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putrescine and Adenocarcinoma

putrescine has been researched along with Adenocarcinoma in 38 studies

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"To evaluate [1-11C]putrescine ([11C]PUT) as a potential tracer for imaging and characterization of human prostatic adenocarcinoma, positron emission tomography (PET) was performed in eight patients and three normal controls."7.69Positron emission tomography study of human prostatic adenocarcinoma using carbon-11 putrescine. ( Fowler, JS; MacGregor, RR; Madajewicz, S; Schlyer, DJ; Volkow, ND; Wang, GJ; Wolf, AP, 1994)
"Because alpha-difluoromethylornithine (DFMO) reduces the incidence of experimental colon cancers, inhibits the growth of human lung cancer cells and human leukemia cells in culture, and in combination with methylglyoxal (bis)guanylhydrazone induces remission in children with leukemia, its effectiveness against a human colon adenocarcinoma cell line (Colo 205) was tested alone and in combination with 5-fluorouracil (5-FU)."7.66Effects of alpha-difluoromethylornithine and 5-fluorouracil on the proliferation of a human colon adenocarcinoma cell line. ( Diekema, KA; Kingsnorth, AN; Malt, RA; McCann, PP; Russell, WE, 1983)
"Histamine was detected in 3 of the 6 cases of thyroid carcinomas, and in case of adenomatous goiter."5.26Elevated levels of polyamines and histamine in adenocarcinomas of the thyroid. ( Hamana, K; Itoh, K; Matsuzaki, S; Suzuki, M, 1978)
" The present results show that multidrug-resistant human colon adenocarcinoma cells (LoVo) are significantly more sensitive than corresponding wild-type cells to hydrogen peroxide and aldehydes, the products of bovine serum amine oxidase (BSAO)-catalyzed oxidation of spermine."3.73Sensitization of human colon adenocarcinoma cells (LoVo) to reactive oxygen species by a lysosomotropic compound. ( Agostinelli, E; Arancia, G; Belli, F; Condello, M; Seiler, N; Vedova, LD, 2006)
"We evaluated polyamine (putrescine, spermidine, and spermine) levels, estrogen receptor concentrations, and their relationship in neoplastic tissue and surrounding mucosa from 30 patients with gastric adenocarcinoma."3.69Estrogen receptors and polyamine levels in human gastric carcinoma. ( Cavallini, A; Di Leo, A; Linsalata, M; Messa, C; Russo, F, 1994)
"To evaluate [1-11C]putrescine ([11C]PUT) as a potential tracer for imaging and characterization of human prostatic adenocarcinoma, positron emission tomography (PET) was performed in eight patients and three normal controls."3.69Positron emission tomography study of human prostatic adenocarcinoma using carbon-11 putrescine. ( Fowler, JS; MacGregor, RR; Madajewicz, S; Schlyer, DJ; Volkow, ND; Wang, GJ; Wolf, AP, 1994)
"We assayed the estrogen receptors and polyamine levels (putrescine, spermidine and spermine) in the neoplastic and "normal" surrounding tissue of patients with colorectal cancer."3.68Polyamines and estrogen-receptor concentrations in human colorectal carcinomas. ( Cavallini, A; Di Leo, A; Guerra, V; Lacatena, M; Lantone, G; Linsalata, M; Messa, C; Notarnicola, M; Russo, F, 1992)
" Tissue concentrations of polyamines can be detected by cation exchange analysis and putrescine, spermine and spermidine were assayed in specimens of benign hyperplasia of prostate and renal adenocarcinoma and in normal control tissues."3.66Determination of putrescine, spermine and spermidine in human tissues of prostate and kidney. ( Dunzendorfer, U; Russell, DH, 1980)
"Because alpha-difluoromethylornithine (DFMO) reduces the incidence of experimental colon cancers, inhibits the growth of human lung cancer cells and human leukemia cells in culture, and in combination with methylglyoxal (bis)guanylhydrazone induces remission in children with leukemia, its effectiveness against a human colon adenocarcinoma cell line (Colo 205) was tested alone and in combination with 5-fluorouracil (5-FU)."3.66Effects of alpha-difluoromethylornithine and 5-fluorouracil on the proliferation of a human colon adenocarcinoma cell line. ( Diekema, KA; Kingsnorth, AN; Malt, RA; McCann, PP; Russell, WE, 1983)
"The aspirin effects were apparently unrelated to prostaglandin biosynthesis inhibition, since although these cells were found to express high levels of cyclooxygenase 1 (COX-1) and low levels of COX-2 proteins, they did not produce any measurable net amounts of prostaglandins, based on both utilization of radiolabelled arachidonic acid and the radioimmunoassay of prostaglandins E2 and F2 alpha."1.32Prostaglandin-independent effects of aspirin on cell cycle and putrescine synthesis in human colon carcinoma cells. ( Andriamihaja, M; Blachier, F; Camous, S; Charpigny, G; Eklou-Kalonji, E; Mayeur, C; Reinaud, P; Robert, V, 2003)
"Putrescine was taken up by HT-29 cells, leading to the production of a modest amount of spermidine."1.29Metabolism of L-arginine through polyamine and nitric oxide synthase pathways in proliferative or differentiated human colon carcinoma cells. ( Blachier, F; Duée, PH; M'Rabet-Touil, H; Robert, V; Selamnia, M, 1995)
"The investigated tumoral tissue (six squamous carcinomas and five adenocarcinomas) did not show accumulation of putrescine above that attributable to simple diffusion, except for one adenocarcinoma."1.29Putrescine accumulation in human pulmonary tumours. ( Demedts, M; Dinsdale, D; Hoet, PH; Nemery, B; Verbeken, EK, 1996)
"Putrescine is a potential scanning agent for metastases of prostatic carcinoma."1.27alpha-Difluoromethylornithine enhancement of 14C-putrescine uptake by an androgen-dependent prostatic tumor. ( Heston, WD; Kadmon, D, 1986)
"Histamine was detected in 3 of the 6 cases of thyroid carcinomas, and in case of adenomatous goiter."1.26Elevated levels of polyamines and histamine in adenocarcinomas of the thyroid. ( Hamana, K; Itoh, K; Matsuzaki, S; Suzuki, M, 1978)
"All 6 patients with localized malignant tumors had elevated urinary polyamine levels."1.25Urinary polyamine levels in human cancer. ( Kessler, GF; Lipton, A; Sheehan, LM, 1975)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199013 (34.21)18.7374
1990's19 (50.00)18.2507
2000's5 (13.16)29.6817
2010's1 (2.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morada, M1
Pendyala, L1
Wu, G1
Merali, S1
Yarlett, N1
Basu, HS1
Thompson, TA1
Church, DR1
Clower, CC1
Mehraein-Ghomi, F1
Amlong, CA1
Martin, CT1
Woster, PM1
Lindstrom, MJ1
Wilding, G1
Weiss, TS1
Bernhardt, G1
Buschauer, A1
Thasler, WE1
Dolgner, D1
Zirngibl, H1
Jauch, KW1
Eklou-Kalonji, E1
Andriamihaja, M1
Reinaud, P1
Mayeur, C1
Camous, S1
Robert, V2
Charpigny, G1
Blachier, F2
Agostinelli, E1
Vedova, LD1
Belli, F1
Condello, M1
Arancia, G1
Seiler, N2
Moulinoux, JP5
Quemener, V4
Larzul, JJ1
Le Calve, M1
Roch, AM2
Toujas, L1
Quash, G2
Thomas, V1
Delcros, JG1
Dunzendorfer, U2
Russell, DH1
Kingsnorth, AN2
Russell, WE1
McCann, PP1
Diekema, KA1
Malt, RA1
Anehus, S1
Bengtsson, G1
Andersson, G1
Carlsson, G1
Hafström, L1
Yngner, T1
Heby, O1
Smith, RC1
Litwin, MS1
Lu, Y1
Zetter, BR1
Jasnis, MA1
Klein, S1
Monte, M1
Davel, L1
Sacerdote de Lustig, E1
Algranati, ID1
Selamnia, M1
M'Rabet-Touil, H1
Duée, PH1
Milovic, V1
Deubner, C1
Zeuzem, S1
Piiper, A1
Caspary, WF1
Stein, J1
Brachet, P1
Havouis, R3
Tomé, D1
Linsalata, M3
Messa, C2
Russo, F3
Cavallini, A3
Di Leo, A3
Berloco, P1
Gray, MR1
Wallace, HM2
Goulding, H1
Hoffman, J1
Kenyon, WE1
Hoet, PH1
Dinsdale, D1
Verbeken, EK1
Demedts, M1
Nemery, B1
Cipolla, B2
Blanchard, Y1
Chamaillard, L1
Guillé, F2
Lokshin, A1
Levitt, ML1
Wang, GJ1
Volkow, ND1
Wolf, AP1
Madajewicz, S1
Fowler, JS1
Schlyer, DJ1
MacGregor, RR1
Olaya, J1
Neopikhanov, V1
Uribe, A1
Schleiffer, R1
Duranton, B1
Gossé, F1
Hasselmann, M1
Raul, F1
Lipton, A2
Sheehan, LM1
Kessler, GF2
Matsuzaki, S1
Suzuki, M1
Hamana, K1
Itoh, K1
Nishioka, K1
Romsdahl, MM1
Sanford, EJ1
Drago, JR1
Rohner, TJ1
Sheehan, L1
Twentyman, PR1
Wright, KA1
Notarnicola, M1
Guerra, V1
Lantone, G1
Lacatena, M1
Martin, C1
Lobel, B1
Tatsuta, M1
Iishi, H1
Baba, M1
Ichii, M1
Nakaizumi, A1
Uehara, H1
Taniguchi, H1
Halline, AG1
Dudeja, PK1
Jacoby, RF1
Llor, X1
Teng, BB1
Chowdhury, LN1
Davidson, NO1
Brasitus, TA1
Bowlin, TL1
Rosenberger, A1
Stemerick, D1
Edwards, ML1
Knöner, M1
Hawrylewicz, EJ1
Moshovitis, CK1
Reger, C1
Madell, J1
Heston, WD1
Kadmon, D1
Holinka, CF1
Gurpide, E1

Other Studies

38 other studies available for putrescine and Adenocarcinoma

ArticleYear
Cryptosporidium parvum induces an endoplasmic stress response in the intestinal adenocarcinoma HCT-8 cell line.
    The Journal of biological chemistry, 2013, Oct-18, Volume: 288, Issue:42

    Topics: Acetyltransferases; Adenocarcinoma; Apoptosis; Calreticulin; Cell Line, Tumor; Cryptosporidiosis; Cr

2013
A small molecule polyamine oxidase inhibitor blocks androgen-induced oxidative stress and delays prostate cancer progression in the transgenic adenocarcinoma of the mouse prostate model.
    Cancer research, 2009, Oct-01, Volume: 69, Issue:19

    Topics: Acetyltransferases; Adenocarcinoma; Androgens; Animals; Cell Line, Tumor; Disease Models, Animal; Di

2009
Polyamine levels of human colorectal adenocarcinomas are correlated with tumor stage and grade.
    International journal of colorectal disease, 2002, Volume: 17, Issue:6

    Topics: Acetyltransferases; Adenocarcinoma; Aged; Biomarkers, Tumor; Chromatography, Liquid; Colorectal Neop

2002
Prostaglandin-independent effects of aspirin on cell cycle and putrescine synthesis in human colon carcinoma cells.
    Canadian journal of physiology and pharmacology, 2003, Volume: 81, Issue:5

    Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Caco-2 Ce

2003
Sensitization of human colon adenocarcinoma cells (LoVo) to reactive oxygen species by a lysosomotropic compound.
    International journal of oncology, 2006, Volume: 29, Issue:4

    Topics: Adenocarcinoma; Aldehydes; Amine Oxidase (Copper-Containing); Animals; Antineoplastic Combined Chemo

2006
Red blood cell polyamines in mice bearing the Lewis lung carcinoma (3LL) and in patients with bronchopulmonary cancers.
    International journal of cancer, 1984, Aug-15, Volume: 34, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Animals; Bronchial Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamou

1984
A quantitative and qualitative study of the transglutaminase-mediated insertion of polyamines into plasma proteins from patients with bronchopulmonary cancer.
    International journal of cancer, 1984, Jun-15, Volume: 33, Issue:6

    Topics: Acyltransferases; Adenocarcinoma; Adult; Aged; Blood Proteins; Bronchial Diseases; Bronchial Neoplas

1984
Determination of putrescine, spermine and spermidine in human tissues of prostate and kidney.
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:10

    Topics: Adenocarcinoma; Adult; Humans; Kidney; Kidney Neoplasms; Male; Polyamines; Prostate; Prostatic Hyper

1980
Effects of alpha-difluoromethylornithine and 5-fluorouracil on the proliferation of a human colon adenocarcinoma cell line.
    Cancer research, 1983, Volume: 43, Issue:9

    Topics: Adenocarcinoma; Antineoplastic Agents; Cell Cycle; Cell Line; Cell Survival; Eflornithine; Fluoroura

1983
Urinary putrescine and plasma lactate dehydrogenase as markers of experimental adenocarcinoma growth.
    European journal of cancer, 1981, Volume: 17, Issue:5

    Topics: Adenocarcinoma; Animals; Creatinine; L-Lactate Dehydrogenase; Male; Neoplasms, Experimental; Putresc

1981
Identification of an endogenous inhibitor of prostatic carcinoma cell growth.
    Nature medicine, 1995, Volume: 1, Issue:10

    Topics: Adenocarcinoma; Animals; Enzyme Inhibitors; Growth Inhibitors; Guanidines; Humans; Male; Neoplasm In

1995
Polyamines prevent DFMO-mediated inhibition of angiogenesis.
    Cancer letters, 1994, Apr-29, Volume: 79, Issue:1

    Topics: Adenocarcinoma; Analysis of Variance; Animals; Eflornithine; Female; Lymphocytes; Mammary Neoplasms,

1994
Metabolism of L-arginine through polyamine and nitric oxide synthase pathways in proliferative or differentiated human colon carcinoma cells.
    Biochimica et biophysica acta, 1995, Sep-21, Volume: 1268, Issue:3

    Topics: Adenocarcinoma; Arginine; Cell Differentiation; Cell Division; Colonic Neoplasms; Dipeptidyl Peptida

1995
EGF stimulates polyamine uptake in Caco-2 cells.
    Biochemical and biophysical research communications, 1995, Jan-26, Volume: 206, Issue:3

    Topics: Adenocarcinoma; Biological Transport; Cell Differentiation; Colonic Neoplasms; Cycloheximide; Epider

1995
Alterations in intestinal uptake of putrescine and tissue polyamine concentrations in tumor-bearing rats.
    Biochimica et biophysica acta, 1994, Nov-29, Volume: 1227, Issue:3

    Topics: Adenocarcinoma; Animals; Body Weight; Dose-Response Relationship, Drug; Eating; Female; Intestinal A

1994
Estrogen receptors and polyamine levels in human gastric carcinoma.
    Scandinavian journal of gastroenterology, 1994, Volume: 29, Issue:1

    Topics: Adenocarcinoma; Biogenic Polyamines; Female; Gastric Mucosa; Humans; Male; Middle Aged; Putrescine;

1994
Polyamines, diamine oxidase, and ornithine decarboxylase activity in colorectal cancer and in normal surrounding mucosa.
    Diseases of the colon and rectum, 1993, Volume: 36, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amine Oxidase (Copper-Containing); Biomarkers, Tumor

1993
Mucosal polyamine metabolism in the columnar lined oesophagus.
    Gut, 1993, Volume: 34, Issue:5

    Topics: Adenocarcinoma; Barrett Esophagus; Biomarkers; Chromatography, High Pressure Liquid; Esophageal Neop

1993
Putrescine accumulation in human pulmonary tumours.
    British journal of cancer, 1996, Volume: 73, Issue:1

    Topics: Adenocarcinoma; Aged; Autoradiography; Carbon Radioisotopes; Carcinoma, Squamous Cell; Female; Human

1996
In vivo, synergestic inhibition of MAT-LyLu rat prostatic adenocarcinoma growth by polyamine deprivation and low-dose cyclophosphamide.
    Urological research, 1996, Volume: 24, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Co

1996
Effect of suramin on squamous differentiation and apoptosis in three human non-small-cell lung cancer cell lines.
    Journal of cellular biochemistry. Supplement, 1996, Volume: 24

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Calcimycin; Carcinoma, Adenosquamous; Carcinoma, S

1996
Positron emission tomography study of human prostatic adenocarcinoma using carbon-11 putrescine.
    Nuclear medicine and biology, 1994, Volume: 21, Issue:1

    Topics: Adenocarcinoma; Aged; Bone Neoplasms; Carbon Radioisotopes; Humans; Male; Middle Aged; Prostatic Neo

1994
Lipopolysaccharide of Escherichia coli, polyamines, and acetic acid stimulate cell proliferation in intestinal epithelial cells.
    In vitro cellular & developmental biology. Animal, 1999, Volume: 35, Issue:1

    Topics: Acetaldehyde; Acetic Acid; Adenocarcinoma; Ammonium Chloride; Animals; Cadaverine; Cell Division; Ce

1999
Blood polyamine levels after oral ornithine load, a diagnostic marker of hyperproliferative premalignant and malignant stages in a model of colon carcinogenesis.
    Cancer detection and prevention, 2000, Volume: 24, Issue:6

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Biotransformation; Body

2000
Urinary polyamine levels in human cancer.
    Cancer, 1975, Volume: 35, Issue:2

    Topics: Adenocarcinoma; Adenoma; Bone Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous

1975
Elevated levels of polyamines and histamine in adenocarcinomas of the thyroid.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adenoma; Adult; DNA; Female; Graves Disease; Histamine; Humans; Middle Aged; Polyami

1978
Preliminary longitudinal studies of serum polyamines in patients with colorectal carcinoma.
    Cancer letters, 1977, Volume: 3, Issue:3-4

    Topics: Adenocarcinoma; Colonic Neoplasms; Humans; Intestinal Polyps; Longitudinal Studies; Middle Aged; Pro

1977
Preliminary evaluation of urinary polyamines in the diagnosis of genitourinary tract malignancy.
    The Journal of urology, 1975, Volume: 113, Issue:2

    Topics: Adenocarcinoma; Carcinoma, Transitional Cell; Female; Humans; Kidney Neoplasms; Male; Polyamines; Pr

1975
Effects of cyclosporin A and a non-immunosuppressive analogue, O-acetyl cyclosporin A, upon the growth of parent and multidrug resistant human lung cancer cells in vitro.
    British journal of cancer, 1992, Volume: 65, Issue:3

    Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; Cell Line; Cel

1992
Polyamines and estrogen-receptor concentrations in human colorectal carcinomas.
    The Italian journal of gastroenterology, 1992, Volume: 24, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Carcinoembryonic Antigen; Colorectal Neoplasms; Female; Humans; Intesti

1992
The growth of MAT-LyLu rat prostatic adenocarcinoma can be prevented in vivo by polyamine deprivation.
    The Journal of urology, 1991, Volume: 146, Issue:5

    Topics: Adenocarcinoma; Animals; Diet; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Eflorn

1991
Inhibition by putrescine of experimental carcinogenesis in rat colon induced by azoxymethane.
    International journal of cancer, 1991, Mar-12, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Body Weight; Carcinoma in Situ; Cell Transformation,

1991
Effect of polyamine oxidase inhibition on the colonic malignant transformation process induced by 1,2-dimethylhydrazine.
    Carcinogenesis, 1990, Volume: 11, Issue:12

    Topics: 1,2-Dimethylhydrazine; Acetyltransferases; Adenocarcinoma; Animals; Base Sequence; Carcinogens; Colo

1990
Potentiation of natural killer cell activity and tumor immunity by diacetylputrescine.
    Cancer research, 1990, Sep-01, Volume: 50, Issue:17

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Colonic Neoplasms; Cytotoxicity, Immunolo

1990
[Therapy with inhibitors of polyamine biosynthesis in refractory prostatic carcinoma. An experimental and clinical study].
    Onkologie, 1985, Volume: 8, Issue:4

    Topics: Adenocarcinoma; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Carboxy-Lyases; Ca

1985
Dietary protein enhanced mammary ornithine decarboxylase activity and tumorigenesis in rats.
    The Journal of nutrition, 1989, Volume: 119, Issue:4

    Topics: Adenocarcinoma; Animals; Dietary Proteins; Epithelium; Female; Liver; Mammary Glands, Animal; Mammar

1989
alpha-Difluoromethylornithine enhancement of 14C-putrescine uptake by an androgen-dependent prostatic tumor.
    The Journal of urology, 1986, Volume: 136, Issue:4

    Topics: Adenocarcinoma; Androgens; Animals; Carbon Radioisotopes; Dexamethasone; Dihydrotestosterone; Eflorn

1986
Ornithine decarboxylase activity in human endometrium and endometrial cancer cells.
    In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1985, Volume: 21, Issue:12

    Topics: Adenocarcinoma; Cell Division; Cell Line; Corpus Luteum; Cycloheximide; Dactinomycin; Eflornithine;

1985