Page last updated: 2024-10-20

purine and Brain Ischemia

purine has been researched along with Brain Ischemia in 3 studies

1H-purine : The 1H-tautomer of purine.
3H-purine : The 3H-tautomer of purine.
9H-purine : The 9H-tautomer of purine.
7H-purine : The 7H-tautomer of purine.

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Using a rat model of cerebral ischemia, the ENT1 inhibitor nitrobenzylmercaptopurine ribonucleoside (NBMPR) significantly increased post-ischemic forebrain adenosine levels and significantly decreased hippocampal neuron injury relative to saline-treatment."3.73Astrocytes and neurons: different roles in regulating adenosine levels. ( Parkinson, FE; Xiong, W; Zamzow, CR, 2005)
"Transient global cerebral ischemia (tGCI) leads to selective neuronal cell death in the CA1 sub-region of the hippocampus, while the neighboring CA3 sub-region is left largely intact."1.56Metabolic basis of neuronal vulnerability to ischemia; an in vivo untargeted metabolomics approach. ( Matsumoto, Y; Niizuma, K; Rashad, S; Saigusa, D; Saito, R; Tominaga, T; Tomioka, Y; Uruno, A; Yamamoto, M; Yamazaki, T, 2020)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Rashad, S1
Saigusa, D1
Yamazaki, T1
Matsumoto, Y1
Tomioka, Y1
Saito, R1
Uruno, A1
Niizuma, K1
Yamamoto, M1
Tominaga, T1
Parkinson, FE1
Xiong, W1
Zamzow, CR1
Siniscalchi, A1
Rodi, D1
Gessi, S1
Campi, F1
Borea, PA1

Other Studies

3 other studies available for purine and Brain Ischemia

ArticleYear
Metabolic basis of neuronal vulnerability to ischemia; an in vivo untargeted metabolomics approach.
    Scientific reports, 2020, 04-16, Volume: 10, Issue:1

    Topics: Animals; Apoptosis; Brain Ischemia; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Chromatography

2020
Astrocytes and neurons: different roles in regulating adenosine levels.
    Neurological research, 2005, Volume: 27, Issue:2

    Topics: Adenosine; Affinity Labels; Animals; Astrocytes; Brain Ischemia; Cells, Cultured; Deoxyglucose; Dipy

2005
Early changes in adenosine A1 receptors in cerebral cortex slices submitted to in vitro ischemia.
    Neurochemistry international, 1999, Volume: 34, Issue:6

    Topics: Adenosine; Animals; Brain Ischemia; Cerebral Cortex; Male; Purines; Rats; Rats, Sprague-Dawley; Rece

1999