pteridines has been researched along with Pulmonary Fibrosis in 3 studies
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pulmonary fibrosis is characterized by chronic scar formation and deposition of extracellular matrix, resulting in impaired lung function and respiratory failure." | 1.33 | Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor. ( Bonniaud, P; Chakravarty, S; Damm, D; Dugar, S; Gauldie, J; Higgins, L; Kapoun, AM; Kolb, M; Margetts, PJ; Murphy, A; Protter, AA; Schroeder, JA, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, R | 1 |
| Šumová, B | 1 |
| Cordazzo, C | 1 |
| Mallano, T | 1 |
| Zhang, Y | 1 |
| Wohlfahrt, T | 1 |
| Dees, C | 1 |
| Ramming, A | 1 |
| Krasowska, D | 1 |
| Michalska-Jakubus, M | 1 |
| Distler, O | 1 |
| Schett, G | 1 |
| Šenolt, L | 1 |
| Distler, JH | 1 |
| Bonniaud, P | 1 |
| Margetts, PJ | 1 |
| Kolb, M | 1 |
| Schroeder, JA | 1 |
| Kapoun, AM | 2 |
| Damm, D | 2 |
| Murphy, A | 2 |
| Chakravarty, S | 2 |
| Dugar, S | 2 |
| Higgins, L | 1 |
| Protter, AA | 2 |
| Gauldie, J | 1 |
| Gaspar, NJ | 1 |
| Wang, Y | 1 |
| Liu, YW | 1 |
| O'young, G | 1 |
| Quon, D | 1 |
| Lam, A | 1 |
| Munson, K | 1 |
| Tran, TT | 1 |
| Ma, JY | 1 |
| Wen, FQ | 1 |
| Liu, X | 1 |
| Rennard, SI | 1 |
| Higgins, LS | 1 |
3 other studies available for pteridines and Pulmonary Fibrosis
| Article | Year |
|---|---|
The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc.
Topics: Adult; Aged; Anilides; Animals; Cells, Cultured; Collagen Type I; Connective Tissue Growth Factor; F | 2017 |
Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor.
Topics: Activin Receptors, Type I; Administration, Oral; Animals; Cells, Cultured; Down-Regulation; Female; | 2005 |
Transforming growth factor-beta receptor type 1 (TGFbetaRI) kinase activity but not p38 activation is required for TGFbetaRI-induced myofibroblast differentiation and profibrotic gene expression.
Topics: Activin Receptors, Type I; Cell Differentiation; Cells, Cultured; Collagen; Connective Tissue Growth | 2006 |