Compounds > pteridines
Page last updated: 2024-10-20

pteridines and Aneuploid

pteridines has been researched along with Aneuploid in 1 studies

Research Excerpts

ExcerptRelevanceReference
"BI 2536 is a new anti-mitotic drug that targets polo-like kinase 1 (Plk1) and is currently under clinical development for cancer therapy."5.36The Plk1 inhibitor BI 2536 temporarily arrests primary cardiac fibroblasts in mitosis and generates aneuploidy in vitro. ( de Boer, RA; Lu, B; Maass, AH; Mahmud, H; Silljé, HH; van Gilst, WH; Yu, B, 2010)
"BI 2536 is a new anti-mitotic drug that targets polo-like kinase 1 (Plk1) and is currently under clinical development for cancer therapy."1.36The Plk1 inhibitor BI 2536 temporarily arrests primary cardiac fibroblasts in mitosis and generates aneuploidy in vitro. ( de Boer, RA; Lu, B; Maass, AH; Mahmud, H; Silljé, HH; van Gilst, WH; Yu, B, 2010)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lu, B1
Mahmud, H1
Maass, AH1
Yu, B1
van Gilst, WH1
de Boer, RA1
Silljé, HH1

Other Studies

1 other study available for pteridines and Aneuploid

ArticleYear
The Plk1 inhibitor BI 2536 temporarily arrests primary cardiac fibroblasts in mitosis and generates aneuploidy in vitro.
    PloS one, 2010, Sep-24, Volume: 5, Issue:9

    Topics: Aneuploidy; Animals; Cell Cycle Proteins; Cell Differentiation; Cells, Cultured; Fibroblasts; Heart;

2010