purine has been researched along with Choreoathetosis Self-Mutilation Hyperuricemia Syndrome in 18 studies
1H-purine : The 1H-tautomer of purine.
3H-purine : The 3H-tautomer of purine.
9H-purine : The 9H-tautomer of purine.
7H-purine : The 7H-tautomer of purine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lesch-Nyhan syndrome involves disorders of both purine and dopamine metabolism." | 3.67 | Assessment of purine-dopamine interactions in 6-hydroxydopamine-lesioned rats: evidence for pre- and postsynaptic influences by adenosine. ( Breese, GR; Criswell, H; Mueller, RA, 1988) |
| "The purine hypoxanthine plays important role in regulating oocyte maturation and early embryonic development." | 1.56 | Hypoxanthine phosphoribosyltransferase (HPRT)-deficiency is associated with impaired fertility in the female rat. ( Binas, B; Burdon, T; Clinton, M; Meek, S; Sturmey, R; Sutherland, L; Wei, J, 2020) |
| "Allopurinol treatment was associated with a mean 74% reduction in urinary uric acid-to-creatinine ratio." | 1.34 | Efficacy and safety of allopurinol in patients with hypoxanthine-guanine phosphoribosyltransferase deficiency. ( Prior, C; Puig, JG; Torres, RJ, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (27.78) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 3 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Vogel, M | 1 |
| Moehrle, B | 1 |
| Brown, A | 1 |
| Eiwen, K | 1 |
| Sakk, V | 1 |
| Geiger, H | 1 |
| Nguyen, KV | 1 |
| Naviaux, RK | 1 |
| Nyhan, WL | 1 |
| Meek, S | 1 |
| Sutherland, L | 1 |
| Wei, J | 1 |
| Sturmey, R | 1 |
| Binas, B | 1 |
| Clinton, M | 1 |
| Burdon, T | 1 |
| Sutcliffe, DJ | 1 |
| Dinasarapu, AR | 1 |
| Visser, JE | 1 |
| Hoed, JD | 1 |
| Seifar, F | 1 |
| Joshi, P | 1 |
| Ceballos-Picot, I | 1 |
| Sardar, T | 1 |
| Hess, EJ | 1 |
| Sun, YV | 1 |
| Wen, Z | 1 |
| Zwick, ME | 1 |
| Jinnah, HA | 1 |
| Jacomelli, G | 1 |
| Baldini, E | 1 |
| Mugnaini, C | 1 |
| Micheli, V | 1 |
| Bernardini, G | 1 |
| Santucci, A | 1 |
| Chen, BC | 1 |
| Balasubramaniam, S | 1 |
| McGown, IN | 1 |
| O'Neill, JP | 1 |
| Chng, GS | 1 |
| Keng, WT | 1 |
| Ngu, LH | 1 |
| Duley, JA | 1 |
| Torres, RJ | 2 |
| Puig, JG | 2 |
| Sebesta, I | 1 |
| Stiburková, B | 1 |
| Dvorakova, L | 1 |
| Hrebicek, M | 1 |
| Minks, J | 1 |
| Stolnaja, L | 1 |
| Vernerova, Z | 1 |
| Rychlik, I | 1 |
| Yamada, Y | 1 |
| Yamada, K | 1 |
| Nomura, N | 1 |
| Yamano, A | 1 |
| Kimura, R | 1 |
| Tomida, S | 1 |
| Naiki, M | 1 |
| Wakamatsu, N | 1 |
| Yamaoka, T | 1 |
| Morisaki, T | 1 |
| Prior, C | 1 |
| Gutensohn, W | 1 |
| MacDermot, KD | 1 |
| Allsop, J | 1 |
| Watts, RW | 1 |
| Curto, R | 1 |
| Voit, EO | 1 |
| Cascante, M | 1 |
| Krug, EC | 1 |
| Marr, JJ | 1 |
| Berens, RL | 1 |
| Wolff, JA | 1 |
| Friedmann, T | 1 |
| Criswell, H | 1 |
| Mueller, RA | 1 |
| Breese, GR | 1 |
3 reviews available for purine and Choreoathetosis Self-Mutilation Hyperuricemia Syndrome
| Article | Year |
|---|---|
[Biosynthetic pathways for purine nucleotides and uric acid].
Topics: Adenine Phosphoribosyltransferase; Adenosine Triphosphate; Allosteric Regulation; Amidophosphoribosy | 2003 |
[Animal models for abnormal purine metabolism].
Topics: Adenine Phosphoribosyltransferase; Adenosine Deaminase; AMP Deaminase; Animals; Disease Models, Anim | 2003 |
Approaches to gene therapy in disorders of purine metabolism.
Topics: Adenosine Deaminase; Animals; Bone Marrow Transplantation; DNA, Viral; Genetic Therapy; Humans; Hypo | 1988 |
15 other studies available for purine and Choreoathetosis Self-Mutilation Hyperuricemia Syndrome
| Article | Year |
|---|---|
HPRT and Purine Salvaging Are Critical for Hematopoietic Stem Cell Function.
Topics: Animals; Cell Cycle; Cell Differentiation; Cell Proliferation; Cells, Cultured; Hematopoietic Stem C | 2019 |
Lesch-Nyhan disease: I. Construction of expression vectors for hypoxanthine-guanine phosphoribosyltransferase (HGprt) enzyme and amyloid precursor protein (APP).
Topics: Amyloid beta-Protein Precursor; Epigenomics; Gene Expression Regulation; HEK293 Cells; Humans; Hypox | 2020 |
Hypoxanthine phosphoribosyltransferase (HPRT)-deficiency is associated with impaired fertility in the female rat.
Topics: Animals; Embryonic Development; Female; Fertility; Fetal Viability; Hypoxanthine; Hypoxanthine Phosp | 2020 |
Induced pluripotent stem cells from subjects with Lesch-Nyhan disease.
Topics: Adolescent; Adult; Cell Differentiation; Child; Gene Expression Profiling; Humans; Hypoxanthine Phos | 2021 |
Inhibiting PNP for the therapy of hyperuricemia in Lesch-Nyhan disease: Preliminary in vitro studies with analogues of immucillin-G.
Topics: Allopurinol; Cells, Cultured; Enzyme Inhibitors; Humans; Hyperuricemia; Hypoxanthine; Hypoxanthine P | 2019 |
Treatment of Lesch-Nyhan disease with S-adenosylmethionine: experience with five young Malaysians, including a girl.
Topics: Adolescent; Aggression; Child; Child, Preschool; Dystonia; Female; Humans; Infant; Lesch-Nyhan Syndr | 2014 |
The diagnosis of HPRT deficiency in the 21st century.
Topics: Adolescent; Allopurinol; Child, Preschool; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyh | 2008 |
Unusual presentation of Kelley-Seegmiller syndrome.
Topics: Adult; Alleles; Female; Heterozygote; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Sy | 2008 |
Molecular analysis of two enzyme genes, HPRT1 and PRPS1, causing X-linked inborn errors of purine metabolism.
Topics: DNA Mutational Analysis; Genetic Diseases, X-Linked; Genetic Predisposition to Disease; Humans; Hype | 2010 |
Efficacy and safety of allopurinol in patients with hypoxanthine-guanine phosphoribosyltransferase deficiency.
Topics: Adolescent; Adult; Allopurinol; Antimetabolites; Child; Child, Preschool; Dose-Response Relationship | 2007 |
Inherited disorders of purine metabolism--underlying molecular mechanisms.
Topics: Adenine Phosphoribosyltransferase; Adenosine Deaminase; Gout; Humans; Hypoxanthine Phosphoribosyltra | 1984 |
The rate of purine synthesis de nova in blood mononuclear cells in vitro from patients with familial hyperuricaemic nephropathy.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Erythrocytes; Female; Gout; Humans; Kidney Disease | 1984 |
Analysis of abnormalities in purine metabolism leading to gout and to neurological dysfunctions in man.
Topics: Adenylosuccinate Lyase; Aminoimidazole Carboxamide; AMP Deaminase; Gout; Humans; Hypoxanthine Phosph | 1998 |
Purine metabolism in Toxoplasma gondii.
Topics: Animals; Cell Line; Humans; Inosine; Kinetics; Lesch-Nyhan Syndrome; Purine Nucleotides; Purines; To | 1989 |
Assessment of purine-dopamine interactions in 6-hydroxydopamine-lesioned rats: evidence for pre- and postsynaptic influences by adenosine.
Topics: Adenosine; Animals; Female; Hydroxydopamines; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Sy | 1988 |