proxymetacaine has been researched along with Retinopathy of Prematurity in 13 studies
proxymetacaine: RN given refers to parent cpd; structure
Retinopathy of Prematurity: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine whether the addition of sucrose 24% to topical anesthetic improves procedural pain control during the ROP eye examination." | 9.11 | Efficacy of sucrose to reduce pain in premature infants during eye examinations for retinopathy of prematurity. ( Carlos, RQ; Dunaway, KK; Gal, P; Jones, SM; Kissling, GE; Marsh, VA; Ransom, JL; Shockley, DH; Weaver, NL; Young, WO, 2005) |
| "To examine whether the addition of sucrose 24% to topical anesthetic improves procedural pain control during the ROP eye examination." | 5.11 | Efficacy of sucrose to reduce pain in premature infants during eye examinations for retinopathy of prematurity. ( Carlos, RQ; Dunaway, KK; Gal, P; Jones, SM; Kissling, GE; Marsh, VA; Ransom, JL; Shockley, DH; Weaver, NL; Young, WO, 2005) |
| "Sucrose reduced pain during the eye examination, whereas the efficacy of proparacaine was not consistent in the studies included." | 4.86 | Pain management during eye examinations for retinopathy of prematurity in preterm infants: a systematic review. ( Barrowman, N; Lemyre, B; O'Connor, M; Sun, X, 2010) |
| "Pain was assessed by PIPP scale, during and at 1 and 5 min after the procedure by the principal investigator who was blinded." | 2.80 | Efficacy of expressed breast milk in reducing pain during ROP screening--a randomized controlled trial. ( Bhat, S; Mathew, S; Nesargi, S; Rao, SP; Rosali, L; Vasu, U, 2015) |
| "Pain was measured using a scoring system with both physical and physiologic measures of pain (Premature Infant Pain Profile [PIPP], possible range 1-21), which has been validated in preterm infants." | 2.71 | Efficacy of topical anesthetics to reduce pain in premature infants during eye examinations for retinopathy of prematurity. ( Carlos, RQ; Dunaway, KK; Gal, P; Jones, SM; Kissling, GE; Marsh, VA; Ransom, JL; Shockley, DH; Weaver, NL; Young, WO, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 9 (69.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nesargi, SV | 1 |
| Nithyanandam, S | 1 |
| Rao, S | 1 |
| Nimbalkar, S | 1 |
| Bhat, S | 2 |
| Rosali, L | 1 |
| Nesargi, S | 1 |
| Mathew, S | 1 |
| Vasu, U | 1 |
| Rao, SP | 1 |
| Kabataş, EU | 1 |
| Dursun, A | 1 |
| Beken, S | 1 |
| Dilli, D | 1 |
| Zenciroğlu, A | 1 |
| Okumuş, N | 1 |
| Ahmed, M | 1 |
| Forcina, B | 1 |
| Bonsall, D | 1 |
| Sun, X | 1 |
| Lemyre, B | 1 |
| Barrowman, N | 1 |
| O'Connor, M | 1 |
| Mehta, M | 1 |
| Mansfield, T | 1 |
| VanderVeen, DK | 1 |
| Cogen, MS | 1 |
| Parker, JS | 1 |
| Sleep, TE | 1 |
| Elsas, FJ | 1 |
| Metz, TH | 1 |
| McGwin, G | 1 |
| Kandasamy, Y | 1 |
| Smith, R | 1 |
| Wright, IM | 1 |
| Hartley, L | 1 |
| Dempsey, E | 1 |
| McCreery, K | 1 |
| Rush, R | 1 |
| Rush, S | 1 |
| Nicolau, J | 1 |
| Chapman, K | 1 |
| Naqvi, M | 1 |
| Marsh, VA | 2 |
| Young, WO | 2 |
| Dunaway, KK | 2 |
| Kissling, GE | 2 |
| Carlos, RQ | 2 |
| Jones, SM | 2 |
| Shockley, DH | 2 |
| Weaver, NL | 2 |
| Ransom, JL | 2 |
| Gal, P | 2 |
| Saunders, RA | 1 |
| Miller, KW | 1 |
| Hunt, HH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intranasal Dexmedetomidine for Pain Management During Screening for Retinopathy of Prematurity: A Crossover Randomized Controlled Trial[NCT06067958] | Phase 3 | 30 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
| Efficiency and Safety of Phenylephrine and Tropicamide Used in Premature Retinopathy[NCT03448640] | 60 participants (Actual) | Observational | 2016-01-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for proxymetacaine and Retinopathy of Prematurity
| Article | Year |
|---|---|
Pain management during eye examinations for retinopathy of prematurity in preterm infants: a systematic review.
Topics: Administration, Topical; Anesthetics, Local; Humans; Infant, Newborn; Infant, Premature; Pain; Pain | 2010 |
Pain relief for premature infants during ophthalmology assessment.
Topics: Anesthesia, Local; Anesthetics, Local; Diagnostic Techniques, Ophthalmological; Eye Pain; Humans; In | 2011 |
Local anaesthetic eye drops for prevention of pain in preterm infants undergoing screening for retinopathy of prematurity.
Topics: Anesthetics, Local; Eye Pain; Humans; Infant, Extremely Low Birth Weight; Infant, Newborn; Infant, P | 2011 |
8 trials available for proxymetacaine and Retinopathy of Prematurity
| Article | Year |
|---|---|
Topical anesthesia or oral dextrose for the relief of pain in screening for retinopathy of prematurity: a randomized controlled double-blinded trial.
Topics: Administration, Oral; Administration, Topical; Anesthetics, Local; Double-Blind Method; Eye Pain; Gl | 2015 |
Efficacy of expressed breast milk in reducing pain during ROP screening--a randomized controlled trial.
Topics: Anesthetics, Local; Breast Feeding; Double-Blind Method; Female; Humans; Infant, Newborn; Male; Mass | 2015 |
Efficacy of Single Dose Oral Paracetamol in Reducing Pain During Examination for Retinopathy of Prematurity: A Blinded Randomized Controlled Trial.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anesthetics, Local; Crying; Double-Bl | 2016 |
Effect of topical anesthesia and age on pain scores during retinopathy of prematurity screening.
Topics: Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Gestational Age; Humans; Infant, Newbor | 2010 |
Masked trial of topical anesthesia for retinopathy of prematurity eye examinations.
Topics: Administration, Topical; Anesthetics, Local; Double-Blind Method; Gestational Age; Humans; Infant, N | 2011 |
Efficacy of topical anesthetics to reduce pain in premature infants during eye examinations for retinopathy of prematurity.
Topics: Administration, Topical; Anesthetics, Local; Cross-Over Studies; Diagnostic Techniques, Ophthalmolog | 2005 |
Efficacy of sucrose to reduce pain in premature infants during eye examinations for retinopathy of prematurity.
Topics: Administration, Oral; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Drug Therapy, Com | 2005 |
Topical anesthesia during infant eye examinations: does it reduce stress?
Topics: Administration, Topical; Anesthesia, Local; Cornea; Double-Blind Method; Female; Hemodynamics; Human | 1993 |
2 other studies available for proxymetacaine and Retinopathy of Prematurity
| Article | Year |
|---|---|
Quantifying and qualifying the use of topical anesthetics in retinopathy of prematurity examinations.
Topics: Administration, Topical; Anesthetics, Local; Gestational Age; Guidelines as Topic; Health Care Surve | 2016 |
Systemic manifestations in response to mydriasis and physical examination during screening for retinopathy of prematurity.
Topics: Administration, Topical; Anesthetics, Local; Drug Administration Schedule; Eyelids; Humans; Infant, | 2004 |