pteridines has been researched along with Brain Neoplasms in 11 studies
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
Excerpt | Relevance | Reference |
---|---|---|
"Glioblastoma (GBM) is the deadliest primary brain tumor that is highly resistant to current treatments." | 1.56 | Dual PLK1 and STAT3 inhibition promotes glioblastoma cells apoptosis through MYC. ( Chen, G; Deng, Z; Feng, M; Feng, Z; Li, X; Li, Y; Pan, T; Tao, Z; Wang, H; Yin, H; Zhao, G; Zhou, Y, 2020) |
"Medulloblastoma is the most common malignant brain tumor in children." | 1.39 | Personalizing the treatment of pediatric medulloblastoma: Polo-like kinase 1 as a molecular target in high-risk children. ( Berns, R; Bouffet, E; Dunham, C; Dunn, SE; Foster, C; Fotovati, A; Hawkins, C; Hukin, J; Lee, C; Manoranjan, B; Narendran, A; Northcott, P; O'Halloran, K; Pambid, MR; Ramaswamy, V; Rassekh, R; Singh, SK; Singhal, A; Taylor, MD; Triscott, J; Venugopal, C; Yip, S, 2013) |
"Gliomas are the most devastating of primary adult malignant brain tumors." | 1.38 | Glioma-propagating cells as an in vitro screening platform: PLK1 as a case study. ( Ang, BT; Brooks, HB; Campbell, RM; Chong, YK; Foong, CS; Sandanaraj, E; Tang, C, 2012) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 8 (72.73) | 24.3611 |
2020's | 3 (27.27) | 2.80 |
Authors | Studies |
---|---|
Li, X | 2 |
Tao, Z | 2 |
Wang, H | 2 |
Deng, Z | 2 |
Zhou, Y | 2 |
Du, Z | 1 |
Feng, M | 1 |
Zhao, G | 1 |
Yin, H | 1 |
Pan, T | 1 |
Chen, G | 1 |
Feng, Z | 1 |
Li, Y | 1 |
Zhu, Z | 1 |
Wang, J | 1 |
Tan, J | 1 |
Yao, YL | 1 |
He, ZC | 1 |
Xie, XQ | 1 |
Yan, ZX | 1 |
Fu, WJ | 1 |
Liu, Q | 1 |
Wang, YX | 1 |
Luo, T | 1 |
Bian, XW | 1 |
Schmidt, C | 1 |
Schubert, NA | 1 |
Brabetz, S | 1 |
Mack, N | 1 |
Schwalm, B | 1 |
Chan, JA | 1 |
Selt, F | 1 |
Herold-Mende, C | 1 |
Witt, O | 1 |
Milde, T | 1 |
Pfister, SM | 1 |
Korshunov, A | 1 |
Kool, M | 1 |
Triscott, J | 2 |
Lee, C | 2 |
Foster, C | 1 |
Manoranjan, B | 1 |
Pambid, MR | 1 |
Berns, R | 1 |
Fotovati, A | 2 |
Venugopal, C | 2 |
O'Halloran, K | 1 |
Narendran, A | 2 |
Hawkins, C | 1 |
Ramaswamy, V | 1 |
Bouffet, E | 1 |
Taylor, MD | 1 |
Singhal, A | 2 |
Hukin, J | 1 |
Rassekh, R | 1 |
Yip, S | 2 |
Northcott, P | 1 |
Singh, SK | 2 |
Dunham, C | 2 |
Dunn, SE | 2 |
Danovi, D | 1 |
Folarin, A | 1 |
Gogolok, S | 1 |
Ender, C | 1 |
Elbatsh, AM | 1 |
Engström, PG | 1 |
Stricker, SH | 1 |
Gagrica, S | 1 |
Georgian, A | 1 |
Yu, D | 1 |
U, KP | 1 |
Harvey, KJ | 1 |
Ferretti, P | 1 |
Paddison, PJ | 1 |
Preston, JE | 1 |
Abbott, NJ | 1 |
Bertone, P | 1 |
Smith, A | 1 |
Pollard, SM | 1 |
Amani, V | 1 |
Prince, EW | 1 |
Alimova, I | 1 |
Balakrishnan, I | 1 |
Birks, D | 1 |
Donson, AM | 1 |
Harris, P | 1 |
Levy, JM | 1 |
Handler, M | 1 |
Foreman, NK | 1 |
Venkataraman, S | 1 |
Vibhakar, R | 1 |
Xiao, D | 1 |
Yue, M | 1 |
Su, H | 1 |
Ren, P | 1 |
Jiang, J | 1 |
Li, F | 1 |
Hu, Y | 1 |
Du, H | 1 |
Liu, H | 1 |
Qing, G | 1 |
Grinshtein, N | 1 |
Datti, A | 1 |
Fujitani, M | 1 |
Uehling, D | 1 |
Prakesch, M | 1 |
Isaac, M | 1 |
Irwin, MS | 1 |
Wrana, JL | 1 |
Al-Awar, R | 1 |
Kaplan, DR | 1 |
Chen, J | 1 |
Kerr, JM | 1 |
Verreault, M | 1 |
Wakimoto, H | 1 |
Jones, C | 1 |
Jayanthan, A | 1 |
Foong, CS | 1 |
Sandanaraj, E | 1 |
Brooks, HB | 1 |
Campbell, RM | 1 |
Ang, BT | 1 |
Chong, YK | 1 |
Tang, C | 1 |
11 other studies available for pteridines and Brain Neoplasms
Article | Year |
---|---|
Dual inhibition of Src and PLK1 regulate stemness and induce apoptosis through Notch1-SOX2 signaling in EGFRvIII positive glioma stem cells (GSCs).
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzodioxoles; Brain Neoplasms; Cell Cycle Proteins; Cell | 2020 |
Dual PLK1 and STAT3 inhibition promotes glioblastoma cells apoptosis through MYC.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Carcinogenesis; Cell Cycle Proteins; Cel | 2020 |
Calcyphosine promotes the proliferation of glioma cells and serves as a potential therapeutic target.
Topics: Adult; Aged; Animals; Apoptosis; Brain Neoplasms; Calcium-Binding Proteins; Cell Cycle; Cell Prolife | 2021 |
Preclinical drug screen reveals topotecan, actinomycin D, and volasertib as potential new therapeutic candidates for ETMR brain tumor patients.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Proliferation; Ch | 2017 |
Personalizing the treatment of pediatric medulloblastoma: Polo-like kinase 1 as a molecular target in high-risk children.
Topics: Adolescent; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Cycle Proteins; Child; Child, Pres | 2013 |
A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1.
Topics: Animals; Benzimidazoles; Blood-Brain Barrier; Blotting, Western; Brain Neoplasms; Cell Cycle Checkpo | 2013 |
Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma.
Topics: Brain Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Damag | 2016 |
Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle | 2016 |
Small molecule kinase inhibitor screen identifies polo-like kinase 1 as a target for neuroblastoma tumor-initiating cells.
Topics: Algorithms; Animals; Brain Neoplasms; Cell Cycle Proteins; Cells, Cultured; High-Throughput Screenin | 2011 |
Polo-like kinase 1 inhibition kills glioblastoma multiforme brain tumor cells in part through loss of SOX2 and delays tumor progression in mice.
Topics: Animals; Apoptosis; Brain Neoplasms; Cell Cycle Proteins; Cell Growth Processes; Cell Line, Tumor; D | 2012 |
Glioma-propagating cells as an in vitro screening platform: PLK1 as a case study.
Topics: Animals; Brain Neoplasms; Cell Cycle Proteins; Cell Proliferation; Cell Survival; Computational Biol | 2012 |