Page last updated: 2024-10-20

purine and Leukemia, Hairy Cell

purine has been researched along with Leukemia, Hairy Cell in 4 studies

1H-purine : The 1H-tautomer of purine.
3H-purine : The 3H-tautomer of purine.
9H-purine : The 9H-tautomer of purine.
7H-purine : The 7H-tautomer of purine.

Leukemia, Hairy Cell: A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of hairy or flagellated cells in the blood and bone marrow.

Research Excerpts

ExcerptRelevanceReference
"Frontline treatment of hairy cell leukemia (HCL) with a single course of the purine nucleoside analog (PNA) produces a high rate of complete remission (CR) with prolonged durations."8.12Treatment outcomes with purine nucleoside analog alone or with rituximab for hairy cell leukemia at first relapse. ( Brander, D; Gonter-Aubin, K; Hanlon, A; Hill, BT; Hu, R; Kabel, C; Khajavian, S; Madanat, Y; Mato, A; Mian, A; Park, JH; Pinilla-Ibarz, J; Shadman, M; Stephens, DM; Tallman, M; Wei, W, 2022)
"Hairy cell leukemia (HCL) is a B-cell malignancy that in its classic form is exquisitely sensitive to single-agent purine analog therapy, but that is associated in many patients with late relapse and eventual purine analog resistance."4.88Immunoconjugates and new molecular targets in hairy cell leukemia. ( Kreitman, RJ, 2012)
"Frontline treatment of hairy cell leukemia (HCL) with a single course of the purine nucleoside analog (PNA) produces a high rate of complete remission (CR) with prolonged durations."4.12Treatment outcomes with purine nucleoside analog alone or with rituximab for hairy cell leukemia at first relapse. ( Brander, D; Gonter-Aubin, K; Hanlon, A; Hill, BT; Hu, R; Kabel, C; Khajavian, S; Madanat, Y; Mato, A; Mian, A; Park, JH; Pinilla-Ibarz, J; Shadman, M; Stephens, DM; Tallman, M; Wei, W, 2022)
"Although hairy cell leukemia (HCL) was identified in 1958 by Bouroncle and colleagues, HCL remains in 2015 a mysterious disease."2.52New insights in the management of patients with hairy cell leukemia. ( Cornet, E; Damaj, G; Troussard, X, 2015)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Hu, R1
Wei, W1
Mian, A1
Gonter-Aubin, K1
Kabel, C1
Mato, A1
Stephens, DM1
Hanlon, A1
Khajavian, S1
Shadman, M1
Brander, D1
Madanat, Y1
Park, JH1
Tallman, M1
Pinilla-Ibarz, J1
Hill, BT1
Topp, ZZ1
Saven, A1
Cornet, E1
Damaj, G1
Troussard, X1
Kreitman, RJ1

Reviews

3 reviews available for purine and Leukemia, Hairy Cell

ArticleYear
Hairy cell leukemia: a 'hair-raising' update.
    Expert review of hematology, 2014, Volume: 7, Issue:5

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bone Marrow; Drug Therapy, Combination; Humans; Leuke

2014
New insights in the management of patients with hairy cell leukemia.
    Current opinion in oncology, 2015, Volume: 27, Issue:5

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; B-Lymphocytes; Disease-Free Survival; Humans; Immunot

2015
Immunoconjugates and new molecular targets in hairy cell leukemia.
    Hematology. American Society of Hematology. Education Program, 2012, Volume: 2012

    Topics: Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; B-Lymphocytes; Bacterial Toxins; Exotoxins;

2012

Other Studies

1 other study available for purine and Leukemia, Hairy Cell

ArticleYear
Treatment outcomes with purine nucleoside analog alone or with rituximab for hairy cell leukemia at first relapse.
    European journal of haematology, 2022, Volume: 108, Issue:5

    Topics: Humans; Leukemia, Hairy Cell; Nucleosides; Purine Nucleosides; Purines; Recurrence; Rituximab; Treat

2022