psd-502 and Hirsutism

psd-502 has been researched along with Hirsutism* in 2 studies

Trials

2 trial(s) available for psd-502 and Hirsutism

Article	Year
A double-blind placebo controlled study of a 5% lidocaine/prilocaine cream (EMLA) for topical anesthesia during thermolysis. The Journal of dermatologic surgery and oncology, 1994, Volume: 20, Issue:2 Electrolysis and thermolysis are commonly used electrosurgical methods for the permanent destruction of unwanted hair. However, patient fear of pain during treatment may interfere with or even prevent desired treatment of hirsutism on sensitive areas such as the upper lip.. This study was conducted to assess the efficacy of EMLA (Eutetic Mixture of Local Anesthetics), a 5% lidocaine/prilocaine cream, as a topically applied local anesthetic during thermolysis on the upper lip.. A double-blind placebo control study was conducted by the University of Texas Medical Branch thermolysis clinic. Thirty women with idiopathic hirsutism of the upper lip were studied. Pain was measured with a 100 mm visual analog scale (VAS).. Total paired VAS score differences comparing the placebo VAS scores to the EMLA VAS scores were significant by paired t-test (P = .0001). Adverse reactions were mild and transient.. EMLA cream may have multiple applications to the practice of dermatologic surgery, including topically achieved local anesthesia during thermolysis and electrolysis. Topics: Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Drug Combinations; Female; Hair Removal; Hirsutism; Hot Temperature; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Lip Diseases; Middle Aged; Ointments; Pain; Pain Measurement; Placebos; Prilocaine	1994
Epilation of upper lip hirsutism with a eutectic mixture of lidocaine and prilocaine used as a topical anesthetic. Journal of the American Academy of Dermatology, 1991, Volume: 25, Issue:5 Pt 1 Twenty-one patients were included in a double-blind, placebo-controlled, cross-over study with a eutectic mixture of lidocaine and prilocaine (EMLA). EMLA or placebo was placed on the upper lip for 1 hour; diathermy was then performed for 10 minutes. The pain caused by diathermy was evaluated by the patients and the cosmetologist on a four-point scale. The results of the investigation showed that there was significantly less pain after application of 5 gm of EMLA cream on the upper lip than after application of placebo, assessed both by the patient and by the cosmetologist. Eighteen of 20 patients preferred EMLA (p less than 0.0001). Local reactions were few and mild. Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Diathermy; Double-Blind Method; Drug Combinations; Female; Hair Removal; Hirsutism; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Lip; Middle Aged; Pain; Placebos; Prilocaine	1991

Article

Year

A double-blind placebo controlled study of a 5% lidocaine/prilocaine cream (EMLA) for topical anesthesia during thermolysis.

The Journal of dermatologic surgery and oncology, 1994, Volume: 20, Issue:2

Electrolysis and thermolysis are commonly used electrosurgical methods for the permanent destruction of unwanted hair. However, patient fear of pain during treatment may interfere with or even prevent desired treatment of hirsutism on sensitive areas such as the upper lip.. This study was conducted to assess the efficacy of EMLA (Eutetic Mixture of Local Anesthetics), a 5% lidocaine/prilocaine cream, as a topically applied local anesthetic during thermolysis on the upper lip.. A double-blind placebo control study was conducted by the University of Texas Medical Branch thermolysis clinic. Thirty women with idiopathic hirsutism of the upper lip were studied. Pain was measured with a 100 mm visual analog scale (VAS).. Total paired VAS score differences comparing the placebo VAS scores to the EMLA VAS scores were significant by paired t-test (P = .0001). Adverse reactions were mild and transient.. EMLA cream may have multiple applications to the practice of dermatologic surgery, including topically achieved local anesthesia during thermolysis and electrolysis.

Topics: Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Drug Combinations; Female; Hair Removal; Hirsutism; Hot Temperature; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Lip Diseases; Middle Aged; Ointments; Pain; Pain Measurement; Placebos; Prilocaine

1994

Epilation of upper lip hirsutism with a eutectic mixture of lidocaine and prilocaine used as a topical anesthetic.

Journal of the American Academy of Dermatology, 1991, Volume: 25, Issue:5 Pt 1

Twenty-one patients were included in a double-blind, placebo-controlled, cross-over study with a eutectic mixture of lidocaine and prilocaine (EMLA). EMLA or placebo was placed on the upper lip for 1 hour; diathermy was then performed for 10 minutes. The pain caused by diathermy was evaluated by the patients and the cosmetologist on a four-point scale. The results of the investigation showed that there was significantly less pain after application of 5 gm of EMLA cream on the upper lip than after application of placebo, assessed both by the patient and by the cosmetologist. Eighteen of 20 patients preferred EMLA (p less than 0.0001). Local reactions were few and mild.

Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Diathermy; Double-Blind Method; Drug Combinations; Female; Hair Removal; Hirsutism; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Lip; Middle Aged; Pain; Placebos; Prilocaine

1991