purine has been researched along with Folic Acid Deficiency in 7 studies
1H-purine : The 1H-tautomer of purine.
3H-purine : The 3H-tautomer of purine.
9H-purine : The 9H-tautomer of purine.
7H-purine : The 7H-tautomer of purine.
Folic Acid Deficiency: A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined whether genetic disruption of the Shmt1 gene in mice induces NTDs in response to maternal folate and choline deficiency and whether a corresponding disruption in de novo thymidylate biosynthesis underlies NTD pathogenesis." | 3.77 | Shmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice. ( Abarinov, EV; Allen, RH; Beaudin, AE; Chu, S; Noden, DM; Perry, CA; Stabler, SP; Stover, PJ, 2011) |
| "Purine synthesis was increased when folic acid or thymidine was added to the culture medium." | 1.27 | Purine synthesis and reutilization in folate-deficient rat hepatocytes. ( Clifford, AJ; Clifford, CK; Walzem, RL, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beaudin, AE | 1 |
| Abarinov, EV | 1 |
| Noden, DM | 1 |
| Perry, CA | 1 |
| Chu, S | 1 |
| Stabler, SP | 1 |
| Allen, RH | 1 |
| Stover, PJ | 1 |
| TENTORI, L | 1 |
| VIVALDI, G | 1 |
| RICCERI, G | 1 |
| HERBERT, V | 1 |
| STREIFF, RR | 1 |
| SULLIVAN, LW | 1 |
| MCGEER, PL | 1 |
| WOODS, DD | 1 |
| Walzem, RL | 1 |
| Clifford, CK | 1 |
| Clifford, AJ | 1 |
| Chanarin, I | 1 |
| Deacon, R | 1 |
| Lumb, M | 1 |
| Muir, M | 1 |
| Perry, J | 1 |
1 review available for purine and Folic Acid Deficiency
| Article | Year |
|---|---|
Cobalamin-folate interrelations: a critical review.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Megaloblastic; Animals; Central N | 1985 |
6 other studies available for purine and Folic Acid Deficiency
| Article | Year |
|---|---|
Shmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice.
Topics: Animals; Biomarkers; Choline; Choline Deficiency; Disease Models, Animal; Folic Acid; Folic Acid Def | 2011 |
[Variations in the blood content of some metabolites of proteins and purines in experimental anemia of folic acid deficiency in the rat].
Topics: Anemia; Animals; Folic Acid; Folic Acid Deficiency; Purines; Rats | 1953 |
[Behavior of enzymes related to purine catabolism in folic acid deficiency induced by folic acid antagonists].
Topics: Folic Acid Antagonists; Folic Acid Deficiency; Liver; Oxidoreductases; Purines | 1956 |
DERANGED PURINE METABOLISM MANIFESTED BY ANINOIMIDAZOLECARBOXAMIDE EXCRETION IN MEGALOBLASTIC ANAEMIAS, HAEMOLYTIC ANAEMIA, AND LIVER DISEASE.
Topics: Anemia, Hemolytic; Anemia, Macrocytic; Anemia, Megaloblastic; Biological Assay; Blood Chemical Analy | 1964 |
THE FUNCTION OF FOLIC ACID IN CELLULAR METABOLISM.
Topics: Biochemical Phenomena; Biochemistry; Celiac Disease; Diet; Folic Acid; Folic Acid Deficiency; Glutam | 1964 |
Purine synthesis and reutilization in folate-deficient rat hepatocytes.
Topics: Animals; Body Weight; Folic Acid Deficiency; Formiminoglutamic Acid; Hypoxanthine; Hypoxanthines; Le | 1983 |