punicalagin has been researched along with Herpes-Simplex* in 1 studies
1 other study(ies) available for punicalagin and Herpes-Simplex
Article | Year |
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In vitro permeation and biological activity of punicalagin and zinc (II) across skin and mucous membranes prone to Herpes simplex virus infection.
Coadministration of pomegranate rind extract (PRE) and zinc (II) ions has recently been reported as a potential new topical treatment for Herpes simplex virus (HSV) infections. In the current work we examined the in vitro topical delivery of punicalagin (major phytochemical of PRE) and zinc from hydrogels across epithelial membranes that can become infected with HSV. Porcine epidermal, buccal and vaginal mucous membranes were excised and mounted in Franz diffusion cells and dosed with a simple hydrogel containing PRE and zinc sulphate (ZnSO Topics: Animals; Anti-Inflammatory Agents; Antiviral Agents; Chlorocebus aethiops; Cyclooxygenase 2; Female; Herpes Simplex; Herpesvirus 1, Human; Hydrogels; Hydrolyzable Tannins; Hypromellose Derivatives; In Vitro Techniques; Mucous Membrane; Skin; Swine; Vero Cells; Zinc Sulfate | 2017 |