pteridines has been researched along with Retinoblastoma in 3 studies
Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Retinoblastoma is the most common intraocular tumor in children resulting from genetic alterations and transformation of mature retinal cells." | 5.43 | Evaluation of SD-208, a TGF-β-RI Kinase Inhibitor, as an Anticancer Agent in Retinoblastoma. ( Abed Khojasteh, H; Akbari, A; Bolhassani, M; Fadakar, P; Ghassemi, F; Heidari, M; Mobini, GR; Mohebi, M, 2016) |
| "Retinoblastoma is the most common malignant cancer of the eye in children." | 1.46 | Pharmaceutically inhibiting polo-like kinase 1 exerts a broad anti-tumour activity in retinoblastoma cell lines. ( Althoff, K; Dreesmann, S; Eggert, A; Schramm, A; Schulte, JH; Schwermer, M; Steenpass, L; Temming, P, 2017) |
| "Retinoblastoma is the most common intraocular tumor in children resulting from genetic alterations and transformation of mature retinal cells." | 1.43 | Evaluation of SD-208, a TGF-β-RI Kinase Inhibitor, as an Anticancer Agent in Retinoblastoma. ( Abed Khojasteh, H; Akbari, A; Bolhassani, M; Fadakar, P; Ghassemi, F; Heidari, M; Mobini, GR; Mohebi, M, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yunoki, T | 1 |
| Tabuchi, Y | 1 |
| Hayashi, A | 1 |
| Kondo, T | 1 |
| Fadakar, P | 1 |
| Akbari, A | 1 |
| Ghassemi, F | 1 |
| Mobini, GR | 1 |
| Mohebi, M | 1 |
| Bolhassani, M | 1 |
| Abed Khojasteh, H | 1 |
| Heidari, M | 1 |
| Schwermer, M | 1 |
| Dreesmann, S | 1 |
| Eggert, A | 1 |
| Althoff, K | 1 |
| Steenpass, L | 1 |
| Schramm, A | 1 |
| Schulte, JH | 1 |
| Temming, P | 1 |
3 other studies available for pteridines and Retinoblastoma
| Article | Year |
|---|---|
Inhibition of polo-like kinase 1 promotes hyperthermia sensitivity via inactivation of heat shock transcription factor 1 in human retinoblastoma cells.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; C | 2013 |
Evaluation of SD-208, a TGF-β-RI Kinase Inhibitor, as an Anticancer Agent in Retinoblastoma.
Topics: Cell Line, Tumor; Cell Proliferation; Child; Gene Expression Regulation, Neoplastic; Humans; MicroRN | 2016 |
Pharmaceutically inhibiting polo-like kinase 1 exerts a broad anti-tumour activity in retinoblastoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Blotting, Western; CDC2 Protein Kinase; Cell Cycle | 2017 |