pteridines has been researched along with Astrocytoma, Grade IV in 6 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glioblastoma (GBM) is the deadliest primary brain tumor that is highly resistant to current treatments." | 1.56 | Dual PLK1 and STAT3 inhibition promotes glioblastoma cells apoptosis through MYC. ( Chen, G; Deng, Z; Feng, M; Feng, Z; Li, X; Li, Y; Pan, T; Tao, Z; Wang, H; Yin, H; Zhao, G; Zhou, Y, 2020) |
| "Treatment with BI 2536 caused mitotic arrest after 24 hours, and increased apoptosis in GBM cells." | 1.39 | Inhibition of polo-like kinase 1 induces cell cycle arrest and sensitizes glioblastoma cells to ionizing radiation. ( Brassesco, MS; de Oliveira, HF; de Oliveira, JC; Morales, AG; Pezuk, JA; Scrideli, CA; Tone, LG, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, H | 1 |
| Tao, Z | 1 |
| Feng, M | 1 |
| Li, X | 1 |
| Deng, Z | 1 |
| Zhao, G | 1 |
| Yin, H | 1 |
| Pan, T | 1 |
| Chen, G | 1 |
| Feng, Z | 1 |
| Li, Y | 1 |
| Zhou, Y | 1 |
| Papa, E | 1 |
| Weller, M | 1 |
| Weiss, T | 1 |
| Ventura, E | 1 |
| Burghardt, I | 1 |
| Szabó, E | 1 |
| Pezuk, JA | 1 |
| Brassesco, MS | 1 |
| Morales, AG | 1 |
| de Oliveira, JC | 1 |
| de Oliveira, HF | 1 |
| Scrideli, CA | 1 |
| Tone, LG | 1 |
| Danovi, D | 1 |
| Folarin, A | 1 |
| Gogolok, S | 1 |
| Ender, C | 1 |
| Elbatsh, AM | 1 |
| Engström, PG | 1 |
| Stricker, SH | 1 |
| Gagrica, S | 1 |
| Georgian, A | 1 |
| Yu, D | 1 |
| U, KP | 1 |
| Harvey, KJ | 1 |
| Ferretti, P | 1 |
| Paddison, PJ | 1 |
| Preston, JE | 1 |
| Abbott, NJ | 1 |
| Bertone, P | 1 |
| Smith, A | 1 |
| Pollard, SM | 1 |
| Roffé, M | 1 |
| Lupinacci, FC | 1 |
| Soares, LC | 1 |
| Hajj, GN | 1 |
| Martins, VR | 1 |
| Lee, C | 1 |
| Fotovati, A | 1 |
| Triscott, J | 1 |
| Chen, J | 1 |
| Venugopal, C | 1 |
| Singhal, A | 1 |
| Dunham, C | 1 |
| Kerr, JM | 1 |
| Verreault, M | 1 |
| Yip, S | 1 |
| Wakimoto, H | 1 |
| Jones, C | 1 |
| Jayanthan, A | 1 |
| Narendran, A | 1 |
| Singh, SK | 1 |
| Dunn, SE | 1 |
6 other studies available for pteridines and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Dual PLK1 and STAT3 inhibition promotes glioblastoma cells apoptosis through MYC.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Carcinogenesis; Cell Cycle Proteins; Cel | 2020 |
Negative control of the HGF/c-MET pathway by TGF-β: a new look at the regulation of stemness in glioblastoma.
Topics: Antineoplastic Agents; Butadienes; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regu | 2017 |
Inhibition of polo-like kinase 1 induces cell cycle arrest and sensitizes glioblastoma cells to ionizing radiation.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Growth Processes; Cell Line, Tumor; Gli | 2013 |
A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1.
Topics: Animals; Benzimidazoles; Blood-Brain Barrier; Blotting, Western; Brain Neoplasms; Cell Cycle Checkpo | 2013 |
Two widely used RSK inhibitors, BI-D1870 and SL0101, alter mTORC1 signaling in a RSK-independent manner.
Topics: Benzopyrans; Cell Line, Tumor; Cell Proliferation; Data Mining; Dose-Response Relationship, Drug; Gl | 2015 |
Polo-like kinase 1 inhibition kills glioblastoma multiforme brain tumor cells in part through loss of SOX2 and delays tumor progression in mice.
Topics: Animals; Apoptosis; Brain Neoplasms; Cell Cycle Proteins; Cell Growth Processes; Cell Line, Tumor; D | 2012 |