pteridines has been researched along with Thyroid Carcinoma, Anaplastic in 2 studies
Thyroid Carcinoma, Anaplastic: An aggressive THYROID GLAND malignancy which generally occurs in IODINE-deficient areas in people with previous thyroid pathology such as GOITER. It is associated with CELL DEDIFFERENTIATION of THYROID CARCINOMA (e.g., FOLLICULAR THYROID CARCINOMA; PAPILLARY THYROID CANCER). Typical initial presentation is a rapidly growing neck mass which upon metastasis is associated with DYSPHAGIA; NECK PAIN; bone pain; DYSPNEA; and NEUROLOGIC DEFICITS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Anaplastic thyroid cancer (ATC) is among the most lethal malignancies." | 1.48 | PI3K blockage synergizes with PLK1 inhibition preventing endoreduplication and enhancing apoptosis in anaplastic thyroid cancer. ( De Martino, D; Di Cristofano, A; Orlacchio, A; Ranieri, M; Yilmaz, E; Zhao, K, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, SF | 1 |
| Yeh, CN | 1 |
| Huang, YT | 1 |
| Chou, TC | 1 |
| Wong, RJ | 1 |
| De Martino, D | 1 |
| Yilmaz, E | 1 |
| Orlacchio, A | 1 |
| Ranieri, M | 1 |
| Zhao, K | 1 |
| Di Cristofano, A | 1 |
2 other studies available for pteridines and Thyroid Carcinoma, Anaplastic
| Article | Year |
|---|---|
Therapeutic inhibition of polo-like kinases in anaplastic thyroid cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Huma | 2021 |
PI3K blockage synergizes with PLK1 inhibition preventing endoreduplication and enhancing apoptosis in anaplastic thyroid cancer.
Topics: Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle Prote | 2018 |