purine has been researched along with Breast Neoplasms in 9 studies
1H-purine : The 1H-tautomer of purine.
3H-purine : The 3H-tautomer of purine.
9H-purine : The 9H-tautomer of purine.
7H-purine : The 7H-tautomer of purine.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Estrogen drives breast cancer (BCa) progression by directly activating estrogen receptor α (ERα)." | 5.48 | Single-Cell Transcriptome Analysis Reveals Estrogen Signaling Coordinately Augments One-Carbon, Polyamine, and Purine Synthesis in Breast Cancer. ( Chang, S; Chen, X; Cheung, E; Cui, G; Guo, D; Hu, L; Lim, MGL; Luo, Y; Poudel, B; Robson, P; See, YX; Zhao, Z; Zhu, D, 2018) |
| "Notably, high ASS1-expressing breast cancer mice do not respond to immune checkpoint inhibitors and patients with breast cancer with high ASS1 have more metastases." | 1.56 | Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors. ( Adler, L; Ariav, Y; Brandis, A; Erez, A; Galai, S; Goldman, O; Iraqi, M; Itkin, M; Katzir, R; Keshet, R; Koehler, SE; Kuperman, Y; Kuznetsov, Y; Landesman, H; Lee, JS; Lerner, S; Lim, LQJ; Malitsky, S; Mehlman, T; Oren, R; Peled, N; Porgador, A; Rabinovich, S; Ruppin, E; Shen, TW; Stettner, N; Talsania, K; Ulitsky, I; Weiss Tishler, H; Zhao, Y, 2020) |
| "Here, we screened a subpopulation of breast cancer cells with highly metastatic capacity to the lung in mice and investigated the metabolic alternations by analyzing the metabolome and the transcriptome, which were confirmed in breast cancer cells, mouse models, and patients' tissues." | 1.56 | Nucleotide de novo synthesis increases breast cancer stemness and metastasis via cGMP-PKG-MAPK signaling pathway. ( Bai, Y; Li, X; Lv, Y; Piao, Y; Shi, Y; Wang, L; Wang, X; Wu, J; Xiang, R; Xu, G, 2020) |
| "Estrogen drives breast cancer (BCa) progression by directly activating estrogen receptor α (ERα)." | 1.48 | Single-Cell Transcriptome Analysis Reveals Estrogen Signaling Coordinately Augments One-Carbon, Polyamine, and Purine Synthesis in Breast Cancer. ( Chang, S; Chen, X; Cheung, E; Cui, G; Guo, D; Hu, L; Lim, MGL; Luo, Y; Poudel, B; Robson, P; See, YX; Zhao, Z; Zhu, D, 2018) |
| "We applied BridGE to six independent breast cancer cohorts and identified significant pathway-level interactions in five cohorts." | 1.46 | Pathway-based discovery of genetic interactions in breast cancer. ( Boone, C; Costanzo, M; Lange, CA; Myers, CL; Wang, W; Xu, ZZ, 2017) |
| "Purine analogs have been reported to be effective against chronic lymphocytic leukemia and indolent lymphomas." | 1.32 | Early reappearance of primary solid cancer in patients treated with purine analogs. ( Caracciolo, F; Fazzi, R; Galimberti, S; Petrini, M, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Keshet, R | 1 |
| Lee, JS | 1 |
| Adler, L | 1 |
| Iraqi, M | 1 |
| Ariav, Y | 1 |
| Lim, LQJ | 1 |
| Lerner, S | 1 |
| Rabinovich, S | 1 |
| Oren, R | 1 |
| Katzir, R | 1 |
| Weiss Tishler, H | 1 |
| Stettner, N | 1 |
| Goldman, O | 1 |
| Landesman, H | 1 |
| Galai, S | 1 |
| Kuperman, Y | 1 |
| Kuznetsov, Y | 1 |
| Brandis, A | 1 |
| Mehlman, T | 1 |
| Malitsky, S | 1 |
| Itkin, M | 1 |
| Koehler, SE | 1 |
| Zhao, Y | 1 |
| Talsania, K | 1 |
| Shen, TW | 1 |
| Peled, N | 1 |
| Ulitsky, I | 1 |
| Porgador, A | 1 |
| Ruppin, E | 1 |
| Erez, A | 1 |
| Lv, Y | 1 |
| Wang, X | 1 |
| Li, X | 1 |
| Xu, G | 1 |
| Bai, Y | 1 |
| Wu, J | 1 |
| Piao, Y | 1 |
| Shi, Y | 1 |
| Xiang, R | 1 |
| Wang, L | 1 |
| Wang, W | 1 |
| Xu, ZZ | 1 |
| Costanzo, M | 1 |
| Boone, C | 1 |
| Lange, CA | 1 |
| Myers, CL | 1 |
| Zhu, D | 1 |
| Zhao, Z | 1 |
| Cui, G | 1 |
| Chang, S | 1 |
| Hu, L | 1 |
| See, YX | 1 |
| Lim, MGL | 1 |
| Guo, D | 1 |
| Chen, X | 1 |
| Poudel, B | 1 |
| Robson, P | 1 |
| Luo, Y | 1 |
| Cheung, E | 1 |
| Audet-Walsh, É | 1 |
| Papadopoli, DJ | 1 |
| Gravel, SP | 1 |
| Yee, T | 1 |
| Bridon, G | 1 |
| Caron, M | 1 |
| Bourque, G | 1 |
| Giguère, V | 1 |
| St-Pierre, J | 1 |
| Núñez, MC | 1 |
| Díaz-Gavilán, M | 1 |
| Conejo-García, A | 1 |
| Cruz-López, O | 1 |
| Gallo, MA | 1 |
| Espinosa, A | 1 |
| Campos, JM | 1 |
| Fazzi, R | 1 |
| Caracciolo, F | 1 |
| Galimberti, S | 1 |
| Petrini, M | 1 |
| WHEELER, GP | 1 |
| ALEXANDER, JA | 1 |
| DODSON, AS | 1 |
| BRIGGS, SD | 1 |
| Beckers, A | 1 |
| Organe, S | 1 |
| Timmermans, L | 1 |
| Vanderhoydonc, F | 1 |
| Deboel, L | 1 |
| Derua, R | 1 |
| Waelkens, E | 1 |
| Brusselmans, K | 1 |
| Verhoeven, G | 1 |
| Swinnen, JV | 1 |
1 review available for purine and Breast Neoplasms
| Article | Year |
|---|---|
Design, synthesis and anticancer activity against the MCF-7 cell line of benzo-fused 1,4-dihetero seven- and six-membered tethered pyrimidines and purines.
Topics: Acetals; Antineoplastic Agents; Benzene Derivatives; Breast Neoplasms; Cell Line, Tumor; Cell Prolif | 2008 |
8 other studies available for purine and Breast Neoplasms
| Article | Year |
|---|---|
Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors.
Topics: Animals; Argininosuccinate Synthase; Breast Neoplasms; CD8-Positive T-Lymphocytes; Cell Line, Tumor; | 2020 |
Nucleotide de novo synthesis increases breast cancer stemness and metastasis via cGMP-PKG-MAPK signaling pathway.
Topics: Adult; Animals; Breast Neoplasms; Cell Line, Tumor; China; Cyclic GMP; Cyclic GMP-Dependent Protein | 2020 |
Pathway-based discovery of genetic interactions in breast cancer.
Topics: Breast Neoplasms; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Gonadal | 2017 |
Single-Cell Transcriptome Analysis Reveals Estrogen Signaling Coordinately Augments One-Carbon, Polyamine, and Purine Synthesis in Breast Cancer.
Topics: Breast Neoplasms; Carbon; Cell Proliferation; Cell Survival; Estrogens; Female; Folic Acid; Gene Exp | 2018 |
The PGC-1α/ERRα Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer.
Topics: AMP-Activated Protein Kinases; Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Cell Line | 2016 |
Early reappearance of primary solid cancer in patients treated with purine analogs.
Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Colic; Female; Humans; Liver Neoplasms; Mal | 2003 |
Searches for exploitable biochemical differences between normal and cancer cells. X. Catabolism of purines by regressing tumors.
Topics: Adenine; Breast Neoplasms; Castration; Diethylstilbestrol; Guanine; Humans; Hypophysectomy; Plasmacy | 1962 |
Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside.
Topics: Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Breast Neoplasms; | 2006 |