Topics: Amine Oxidase (Copper-Containing); Cadaverine; Chromatography, Ion Exchange; Diamines; Female; Human | 1981 |
[Analytical and clinical aspects of polyamines].
Topics: Humans; Kidney Diseases; Neoplasms; Putrescine; Spermidine; Spermine | 1983 |
Further evidence for the use of polyamines as biochemical markers for malignant tumors.
Topics: Breast Neoplasms; Clinical Laboratory Techniques; Female; Genital Neoplasms, Female; Humans; Male; N | 1982 |
Urinary polyamines in cancer.
Topics: Humans; Neoplasms; Putrescine; Spermidine; Spermine | 1980 |
Determination of monoacetyldiamines and -polyamines in urine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Dansyl Compounds; Humans; Neoplasms; Putrescine; Reference Val | 1981 |
The clinical value of urinary polyamine analyses in cancer patients.
Topics: Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Neoplasms; Polyamines; Putrescine | 1980 |
Improved analysis for urinary polyamines by use of high-voltage electrophoresis on paper.
Topics: Autoanalysis; Cadaverine; Electrophoresis, Paper; Histamine; Humans; Neoplasms; Polyamines; Putresci | 1980 |
Raised polyamines in erythrocytes from melanoma-bearing mice and patients with solid tumours.
Topics: Animals; Erythrocytes; Female; Humans; Male; Melanoma; Mice; Mice, Inbred DBA; Middle Aged; Neoplasm | 1980 |
Capillary gas chromatographic determination of putrescine and cadaverine in serum of cancer patients using trifluoroacetylacetone as derivatizing reagent.
Topics: Cadaverine; Case-Control Studies; Chromatography, Gas; Female; Humans; Indicators and Reagents; Male | 1999 |
Urinary polyamine levels in human cancer.
Topics: Adenocarcinoma; Adenoma; Bone Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous | 1975 |
Polyamines as predictors of success and failure in cancer chemotherapy.
Topics: Antineoplastic Agents; Humans; Models, Biological; Monitoring, Physiologic; Neoplasms; Polyamines; P | 1975 |
Polyamines in blood-cells as a cancer marker.
Topics: Female; Humans; Leukocytes; Male; Neoplasms; Plasma; Putrescine; Spermidine; Spermine | 1979 |
Biological markers of human tumors and monitoring of cancer treatment.
Topics: Alkaline Phosphatase; alpha-Fetoproteins; Bone Neoplasms; Carcinoembryonic Antigen; Choriocarcinoma; | 1979 |
Evidence for natural antibodies (IgG) to polyamines in human sera.
Topics: Antibody Specificity; Hemagglutination Inhibition Tests; Humans; Immunity, Innate; Immunoglobulin G; | 1979 |
Polyamines in mammalian biology and medicine.
Topics: Adenosylmethionine Decarboxylase; Animals; Isoelectric Point; Molecular Conformation; Neoplasms; Orn | 1979 |
Sensitive fluorimetric method for the determination of putrescine, spermidine and spermine by high-performance liquid chromatography and its application to human blood.
Topics: Chromatography, High Pressure Liquid; Dansyl Compounds; Erythrocytes; Humans; Neoplasms; Putrescine; | 1978 |
Metabolism of [14C]spermidine and [14C]putrescine in normal volunteers and in cancer patients.
Topics: Humans; Metabolic Clearance Rate; Neoplasms; Putrescine; Spermidine | 1978 |
Imaging of canine tumors with 11C-methylputrescine.
Topics: Animals; Carbon Radioisotopes; Dog Diseases; Dogs; Methods; Neoplasms; Putrescine; Radionuclide Imag | 1978 |
Polyamines as markers of response and disease activity in cancer chemotherapy.
Topics: Antineoplastic Agents; Female; Humans; Male; Neoplasms; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Conjugation of radiolabeled polyamines in the rat.
Topics: Animals; Hepatectomy; Kidney; Liver; Male; Metabolic Clearance Rate; Neoplasms; Nephrectomy; Putresc | 1977 |
Polyamines as markers of response to chemotherapy of cancer.
Topics: Humans; Neoplasms; Putrescine; Spermidine; Spermine | 1977 |
Urinary polyamine levels in patients with localized malignancy.
Topics: Adolescent; Adult; Female; Gastrointestinal Neoplasms; Genital Neoplasms, Female; Humans; Lung Neopl | 1976 |
Putrescine, spermidine, N-acetylspermidine and spermine in the urine of patients with leukaemias and tumors.
Topics: Age Factors; Chromatography, Ion Exchange; Female; Humans; Leukemia; Male; Neoplasms; Putrescine; Se | 1975 |
Polyamine excretion in the urine of cancer patients.
Topics: Adult; Aged; Cadaverine; Female; Humans; Male; Middle Aged; Neoplasms; Polyamines; Putrescine; Sperm | 1975 |
Direct determination of polyamines in human serum by radioimmunoassay.
Topics: Animals; Cadaverine; Cross Reactions; Horses; Humans; Neoplasms; Polyamines; Putrescine; Rabbits; Ra | 1975 |
Urinary putrescine, spermidine, and spermine in human blood and solid cancers and in an experimental gastric tumor of rats.
Topics: Animals; Female; Humans; Leukemia; Lymphoma; Methylnitronitrosoguanidine; Neoplasms; Neoplasms, Expe | 1976 |
Tumor cytostasis mediated by LPS- or PSK-activated human plastic-adherent peripheral blood mononuclear cells.
Topics: Animals; Arginine; Cell Communication; Cell Cycle; Cells, Cultured; Cytotoxicity, Immunologic; Human | 1992 |
Determination of polyamines in urine of normal human and cancer patients by capillary gas chromatography.
Topics: Adolescent; Adult; Aged; Chromatography, Gas; Female; Humans; Male; Middle Aged; Neoplasms; Polyamin | 1990 |
Phase I study of methylacetylenic putrescine, an inhibitor of polyamine biosynthesis.
Topics: Adult; Aged; Alkynes; Antineoplastic Agents; Diamines; Drug Evaluation; Female; Humans; Male; Middle | 1989 |
Clinical usefulness of an enzymatic determination of total urinary polyamines, excluding cadaverine.
Topics: Adult; Cadaverine; Circadian Rhythm; Diamines; Female; Humans; Liver Diseases; Male; Methods; Neopla | 1988 |
Enhancement of the antiproliferative activity of human interferon by polyamine depletion.
Topics: Aspirin; Cell Division; Cell Line; Doxorubicin; Drug Synergism; Eflornithine; Humans; Indomethacin; | 1985 |
Effects of difluoromethylornithine on proliferation, polyamine content and plating efficiency of cultured human carcinoma cells.
Topics: Cell Division; Cell Line; Clone Cells; Eflornithine; Female; Humans; Kinetics; Neoplasms; Ornithine; | 1985 |
Polyamines.
Topics: Animals; Cell Differentiation; DNA-Directed RNA Polymerases; Humans; Mammals; Methylation; Neoplasms | 1973 |
[Inhibition of 3,4-benzopyrene-cancerogenesis in mice through putrescine].
Topics: Animals; Benzopyrenes; Female; Mice; Neoplasms; Putrescine | 1974 |
Elevation of putrescine and spermidine in sera of patients with solid tumors.
Topics: Autoanalysis; Breast Neoplasms; Cadaverine; Carbon Radioisotopes; Carcinoma; Chromatography, Ion Exc | 1974 |
Measurement of putrescine, spermidine, and spermine in physiological fluids by use of an amino acid analyzer.
Topics: Autoanalysis; Carbon Isotopes; Carcinoma, Squamous Cell; Chromatography, Ion Exchange; Humans; Lung | 1973 |