purine has been researched along with Alzheimer Disease in 4 studies
1H-purine : The 1H-tautomer of purine.
3H-purine : The 3H-tautomer of purine.
9H-purine : The 9H-tautomer of purine.
7H-purine : The 7H-tautomer of purine.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Due to the complex nature of Alzheimer's disease, there is a renewed search for pleiotropic agents." | 1.42 | Purine homo-N-nucleoside+coumarin hybrids as pleiotropic agents for the potential treatment of Alzheimer's disease. ( Hadjipavlou-Litina, DJ; Kallitsakis, MG; Litinas, KE; Marco-Contelles, J; Soriano, E; Yañez, M, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McFarland, NR | 1 |
| Burdett, T | 1 |
| Desjardins, CA | 1 |
| Frosch, MP | 1 |
| Schwarzschild, MA | 1 |
| Ansoleaga, B | 1 |
| Jové, M | 1 |
| Schlüter, A | 1 |
| Garcia-Esparcia, P | 1 |
| Moreno, J | 1 |
| Pujol, A | 1 |
| Pamplona, R | 1 |
| Portero-Otín, M | 1 |
| Ferrer, I | 1 |
| Kallitsakis, MG | 1 |
| Yañez, M | 1 |
| Soriano, E | 1 |
| Marco-Contelles, J | 1 |
| Hadjipavlou-Litina, DJ | 1 |
| Litinas, KE | 1 |
| Heshmati, Y | 1 |
| Mirabzadeh, A | 1 |
| Feizzade, G | 1 |
| Gilanipour, M | 1 |
| Etminan, MR | 1 |
| Khoram Khorshid, HR | 1 |
| Kamali, K | 1 |
| Fakhri, M | 1 |
| Moghimi, N | 1 |
| Najmabadi, H | 1 |
| Ohadi, M | 1 |
4 other studies available for purine and Alzheimer Disease
| Article | Year |
|---|---|
Postmortem brain levels of urate and precursors in Parkinson's disease and related disorders.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Brain; Case-Control Studies; Femal | 2013 |
Deregulation of purine metabolism in Alzheimer's disease.
Topics: Adenosine Triphosphatases; Adenylate Kinase; Aged; Aged, 80 and over; Alzheimer Disease; Chromatogra | 2015 |
Purine homo-N-nucleoside+coumarin hybrids as pleiotropic agents for the potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Coumarins; Glycine max; Humans; Hypolipidemic Agents; Lipoxygenase; Lipoxygenase | 2015 |
A novel polymorphic purine complex at the 1.5 kb upstream region of the human caveolin-1 gene and risk of Alzheimer's disease; extra-short alleles and accumulated allele homozygosity.
Topics: Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Base Sequence; Caveolin 1; DNA Mutational Analy | 2009 |