psd-502 and Coma

A 2-year-old girl lost consciousness after the topical application of lidocaine-prilocaine cream (EMLA) in preparation for the removal of multiple mollusca contagiosa. Both the area on which cream was applied (80% of body surface) and the total amount of cream (90 g) exceeded the maximum dosage. Lidocaine-prilocaine cream is a widely used local anaesthetic with few side effects when used properly. Intoxication with a lidocaine-prilocaine preparation may have serious consequences, such as changes in intracardiac conduction, excitation or depression of the central nervous system and methaemoglobinaemia. In our patient both methaemoglobinaemia and depression of the central nervous system occurred, resulting in loss of consciousness. She was treated with 100% oxygen and fully recovered.

Topics: Anesthetics, Local; Child, Preschool; Coma; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Molluscum Contagiosum; Ointments; Oxygen; Prilocaine; Treatment Outcome

Topics: Anesthetics, Combined; Anesthetics, Local; Coma; Communication; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Medical Errors; Prilocaine

Topics: Anesthetics, Local; Coma; Diagnosis, Differential; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Prilocaine

Topics: Anesthetics, Local; Clinical Protocols; Coma; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Molluscum Contagiosum; Ointments; Prilocaine