putrescine has been researched along with Arterial Obstructive Diseases in 3 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The possible effects of the polyamine interconversion pathway on tissue polyamine levels, brain edema formation, and ischemic injury volume were studied by using a selective irreversible inhibitor, MDL 72527, of the interconversion pathway enzyme, polyamine oxidase." | 7.70 | Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle cerebral artery occlusion. ( Başkaya, MK; Dempsey, RJ; Doğan, A; Hatcher, J; Rao, AM; Rao, VL, 1999) |
| "The possible effects of the polyamine interconversion pathway on tissue polyamine levels, brain edema formation, and ischemic injury volume were studied by using a selective irreversible inhibitor, MDL 72527, of the interconversion pathway enzyme, polyamine oxidase." | 3.70 | Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle cerebral artery occlusion. ( Başkaya, MK; Dempsey, RJ; Doğan, A; Hatcher, J; Rao, AM; Rao, VL, 1999) |
| "Cerebral ischemia causes activation of ornithine decarboxylase (ODC) gene and subsequent accumulation of putrescine, which might either directly or indirectly affect the outcome of cerebral infarct." | 3.69 | Transgenic rats as models for studying the role of ornithine decarboxylase expression in permanent middle cerebral artery occlusion. ( Alhonen, LI; Gröhn, OH; Jänne, J; Järvinen, A; Kauppinen, RA; Lukkarinen, J; Sinervirta, R, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lukkarinen, J | 1 |
| Gröhn, OH | 1 |
| Sinervirta, R | 1 |
| Järvinen, A | 1 |
| Kauppinen, RA | 1 |
| Jänne, J | 1 |
| Alhonen, LI | 1 |
| Doğan, A | 2 |
| Rao, AM | 2 |
| Hatcher, J | 1 |
| Rao, VL | 1 |
| Başkaya, MK | 1 |
| Dempsey, RJ | 2 |
| Hatcher, JF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Study of the Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage[NCT01095731] | Phase 2 | 60 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for putrescine and Arterial Obstructive Diseases
| Article | Year |
|---|---|
Transgenic rats as models for studying the role of ornithine decarboxylase expression in permanent middle cerebral artery occlusion.
Topics: Animals; Animals, Genetically Modified; Arterial Occlusive Diseases; Brain Ischemia; Cell Death; Dis | 1997 |
Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle cerebral artery occlusion.
Topics: Animals; Arterial Occlusive Diseases; Blood Gas Analysis; Blood Pressure; Body Temperature; Brain; B | 1999 |
Elevated N1-acetylspermidine levels in gerbil and rat brains after CNS injury.
Topics: Animals; Arterial Occlusive Diseases; Blood-Brain Barrier; Brain; Brain Injuries; Cerebral Arteries; | 2000 |