putrescine has been researched along with B16 Melanoma in 11 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "As a result of bioassay-guided fractionation, betulinic acid, a pentacyclic triterpene, was identified as a melanoma-specific cytotoxic agent." | 7.69 | Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis. ( Beecher, CW; Brown, DM; Chagwedera, TE; Chai, H; Cordell, GA; Farnsworth, NR; Fong, HH; Kinghorn, AD; Lee, IS; Pisha, E, 1995) |
| "The uptake of intracellular putrescine and spermidine was examined in B16 melanoma cells." | 7.68 | Evidence for the existence of distinct transporters for the polyamines putrescine and spermidine in B16 melanoma cells. ( Ilett, KF; Martin, RL; Minchin, RF; Raso, A, 1991) |
| "Several bipyridinium, tetrapyridinium and hexapyridinium quaternary salts have been found to be potent inhibitors of putrescine uptake into B16 melanoma cells which had previously been treated with difluoromethylornithine." | 7.67 | Inhibition of putrescine uptake by polypyridinium quaternary salts in B16 melanoma cells treated with difluoromethylornithine. ( Ilett, KF; Martin, RL; Minchin, RF; Summers, LA, 1989) |
| "As a result of bioassay-guided fractionation, betulinic acid, a pentacyclic triterpene, was identified as a melanoma-specific cytotoxic agent." | 3.69 | Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis. ( Beecher, CW; Brown, DM; Chagwedera, TE; Chai, H; Cordell, GA; Farnsworth, NR; Fong, HH; Kinghorn, AD; Lee, IS; Pisha, E, 1995) |
| "The uptake of intracellular putrescine and spermidine was examined in B16 melanoma cells." | 3.68 | Evidence for the existence of distinct transporters for the polyamines putrescine and spermidine in B16 melanoma cells. ( Ilett, KF; Martin, RL; Minchin, RF; Raso, A, 1991) |
| "We have examined the effect of difluoromethylornithine on the ability of B16 melanoma cells to take up putrescine and the 4,4'-dipyridyl herbicide paraquat." | 3.67 | Paraquat is not accumulated in B16 tumor cells by the polyamine transport system. ( Ilett, KF; Martin, RL; Minchin, RF, 1989) |
| "Several bipyridinium, tetrapyridinium and hexapyridinium quaternary salts have been found to be potent inhibitors of putrescine uptake into B16 melanoma cells which had previously been treated with difluoromethylornithine." | 3.67 | Inhibition of putrescine uptake by polypyridinium quaternary salts in B16 melanoma cells treated with difluoromethylornithine. ( Ilett, KF; Martin, RL; Minchin, RF; Summers, LA, 1989) |
| "DFMO inhibited the proliferation of B16 melanoma cells in culture but the inhibitory effect was much less than that on BPAE cells." | 1.28 | Tumor angiogenesis and polyamines: alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits B16 melanoma-induced angiogenesis in ovo and the proliferation of vascular endothelial cells in vitro. ( Enomoto, M; Kinoshita, A; Nishida, Y; Pan, HO; Suzuki, F; Takigawa, M, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 2 |
| Sun, Y | 1 |
| Yan, R | 1 |
| Wu, X | 1 |
| Zou, H | 1 |
| Meng, Y | 1 |
| Yamamichi, S | 1 |
| Nishitani, M | 1 |
| Nishimura, N | 1 |
| Matsushita, Y | 1 |
| Hasumi, K | 1 |
| Wang, JF | 1 |
| Su, RB | 1 |
| Wu, N | 1 |
| Xu, B | 1 |
| Lu, XQ | 1 |
| Liu, Y | 1 |
| Baldini, PM | 1 |
| Lentini, A | 1 |
| Mattioli, P | 1 |
| Provenzano, B | 1 |
| De Vito, P | 1 |
| Vismara, D | 1 |
| Beninati, S | 2 |
| Pisha, E | 1 |
| Chai, H | 1 |
| Lee, IS | 1 |
| Chagwedera, TE | 1 |
| Farnsworth, NR | 1 |
| Cordell, GA | 1 |
| Beecher, CW | 1 |
| Fong, HH | 1 |
| Kinghorn, AD | 1 |
| Brown, DM | 1 |
| Abbruzzese, A | 1 |
| Cardinali, M | 2 |
| Takigawa, M | 1 |
| Enomoto, M | 1 |
| Nishida, Y | 1 |
| Pan, HO | 1 |
| Kinoshita, A | 1 |
| Suzuki, F | 1 |
| Minchin, RF | 3 |
| Raso, A | 1 |
| Martin, RL | 3 |
| Ilett, KF | 3 |
| Uchino, R | 1 |
| Chung, SI | 1 |
| Summers, LA | 1 |
11 other studies available for putrescine and B16 Melanoma
| Article | Year |
|---|---|
Urea transporter B downregulates polyamines levels in melanoma B16 cells via p53 activation.
Topics: Acetylcysteine; Animals; Apoptosis; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Down-Regul | 2022 |
Polyamine-promoted autoactivation of plasma hyaluronan-binding protein.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Blood Coagulation; Carmine; Cell | 2010 |
Inhibitory effect of agmatine on proliferation of tumor cells by modulation of polyamine metabolism.
Topics: Agmatine; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Humans; L-Lactate Dehydro | 2005 |
Decrease of polyamine levels and enhancement of transglutaminase activity in selective reduction of B16-F10 melanoma cell proliferation induced by atrial natriuretic peptide.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Cell Line, Tumor; Cell Proliferation; Epidermal Growth Fa | 2006 |
Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; DNA Damage; Growth Inhibitors | 1995 |
Differences in the post-translational modification of proteins by polyamines between weakly and highly metastatic B16 melanoma cells.
Topics: Animals; Melanins; Melanoma, Experimental; Mice; Neoplasm Metastasis; Neoplasm Proteins; Putrescine; | 1993 |
Tumor angiogenesis and polyamines: alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits B16 melanoma-induced angiogenesis in ovo and the proliferation of vascular endothelial cells in vitro.
Topics: Animals; Cattle; Cell Division; Chick Embryo; DNA, Neoplasm; Eflornithine; Endothelium, Vascular; Me | 1990 |
Evidence for the existence of distinct transporters for the polyamines putrescine and spermidine in B16 melanoma cells.
Topics: Affinity Labels; Biological Transport; Carrier Proteins; Eflornithine; Kinetics; Melanoma, Experimen | 1991 |
Interaction of fibrinogen with murine melanoma cells: covalent association with cell membranes and protection against recognition by lymphokine-activated killer cells.
Topics: Animals; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Humans; Killer Cells, Lymph | 1990 |
Paraquat is not accumulated in B16 tumor cells by the polyamine transport system.
Topics: Biological Transport; Dose-Response Relationship, Drug; Eflornithine; Kinetics; Melanoma, Experiment | 1989 |
Inhibition of putrescine uptake by polypyridinium quaternary salts in B16 melanoma cells treated with difluoromethylornithine.
Topics: Animals; Eflornithine; Melanoma, Experimental; Mice; Putrescine; Pyridinium Compounds; Tumor Cells, | 1989 |