Page last updated: 2024-10-20

putrescine and Alzheimer Disease

putrescine has been researched along with Alzheimer Disease in 11 studies

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research Excerpts

ExcerptRelevanceReference
"Age and sex are risk factors of Alzheimer's disease (AD)."1.48Sex- and age-specific modulation of brain GABA levels in a mouse model of Alzheimer's disease. ( Alia, A; Hartlage-Rübsamen, M; Höfling, C; Matysik, J; Roy, U; Roβner, S; Stute, L, 2018)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's3 (27.27)29.6817
2010's3 (27.27)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Ju, YH1
Bhalla, M1
Hyeon, SJ1
Oh, JE1
Yoo, S1
Chae, U1
Kwon, J1
Koh, W1
Lim, J1
Park, YM1
Lee, J2
Cho, IJ1
Lee, H2
Ryu, H2
Lee, CJ2
Wong, W1
Amin, M1
Tang, S1
Shalamanova, L1
Taylor, RL1
Wylie, S1
Abdullah, BM1
Whitehead, KA1
Roy, U1
Stute, L1
Höfling, C1
Hartlage-Rübsamen, M1
Matysik, J1
Roβner, S1
Alia, A1
Luo, J1
Yu, CH1
Yu, H1
Borstnar, R1
Kamerlin, SC1
Gräslund, A1
Abrahams, JP1
Wärmländer, SK1
Jo, S1
Yarishkin, O1
Hwang, YJ1
Chun, YE1
Park, M1
Woo, DH1
Bae, JY1
Kim, T1
Chun, H1
Park, HJ1
Lee, DY1
Hong, J1
Kim, HY1
Oh, SJ1
Park, SJ1
Yoon, BE1
Kim, Y1
Jeong, Y1
Shim, I1
Bae, YC1
Cho, J1
Kowall, NW1
Hwang, E1
Kim, D1
Verpillot, R1
Otto, M1
Klafki, H1
Taverna, M1
Poduslo, JF2
Wengenack, TM2
Curran, GL2
Wisniewski, T1
Sigurdsson, EM1
Macura, SI1
Borowski, BJ1
Jack, CR1
Kandimalla, KK1
Holasek, SS1
Gilles, EJ1
Ramirez-Alvarado, M1
Miller, ML1
Johnson, GV1
Morrison, LD1
Kish, SJ1

Reviews

1 review available for putrescine and Alzheimer Disease

ArticleYear
Polyamine biomarkers as indicators of human disease.
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2021, Volume: 26, Issue:2

    Topics: Acrolein; Alzheimer Disease; Apoptosis; Biomarkers; Biotransformation; Cadaverine; Cell Movement; Hu

2021

Other Studies

10 other studies available for putrescine and Alzheimer Disease

ArticleYear
Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimer's disease.
    Cell metabolism, 2022, 08-02, Volume: 34, Issue:8

    Topics: Alzheimer Disease; Ammonia; Amyloid beta-Peptides; Astrocytes; Humans; Hydrogen Peroxide; Memory Dis

2022
Pathogenic putrescine.
    Science signaling, 2022, 09-13, Volume: 15, Issue:751

    Topics: Alzheimer Disease; Astrocytes; Humans; Memory Disorders; Putrescine

2022
Sex- and age-specific modulation of brain GABA levels in a mouse model of Alzheimer's disease.
    Neurobiology of aging, 2018, Volume: 62

    Topics: Aging; Alzheimer Disease; Amyloidogenic Proteins; Animals; Astrocytes; Brain; Disease Models, Animal

2018
Cellular polyamines promote amyloid-beta (Aβ) peptide fibrillation and modulate the aggregation pathways.
    ACS chemical neuroscience, 2013, Mar-20, Volume: 4, Issue:3

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Humans; Peptide Fragments; Polyamines; Putrescine

2013
GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease.
    Nature medicine, 2014, Volume: 20, Issue:8

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Astrocytes;

2014
Simultaneous analysis by capillary electrophoresis of five amyloid peptides as potential biomarkers of Alzheimer's disease.
    Journal of chromatography. A, 2008, Dec-19, Volume: 1214, Issue:1-2

    Topics: Alzheimer Disease; Amino Acid Sequence; Ammonium Hydroxide; Amyloid beta-Peptides; Biomarkers; Elect

2008
Molecular targeting of Alzheimer's amyloid plaques for contrast-enhanced magnetic resonance imaging.
    Neurobiology of disease, 2002, Volume: 11, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; B

2002
Physiological and biophysical factors that influence Alzheimer's disease amyloid plaque targeting of native and putrescine modified human amyloid beta40.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Humans; Mice; Peptide Fragments; Plaque, A

2006
Transglutaminase cross-linking of the tau protein.
    Journal of neurochemistry, 1995, Volume: 65, Issue:4

    Topics: Alzheimer Disease; Animals; Cattle; Cross-Linking Reagents; Frontal Lobe; Guinea Pigs; Humans; Immun

1995
Brain polyamine levels are altered in Alzheimer's disease.
    Neuroscience letters, 1995, Sep-01, Volume: 197, Issue:1

    Topics: Aged; Alzheimer Disease; Biogenic Polyamines; Brain Chemistry; Calcium; Female; Humans; Male; Neurof

1995