pteridines has been researched along with Parkinson Disease in 13 studies
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (69.23) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ichinose, H | 1 |
| Inoue, KI | 1 |
| Arakawa, S | 1 |
| Watanabe, Y | 1 |
| Kurosaki, H | 1 |
| Koshiba, S | 1 |
| Hustad, E | 1 |
| Takada, M | 1 |
| Aasly, JO | 1 |
| Nagatsu, T | 5 |
| Yamaguchi, T | 3 |
| Kato, T | 1 |
| Sugimoto, T | 3 |
| Matsuura, S | 3 |
| Akino, M | 2 |
| Nagatsu, I | 2 |
| Iizuka, R | 3 |
| Narabayashi, H | 3 |
| Rahman, MK | 1 |
| Trocewicz, J | 1 |
| Oka, K | 1 |
| Hirata, Y | 1 |
| Kondo, T | 2 |
| LeWitt, PA | 1 |
| Miller, LP | 1 |
| Newman, RP | 1 |
| Burns, RS | 1 |
| Insel, T | 1 |
| Levine, RA | 2 |
| Lovenberg, W | 3 |
| Calne, DB | 2 |
| Curtius, HC | 1 |
| Niederwieser, A | 1 |
| Levine, R | 2 |
| Müldner, H | 1 |
| Williams, A | 1 |
| Ballenger, J | 1 |
| Calne, D | 1 |
| Nakamura, K | 1 |
| Wright, DA | 1 |
| Wiatr, T | 1 |
| Kowlessur, D | 1 |
| Milstien, S | 1 |
| Lei, XG | 1 |
| Kang, UJ | 1 |
| Gramsbergen, JB | 1 |
| Sandberg, M | 1 |
| Møller Dall, A | 1 |
| Kornblit, B | 1 |
| Zimmer, J | 1 |
| Robinson, DS | 1 |
| Ebert, M | 1 |
| Williams, AC | 1 |
| Sawada, M | 1 |
| Horikoshi, T | 1 |
| Masada, M | 1 |
| Baker, H | 1 |
| Frank, O | 1 |
| Bacchi, CJ | 1 |
| Hunter, SH | 1 |
1 review available for pteridines and Parkinson Disease
| Article | Year |
|---|---|
Tyrosine hydroxylase: human isoforms, structure and regulation in physiology and pathology.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cricetinae; Gene Expression Regulation, Enzymologic; Hu | 1995 |
12 other studies available for pteridines and Parkinson Disease
| Article | Year |
|---|---|
Alterations in the reduced pteridine contents in the cerebrospinal fluids of LRRK2 mutation carriers and patients with Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Animals; Biomarkers; Female; Heterozygote; Humans; Leucine-Rich Repe | 2018 |
Biopterin in human brain and urine from controls and parkinsonian patients: application of a new radioimmunoassay.
Topics: Aged; Biopterins; Brain Chemistry; Humans; Middle Aged; Parkinson Disease; Postmortem Changes; Pteri | 1981 |
Catecholamine-related enzymes and the biopterin cofactor in Parkinson's disease and related extrapyramidal diseases.
Topics: Adult; Aged; Aromatic-L-Amino-Acid Decarboxylases; Basal Ganglia Diseases; Biopterins; Brain; Dopa D | 1984 |
Tyrosine hydroxylase cofactor (tetrahydrobiopterin) in parkinsonism.
Topics: Adult; Age Factors; Aged; Animals; Antiparkinson Agents; Biopterins; Brain Chemistry; Drug Evaluatio | 1984 |
Therapeutic efficacy of tetrahydrobiopterin in Parkinson's disease.
Topics: Aged; Antidepressive Agents; Antiparkinson Agents; Biopterins; Brain; Depressive Disorder; Drug Eval | 1984 |
Effects of tyrosine administration on serum biopterin in normal controls and patients with Parkinson's disease.
Topics: Administration, Oral; Adrenal Glands; Alanine; Animals; Biopterins; Corpus Striatum; Humans; Injecti | 1983 |
Aging and CSF hydroxylase cofactor.
Topics: Adult; Aged; Aging; Biopterins; Humans; Middle Aged; Parkinson Disease; Pteridines | 1980 |
Preferential resistance of dopaminergic neurons to the toxicity of glutathione depletion is independent of cellular glutathione peroxidase and is mediated by tetrahydrobiopterin.
Topics: Animals; Antioxidants; Biopterins; Buthionine Sulfoximine; Cell Survival; Dopamine; Enzyme Inhibitor | 2000 |
Glutathione depletion in nigrostriatal slice cultures: GABA loss, dopamine resistance and protection by the tetrahydrobiopterin precursor sepiapterin.
Topics: Animals; Animals, Newborn; Biopterins; Buthionine Sulfoximine; Coculture Techniques; Dopamine; Enzym | 2002 |
Hydroxylase cofactor activity in cerebrospinal fluid of normal subjects and patients with Parkinson's disease.
Topics: Biopterins; Homovanillic Acid; Humans; Methods; Parkinson Disease; Pteridines | 1979 |
A sensitive assay of GTP cyclohydrolase I activity in rat and human tissues using radioimmunoassay of neopterin.
Topics: Aminohydrolases; Animals; Biopterins; Brain; Caudate Nucleus; GTP Cyclohydrolase; Humans; Male; Neop | 1986 |
Biopterin content of human and rat fluids and tissues determined protozoologically.
Topics: Alcoholism; Animals; Biological Assay; Brain Chemistry; Erythrocytes; Eukaryota; Gout; Humans; Liver | 1974 |