psd-502 and Hematologic-Neoplasms

To assess the analgesic efficacy of compound lidocaine cream in lumbar puncture of children with leukemia and lymphoma.. 312 leukemia and lymphoma children necessarily undergone lumbar puncture were divided into compound lidocaine cream (cream) group and compound lidocaine injection (injation) group as control with 156 cases respectively according to the will of inpatient children and their family. For cream group, compound lidocaine cream was smeared on the skin around the lumbar puncture point evenly and covered with sterile and transparent dressing for about one hour before lumbar puncture. Then the cream and transparent dressing were removed and lumbar puncture was performed after regular disinfection. For control group, 2% compound lidocaine was injected as local anesthesia before lumbar puncture. The extent of pain was evaluated by Wong-Baker Faces Pain Rating Scale and FLACC Scale as well as children's physiological indexes (heart rate, breathing, blood pressure). The lumbar puncture success rate and the discomfortableness as well as family satisfaction were recorded by special person.. Compared with control group, the incidence of pain and discomfortableness in cream group significantly reduced, and the family satisfaction significantly increased (P＜0.05). There were obviously differences in the physiological indexes (heart rate, breathing, systolic blood pressure) before and after lumbar puncture in control group (P＜0.05). However, the physiological indexes in cream group had no obvious change. There was no difference on the success rate of lumbar puncture between the two methods of anesthesia.. Compound lidocaine cream has significantly analgesic effect which can relieving pain caused by lumbar puncture for children.. 复方利多卡因乳膏在血液系统肿瘤患儿腰椎穿刺术中的镇痛效果分析.. 研究复方利多卡因乳膏在白血病和淋巴瘤患儿腰椎穿刺术中的镇痛效果。.. 选择312例住院治疗需进行腰椎穿刺的白血病和淋巴瘤患儿，结合患儿及家属意愿将其分为利多卡因乳膏（乳膏）组和利多卡因注射液（对照）组，各156例。术前在观察组患儿腰椎穿刺点周围均匀涂抹复方利多卡因乳膏，然后用无菌透明敷贴覆盖1 h，将贴膜和乳膏清理干净，消毒后行腰椎穿刺。对照组患儿采用2 %利多卡因注射液进行局部麻醉后行腰椎穿刺。患儿疼痛程度的判定参照FLACC和Wong-baker评分表，观察穿刺前后生理指标的变化，同时计算穿刺成功率，并调查穿刺后的不良反应发生率与家属满意度。.. 相较于乳膏组，观察组患儿的疼痛程度以及不良反应发生率明显降低（P＜0.05），家属满意度明显升高（P＜0.05）；对照组患儿穿刺前后的生理指标发生了明显改变（P＜0.05），而乳膏组穿刺前后的生理指标无明显变化（P＞0.05）；两种麻醉方式的穿刺成功率无显著性差异（P＞0.05）。.. 复方利多卡因乳膏在肿瘤患儿腰椎穿刺时具有显著的镇痛效果，能够有效减轻患儿的疼痛。.

Topics: Analgesics; Anesthetics, Local; Child; Hematologic Neoplasms; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Spinal Puncture