putrescine has been researched along with Benign Neoplasms, Brain in 56 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The polyamine metabolism of transplanted N-nitrosomethylurea-derived rat glioma was determined with radiolabeled putrescine used as a marker for malignancy." | 3.66 | Labeled putrescine as a probe in brain tumors. ( Brodie, JD; Cravioto, H; Flamm, ES; Goldman, SS; Volkow, N; Wolf, AP, 1983) |
| "In the other primary brain tumors, however, the relationship between levels of N1-AcSpd in tissue and biological malignancy should be examined in each histopathological type." | 1.29 | Relationship between tissue polyamine levels and malignancy in primary brain tumors. ( Kurihara, H; Matsuzaki, S; Tamura, M; Tsukahara, T; Yamazaki, H, 1993) |
| "Putrescine level was significantly increased in children with medulloblastomas." | 1.27 | CSF polyamines in childhood. ( Albright, AL; Lubich, WP; Marton, LJ; Reigel, DH, 1983) |
| "CSF putrescine values were closely correlated with clinical state, with the highest concentrations identified in patients with widely disseminated recurrent disease." | 1.27 | Cerebrospinal fluid polyamines: biochemical markers of malignant childhood brain tumors. ( De Vivo, DC; Kremzner, LT; Phillips, PC, 1986) |
| "In one subject with brain metastases, both [11C]PUT and GMR correlated with a declining clinical picture in repeated studies over a 4-mo period." | 1.27 | Serial PET studies of human cerebral malignancy with [1-11C]putrescine and [1-11C]2-deoxy-D-glucose. ( Brodie, JD; Christman, DR; Flamm, E; Fowler, JS; Hiesiger, E; Logan, J; MacGregor, RR; McPherson, D; Volkow, ND; Wolf, AP, 1987) |
| "Putrescine levels were elevated in all astrocytomas assayed, and the magnitude of this elevation was proportional to the malignancy of the tumor as determined by histopathological criteria." | 1.26 | Putrescine as a biochemical marker of malignant brain tumors. ( Harik, SI; Sutton, CH, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (67.86) | 18.7374 |
| 1990's | 15 (26.79) | 18.2507 |
| 2000's | 2 (3.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (1.79) | 2.80 |
| Authors | Studies |
|---|---|
| Xiong, N | 1 |
| Gao, X | 1 |
| Zhao, H | 1 |
| Cai, F | 1 |
| Zhang, FC | 1 |
| Yuan, Y | 1 |
| Liu, W | 1 |
| He, F | 1 |
| Zacharias, LG | 1 |
| Lin, H | 1 |
| Vu, HS | 1 |
| Xing, C | 1 |
| Yao, DX | 1 |
| Chen, F | 1 |
| Luo, B | 1 |
| Sun, W | 1 |
| DeBerardinis, RJ | 1 |
| Xu, H | 1 |
| Ge, WP | 1 |
| Dot, J | 1 |
| Lluch, M | 1 |
| Blanco, I | 1 |
| Rodríguez-Alvarez, J | 1 |
| Marton, LJ | 31 |
| Kersten, W | 1 |
| Hung, DT | 3 |
| Deen, DF | 10 |
| Shafer, RH | 1 |
| Alhonen-Hongisto, L | 2 |
| Oredsson, SM | 3 |
| Gray, JW | 3 |
| Pegg, AE | 1 |
| Volkow, N | 1 |
| Goldman, SS | 2 |
| Flamm, ES | 2 |
| Cravioto, H | 1 |
| Wolf, AP | 4 |
| Brodie, JD | 4 |
| Seidenfeld, J | 7 |
| Albright, AL | 1 |
| Lubich, WP | 3 |
| Reigel, DH | 1 |
| Pierangelli, E | 1 |
| Levin, VA | 5 |
| Harik, SI | 2 |
| Basu, HS | 4 |
| Pellarin, M | 3 |
| Feuerstein, BG | 5 |
| Shirahata, A | 1 |
| Samejima, K | 1 |
| Sessa, A | 1 |
| Broglia, E | 1 |
| Terreni, MR | 1 |
| Perin, A | 1 |
| Ernestus, RI | 2 |
| Röhn, G | 2 |
| Hossmann, KA | 1 |
| Paschen, W | 2 |
| Redgate, ES | 4 |
| Grudziak, A | 1 |
| Floyd, KL | 1 |
| Deutsch, M | 3 |
| Boggs, SS | 4 |
| Kurihara, H | 1 |
| Matsuzaki, S | 3 |
| Yamazaki, H | 3 |
| Tsukahara, T | 3 |
| Tamura, M | 1 |
| Schröder, R | 1 |
| Els, T | 1 |
| Lee, JY | 1 |
| Klug, N | 1 |
| Grudziak, AG | 2 |
| Watanabe, S | 1 |
| Sato, S | 1 |
| Nagase, S | 1 |
| Shimosato, K | 1 |
| Ohkuma, S | 1 |
| Alexander, D | 1 |
| Magra, TR | 1 |
| Henretty, JS | 1 |
| Patrene, KD | 1 |
| Sutton, CH | 1 |
| Devor, WN | 1 |
| Edwards, MS | 1 |
| Wilson, CB | 6 |
| Heby, O | 6 |
| Seiler, N | 1 |
| Lamberty, U | 1 |
| Al-Therib, MJ | 1 |
| Martinez, HM | 1 |
| Lee, PL | 2 |
| Crafts, DC | 1 |
| Fowler, JS | 3 |
| Volkow, ND | 3 |
| Hiesiger, E | 2 |
| Sturkenboom, MC | 1 |
| Delcros, JG | 1 |
| Csokan, PP | 1 |
| Szollosi, J | 1 |
| Hiesiger, EM | 1 |
| Logan, J | 2 |
| MacGregor, RR | 2 |
| Christman, DR | 2 |
| Rottenberg, DA | 1 |
| Bergeron, RJ | 1 |
| Nakamura, M | 1 |
| Uki, J | 2 |
| Phillips, PC | 1 |
| Kremzner, LT | 1 |
| De Vivo, DC | 1 |
| McPherson, D | 1 |
| Flamm, E | 1 |
| Brodie, J | 1 |
| Scalabrino, G | 1 |
| Ferioli, ME | 1 |
| Luccarelli, G | 1 |
| Takaue, Y | 1 |
| Nishioka, K | 1 |
| van Eys, J | 1 |
3 reviews available for putrescine and Benign Neoplasms, Brain
| Article | Year |
|---|---|
[Tumor therapy: control of results by analysis of polyamines?].
Topics: Brain Neoplasms; Enzyme Induction; Evaluation Studies as Topic; Gonadal Steroid Hormones; Humans; Le | 1983 |
Polyamines and brain tumors.
Topics: Animals; Brain Neoplasms; Humans; Polyamines; Putrescine; Spermidine | 1977 |
Polyamine biosynthesis in primary tumors of human central nervous system: review of current knowledge.
Topics: Adenosylmethionine Decarboxylase; Brain Neoplasms; Erythrocytes; Humans; Ornithine Decarboxylase; Po | 1985 |
53 other studies available for putrescine and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Using arterial-venous analysis to characterize cancer metabolic consumption in patients.
Topics: Acetylcarnitine; Adult; Aged; Agmatine; Biomarkers, Tumor; Blood; Blood Chemical Analysis; Blood Glu | 2020 |
Polyamine uptake in cultured cerebellar granule neurons.
Topics: Animals; Astrocytes; Biogenic Polyamines; Brain Neoplasms; Cell Line, Tumor; Cells, Cultured; Cerebe | 2004 |
CSF polyamines. Potential as brain tumor markers.
Topics: Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Glioblastoma; Humans; Medulloblastoma; Polyamine | 1981 |
Depletion of intracellular polyamines may alter DNA conformation in 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; DNA, Neoplasm; Eflornithine; Molecular Conformation; Ornithine; Polyamines | 1983 |
Time dependence of the potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity caused by alpha-difluoromethylornithine-induced polyamine depletion in 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Drug Synergism; Eflornithine; Kinetics; Ornithine; | 1984 |
Progressive increase in polyamine levels in 9L cells in vitro during the cell cycle: comparison between cells isolated by centrifugal elutriation and cells grown in synchrony.
Topics: Animals; Brain Neoplasms; Cell Cycle; Cell Line; Centrifugation; Kinetics; Polyamines; Putrescine; R | 1984 |
Potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity in 9L rat brain tumor cells by methylglyoxal-bis(guanylhydrazone), an inhibitor of S-adenosyl-L-methionine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Animals; Brain Neoplasms; Carboxy-Lyases; Carmustine; Cell Surviva | 1984 |
Labeled putrescine as a probe in brain tumors.
Topics: Animals; Autoradiography; Brain Neoplasms; Glioma; Kinetics; Neoplasm Transplantation; Putrescine; R | 1983 |
Depletion of intracellular polyamine content does not alter the survival of 9L rat brain tumour cells after X-irradiation.
Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Cells, Cultured; DNA; DNA, Neoplasm; Eflornithin | 1980 |
Depletion of 9L rat brain tumor cell polyamine content by treatment with D,L-alpha-difluoromethylornithine inhibits proliferation and the G1 to S transition.
Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; Dose-Response Relationship, Drug; Eflornithine; | 1981 |
Sensitization of 9L rat brain gliosarcoma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; Cell Line; Cell Survival; Dose-Response Relationsh | 1981 |
Decreased cytotoxicity of cis-diamminedichloroplatinum(II) by alpha-difluoromethylornithine depletion of polyamines in 9L rat brain tumor cells in vitro.
Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cisplatin; DNA; Eflornithine; Neoplasms, Experimental; Orn | 1982 |
CSF polyamines in childhood.
Topics: Age Factors; Brain Neoplasms; Child; Child, Preschool; Encephalocele; Humans; Hydrocephalus; Meningo | 1983 |
Putrescine diffusion in cat brain and capillary permeability in rat brain: relation to CSF putrescine levels in brain tumor patients.
Topics: Animals; Brain; Brain Neoplasms; Capillary Permeability; Cats; Diffusion; Male; Putrescine; Rats; Ur | 1981 |
Polyamines: relation to brain tumor therapy and monitoring.
Topics: Brain Neoplasms; Humans; Nervous System Diseases; Polyamines; Putrescine; Reference Values | 1981 |
Effects of DL-alpha-methylornithine on proliferation and polyamine content of 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cell Division; Cells, Cultured; Neoplasms, Experimental; O | 1980 |
CSF putrescine levels. The enzymatic-isotopic method vs liquid chromatography.
Topics: Brain Neoplasms; Chromatography, Ion Exchange; Clinical Enzyme Tests; Humans; Putrescine | 1981 |
Interaction of a polyamine analogue, 1,19-bis-(ethylamino)-5,10,15- triazanonadecane (BE-4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines.
Topics: Brain Neoplasms; Cell Division; Cell Survival; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug | 1993 |
Diamine oxidase activity in rat brain carcinogenesis and in gliomas.
Topics: Amine Oxidase (Copper-Containing); Animals; Brain Neoplasms; Ethylnitrosourea; Female; Fetus; Glioma | 1993 |
Polyamine metabolism in experimental brain tumors of rat.
Topics: Animals; Brain; Brain Neoplasms; Clone Cells; Functional Laterality; Glioma; Male; Organ Specificity | 1993 |
Effect of D,L-alpha-difluoromethylornithine (DFMO) enhanced [3H]putrescine uptake on 9L tumor cell growth and colony forming efficiency.
Topics: Animals; Biological Transport; Brain Neoplasms; Cell Division; Eflornithine; Glioma; Kinetics; Putre | 1993 |
Relationship between tissue polyamine levels and malignancy in primary brain tumors.
Topics: Adolescent; Adult; Aged; Biomarkers, Tumor; Brain; Brain Neoplasms; Child; Child, Preschool; Chromat | 1993 |
Polyamine metabolism in gliomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; F | 1996 |
Difluoromethylornithine enhanced uptake of tritiated putrescine in 9L rat brain tumors.
Topics: Animals; Brain; Brain Neoplasms; Eflornithine; Glioma; Male; Ornithine Decarboxylase Inhibitors; Put | 1997 |
Choice of vincristine or 6-mercaptopurine on the basis of polyamine level in tumor-bearing regions of the brain.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Chroma | 1999 |
Enhanced uptake of [3H] spermidine by 9L rat brain tumors after direct intratumoral infusion of inhibitors of enzymes of the polyamine biosynthetic pathway.
Topics: Adenosylmethionine Decarboxylase; Animals; Biological Transport; Body Weight; Brain Neoplasms; Corpu | 1999 |
The effect of DFMO induced uptake of [3H] putrescine on human glioma cells.
Topics: Biological Transport; Brain Neoplasms; Cell Adhesion; Cell Division; Colony-Forming Units Assay; Efl | 2001 |
Putrescine as a biochemical marker of malignant brain tumors.
Topics: Astrocytoma; Brain Chemistry; Brain Neoplasms; Glioblastoma; Humans; Neoplasms, Nerve Tissue; Putres | 1979 |
Kinetics and distribution of tritiated putrescine in the domestic cat.
Topics: Animals; Astrocytoma; Brain Neoplasms; Cats; Dose-Response Relationship, Drug; Glioblastoma; Kinetic | 1979 |
Predictive value of cerebrospinal fluid polyamines in medulloblastoma.
Topics: Adolescent; Adult; Brain Neoplasms; Child; False Negative Reactions; Female; Humans; Male; Medullobl | 1979 |
Depletion of intracellular putrescine and spermidine by alpha-difluromethylornithine does not inhibit proliferation of 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cell Division; Depression, Chemical; Dose-Response Relatio | 1979 |
Effect of methylglyoxal-bis (guanylhydrazone), an inhibitor of spermidine and spermine synthesis, on cell cycle traverse.
Topics: Animals; Brain Neoplasms; Cell Cycle; Cells, Cultured; Guanidines; Mitoguazone; Putrescine; Rats; Sp | 1977 |
Acetyl-coenzyme A: 1,4-diaminobutane N-acetyltransferase: activity in rat brain during development, in experimental brain tumours and in brains of fish of different metabolic activity.
Topics: Acetyltransferases; Aging; Animals; Brain; Brain Neoplasms; Butylamines; Cell Nucleus; Diamines; Gli | 1975 |
Polyamines: a high correlation with cell replication.
Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; Cells, Cultured; DNA, Neoplasm; Nitrosourea Comp | 1975 |
More sensitive automated detection of polyamines in physiological fluids and tissue extracts with omicron-phthalaldehyde.
Topics: Aldehydes; Amniotic Fluid; Animals; Autoanalysis; Brain Neoplasms; Evaluation Studies as Topic; Fema | 1975 |
The relationship of polyamines in cerebrospinal fluid to the presence of central nervous system tumors.
Topics: Adenoma; Astrocytoma; Brain Neoplasms; Central Nervous System Diseases; Glioma; Humans; Medulloblast | 1976 |
The value of "the putrescine experience".
Topics: Brain Neoplasms; Carbon Radioisotopes; Humans; Putrescine; Tomography, Emission-Computed | 1992 |
Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumour cells.
Topics: Brain Neoplasms; Cell Nucleus; Chromatin; Culture Media, Serum-Free; Deoxyribonuclease I; Eflornithi | 1992 |
Is [1-11C]putrescine useful as a brain tumor marker?
Topics: Biomarkers, Tumor; Brain; Brain Neoplasms; Carbon Radioisotopes; Glioma; Humans; Necrosis; Putrescin | 1992 |
Carbon-11-putrescine: back to the drawing board.
Topics: Brain; Brain Neoplasms; Carbon Radioisotopes; Humans; Putrescine; Tomography, Emission-Computed | 1992 |
Effect on N1,N14-bis-(ethyl)-homospermine (BE-4-4-4) on the growth of U-251 MG and SF-188 human brain tumor cells.
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line; Cell Survival; Humans; Kinetics; Polyamines; Putr | 1991 |
Effect of N1,N14-bis(ethyl)homospermine on the growth of U-87 MG and SF-126 human brain tumor cells.
Topics: Brain Neoplasms; Cell Division; Humans; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1990 |
[Free and acetylated polyamines in cyst fluids of brain tumors].
Topics: Brain Neoplasms; Chromatography, High Pressure Liquid; Cysts; Humans; Polyamines; Putrescine; Spermi | 1986 |
Cerebrospinal fluid polyamines: biochemical markers of malignant childhood brain tumors.
Topics: Adolescent; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Humans; Medulloblastoma; Neoplasm | 1986 |
Serial PET studies of human cerebral malignancy with [1-11C]putrescine and [1-11C]2-deoxy-D-glucose.
Topics: Adult; Aged; Astrocytoma; Blood Glucose; Brain Neoplasms; Carbon Radioisotopes; Deoxy Sugars; Deoxyg | 1987 |
Putrescine metabolism in human brain tumors.
Topics: Astrocytoma; Brain Neoplasms; Humans; In Vitro Techniques; Meningioma; Neurilemmoma; Putrescine; Spe | 1986 |
Modification of uptake and antiproliferative effect of methylglyoxal bis(guanylhydrazone) by treatment with alpha-difluoromethylornithine in rodent cell lines with different sensitivities to methylglyoxal bis(guanylhydrazone).
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Eflornithine; Guanidines; Kinetics; Mito | 1985 |
Effects of dicyclohexylamine sulfate, a spermidine synthase inhibitor, in 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; Cell Survival; Cyclohexylamines; Eflornithine; Mit | 1985 |
Elevated levels of free putrescine and N1-acetylspermidine in cyst fluids of malignant brain tumours.
Topics: Brain; Brain Neoplasms; Cysts; Humans; Putrescine; Spermidine; Spermine | 1986 |
Evaluation of polyamine levels in cerebrospinal fluid of children with brain tumors.
Topics: Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Ependymoma; Female; Humans; Infant; Male; Med | 1986 |
Increased polyamine concentrations in the cerebrospinal fluid of patients with brain tumors.
Topics: Adenoma, Acidophil; Adenoma, Chromophobe; Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Cer | 1974 |
Polyamine metabolism in tumor, spleen and liver of tumor-bearing rats.
Topics: Animals; Body Weight; Brain Neoplasms; Carbon Radioisotopes; Carboxy-Lyases; Liver; Male; Neoplasm T | 1974 |
An automated micromethod for the quantitative analysis of di- and polyamines utilizing a sensitive high pressure liquid chromatographic procedure.
Topics: Animals; Autoanalysis; Brain; Brain Chemistry; Brain Neoplasms; Cadaverine; Carbon Radioisotopes; Ch | 1974 |