pteridines has been researched along with Benign Neoplasms, Brain in 11 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glioblastoma (GBM) is the deadliest primary brain tumor that is highly resistant to current treatments." | 1.56 | Dual PLK1 and STAT3 inhibition promotes glioblastoma cells apoptosis through MYC. ( Chen, G; Deng, Z; Feng, M; Feng, Z; Li, X; Li, Y; Pan, T; Tao, Z; Wang, H; Yin, H; Zhao, G; Zhou, Y, 2020) |
| "Medulloblastoma is the most common malignant brain tumor in children." | 1.39 | Personalizing the treatment of pediatric medulloblastoma: Polo-like kinase 1 as a molecular target in high-risk children. ( Berns, R; Bouffet, E; Dunham, C; Dunn, SE; Foster, C; Fotovati, A; Hawkins, C; Hukin, J; Lee, C; Manoranjan, B; Narendran, A; Northcott, P; O'Halloran, K; Pambid, MR; Ramaswamy, V; Rassekh, R; Singh, SK; Singhal, A; Taylor, MD; Triscott, J; Venugopal, C; Yip, S, 2013) |
| "Gliomas are the most devastating of primary adult malignant brain tumors." | 1.38 | Glioma-propagating cells as an in vitro screening platform: PLK1 as a case study. ( Ang, BT; Brooks, HB; Campbell, RM; Chong, YK; Foong, CS; Sandanaraj, E; Tang, C, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (72.73) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Li, X | 2 |
| Tao, Z | 2 |
| Wang, H | 2 |
| Deng, Z | 2 |
| Zhou, Y | 2 |
| Du, Z | 1 |
| Feng, M | 1 |
| Zhao, G | 1 |
| Yin, H | 1 |
| Pan, T | 1 |
| Chen, G | 1 |
| Feng, Z | 1 |
| Li, Y | 1 |
| Zhu, Z | 1 |
| Wang, J | 1 |
| Tan, J | 1 |
| Yao, YL | 1 |
| He, ZC | 1 |
| Xie, XQ | 1 |
| Yan, ZX | 1 |
| Fu, WJ | 1 |
| Liu, Q | 1 |
| Wang, YX | 1 |
| Luo, T | 1 |
| Bian, XW | 1 |
| Schmidt, C | 1 |
| Schubert, NA | 1 |
| Brabetz, S | 1 |
| Mack, N | 1 |
| Schwalm, B | 1 |
| Chan, JA | 1 |
| Selt, F | 1 |
| Herold-Mende, C | 1 |
| Witt, O | 1 |
| Milde, T | 1 |
| Pfister, SM | 1 |
| Korshunov, A | 1 |
| Kool, M | 1 |
| Triscott, J | 2 |
| Lee, C | 2 |
| Foster, C | 1 |
| Manoranjan, B | 1 |
| Pambid, MR | 1 |
| Berns, R | 1 |
| Fotovati, A | 2 |
| Venugopal, C | 2 |
| O'Halloran, K | 1 |
| Narendran, A | 2 |
| Hawkins, C | 1 |
| Ramaswamy, V | 1 |
| Bouffet, E | 1 |
| Taylor, MD | 1 |
| Singhal, A | 2 |
| Hukin, J | 1 |
| Rassekh, R | 1 |
| Yip, S | 2 |
| Northcott, P | 1 |
| Singh, SK | 2 |
| Dunham, C | 2 |
| Dunn, SE | 2 |
| Danovi, D | 1 |
| Folarin, A | 1 |
| Gogolok, S | 1 |
| Ender, C | 1 |
| Elbatsh, AM | 1 |
| Engström, PG | 1 |
| Stricker, SH | 1 |
| Gagrica, S | 1 |
| Georgian, A | 1 |
| Yu, D | 1 |
| U, KP | 1 |
| Harvey, KJ | 1 |
| Ferretti, P | 1 |
| Paddison, PJ | 1 |
| Preston, JE | 1 |
| Abbott, NJ | 1 |
| Bertone, P | 1 |
| Smith, A | 1 |
| Pollard, SM | 1 |
| Amani, V | 1 |
| Prince, EW | 1 |
| Alimova, I | 1 |
| Balakrishnan, I | 1 |
| Birks, D | 1 |
| Donson, AM | 1 |
| Harris, P | 1 |
| Levy, JM | 1 |
| Handler, M | 1 |
| Foreman, NK | 1 |
| Venkataraman, S | 1 |
| Vibhakar, R | 1 |
| Xiao, D | 1 |
| Yue, M | 1 |
| Su, H | 1 |
| Ren, P | 1 |
| Jiang, J | 1 |
| Li, F | 1 |
| Hu, Y | 1 |
| Du, H | 1 |
| Liu, H | 1 |
| Qing, G | 1 |
| Grinshtein, N | 1 |
| Datti, A | 1 |
| Fujitani, M | 1 |
| Uehling, D | 1 |
| Prakesch, M | 1 |
| Isaac, M | 1 |
| Irwin, MS | 1 |
| Wrana, JL | 1 |
| Al-Awar, R | 1 |
| Kaplan, DR | 1 |
| Chen, J | 1 |
| Kerr, JM | 1 |
| Verreault, M | 1 |
| Wakimoto, H | 1 |
| Jones, C | 1 |
| Jayanthan, A | 1 |
| Foong, CS | 1 |
| Sandanaraj, E | 1 |
| Brooks, HB | 1 |
| Campbell, RM | 1 |
| Ang, BT | 1 |
| Chong, YK | 1 |
| Tang, C | 1 |
11 other studies available for pteridines and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Dual inhibition of Src and PLK1 regulate stemness and induce apoptosis through Notch1-SOX2 signaling in EGFRvIII positive glioma stem cells (GSCs).
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzodioxoles; Brain Neoplasms; Cell Cycle Proteins; Cell | 2020 |
Dual PLK1 and STAT3 inhibition promotes glioblastoma cells apoptosis through MYC.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Carcinogenesis; Cell Cycle Proteins; Cel | 2020 |
Calcyphosine promotes the proliferation of glioma cells and serves as a potential therapeutic target.
Topics: Adult; Aged; Animals; Apoptosis; Brain Neoplasms; Calcium-Binding Proteins; Cell Cycle; Cell Prolife | 2021 |
Preclinical drug screen reveals topotecan, actinomycin D, and volasertib as potential new therapeutic candidates for ETMR brain tumor patients.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Proliferation; Ch | 2017 |
Personalizing the treatment of pediatric medulloblastoma: Polo-like kinase 1 as a molecular target in high-risk children.
Topics: Adolescent; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Cycle Proteins; Child; Child, Pres | 2013 |
A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1.
Topics: Animals; Benzimidazoles; Blood-Brain Barrier; Blotting, Western; Brain Neoplasms; Cell Cycle Checkpo | 2013 |
Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma.
Topics: Brain Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Damag | 2016 |
Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle | 2016 |
Small molecule kinase inhibitor screen identifies polo-like kinase 1 as a target for neuroblastoma tumor-initiating cells.
Topics: Algorithms; Animals; Brain Neoplasms; Cell Cycle Proteins; Cells, Cultured; High-Throughput Screenin | 2011 |
Polo-like kinase 1 inhibition kills glioblastoma multiforme brain tumor cells in part through loss of SOX2 and delays tumor progression in mice.
Topics: Animals; Apoptosis; Brain Neoplasms; Cell Cycle Proteins; Cell Growth Processes; Cell Line, Tumor; D | 2012 |
Glioma-propagating cells as an in vitro screening platform: PLK1 as a case study.
Topics: Animals; Brain Neoplasms; Cell Cycle Proteins; Cell Proliferation; Cell Survival; Computational Biol | 2012 |