puromycin aminonucleoside has been researched along with Disease Models, Animal in 122 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 22 (18.03) | 18.7374 |
1990's | 31 (25.41) | 18.2507 |
2000's | 36 (29.51) | 29.6817 |
2010's | 28 (22.95) | 24.3611 |
2020's | 5 (4.10) | 2.80 |
Authors | Studies |
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Hatakeyama, S; Ishimitsu, T; Satonaka, H; Senda, T; Tojo, A; Yamada, NO | 1 |
Lin, Q; Long, C; Mo, J; Xiao, Y; Xie, Y | 1 |
Hasegawa, F; Karasawa, K; Moriyama, T; Nitta, K; Uchida, K | 1 |
Bollinger, C; Fitch, RM; Hayes, K; Warner, E; Wright, D | 1 |
Abdeen, A; Fujimoto, N; Ikeda, M; Kaito, A; Oshikawa-Hori, S; Sonoda, H | 1 |
Huo, J; Luo, Y; Qiu, X; Xia, S; Xia, Y; Zhao, W | 1 |
Demirkiran, ÖD; Güngör, ZB; Köktürk, S; Pekpak, M; Saygi, Hİ; Seçkin, İ; Sönmez, HA; Uzunalan, M; Yaprak Saraç, E | 1 |
Akagawa, Y; Kaneko, K; Kimata, T; Kino, J; Kitao, T; Tsuji, S; Yamanouchi, S | 1 |
Asanuma, K; Hidaka, T; Ishidoh, K; Kubo, A; Sasaki, Y; Shirato, I; Suzuki, Y; Takagi, M | 1 |
Abe, M; Kawasaki, Y; Natori, Y; Sugiyama, A; Yonezawa, S | 1 |
Ichimura, K; Kakuta, S; Kawasaki, Y; Kinoshita, M; Miyaki, T; Sakai, T | 1 |
Chen, X; Ding, G; Gong, W; Huang, S; Jia, Z; Li, S; Song, J; Xia, W; Yu, J; Zhang, A; Zhang, Y | 1 |
Kidder, K; Li, L; Li, S; Liang, H; Liu, Y; Liu, Z; Rong, W; Yang, R; Zen, K; Zeng, C; Zhang, M; Zhu, X | 1 |
Chen, Z; Fan, Y; Liu, Z; Qin, W; Wang, X; Wu, J; Zen, K; Zeng, C; Zhang, C; Zhang, M; Zhang, W; Zheng, C; Zhu, X | 1 |
Chen, Z; Fan, Y; Liu, Z; Shi, S; Wu, J; Zen, K; Zeng, C; Zhang, C; Zhong, Y | 1 |
Comper, WD; Greive, K; Koltun, M; Vuchkova, J | 1 |
Eguchi, A; Farquhar, MG; Ghosh, P; Misaki, T; Taupin, V; Wang, H | 1 |
Fukusumi, Y; Kawachi, H; Kayaba, M; Kitazawa, Y; Takahashi, A; Tomita, M; Yamazaki, M | 1 |
Fujitaka, K; Fukunari, A; Kakimoto, T; Kato, T; Nishio, M; Okada, K; Utsumi, H | 1 |
Chanley, MA; Kerlin, BA; Nieman, MT; Sharma, R; Smoyer, WE; Waller, AP | 1 |
Bailey, S; Brown, T; Carraher, D; Homer, BL; Li, Y; Li, Z; Mathur, S; Nassirpour, R; O'Neil, SP; Percival, K; Warneke, J; Whiteley, LO | 1 |
Ding, F; Ding, J; Li, B; Li, X; Zhang, X | 1 |
Ding, F; Ding, J; Ju, W; Li, S; Li, X; Tan, A | 1 |
Ben-Dor, L; Chagnac, A; Evron, Y; Herman-Edelstein, M; Hirsch, Y; Nevo, Z; Schwartz, D; Schwartz, I; Skutelsky, E; Weinstein, T | 1 |
Karasawa, K; Moriyama, T; Nitta, K; Sasaki, K; Uchida, K | 1 |
Kaneko, K; Kaneshiro, Y; Matsuo, T; Nakajima, K; Ohno, Y; Tanaka, H; Yamashita, J | 1 |
Fujita, K; Fujita, T; Kamata, Y; Kumagai, Y; Majima, M; Ohtani, Y; Yasuda, S | 1 |
Aoudjit, L; Blasutig, IM; Eremina, V; Fortino, MA; Jones, N; Liu, X; New, LA; Pawson, T; Quaggin, SE; Ruston, J; Takano, T; Yu, GL; Zou, Y | 1 |
Fujimoto, S; Fukuda, A; Iwatsubo, S; Kawachi, H; Kitamura, K | 1 |
Funk, J; Herrmann, A; Tozzo, E | 1 |
Ebefors, K; Granqvist, A; Haraldsson, B; Nilsson, UA; Nyström, J | 1 |
Fujinaka, H; Katsuyama, K; Nameta, M; Tomizawa, S; Yamamoto, K; Yamamoto, T; Yaoita, E; Yoshida, Y | 1 |
Fogo, AB; Ichikawa, I; Kon, V; Ma, J; Matsusaka, T; Takagi, N; Yang, HC; Zhong, J | 1 |
Agrawal, S; Benndorf, R; Guess, AJ; Manley, J; Mourey, RJ; Pengal, R; Ransom, RF; Smoyer, WE | 1 |
Chen, J; Fu, W; Lei, Y; Ruan, J; Wu, G; Xiong, C; Zhang, Y | 1 |
Demirci, S; Kokturk, S; Oztürk, Z; Pekpak, M; Seckin, I; Sonmez, H; Uzunalan, M; Yaprak, E | 1 |
Baliga, M; Baliga, R; Bigler, SA; Liu, H | 1 |
Alique, M; Arribas, I; Chen, S; Iglesias-de la Cruz, MC; Kitamura, M; Lucio Cazana, FJ; Mampaso, F; Moreno-Manzano, V; Nieto, E; Orellana, JM; Reyes, P; Rodríguez, J; Sepúlveda-Muñoz, JC; Xu, Q; Ziyadeh, FN | 1 |
Durvasula, RV; Shankland, SJ | 1 |
Cooper, ME; Cox, AJ; Gilbert, RE; Kanellis, J; Khong, T; Levidiotis, V; Power, DA; Stacker, SA | 1 |
Ito, S; Kimura, T; Nakayama, K; Natori, Y; Saito, T; Sato, H; Sato, T; Sugiura, A | 1 |
Baylis, C; Engels, K; Erdely, A; Freshour, G; Olson, JL; Smith, C | 1 |
Deng, J; Ding, J; Guan, N; Yang, J; Zhang, J | 1 |
Huh, W; Kawachi, H; Kim, DJ; Kim, YG; Kwon, T; Lee, YK; Oh, HY | 1 |
Eto, T; Fujimoto, S; Fukae, H; Kikuchi, M; Kinoshita, H; Kita, T; Nakazato, M | 1 |
Bistrup, C; Jensen, BL; Skøtt, O; Thiesson, HC | 1 |
Kawachi, H; Koshikawa, M; Mori, K; Mukoyama, M; Nagae, T; Nakao, K; Sawai, K; Shimizu, F; Suganami, T; Sugawara, A; Yokoi, H; Yoshioka, T | 1 |
Mosquera, JA; Pedreáñez, A; Rincón, JC; Romero, MJ; Viera, NT | 1 |
Haraldsson, B; Hjalmarsson, C; Lidell, ME | 1 |
Li, H; Nameta, M; Qu, Z; Watanabe, Y; Yamamoto, T; Yaoita, E; Yoshida, Y; Zou, J | 1 |
Fujita, T; Nagase, M; Shibata, S | 1 |
Datta, PK; Lianos, EA; Reddy, S; Sharma, M | 1 |
Henriques-Coelho, T; Leite-Moreira, A; Moreira-Rodrigues, M; Pestana, M; Roncon-Albuquerque, R; Sampaio-Maia, B | 1 |
Eto, N; Fujita, T; Inagi, R; Kato, H; Kawachi, H; Kurihara, H; Nangaku, M; Shankland, SJ; Shimizu, A; Takano, H; Wada, T | 1 |
Brinkkoetter, PT; Krofft, RD; Logar, CM; Pippin, JW; Shankland, SJ | 1 |
Aoyama, M; Hirayama, A; Inoue, M; Nagase, S; Oteki, T; Ueda, A; Yokoyama, H | 1 |
Cardoso, LR; Guimarães, MA; Mourão, PA; Pomin, VH; Santos, AM; Stelling, MP | 1 |
Castañeda-Hernández, G; Medeiros, M; Muñoz-Arizpe, R; Pedraza-Chaverri, J; Pérez-Urizar, J | 1 |
Ellis, MJ; Fields, TA; Howell, DN; Spurney, RF; Wang, L | 1 |
Biswas, N; Flory, W; Hollerman, CE; Neuhaus, OW | 1 |
Arakawa, M; Furuyama, T; Kyogoku, Y; Saito, T; Yamakage, K; Yoshinaga, K | 1 |
Cotran, RS; Schreiner, GF; Unanue, ER | 1 |
Fujiwara, Y | 1 |
Bartosek, I; Calandra, S; Fainaru, M; Gherardi, E; Guaitani, A | 1 |
Ailenberg, M; Downey, GP; Silverman, M; Waddell, TK; Zent, R | 1 |
Chen, A; Ding, SL; Lee, WH; Sheu, LF; Wei, CH | 1 |
Fawcett, JP; Jiang, R; Walker, RJ | 1 |
Sturman, JA; Trachtman, H | 1 |
Furness, PN; Harris, K | 1 |
Abe, H; Guoji, Y; Orita, M; Tashiro, K | 1 |
Ebihara, I; Fukui, M; Koide, H; Nakamura, T; Suzuki, S; Tomino, Y; Yaguchi, Y | 1 |
Andrews, PM; Petroll, WM; Pulver, M | 1 |
Cruz, C; Ibarra-Rubio, ME; Medina-Campos, ON; Pedraza-Chaverrí, J; Sosa, G | 1 |
Baliga, R; Shah, SV; Ueda, N | 1 |
Chan, JC; Chan, W; Futterweit, S; Ma, C; Maesaka, J; Trachtman, H; Valderrama, E | 1 |
Magil, A | 1 |
Qi, M; Tang, WW; Van, GY | 1 |
al-Shurbaji, A; Berge, RK; Berglund, L; Cederblad, G; Humble, E | 1 |
Evans, GO; Goodwin, DA; Hawksworth, GM; Hodgson, ST; Morley, TJ; Read, NG | 1 |
Brandes, RP; Eberhard, O; Gwinner, W; Koch, KM; Kubat, B; Landmesser, U; Olbricht, CJ; Plasger, J | 1 |
Liang, K; Vaziri, ND | 1 |
Hanada, S; Maruyama, T; Matsui, T; Nakamura, N; Shintome, M; Tsuchiyama, H; Tsukada, M; Yuki, T | 1 |
Cambar, J; Combe, C; Delalande, C; Deminiere, C; Grenier, N; Hauger, O; Kahn, H; Quesson, B; Trillaud, H | 1 |
Fraser, S; Kanellis, J; Katerelos, M; Khong, T; Kirkland, G; Paizis, K; Power, DA | 1 |
Natori, Y; Ou, ZL | 1 |
Kojima, K; Matsui, K; Nagase, M | 1 |
Aaltonen, P; Ahola, H; Holthöfer, H; Kerjaschki, D; Luimula, P; Solin, ML; Tikkanen, I; Wang, SX | 1 |
Granados-Silvestre, MA; Hernández-Pando, R; Maldonado, PD; Medina-Campos, ON; Olivares-Corichi, IM; Pedraza-Chaverrí, J | 1 |
Ascencio, C; Medina-Campos, ON; Pedraza-Chaverri, J; Torres, N; Tovar, AR | 1 |
Bhaskaran, M; Ding, G; Franki, N; Kapasi, A; Pandya, M; Reddy, K; Sanwal, V; Singhal, PC; Valderrama, E | 1 |
Aw, TC; Saw, S; Sinniah, R | 1 |
Chang, JM; Chen, HC; Guh, JY; Hwang, SJ; Lai, YH; Tsai, JC | 1 |
Amano, O; Fan, L; Iseki, S; Wakayama, T; Yokoyama, S | 1 |
Goyal, M; Kershaw, D; Kim, YH; Wharram, B; Wiggins, J; Wiggins, R | 1 |
Holthöfer, H; Luimula, P; Novikov, D; Sandström, N | 1 |
Belok, S; Couser, WG; Hoyer, JR; Jermanovich, NB; Stilmant, MM | 1 |
Chen, CY; de Mendoza, SG; Kashyap, ML; Lutmer, RF | 1 |
Hein, SJ; Karnovsky, MJ; Ryan, GB | 1 |
Glasser, RJ; Michael, AF; Velosa, JA | 1 |
Glasser, RJ; Michael, AF; Nevins, TE; Velosa, JA | 1 |
Elema, JD; Hoyer, JR; Vernier, RL | 1 |
Hoyer, JR; Mauer, SM; Michael, AF | 1 |
Amherdt, M; Humbert, F; Orci, L; Perrelet, A; Pricam, C | 1 |
Buch, S; Eddy, AA; Jones, CL; Liu, E; McCulloch, L; Post, M | 2 |
Morgan, K; Morgan, TR; Pandian, MR; Vaziri, ND | 1 |
Alvarado, JA; Amato, D; Bobadilla, NA; Calleja, C; Franco, M; García-Torres, R; Herrera-Acosta, J; López, P; Tapia, E | 1 |
Chiba, S; Obara, K; Saito, T; Sato, H; Shoji, Y; Soma, J; Yoshinaga, K | 1 |
Carlson, EC; Rada, JA | 1 |
Horie, M; Mase, T; Nagaoka, H; Sakurai, Y; Tomioka, K; Yamada, T | 1 |
Cruz, C; Hernández, C; Ibarra-Rubio, ME; Pedraza-Chaverrí, J; Peña, JC; Tapia, E | 1 |
Del Pizzo, R; Gauthier, B; Trachtman, H; Valderrama, E | 1 |
Diamond, JR; Hanchak, NA; Karnovsky, MJ; McCarter, MD | 1 |
Anderson, S; Brenner, BM; Diamond, JR; Karnovsky, MJ | 1 |
Hill, GS | 1 |
Adler, S; Baker, PJ; Couser, WG; Johnson, RJ; Perkinson, DT | 1 |
Chandrachud, L; Jones, JM | 1 |
Elema, JD; Grond, J; Weening, JJ | 1 |
Elema, JD; Grond, J; van Goor, H; Weening, JJ | 1 |
Atkins, RC; Glasgow, EF; Saito, T; Sumithran, E | 1 |
Fogo, A; Glick, AD; Homma, T; Ichikawa, I; Yoshida, Y | 1 |
Bonventre, JV; Diamond, JR; Karnovsky, MJ | 1 |
5 review(s) available for puromycin aminonucleoside and Disease Models, Animal
Article | Year |
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Models of glomerulonephritis.
Topics: Animals; Crotalid Venoms; Disease Models, Animal; Doxorubicin; Glomerulonephritis; Humans; Puromycin Aminonucleoside; Trimeresurus | 2003 |
Taurine and experimental kidney disease.
Topics: Animals; Cell Division; Cell Line; Diabetic Nephropathies; Disease Models, Animal; Kidney Diseases; Puromycin Aminonucleoside; Taurine | 1994 |
An evaluation of experimental models of glomerulonephritis.
Topics: Animals; Antigen-Antibody Complex; Autoimmune Diseases; Disease Models, Animal; Evaluation Studies as Topic; Glomerulonephritis; Glomerulonephritis, IGA; Glomerulosclerosis, Focal Segmental; Humans; Mice; Nephrosis, Lipoid; Puromycin Aminonucleoside; Serum Sickness; Species Specificity | 1994 |
Focal glomerular hyalinosis and sclerosis in aminonucleoside and adriamycin nephrosis: pathogenetic and therapeutic considerations.
Topics: Animals; Disease Models, Animal; Doxorubicin; Glomerular Mesangium; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Nephrotic Syndrome; Puromycin Aminonucleoside; Rats | 1988 |
Application of puromycin aminonucleoside and adriamycin to induce chronic renal failure in the rat.
Topics: Animals; Disease Models, Animal; Doxorubicin; Kidney Failure, Chronic; Puromycin; Puromycin Aminonucleoside; Rats | 1988 |
117 other study(ies) available for puromycin aminonucleoside and Disease Models, Animal
Article | Year |
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Decreased Podocyte Vesicle Transcytosis and Albuminuria in
Topics: Adenomatous Polyposis Coli; Albuminuria; Animals; Disease Models, Animal; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Nephrotic Syndrome; Podocytes; Puromycin; Puromycin Aminonucleoside; Transcytosis | 2021 |
Hirudin attenuates puromycin aminonucleoside-induced glomerular podocyte injury by inhibiting MAPK-mediated endoplasmic reticulum stress.
Topics: Animals; Cytoskeletal Proteins; Disease Models, Animal; Endoplasmic Reticulum Stress; Hirudins; Kidney Diseases; Mice; p38 Mitogen-Activated Protein Kinases; Podocytes; Puromycin Aminonucleoside | 2022 |
Sertraline Reduces Albuminuria by Interfering with Caveolae-Mediated Endocytosis through Glomerular Endothelial and Epithelial Cells.
Topics: Albumins; Albuminuria; Animals; Caveolae; Caveolin 1; Cells, Cultured; Disease Models, Animal; Dynamins; Endocytosis; Endothelial Cells; Humans; Male; Mice; Nephrotic Syndrome; Podocytes; Primary Cell Culture; Puromycin Aminonucleoside; Sertraline | 2019 |
Repository corticotropin injection versus corticosteroids for protection against renal damage in a focal segmental glomerulosclerosis rodent model.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Biomarkers; Disease Models, Animal; Female; Fibrosis; Glomerulosclerosis, Focal Segmental; Injections; Kidney; Membrane Glycoproteins; Podocytes; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley | 2020 |
Decreased Excretion of Urinary Exosomal Aquaporin-2 in a Puromycin Aminonucleoside-Induced Nephrotic Syndrome Model.
Topics: Animals; Aquaporin 2; Biomarkers; Disease Models, Animal; Down-Regulation; Exosomes; Injections, Intraperitoneal; Male; Nephrotic Syndrome; Puromycin Aminonucleoside; Rats | 2020 |
Dysfunction of the Klotho-miR-30s/TRPC6 axis confers podocyte injury.
Topics: Animals; Calcium Signaling; Cells, Cultured; Dexamethasone; Disease Models, Animal; Down-Regulation; Glucuronidase; Humans; Kidney Diseases; Klotho Proteins; Male; MicroRNAs; Podocytes; Puromycin Aminonucleoside; Rats; Rats, Wistar; TRPC6 Cation Channel | 2021 |
The relationship between glomerular function and podocyte structure of pre-proteinuria and acute nephrosis in puromycin aminonucleoside-induced rat models: a comparative electron microscopic study.
Topics: Animals; Disease Models, Animal; Kidney Glomerulus; Male; Microscopy, Electron; Nephrosis; Podocytes; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar | 2017 |
Antiproteinuric effect of an endothelin-1 receptor antagonist in puromycin aminonucleoside-induced nephrosis in rat.
Topics: Animals; B7-1 Antigen; Blood Pressure; Body Weight; Creatinine; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin-1; Female; Kidney; Kidney Diseases; Kidney Glomerulus; Nephrosis; Nephrotic Syndrome; NF-kappa B; Phenylpropionates; Podocytes; Proteinuria; Puromycin Aminonucleoside; Pyridazines; Rats; Rats, Wistar; Receptor, Endothelin A; Toll-Like Receptor 3 | 2018 |
Expression of Cathepsin L and Its Intrinsic Inhibitors in Glomeruli of Rats With Puromycin Aminonucleoside Nephrosis.
Topics: Animals; Cathepsin L; Cystatin B; Cystatin C; Disease Models, Animal; Immunohistochemistry; Kidney Glomerulus; Male; Nephrotic Syndrome; Podocytes; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley | 2018 |
Each liver X receptor (LXR) type has a different purpose in different situations.
Topics: Animals; Cell Line; Disease Models, Animal; Gene Knockdown Techniques; Kidney; Lipid Metabolism; Liver X Receptors; Male; Nephrosis, Lipoid; Puromycin Aminonucleoside; Rats; Rats, Wistar; RNA, Messenger | 2019 |
Morphological Processes of Foot Process Effacement in Puromycin Aminonucleoside Nephrosis Revealed by FIB/SEM Tomography.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Glomerular Basement Membrane; Imaging, Three-Dimensional; Injections, Intraperitoneal; Male; Microscopy, Electron, Scanning; Nephrosis; Podocytes; Puromycin Aminonucleoside; Random Allocation; Rats; Rats, Wistar; Reference Values; Tomography, X-Ray Computed | 2019 |
Estrogen-related receptor-α mediates puromycin aminonucleoside-induced mesangial cell apoptosis and inflammatory injury.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Disease Models, Animal; Estrogen Receptor alpha; Male; Mice; Nephrosis; Podocytes; Puromycin Aminonucleoside; Rats, Sprague-Dawley; Signal Transduction | 2019 |
Signal regulatory protein α protects podocytes through promoting autophagic activity.
Topics: Adolescent; Adult; Aged; Animals; Antigens, Differentiation; Autophagy; Biopsy; Disease Models, Animal; Down-Regulation; Doxorubicin; Female; Glomerular Basement Membrane; Glomerulosclerosis, Focal Segmental; Humans; Male; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Middle Aged; Phosphorylation; Podocytes; Proteinuria; Proto-Oncogene Proteins c-akt; Puromycin Aminonucleoside; Receptors, Immunologic; Severity of Illness Index; Signal Transduction; Streptozocin; Young Adult | 2019 |
Downregulation of microRNA-30 facilitates podocyte injury and is prevented by glucocorticoids.
Topics: Animals; Cells, Cultured; Dexamethasone; Disease Models, Animal; Down-Regulation; Gene Knockdown Techniques; Glomerulosclerosis, Focal Segmental; Glucocorticoids; Humans; Lipopolysaccharides; MicroRNAs; Podocytes; Puromycin Aminonucleoside; Rats; Rats, Wistar; Receptor, Notch1; Transforming Growth Factor beta; Tumor Suppressor Protein p53 | 2014 |
Podocyte autophagic activity plays a protective role in renal injury and delays the progression of podocytopathies.
Topics: Acute Kidney Injury; Animals; Apoptosis; Autophagy; Disease Models, Animal; Disease Progression; Female; Glomerulosclerosis, Focal Segmental; Humans; Male; Podocytes; Proteinuria; Puromycin Aminonucleoside; Rats, Wistar | 2014 |
Do large pores in the glomerular capillary wall account for albuminuria in nephrotic states?
Topics: Albuminuria; Animals; Capillaries; Carbon Radioisotopes; Cell Membrane Permeability; Disease Models, Animal; Ficoll; Glomerular Filtration Rate; Hydrodynamics; Immunoglobulin G; Kidney Glomerulus; Male; Nephrosis; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley | 2014 |
GIV/girdin links vascular endothelial growth factor signaling to Akt survival signaling in podocytes independent of nephrin.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Cells, Cultured; Disease Models, Animal; GTP-Binding Protein alpha Subunits, Gi-Go; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Microfilament Proteins; Nephrosis; Phosphatidylinositol 3-Kinases; Podocytes; Proto-Oncogene Proteins c-akt; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Signal Transduction; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A | 2015 |
Angiotensin II type 1 receptor blockade ameliorates proteinuria in puromycin aminonucleoside nephropathy by inhibiting the reduction of NEPH1 and nephrin.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Disease Models, Animal; Disease Progression; Female; Gene Expression Regulation; Intracellular Signaling Peptides and Proteins; Irbesartan; Kidney Glomerulus; Membrane Proteins; Nephrosis, Lipoid; Proteinuria; Puromycin Aminonucleoside; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles; Time Factors | 2014 |
Quantitative analysis of markers of podocyte injury in the rat puromycin aminonucleoside nephropathy model.
Topics: Animals; Biomarkers; Disease Models, Animal; Image Processing, Computer-Assisted; Immunohistochemistry; Kidney Diseases; Male; Microscopy, Fluorescence; Podocytes; Puromycin Aminonucleoside; Rats, Sprague-Dawley; RNA, Messenger | 2015 |
Disease Severity Correlates with Thrombotic Capacity in Experimental Nephrotic Syndrome.
Topics: Animals; Antithrombins; Biomarkers; Blood Coagulation; Blood Coagulation Disorders; Disease Models, Animal; Doxorubicin; Elasticity; Fibrinogen; Hemostasis; Hypoalbuminemia; Male; Nephrotic Syndrome; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar; Serum Albumin; Severity of Illness Index; Thrombin; Thrombosis | 2015 |
Identification of Promising Urinary MicroRNA Biomarkers in Two Rat Models of Glomerular Injury.
Topics: Acute Kidney Injury; Animals; Biomarkers; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Glomerulonephritis, Membranous; Heymann Nephritis Antigenic Complex; Immune Sera; Kidney Glomerulus; Laser Capture Microdissection; Male; Metabolomics; MicroRNAs; Microscopy, Electron, Transmission; Oxidative Stress; Podocytes; Puromycin Aminonucleoside; Rats, Sprague-Dawley; Sheep, Domestic | 2015 |
The Expression Profile of Complement Components in Podocytes.
Topics: Angiotensin II; Animals; Carrier Proteins; Cells, Cultured; Complement System Proteins; Diabetic Nephropathies; Disease Models, Animal; Humans; Interleukin-6; Male; Microfilament Proteins; Microscopy, Confocal; Podocytes; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Tandem Mass Spectrometry; Transcriptome; Transforming Growth Factor beta | 2016 |
The Prediction of Key Cytoskeleton Components Involved in Glomerular Diseases Based on a Protein-Protein Interaction Network.
Topics: Animals; Biomarkers; Cytoskeleton; Diabetic Nephropathies; Disease Models, Animal; Gene Regulatory Networks; Humans; Kidney Diseases; Kidney Glomerulus; Male; Protein Interaction Maps; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley | 2016 |
Angiotensin converting-enzyme inhibition restores glomerular glycosaminoglycans in rat puromycin nephrosis.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Enalapril; Glycosaminoglycans; Immunohistochemistry; Kidney Glomerulus; Male; Microscopy, Electron, Transmission; Nephrosis; Podocytes; Protein Synthesis Inhibitors; Puromycin Aminonucleoside; Rats; Rats, Wistar | 2016 |
Intracellular transcytosis of albumin in glomerular endothelial cells after endocytosis through caveolae.
Topics: Albuminuria; Animals; beta-Cyclodextrins; Caveolae; Caveolin 1; Cells, Cultured; Disease Models, Animal; Endocytosis; Endosomes; Endothelial Cells; Humans; Kidney Glomerulus; Male; Mice, Inbred C57BL; Nephrosis; Puromycin Aminonucleoside; Serum Albumin, Bovine; Time Factors; Transcytosis | 2017 |
Protective effects of antithrombin on puromycin aminonucleoside nephrosis in rats.
Topics: Animals; Anticoagulants; Antithrombins; Apoptosis; Blood Coagulation; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Hyperlipidemias; In Situ Nick-End Labeling; Injections, Intravenous; Kidney; Nephrotic Syndrome; Proteinuria; Puromycin Aminonucleoside; Rats; Thrombin; Time Factors | 2008 |
Contribution of down-regulation of intestinal and hepatic cytochrome P450 3A to increased absorption of cyclosporine A in a rat nephrosis model.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Disease Models, Animal; Down-Regulation; Interleukin-6; Intestines; Liver; Male; Nephrosis; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2008 |
Nck proteins maintain the adult glomerular filtration barrier.
Topics: Adaptor Proteins, Signal Transducing; Animals; Anti-Bacterial Agents; Cell Line; Disease Models, Animal; Doxycycline; Glomerular Filtration Rate; Glomerulonephritis; Kidney Glomerulus; Male; Membrane Proteins; Mice; Mice, Transgenic; Oncogene Proteins; Phosphorylation; Podocytes; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Tight Junctions | 2009 |
Effects of mineralocorticoid and angiotensin II receptor blockers on proteinuria and glomerular podocyte protein expression in a model of minimal change nephrotic syndrome.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Disease Models, Animal; Eplerenone; Fluorescent Antibody Technique; Intracellular Signaling Peptides and Proteins; Losartan; Male; Membrane Proteins; Mineralocorticoid Receptor Antagonists; Nephrosis, Lipoid; Podocytes; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Spironolactone; Time Factors | 2010 |
Semi-automated quantitative image analysis of podocyte desmin immunoreactivity as a sensitive marker for acute glomerular damage in the rat puromycin aminonucleoside nephrosis (PAN) model.
Topics: Acute Disease; Animals; Biomarkers; Desmin; Disease Models, Animal; Dose-Response Relationship, Drug; Image Interpretation, Computer-Assisted; Immunohistochemistry; Kidney Function Tests; Male; Nephrosis; Podocytes; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2012 |
Impaired glomerular and tubular antioxidative defense mechanisms in nephrotic syndrome.
Topics: Adult; Aged; Animals; Antioxidants; Biopsy; Case-Control Studies; Catalase; Disease Models, Animal; Female; Glomerular Filtration Rate; Glutathione Peroxidase; Humans; Kidney Glomerulus; Kidney Tubules; Lipid Peroxidation; Male; Middle Aged; Nephrotic Syndrome; Oxidative Stress; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Thioredoxin-Disulfide Reductase | 2010 |
Expression and localization of insulin-like growth factor binding proteins in normal and proteinuric kidney glomeruli.
Topics: Animals; Biopsy; Case-Control Studies; Disease Models, Animal; Female; Gene Expression Profiling; Humans; In Situ Hybridization; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Kidney Glomerulus; Oligonucleotide Array Sequence Analysis; Podocytes; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred WKY; Receptor, IGF Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2010 |
Induction of podocyte-derived VEGF ameliorates podocyte injury and subsequent abnormal glomerular development caused by puromycin aminonucleoside.
Topics: Actinin; Animals; Animals, Newborn; Apoptosis; Autocrine Communication; bcl-2-Associated X Protein; bcl-X Protein; Caspase 3; Cells, Cultured; Desmin; Disease Models, Animal; Doxycycline; Glomerulonephritis; Humans; Intracellular Signaling Peptides and Proteins; Kidney Glomerulus; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; Podocytes; Puromycin Aminonucleoside; Response Elements; Vascular Endothelial Growth Factor A | 2011 |
Inhibition of the protein kinase MK-2 protects podocytes from nephrotic syndrome-related injury.
Topics: Animals; Cell Line; Disease Models, Animal; Heat-Shock Proteins; Imidazoles; Intracellular Signaling Peptides and Proteins; Mice; Molecular Chaperones; Neoplasm Proteins; Nephrotic Syndrome; p38 Mitogen-Activated Protein Kinases; Podocytes; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Puromycin Aminonucleoside; Pyridines; Serum Albumin; Signal Transduction | 2011 |
Renoprotective potential of Macrothelypteris torresiana via ameliorating oxidative stress and proinflammatory cytokines.
Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Creatinine; Diet, High-Fat; Disease Models, Animal; Drugs, Chinese Herbal; Ferns; Hyperlipidemias; Kidney; Lipid Peroxidation; Lipids; Male; Mice; Nephrotic Syndrome; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Phytotherapy; Polyphenols; Potassium Dichromate; Protective Agents; Puromycin Aminonucleoside; Vascular Endothelial Growth Factor A | 2012 |
Experimentally induced puromycine aminonucleoside nephrosis (PAN) in rats: evaluation of angiogenic protein platelet-derived endothelial cell growth factor (PD-ECGF) expression in glomeruli.
Topics: Acute Disease; Albumins; Angiogenic Proteins; Animals; Chronic Disease; Creatinine; Disease Models, Animal; Humans; Hypoxia; Immunohistochemistry; Injections, Subcutaneous; Kidney Glomerulus; Male; Microscopy, Electron, Transmission; Neovascularization, Pathologic; Nephrosis; Platelet-Derived Growth Factor; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar | 2012 |
Role of cytochrome P450 2B1 in puromycin aminonucleoside-induced cytotoxicity to glomerular epithelial cells.
Topics: Animals; Cells, Cultured; Cimetidine; Cytochrome P-450 CYP2B1; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Epithelial Cells; Heme Oxygenase (Decyclizing); Humans; Hydrogen Peroxide; Immunohistochemistry; Kidney Diseases; Kidney Glomerulus; Nephrotic Syndrome; Pilot Projects; Puromycin Aminonucleoside; Rats; Reactive Oxygen Species; Time Factors | 2003 |
Retinoids as a potential treatment for experimental puromycin-induced nephrosis.
Topics: Administration, Oral; Animals; Apoptosis; Cell Culture Techniques; Cell Movement; Chemokine CCL2; Disease Models, Animal; Drug Combinations; Epithelial Cells; Female; Fibronectins; Food; Injections, Intraperitoneal; Kidney Glomerulus; Leukocytes, Mononuclear; Mice; Nephrosis; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar; Retinoids; Time Factors | 2003 |
A study of VEGF and its receptors in two rat models of proteinuria.
Topics: Albuminuria; Animals; Cell Line; Disease Models, Animal; Glomerulonephritis; Immunohistochemistry; Kidney Glomerulus; Male; Nephrosis; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Receptors, Vascular Endothelial Growth Factor; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2004 |
Altered expression of NDST-1 messenger RNA in puromycin aminonucleoside nephrosis.
Topics: Amidohydrolases; Animals; Base Sequence; Basement Membrane; Cells, Cultured; Cholesterol; Creatinine; Disease Models, Animal; DNA Primers; Gene Expression Regulation; Kidney Glomerulus; Male; Nephrosis; Polymerase Chain Reaction; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar; RNA, Messenger; Sulfotransferases | 2004 |
Protection against puromycin aminonucleoside-induced chronic renal disease in the Wistar-Furth rat.
Topics: Animals; Antimetabolites, Antineoplastic; Disease Models, Animal; Glomerular Filtration Rate; Kidney Failure, Chronic; Kidney Medulla; Male; Nitric Oxide; Nitric Oxide Synthase; Puromycin Aminonucleoside; Rats; Rats, Inbred WF | 2004 |
Key molecular events in puromycin aminonucleoside nephrosis rats.
Topics: Actinin; Animals; Antibiotics, Antineoplastic; Disease Models, Animal; Intracellular Signaling Peptides and Proteins; Kidney Glomerulus; Male; Membrane Proteins; Nephrosis; Proteins; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Ultrastructural study on nephrin expression in experimental puromycin aminonucleoside nephrosis.
Topics: Animals; Disease Models, Animal; Kidney; Kidney Glomerulus; Male; Membrane Proteins; Microscopy, Immunoelectron; Nephrosis; Proteins; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley | 2004 |
Role of uroguanylin, a Peptide with natriuretic activity, in rats with experimental nephrotic syndrome.
Topics: Animals; Atrial Natriuretic Factor; Base Sequence; Biomarkers; Disease Models, Animal; Male; Molecular Sequence Data; Natriuresis; Natriuretic Peptides; Nephrotic Syndrome; Peptides; Probability; Puromycin Aminonucleoside; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
Reduced activity of 11beta-hydroxysteroid dehydrogenase type 2 is not responsible for sodium retention in nephrotic rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Corticosterone; Dexamethasone; Disease Models, Animal; Down-Regulation; Feces; Glucocorticoids; Kidney Cortex; Male; Nephrotic Syndrome; Phosphorylation; Potassium; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium; Up-Regulation | 2005 |
Role of p38 mitogen-activated protein kinase activation in podocyte injury and proteinuria in experimental nephrotic syndrome.
Topics: Actins; Animals; Cells, Cultured; Disease Models, Animal; Doxorubicin; Enzyme Activation; Glomerulosclerosis, Focal Segmental; Humans; Male; Mice; Nephrotic Syndrome; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Podocytes; Protein Kinase Inhibitors; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred WKY | 2005 |
Increased expression of apoptosis-associated proteins in puromycin aminonucleoside nephrosis.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Disease Models, Animal; Fas Ligand Protein; fas Receptor; Male; Membrane Glycoproteins; Nephrosis; Proto-Oncogene Proteins c-bcl-2; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Receptors, Tumor Necrosis Factor; Tumor Suppressor Protein p53 | 2005 |
Beneficial effects of orosomucoid on the glomerular barrier in puromycin aminonucleoside-induced nephrosis.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Disease Models, Animal; Female; Glomerular Filtration Rate; Immunohistochemistry; Kidney Glomerulus; Nephrosis; Orosomucoid; Probability; Puromycin Aminonucleoside; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity | 2006 |
Upregulation of nestin, vimentin, and desmin in rat podocytes in response to injury.
Topics: Animals; Blotting, Western; Desmin; Disease Models, Animal; Female; Injections, Intravenous; Intermediate Filament Proteins; Microscopy, Immunoelectron; Nephrosis; Nerve Tissue Proteins; Nestin; Podocytes; Puromycin Aminonucleoside; Rats; Rats, Inbred WKY; Rats, Wistar; RNA, Messenger; Up-Regulation; Vimentin | 2006 |
Fluvastatin ameliorates podocyte injury in proteinuric rats via modulation of excessive Rho signaling.
Topics: Acute-Phase Proteins; Analysis of Variance; Animals; Blotting, Western; Disease Models, Animal; Fatty Acids, Monounsaturated; Fluvastatin; Immunohistochemistry; Indoles; Male; Podocytes; Probability; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Signal Transduction | 2006 |
Differential nephron HO-1 expression following glomerular epithelial cell injury.
Topics: Animals; Cyclic N-Oxides; Disease Models, Animal; Free Radical Scavengers; Heme Oxygenase-1; Kidney Glomerulus; Male; Nephrons; Nitrogen Oxides; Permeability; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Up-Regulation | 2006 |
Morphologic, molecular and hemodynamic cardiac alterations in a model of nephropathy induced by puromycin aminonucleoside.
Topics: Animals; Disease Models, Animal; Hemodynamics; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Renal Insufficiency | 2006 |
Podocyte protection by darbepoetin: preservation of the cytoskeleton and nephrin expression.
Topics: Actins; Animals; Apoptosis; B7-1 Antigen; Cells, Cultured; Cytoskeleton; Darbepoetin alfa; Desmin; Disease Models, Animal; Dose-Response Relationship, Drug; Erythropoietin; In Situ Nick-End Labeling; Male; Membrane Proteins; Nephrotic Syndrome; Podocytes; Protective Agents; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptors, Erythropoietin; RNA, Messenger; Time Factors | 2007 |
Darbepoetin alfa protects podocytes from apoptosis in vitro and in vivo.
Topics: Animals; Antibodies; Apoptosis; Autoantibodies; Cell Proliferation; Cells, Cultured; Darbepoetin alfa; Disease Models, Animal; Disease Progression; Erythropoietin; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Janus Kinase 2; Mice; Podocytes; Protective Agents; Proteinuria; Proto-Oncogene Proteins c-akt; Puromycin Aminonucleoside; Receptors, Erythropoietin; Signal Transduction; Transforming Growth Factor beta1; Ultraviolet Rays | 2007 |
In vivo detection of intrinsic reactive oxygen species using acyl-protected hydroxylamine in puromycin nephrosis.
Topics: Animals; Catalase; Dimethyl Sulfoxide; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Hydroxylamine; Kinetics; Nephrosis; Puromycin Aminonucleoside; Pyrrolidines; Rats; Reactive Oxygen Species; Superoxide Dismutase | 2007 |
The renal clearance of dextran sulfate decreases in puromycin aminonucleoside-induced glomerulosclerosis: a puzzle observation.
Topics: Animals; Dextran Sulfate; Disease Models, Animal; Glomerulosclerosis, Focal Segmental; Heparin; Kidney; Metabolic Clearance Rate; Polysaccharides; Puromycin Aminonucleoside; Rats | 2007 |
Increased cyclosporine bioavailability induced by experimental nephrotic syndrome in rats.
Topics: Animals; Area Under Curve; Biological Availability; Cholesterol; Cyclosporine; Disease Models, Animal; Half-Life; Hypercholesterolemia; Hypertriglyceridemia; Hypoalbuminemia; Immunosuppressive Agents; Injections, Subcutaneous; Male; Metabolic Clearance Rate; Nephrotic Syndrome; Puromycin Aminonucleoside; Rats; Rats, Wistar | 2007 |
Beneficial effects of the Rho kinase inhibitor Y27632 in murine puromycin aminonucleoside nephrosis.
Topics: Amides; Animals; Antihypertensive Agents; Cells, Cultured; Disease Models, Animal; Epithelial Cells; Kidney Glomerulus; Membrane Proteins; Mice; Nephrosis; Podocytes; Puromycin Aminonucleoside; Pyridines; rho-Associated Kinases | 2008 |
Urinary excretion of alpha 2 mu-globulin and albumin by adult male rats following treatment with nephrotoxic agents.
Topics: Albumins; Albuminuria; Alpha-Globulins; Animals; Dietary Proteins; Disease Models, Animal; Female; Male; Maleates; Proteinuria; Puromycin; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains | 1981 |
Focal glomerular sclerosis in aminonucleoside nephropathy.
Topics: Animals; Disease Models, Animal; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Hyalin; Kidney Glomerulus; Male; Puromycin; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains | 1981 |
Modulation of Ia and leukocyte common antigen expression in rat glomeruli during the course of glomerulonephritis and aminonucleoside nephrosis.
Topics: Animals; Basement Membrane; Complement System Proteins; Disease Models, Animal; Female; Fluorescent Antibody Technique; Glomerular Mesangium; Glomerulonephritis; Histocompatibility Antigens; Histocompatibility Antigens Class II; Immune Sera; Kidney Diseases; Kidney Glomerulus; Leukocyte Common Antigens; Puromycin Aminonucleoside; Rats; Rats, Inbred Lew | 1984 |
An ultrastructural study of the effect of the steroid in puromycin aminonucleoside nephrosis rats.
Topics: Animals; Disease Models, Animal; Kidney Glomerulus; Male; Methylprednisolone; Microscopy, Electron; Nephrosis, Lipoid; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains | 1984 |
Secretion of lipoproteins, apolipoprotein A-I and apolipoprotein E by isolated and perfused liver of rat with experimental nephrotic syndrome.
Topics: Animals; Apolipoprotein A-I; Apolipoproteins; Apolipoproteins E; Disease Models, Animal; In Vitro Techniques; Kinetics; Lipoproteins; Liver; Male; Nephrotic Syndrome; Perfusion; Puromycin Aminonucleoside; Rats | 1981 |
Puromycin aminonucleoside inhibits mesangial cell-induced contraction of collagen gels by stimulating production of reactive oxygen species.
Topics: Amitrole; Animals; Catalase; Collagen; Culture Techniques; Disease Models, Animal; Extracellular Matrix; Gels; Glomerular Mesangium; Male; Nephrosis; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 1995 |
Induction of proteinuria by adriamycin or bovine serum albumin in the mouse.
Topics: Animals; Creatinine; Disease Models, Animal; Doxorubicin; Female; Glomerular Mesangium; Injections, Intravenous; Kidney; Mice; Mice, Inbred BALB C; Microscopy; Proteinuria; Puromycin Aminonucleoside; Serum Albumin, Bovine | 1995 |
Time course of lipid peroxidation in puromycin aminonucleoside-induced nephropathy.
Topics: Animals; Disease Models, Animal; Female; Injections, Intravenous; Kidney Cortex; Lipid Peroxidation; Nephrosis; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Time Factors | 1994 |
Effects of glycyrrhetinic acid on aminonucleoside nephrosis in rats.
Topics: Animals; Blood Proteins; Cholesterol; Disease Models, Animal; Female; Glycyrrhetinic Acid; Kidney; Lipid Peroxides; Microscopy, Electron; Nephrosis; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar | 1994 |
Extracellular matrix component mRNA expression in glomeruli in experimental focal glomerulosclerosis.
Topics: Animals; Collagen; Disease Models, Animal; Extracellular Matrix; Extracellular Matrix Proteins; Gene Expression; Glomerulosclerosis, Focal Segmental; Heparan Sulfate Proteoglycans; Heparitin Sulfate; Kidney Glomerulus; Laminin; Male; Nephrectomy; Proteoglycans; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1993 |
Noninvasive microscopic evaluation of the intact living nephrotic kidney.
Topics: Animals; Disease Models, Animal; Fluorescent Dyes; Glomerular Filtration Rate; Kidney; Kidney Tubules; Male; Microscopy, Fluorescence; Nephrosis; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar | 1993 |
Time course analysis of serum and urinary proteins by SDS-PAGE in experimental nephrotic syndrome.
Topics: Analysis of Variance; Animals; Blood Proteins; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Hypoproteinemia; Male; Molecular Weight; Nephrotic Syndrome; Polyuria; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar; Time Factors | 1996 |
Role of 'catalytic' iron in an animal model of minimal change nephrotic syndrome.
Topics: Animals; Bleomycin; Deferoxamine; Disease Models, Animal; Iron; Kidney Glomerulus; Kidney Tubules; Male; Nephrotic Syndrome; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Siderophores | 1996 |
The effect of recombinant human insulin-like growth factor-I on chronic puromycin aminonucleoside nephropathy in rats.
Topics: Animals; Blood Glucose; Blood Pressure; Chronic Disease; Disease Models, Animal; Humans; Insulin; Insulin-Like Growth Factor I; Kidney Diseases; Kidney Glomerulus; Male; Malondialdehyde; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Recombinant Proteins; Weight Gain | 1996 |
Inhibition of progression of chronic puromycin aminonucleoside nephrosis by probucol, an antioxidant.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Chronic Disease; Disease Models, Animal; Disease Progression; Follow-Up Studies; Immunohistochemistry; Infusions, Intravenous; Kidney Glomerulus; Lipid Metabolism; Male; Nephrotic Syndrome; Probucol; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley | 1996 |
Myofibroblast and alpha 1 (III) collagen expression in experimental tubulointerstitial nephritis.
Topics: Actins; Animals; Autoradiography; Becaplermin; Collagen; Disease Models, Animal; Fibroblasts; Gene Expression; Immunohistochemistry; In Situ Hybridization; Nephritis, Interstitial; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Puromycin Aminonucleoside; Rats; Rats, Inbred Lew; RNA, Messenger | 1997 |
On the interrelationship between hepatic carnitine, fatty acid oxidation, and triglyceride biosynthesis in nephrosis.
Topics: Acetyl Coenzyme A; Animals; Carnitine; Cholesterol; Cytosol; Disease Models, Animal; Fatty Acids; Lipid Metabolism; Lipids; Lipoproteins, VLDL; Liver; Male; Mitochondria, Liver; Nephrotic Syndrome; Oxidation-Reduction; Phosphatidate Phosphatase; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Triglycerides | 1997 |
Structure-activity relationship for two lipoxygenase inhibitors and their potential for inducing nephrotic syndrome.
Topics: Administration, Oral; Animals; Antibiotics, Antineoplastic; Blood Proteins; Cholesterol; Creatinine; Disease Models, Animal; Female; Hydroxamic Acids; Hydroxyurea; Kidney Glomerulus; Lipoxygenase Inhibitors; Nephrosis, Lipoid; Nephrotic Syndrome; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar; Structure-Activity Relationship; Triglycerides; Urinalysis | 1997 |
Reactive oxygen species and antioxidant defense in puromycin aminonucleoside glomerulopathy.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Catalase; Culture Techniques; Disease Models, Animal; Glomerulonephritis, Membranous; Glutathione Peroxidase; Male; Microscopy, Electron; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reference Values; RNA, Messenger; Superoxide Dismutase | 1997 |
Gene expression of lipoprotein lipase in experimental nephrosis.
Topics: Adipose Tissue; Animals; Blotting, Northern; Blotting, Western; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Enzymologic; Hypertriglyceridemia; Lipoprotein Lipase; Lipoproteins; Male; Muscle, Skeletal; Myocardium; Nephrotic Syndrome; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; RNA, Messenger; Triglycerides | 1997 |
Effects of recombinant human serum albumin on ascites in rats with puromycin aminonucleoside-induced nephropathy.
Topics: Animals; Ascites; Disease Models, Animal; Diuretics; Drug Evaluation, Preclinical; Furosemide; Humans; Male; Nephrosis, Lipoid; Osmotic Pressure; Puromycin Aminonucleoside; Rats; Rats, Wistar; Recombinant Proteins; Serum Albumin | 1998 |
MR imaging of intrarenal macrophage infiltration in an experimental model of nephrotic syndrome.
Topics: Animals; Contrast Media; Dextrans; Disease Models, Animal; Ferrosoferric Oxide; Follow-Up Studies; Injections, Intravenous; Iron; Kidney Cortex; Kidney Medulla; Macrophages; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Nephrotic Syndrome; Oxides; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley | 1999 |
Heparin-binding epidermal growth factor-like growth factor is expressed in the adhesive lesions of experimental focal glomerular sclerosis.
Topics: Actins; Animals; Creatinine; Disease Models, Animal; Epidermal Growth Factor; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Heparin-binding EGF-like Growth Factor; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Macrophages; Male; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation | 1999 |
Gene expression of CC chemokines in experimental acute tubulointerstitial nephritis.
Topics: Acute Disease; Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chemokines, CC; Disease Models, Animal; DNA Primers; DNA Probes; Gene Expression; Kidney Cortex; Leukocyte Count; Male; Monocytes; Nephritis, Interstitial; Nephrosis; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Protection of alpha(3) integrin-mediated podocyte shape by superoxide dismutase in the puromycin aminonucleoside nephrosis rat.
Topics: Animals; Antibiotics, Antineoplastic; Antigens, CD; Cell Adhesion; Cell Count; Cell Membrane; Cell Membrane Permeability; Disease Models, Animal; Epithelial Cells; Free Radical Scavengers; Half-Life; Humans; Integrin alpha3; Integrins; Kidney Glomerulus; Kidney Tubules; Luminescent Measurements; Male; Microscopy, Confocal; Microvilli; Nephrosis; Phosphatidylcholines; Protective Agents; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar; Reactive Oxygen Species; Recombinant Proteins; Superoxide Dismutase | 2000 |
Nephrin in experimental glomerular disease.
Topics: Albuminuria; Animals; Antimetabolites, Antineoplastic; Disease Models, Animal; Disinfectants; Gene Expression; Glomerulonephritis; Kidney Glomerulus; Lipid Peroxidation; Male; Membrane Proteins; Mercuric Chloride; Microscopy, Immunoelectron; Proteins; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic | 2000 |
Garlic ameliorates hyperlipidemia in chronic aminonucleoside nephrosis.
Topics: Animals; Catalase; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Chronic Disease; Disease Models, Animal; Garlic; Glutathione Peroxidase; Hydrogen Peroxide; Hyperlipidemias; Hypolipidemic Agents; Kidney; Male; Nephrotic Syndrome; Phytotherapy; Plants, Medicinal; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar; Superoxide Dismutase; Triglycerides | 2000 |
Hepatic histidase and muscle branched chain aminotransferase gene expression in experimental nephrosis.
Topics: Animals; Body Weight; Disease Models, Animal; Energy Intake; Gene Expression Regulation, Enzymologic; Histidine Ammonia-Lyase; Humans; Liver; Male; Muscle, Skeletal; Nephrotic Syndrome; Puromycin Aminonucleoside; Rats; Rats, Wistar; RNA, Messenger; Transaminases; Transcription, Genetic | 2000 |
Puromycin aminonucleoside induces glomerular epithelial cell apoptosis.
Topics: Animals; Apoptosis; Catalase; Cells, Cultured; Dactinomycin; Disease Models, Animal; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Epithelial Cells; Free Radical Scavengers; Humans; In Situ Nick-End Labeling; Kidney Glomerulus; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiourea | 2001 |
Urine laminin and kallikrein, markers of tubulointerstitial damage in experimental protein overload on pre-existing renal damage.
Topics: Animals; Biomarkers; Butadienes; Disease Models, Animal; Kallikreins; Kidney; Laminin; Male; Nephritis, Interstitial; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Urinalysis | 2001 |
Plasma and urinary endothelin-1 in focal segmental glomerulosclerosis.
Topics: Adult; Animals; Disease Models, Animal; Endothelin-1; Female; Glomerulosclerosis, Focal Segmental; Humans; Injections, Subcutaneous; Male; Puromycin Aminonucleoside; Rats; Rats, Wistar | 2001 |
Downregulation of vascular endothelial growth factor and its receptors in the kidney in rats with puromycin aminonucleoside nephrosis.
Topics: Animals; Antibiotics, Antineoplastic; Disease Models, Animal; Down-Regulation; Endothelial Growth Factors; Humans; In Situ Hybridization; Kidney; Lymphokines; Male; Nephrosis, Lipoid; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
GLEPP1 receptor tyrosine phosphatase (Ptpro) in rat PAN nephrosis. A marker of acute podocyte injury.
Topics: Animals; Antibiotics, Antineoplastic; Biomarkers; Disease Models, Animal; Epithelial Cells; Kidney Glomerulus; Male; Membrane Proteins; Nephrosis; Protein Tyrosine Phosphatases; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Receptor-Like Protein Tyrosine Phosphatases, Class 3 | 2002 |
Podocyte-associated molecules in puromycin aminonucleoside nephrosis of the rat.
Topics: Actinin; Albuminuria; Animals; beta Catenin; Cytoskeletal Proteins; Disease Models, Animal; DNA Primers; Dystroglycans; Female; Immunohistochemistry; Integrin beta1; Intracellular Signaling Peptides and Proteins; Kidney Glomerulus; Membrane Glycoproteins; Membrane Proteins; Microfilament Proteins; Nephrotic Syndrome; Proteins; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trans-Activators | 2002 |
Effect of aminonucleoside nephrosis on immune complex localization in autologous immune complex nephropathy in rats.
Topics: Animals; Antibody Formation; Antigen-Antibody Complex; Basement Membrane; Capillary Permeability; Disease Models, Animal; Fluorescent Antibody Technique; Immune Complex Diseases; Immunoglobulin G; Male; Microscopy, Electron; Microscopy, Fluorescence; Microvilli; Nephritis; Nephrosis; Proteinuria; Puromycin; Puromycin Aminonucleoside; Rats | 1978 |
High density lipoproteinuria in nephrotic syndrome.
Topics: Animals; Cholesterol; Disease Models, Animal; Electrophoresis, Agar Gel; Lipoproteins; Lipoproteins, HDL; Male; Nephrotic Syndrome; Phospholipids; Puromycin Aminonucleoside; Rats; Triglycerides | 1976 |
The distribution of albumin and immunoglobulin G in the glomerular capillary wall in aminonucleoside nephrosis.
Topics: Albumins; Animals; Basement Membrane; Capillaries; Disease Models, Animal; Immunoglobulin G; Kidney Glomerulus; Male; Microscopy, Electron; Nephrosis; Proteinuria; Puromycin; Puromycin Aminonucleoside; Rats | 1978 |
Experimental model of focal sclerosis. I. Relationship to protein excretion in aminonucleoside nephrosis.
Topics: Animals; Disease Models, Animal; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Injections, Intraperitoneal; Kidney Glomerulus; Male; Nephrectomy; Nephrotic Syndrome; Proteinuria; Puromycin Aminonucleoside; Rats | 1977 |
Experimental model of focal sclerosis. II. Correlation with immunopathologic changes, macromolecular kinetics, and polyanion loss.
Topics: Animals; Disease Models, Animal; Factor VIII; Fibrin; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Immunoglobulin G; Immunoglobulin M; Injections, Intraperitoneal; Kidney Glomerulus; Male; Nephrectomy; Proteinuria; Puromycin Aminonucleoside; Rats; Sialoglycoproteins | 1977 |
Unilateral renal disease in the rat. II. Glomerular mesangial uptake of colloidal carbon in unilateral aminonucleoside nephrosis and nephrotoxic serum nephritis.
Topics: Animals; Basement Membrane; Carbon; Disease Models, Animal; Immune Sera; Kidney Concentrating Ability; Kidney Glomerulus; Nephritis; Nephrosis; Perfusion; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred Lew | 1976 |
Unilateral renal disease in the rat. I. Clinical, morphologic, and glomerular mesangial functional features of the experimental model produced by renal perfusion with aminonucleoside.
Topics: Albumins; Albuminuria; Animals; Complement System Proteins; Disease Models, Animal; Fluorescent Antibody Technique; Functional Laterality; Humans; Hypercholesterolemia; Immunoglobulin G; Kidney Diseases; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Nephrectomy; Nephrotic Syndrome; Perfusion; Proteinuria; Puromycin; Puromycin Aminonucleoside; Rats; Rats, Inbred Lew; Serum Albumin; Sodium Chloride | 1975 |
Intercellular junctions in podocytes of the nephrotic glomerulus as seen with freeze-fracture.
Topics: Animals; Basement Membrane; Disease Models, Animal; Freeze Fracturing; Intercellular Junctions; Kidney Glomerulus; Nephrotic Syndrome; Puromycin Aminonucleoside; Rats | 1975 |
Renal extracellular matrix accumulation in acute puromycin aminonucleoside nephrosis in rats.
Topics: Animals; Basement Membrane; Blotting, Northern; Cell Division; Collagen; Disease Models, Animal; DNA; Extracellular Matrix; Extracellular Matrix Proteins; Female; Fibronectins; Fluorescent Antibody Technique; Gene Expression; In Situ Hybridization; Injections, Intraperitoneal; Kidney; Metalloendopeptidases; Nephrosis; Puromycin Aminonucleoside; Rats; Rats, Inbred Lew; RNA; RNA, Messenger; Thymidine; Transforming Growth Factor beta | 1992 |
Increased glomerular atrial natriuretic peptide receptor affinity in experimental nephrotic syndrome.
Topics: Animals; Atrial Natriuretic Factor; Disease Models, Animal; In Vitro Techniques; Kidney Glomerulus; Male; Nephrotic Syndrome; Protein Binding; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface | 1992 |
Mechanisms involved in the progression to glomerular sclerosis induced by systemic hypertension during mild puromycin aminonucleoside nephrosis.
Topics: Animals; Blood Pressure; Cholesterol; Disease Models, Animal; Hemodynamics; Hypertension, Renovascular; Kidney Glomerulus; Male; Nephrosis; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar; Sclerosis; Triglycerides | 1992 |
Administration of Triton WR 1339 aggravates chronic aminonucleoside nephrosis.
Topics: Animals; Cholesterol; Chronic Disease; Disease Models, Animal; Drug Synergism; Hyperlipidemias; Injections, Intravenous; Lipid Metabolism; Male; Nephrosis; Polyethylene Glycols; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Triglycerides | 1992 |
Anionic site and immunogold quantitation of heparan sulfate proteoglycans in glomerular basement membranes of puromycin aminonucleoside nephrotic rats.
Topics: Animals; Basement Membrane; Disease Models, Animal; Heparan Sulfate Proteoglycans; Heparitin Sulfate; Immunohistochemistry; Kidney Glomerulus; Male; Nephrosis; Proteoglycans; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains | 1991 |
Pathogenesis of interstitial fibrosis in chronic purine aminonucleoside nephrosis.
Topics: Albuminuria; Animals; Chronic Disease; Creatinine; Disease Models, Animal; Extracellular Matrix Proteins; Female; Fibrosis; Gene Expression; Glycoproteins; Macrophages; Metalloendopeptidases; Nephrosis; Puromycin Aminonucleoside; Rats; Rats, Inbred Lew; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta | 1991 |
Effects of YM264, a novel PAF antagonist, on puromycin aminonucleoside-induced nephropathy in the rat.
Topics: Animals; Azepines; Disease Models, Animal; Glomerulonephritis, Membranous; Hypercholesterolemia; Male; Metabolic Clearance Rate; Methylprednisolone; Piperazines; Platelet Activating Factor; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Ticlopidine; Triazoles | 1991 |
Urinary excretion of renin and angiotensinogen in nephrotic rats.
Topics: Angiotensinogen; Animals; Disease Models, Animal; Male; Nephrosis; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Renin | 1991 |
The renal functional and structural consequences of corticosteroid and angiotensin-converting enzyme inhibitor therapy in chronic puromycin aminonucleoside nephropathy.
Topics: Adrenal Cortex Hormones; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Kidney Failure, Chronic; Male; Methylprednisolone; Nephrotic Syndrome; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains | 1990 |
Cholestyramine resin ameliorates chronic aminonucleoside nephrosis.
Topics: Animals; Cholesterol; Cholestyramine Resin; Diet; Disease Models, Animal; Glomerular Filtration Rate; Hypercholesterolemia; Kidney Glomerulus; Male; Nephrosis, Lipoid; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Triglycerides | 1990 |
Mechanisms underlying transition from acute glomerular injury to late glomerular sclerosis in a rat model of nephrotic syndrome.
Topics: Animals; Blood Pressure; Disease Models, Animal; Enalapril; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Kidney Glomerulus; Male; Microcirculation; Nephrotic Syndrome; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains | 1988 |
Drug-associated glomerulopathies.
Topics: Amyloidosis; Animals; Captopril; Cyclosporins; Disease Models, Animal; Gold; Heroin Dependence; Humans; Hydrocarbons; Immune Complex Diseases; Kidney Diseases; Kidney Glomerulus; Lupus Erythematosus, Systemic; Mercury; Nephrotic Syndrome; Penicillamine; Puromycin Aminonucleoside; Serum Sickness; Solvents; Tetradecanoylphorbol Acetate | 1986 |
Membrane attack complex deposition in experimental glomerular injury.
Topics: Animals; Complement Membrane Attack Complex; Complement System Proteins; Disease Models, Animal; Fluorescent Antibody Technique; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Immune Complex Diseases; Male; Microscopy, Fluorescence; Nephrectomy; Puromycin Aminonucleoside; Rats; Rats, Inbred Lew; Rats, Inbred Strains | 1985 |
Inherited glomerular properties and their role in the expression of various forms of experimental glomerular injury.
Topics: Animals; Disease Models, Animal; Disease Susceptibility; Glomerulonephritis; Hexadimethrine Bromide; Kidney Diseases; Kidney Glomerulus; Male; Nephrosis; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Serum Sickness; Species Specificity | 1988 |
The enhancement of aminonucleoside nephrosis by the co-administration of protamine.
Topics: Animals; Complement C3; Disease Models, Animal; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Immunoenzyme Techniques; Immunoglobulins; Kidney Failure, Chronic; Kidney Glomerulus; Male; Protamines; Puromycin; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains | 1987 |
Serial micropuncture analysis of glomerular function in two rat models of glomerular sclerosis.
Topics: Animals; Blood Pressure; Blood Urea Nitrogen; Body Weight; Chronic Disease; Disease Models, Animal; Doxorubicin; Glomerular Filtration Rate; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Kidney Glomerulus; Microsurgery; Proteinuria; Punctures; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains | 1988 |
A role for oxygen free radicals in aminonucleoside nephrosis.
Topics: Allopurinol; Animals; Catalase; Depression, Chemical; Dimethyl Sulfoxide; Disease Models, Animal; Free Radicals; Male; Nephrosis; Oxygen; Proteinuria; Puromycin; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Superoxide Dismutase | 1986 |