psd-502 and Eyelid-Diseases

psd-502 has been researched along with Eyelid-Diseases* in 2 studies

Trials

1 trial(s) available for psd-502 and Eyelid-Diseases

Article	Year
Effect of a topical anesthetic cream (EMLA) in reducing pain caused by infiltration of local anesthetic in eyelid surgery. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1993, Volume: 28, Issue:4 EMLA (eutectic mixture of local anesthetics) cream is a topical formulation of a mixture of lidocaine and prilocaine. It has been used to achieve local analgesia after application under an occlusive dressing. We carried out a double-blind randomized controlled clinical trial to assess the effect of 5% EMLA (25 mg/mL of lidocaine and of prilocaine) in reducing the pain caused by infiltration of local anesthetic in eyelid surgery. Pain was assessed by means of a modified visual analogue scale ranging from 0 (no pain) to 10 (excruciating pain) in 25 consecutive patients (average age 65 years) undergoing bilateral eyelid surgery. Clinical significance was defined as a difference in pain scores of 3 or more between EMLA and placebo. The mean pain scores for EMLA and placebo were 3.1 and 4.0 respectively, a nonsignificant difference. The EMLA preparation was found not to be clinically effective in reducing pain caused by infiltration of local anesthetic in eyelid surgery. Topics: Aged; Anesthetics, Local; Double-Blind Method; Drug Combinations; Eyelid Diseases; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Ointments; Pain; Pain Measurement; Prilocaine	1993

Article

Year

Effect of a topical anesthetic cream (EMLA) in reducing pain caused by infiltration of local anesthetic in eyelid surgery.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1993, Volume: 28, Issue:4

EMLA (eutectic mixture of local anesthetics) cream is a topical formulation of a mixture of lidocaine and prilocaine. It has been used to achieve local analgesia after application under an occlusive dressing. We carried out a double-blind randomized controlled clinical trial to assess the effect of 5% EMLA (25 mg/mL of lidocaine and of prilocaine) in reducing the pain caused by infiltration of local anesthetic in eyelid surgery. Pain was assessed by means of a modified visual analogue scale ranging from 0 (no pain) to 10 (excruciating pain) in 25 consecutive patients (average age 65 years) undergoing bilateral eyelid surgery. Clinical significance was defined as a difference in pain scores of 3 or more between EMLA and placebo. The mean pain scores for EMLA and placebo were 3.1 and 4.0 respectively, a nonsignificant difference. The EMLA preparation was found not to be clinically effective in reducing pain caused by infiltration of local anesthetic in eyelid surgery.

Topics: Aged; Anesthetics, Local; Double-Blind Method; Drug Combinations; Eyelid Diseases; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Ointments; Pain; Pain Measurement; Prilocaine

1993

Other Studies

1 other study(ies) available for psd-502 and Eyelid-Diseases

Article	Year
Percutaneous anaesthesia with a lignocaine-prilocaine cream (Emla) for eyelid skin surgery. The British journal of ophthalmology, 1994, Volume: 78, Issue:3 Epicutaneous application of the anaesthetic cream Emla (lignocaine and prilocaine), to induce percutaneous anaesthesia in 38 patients scheduled for eyelid skin surgery is presented. The cream was applied 60 to 90 minutes before operation. In 36 out of the 38 patients (94.8%) no supplementary analgesia was required. The pain during the procedure was rated either as no pain in 29 patients (76.3%), slight pain in five patients (13%), moderate pain in two patients (5.2%), and severe pain in two patients (5.2%). Percutaneous anaesthesia induced by Emla cream is a useful and painless alternative method for analgesia in eyelid skin surgery. Topics: Administration, Cutaneous; Adult; Aged; Anesthetics, Local; Drug Combinations; Eyelid Diseases; Eyelids; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Middle Aged; Pain Measurement; Prilocaine	1994

Article

Year

Percutaneous anaesthesia with a lignocaine-prilocaine cream (Emla) for eyelid skin surgery.

The British journal of ophthalmology, 1994, Volume: 78, Issue:3

Epicutaneous application of the anaesthetic cream Emla (lignocaine and prilocaine), to induce percutaneous anaesthesia in 38 patients scheduled for eyelid skin surgery is presented. The cream was applied 60 to 90 minutes before operation. In 36 out of the 38 patients (94.8%) no supplementary analgesia was required. The pain during the procedure was rated either as no pain in 29 patients (76.3%), slight pain in five patients (13%), moderate pain in two patients (5.2%), and severe pain in two patients (5.2%). Percutaneous anaesthesia induced by Emla cream is a useful and painless alternative method for analgesia in eyelid skin surgery.

Topics: Administration, Cutaneous; Adult; Aged; Anesthetics, Local; Drug Combinations; Eyelid Diseases; Eyelids; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Middle Aged; Pain Measurement; Prilocaine

1994