purine has been researched along with Necrosis in 1 studies
1H-purine : The 1H-tautomer of purine.
3H-purine : The 3H-tautomer of purine.
9H-purine : The 9H-tautomer of purine.
7H-purine : The 7H-tautomer of purine.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The modeled structure of the enzyme was used for docking selective inhibitors (nucleotide analogs and the non-nucleoside inhibitor aphidicolin) in its active site in order to design new drugs for actinic keratosis and squamous cell carcinoma (SCC)." | 3.76 | Human polymerase alpha inhibitors for skin tumors. Part 2. Modeling, synthesis and influence on normal and transformed keratinocytes of new thymidine and purine derivatives. ( Dugovic, B; Höltje, HD; Höltje, M; Kleuser, B; Korting, HC; Murruzzu, C; Reissig, HU; Richartz, A; Schäfer-Korting, M; Schwanke, A; Zdrazil, B, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Höltje, M | 1 |
| Richartz, A | 1 |
| Zdrazil, B | 1 |
| Schwanke, A | 1 |
| Dugovic, B | 1 |
| Murruzzu, C | 1 |
| Reissig, HU | 1 |
| Korting, HC | 1 |
| Kleuser, B | 1 |
| Höltje, HD | 1 |
| Schäfer-Korting, M | 1 |
1 other study available for purine and Necrosis
| Article | Year |
|---|---|
Human polymerase alpha inhibitors for skin tumors. Part 2. Modeling, synthesis and influence on normal and transformed keratinocytes of new thymidine and purine derivatives.
Topics: Aphidicolin; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; DNA Polymera | 2010 |