putrescine has been researched along with American Trypanosomiasis in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chagas disease, also known as American trypanosomiasis, is a neglected tropical disease caused by the protozoa Trypanosoma cruzi, affecting nearly 7 million people only in the Americas." | 1.91 | A combined ligand and target-based virtual screening strategy to repurpose drugs as putrescine uptake inhibitors with trypanocidal activity. ( Alba Soto, CD; Alberca, LN; Carrillo, C; Fraccaroli, L; Gavernet, L; Llanos, MA; Miranda, C; Pino-Martinez, A; Ruiz, MD; Sbaraglini, ML; Talevi, A, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Llanos, MA | 2 |
| Alberca, LN | 3 |
| Ruiz, MD | 3 |
| Sbaraglini, ML | 2 |
| Miranda, C | 2 |
| Pino-Martinez, A | 2 |
| Fraccaroli, L | 2 |
| Carrillo, C | 3 |
| Alba Soto, CD | 2 |
| Gavernet, L | 3 |
| Talevi, A | 3 |
| Dietrich, RC | 1 |
| Palestro, PH | 1 |
| Seguel, V | 1 |
| Castro, L | 1 |
| Reigada, C | 1 |
| Cortes, L | 1 |
| Díaz, MV | 1 |
| Miranda, MR | 1 |
| Pereira, CA | 1 |
| Lapier, M | 1 |
| Campos-Estrada, C | 1 |
| Morello, A | 1 |
| Kemmerling, U | 1 |
| Maya, JD | 1 |
| López-Muñoz, R | 1 |
| Majumder, S | 1 |
| Kierszenbaum, F | 1 |
| Freire-de-Lima, CG | 1 |
| Nascimento, DO | 1 |
| Soares, MB | 1 |
| Bozza, PT | 1 |
| Castro-Faria-Neto, HC | 1 |
| de Mello, FG | 1 |
| DosReis, GA | 1 |
| Lopes, MF | 1 |
5 other studies available for putrescine and American Trypanosomiasis
| Article | Year |
|---|---|
A combined ligand and target-based virtual screening strategy to repurpose drugs as putrescine uptake inhibitors with trypanocidal activity.
Topics: Chagas Disease; Danazol; Humans; Ligands; Membrane Transport Proteins; Polyamines; Putrescine; Quine | 2023 |
A combined ligand and target-based virtual screening strategy to repurpose drugs as putrescine uptake inhibitors with trypanocidal activity.
Topics: Chagas Disease; Danazol; Humans; Ligands; Membrane Transport Proteins; Polyamines; Putrescine; Quine | 2023 |
A combined ligand and target-based virtual screening strategy to repurpose drugs as putrescine uptake inhibitors with trypanocidal activity.
Topics: Chagas Disease; Danazol; Humans; Ligands; Membrane Transport Proteins; Polyamines; Putrescine; Quine | 2023 |
A combined ligand and target-based virtual screening strategy to repurpose drugs as putrescine uptake inhibitors with trypanocidal activity.
Topics: Chagas Disease; Danazol; Humans; Ligands; Membrane Transport Proteins; Polyamines; Putrescine; Quine | 2023 |
Identification of cisapride as new inhibitor of putrescine uptake in Trypanosoma cruzi by combined ligand- and structure-based virtual screening.
Topics: Biological Transport; Chagas Disease; Cisapride; Drug Evaluation, Preclinical; Ligands; Membrane Tra | 2018 |
Pentamidine antagonizes the benznidazole's effect in vitro, and lacks of synergy in vivo: Implications about the polyamine transport as an anti-Trypanosoma cruzi target.
Topics: Animals; Chagas Disease; Chlorocebus aethiops; DNA, Protozoan; Dose-Response Relationship, Drug; Glu | 2016 |
N,N'-thiophene-substituted polyamine analogs inhibit mammalian host cell invasion and intracellular multiplication of Trypanosoma cruzi.
Topics: Animals; Cell Division; Chagas Disease; Heart; Host-Parasite Interactions; Kinetics; Mice; Mice, Inb | 1993 |
Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Cells, Cultured; Chagas Disease; Cysteine Prote | 2000 |