putrescine has been researched along with Arterial Occlusive Diseases in 3 studies
Arterial Occlusive Diseases: Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The possible effects of the polyamine interconversion pathway on tissue polyamine levels, brain edema formation, and ischemic injury volume were studied by using a selective irreversible inhibitor, MDL 72527, of the interconversion pathway enzyme, polyamine oxidase." | 7.70 | Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle cerebral artery occlusion. ( Başkaya, MK; Dempsey, RJ; Doğan, A; Hatcher, J; Rao, AM; Rao, VL, 1999) |
| "The possible effects of the polyamine interconversion pathway on tissue polyamine levels, brain edema formation, and ischemic injury volume were studied by using a selective irreversible inhibitor, MDL 72527, of the interconversion pathway enzyme, polyamine oxidase." | 3.70 | Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle cerebral artery occlusion. ( Başkaya, MK; Dempsey, RJ; Doğan, A; Hatcher, J; Rao, AM; Rao, VL, 1999) |
| "Cerebral ischemia causes activation of ornithine decarboxylase (ODC) gene and subsequent accumulation of putrescine, which might either directly or indirectly affect the outcome of cerebral infarct." | 3.69 | Transgenic rats as models for studying the role of ornithine decarboxylase expression in permanent middle cerebral artery occlusion. ( Alhonen, LI; Gröhn, OH; Jänne, J; Järvinen, A; Kauppinen, RA; Lukkarinen, J; Sinervirta, R, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lukkarinen, J | 1 |
| Gröhn, OH | 1 |
| Sinervirta, R | 1 |
| Järvinen, A | 1 |
| Kauppinen, RA | 1 |
| Jänne, J | 1 |
| Alhonen, LI | 1 |
| Doğan, A | 2 |
| Rao, AM | 2 |
| Hatcher, J | 1 |
| Rao, VL | 1 |
| Başkaya, MK | 1 |
| Dempsey, RJ | 2 |
| Hatcher, JF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Study of the Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage[NCT01095731] | Phase 2 | 60 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for putrescine and Arterial Occlusive Diseases
| Article | Year |
|---|---|
Transgenic rats as models for studying the role of ornithine decarboxylase expression in permanent middle cerebral artery occlusion.
Topics: Animals; Animals, Genetically Modified; Arterial Occlusive Diseases; Brain Ischemia; Cell Death; Dis | 1997 |
Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle cerebral artery occlusion.
Topics: Animals; Arterial Occlusive Diseases; Blood Gas Analysis; Blood Pressure; Body Temperature; Brain; B | 1999 |
Elevated N1-acetylspermidine levels in gerbil and rat brains after CNS injury.
Topics: Animals; Arterial Occlusive Diseases; Blood-Brain Barrier; Brain; Brain Injuries; Cerebral Arteries; | 2000 |