purine has been researched along with Brain Ischemia in 3 studies
1H-purine : The 1H-tautomer of purine.
3H-purine : The 3H-tautomer of purine.
9H-purine : The 9H-tautomer of purine.
7H-purine : The 7H-tautomer of purine.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using a rat model of cerebral ischemia, the ENT1 inhibitor nitrobenzylmercaptopurine ribonucleoside (NBMPR) significantly increased post-ischemic forebrain adenosine levels and significantly decreased hippocampal neuron injury relative to saline-treatment." | 3.73 | Astrocytes and neurons: different roles in regulating adenosine levels. ( Parkinson, FE; Xiong, W; Zamzow, CR, 2005) |
| "Transient global cerebral ischemia (tGCI) leads to selective neuronal cell death in the CA1 sub-region of the hippocampus, while the neighboring CA3 sub-region is left largely intact." | 1.56 | Metabolic basis of neuronal vulnerability to ischemia; an in vivo untargeted metabolomics approach. ( Matsumoto, Y; Niizuma, K; Rashad, S; Saigusa, D; Saito, R; Tominaga, T; Tomioka, Y; Uruno, A; Yamamoto, M; Yamazaki, T, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Rashad, S | 1 |
| Saigusa, D | 1 |
| Yamazaki, T | 1 |
| Matsumoto, Y | 1 |
| Tomioka, Y | 1 |
| Saito, R | 1 |
| Uruno, A | 1 |
| Niizuma, K | 1 |
| Yamamoto, M | 1 |
| Tominaga, T | 1 |
| Parkinson, FE | 1 |
| Xiong, W | 1 |
| Zamzow, CR | 1 |
| Siniscalchi, A | 1 |
| Rodi, D | 1 |
| Gessi, S | 1 |
| Campi, F | 1 |
| Borea, PA | 1 |
3 other studies available for purine and Brain Ischemia
| Article | Year |
|---|---|
Metabolic basis of neuronal vulnerability to ischemia; an in vivo untargeted metabolomics approach.
Topics: Animals; Apoptosis; Brain Ischemia; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Chromatography | 2020 |
Astrocytes and neurons: different roles in regulating adenosine levels.
Topics: Adenosine; Affinity Labels; Animals; Astrocytes; Brain Ischemia; Cells, Cultured; Deoxyglucose; Dipy | 2005 |
Early changes in adenosine A1 receptors in cerebral cortex slices submitted to in vitro ischemia.
Topics: Adenosine; Animals; Brain Ischemia; Cerebral Cortex; Male; Purines; Rats; Rats, Sprague-Dawley; Rece | 1999 |