Page last updated: 2024-11-03

proxymetacaine and Pain

proxymetacaine has been researched along with Pain in 24 studies

proxymetacaine: RN given refers to parent cpd; structure

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"To examine whether the addition of sucrose 24% to topical anesthetic improves procedural pain control during the ROP eye examination."9.11Efficacy of sucrose to reduce pain in premature infants during eye examinations for retinopathy of prematurity. ( Carlos, RQ; Dunaway, KK; Gal, P; Jones, SM; Kissling, GE; Marsh, VA; Ransom, JL; Shockley, DH; Weaver, NL; Young, WO, 2005)
"Sixty patients receiving intravitreal injections over 15 months for macular edema because of diabetes, age-related macular degeneration, or retinal vein occlusion who were randomized into 3 groups to receive 1 of 3 commonly used forms of anesthesia-TetraVisc, proparacaine HCl, or tetracaine HCl-before receiving intravitreal injection were studied."5.16Factors affecting patients' pain intensity during in office intravitreal injection procedure. ( Rifkin, L; Schaal, S, 2012)
"To examine whether the addition of sucrose 24% to topical anesthetic improves procedural pain control during the ROP eye examination."5.11Efficacy of sucrose to reduce pain in premature infants during eye examinations for retinopathy of prematurity. ( Carlos, RQ; Dunaway, KK; Gal, P; Jones, SM; Kissling, GE; Marsh, VA; Ransom, JL; Shockley, DH; Weaver, NL; Young, WO, 2005)
"Sucrose reduced pain during the eye examination, whereas the efficacy of proparacaine was not consistent in the studies included."4.86Pain management during eye examinations for retinopathy of prematurity in preterm infants: a systematic review. ( Barrowman, N; Lemyre, B; O'Connor, M; Sun, X, 2010)
"Narcotics and topical diclofenac were used to control pain in a patient who developed a corneal ulcer after abusing topical anesthetics."3.70Topical diclofenac sodium in the management of anesthetic abuse keratopathy. ( Dornic, DI; Lass, JH; Thomas, JM, 1998)
"We studied 66 consecutive patients (73 afflicted eyes) who presented to a university hospital emergency department with the complaint of eye pain."3.69Visual acuity after topical application of proparacaine. ( Berndt, D; Bossart, PJ; Herr, RD; Stephen, RL, 1997)
"Pain was assessed by PIPP scale, during and at 1 and 5 min after the procedure by the principal investigator who was blinded."2.80Efficacy of expressed breast milk in reducing pain during ROP screening--a randomized controlled trial. ( Bhat, S; Mathew, S; Nesargi, S; Rao, SP; Rosali, L; Vasu, U, 2015)
"Pain was measured using a scoring system with both physical and physiologic measures of pain (Premature Infant Pain Profile [PIPP], possible range 1-21), which has been validated in preterm infants."2.71Efficacy of topical anesthetics to reduce pain in premature infants during eye examinations for retinopathy of prematurity. ( Carlos, RQ; Dunaway, KK; Gal, P; Jones, SM; Kissling, GE; Marsh, VA; Ransom, JL; Shockley, DH; Weaver, NL; Young, WO, 2005)
" After rats were injected intrathecally with proxymetacaine, oxybuprocaine, bupivacaine, and lidocane, dose-response curves were constructed."1.35Intrathecal oxybuprocaine and proxymetacaine produced potent and long-lasting spinal anesthesia in rats. ( Chen, YC; Chen, YW; Chu, CC; Hung, CH; Wang, JJ, 2009)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.33)18.7374
1990's4 (16.67)18.2507
2000's10 (41.67)29.6817
2010's8 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rosali, L1
Nesargi, S1
Mathew, S1
Vasu, U1
Rao, SP1
Bhat, S1
Kabataş, EU1
Dursun, A1
Beken, S1
Dilli, D1
Zenciroğlu, A1
Okumuş, N1
Hung, CH1
Wang, JJ1
Chen, YC1
Chu, CC1
Chen, YW1
Sun, X1
Lemyre, B1
Barrowman, N1
O'Connor, M1
Ioannidis, AS1
Papageorgiou, K1
Alexandraki, KI1
Massaoutis, P1
Sinha, AJ1
Andreou, PS1
Mehta, M1
Mansfield, T1
VanderVeen, DK1
Cogen, MS1
Parker, JS1
Sleep, TE1
Elsas, FJ1
Metz, TH1
McGwin, G1
Yagci, A1
Bozkurt, B1
Egrilmez, S1
Palamar, M1
Ozturk, BT1
Pekel, H1
Rifkin, L1
Schaal, S1
Mathew, MR1
Webb, LA1
Hill, R1
BOOZAN, CW1
COHEN, IJ1
Habib, NE1
Mandour, NM1
Balmer, HG1
Marsh, VA2
Young, WO2
Dunaway, KK2
Kissling, GE2
Carlos, RQ2
Jones, SM2
Shockley, DH2
Weaver, NL2
Ransom, JL2
Gal, P2
O'Brien, PD1
Fitzpatrick, P1
Power, W1
Kiliç, A1
Gürler, B1
Friberg, TR1
Venkatesh, S1
Bossart, PJ1
Stephen, RL1
Herr, RD1
Berndt, D1
Dornic, DI1
Thomas, JM1
Lass, JH1
Shafi, T1
Koay, P1
Zollman, TM1
Bragg, RM1
Harrison, DA1
Sutherland, MS1
Young, JD1
Birchall, W1
Kumar, V1
Sklar, DP1
Lauth, JE1
Johnson, DR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intranasal Dexmedetomidine for Pain Management During Screening for Retinopathy of Prematurity: A Crossover Randomized Controlled Trial[NCT06067958]Phase 330 participants (Anticipated)Interventional2024-01-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for proxymetacaine and Pain

ArticleYear
Pain management during eye examinations for retinopathy of prematurity in preterm infants: a systematic review.
    Acta paediatrica (Oslo, Norway : 1992), 2010, Volume: 99, Issue:3

    Topics: Administration, Topical; Anesthetics, Local; Humans; Infant, Newborn; Infant, Premature; Pain; Pain

2010

Trials

14 trials available for proxymetacaine and Pain

ArticleYear
Efficacy of expressed breast milk in reducing pain during ROP screening--a randomized controlled trial.
    Journal of tropical pediatrics, 2015, Volume: 61, Issue:2

    Topics: Anesthetics, Local; Breast Feeding; Double-Blind Method; Female; Humans; Infant, Newborn; Male; Mass

2015
Efficacy of Single Dose Oral Paracetamol in Reducing Pain During Examination for Retinopathy of Prematurity: A Blinded Randomized Controlled Trial.
    Indian journal of pediatrics, 2016, Volume: 83, Issue:1

    Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anesthetics, Local; Crying; Double-Bl

2016
Light sensitivity and pain sensation during cataract surgery. A comparative study of two modes of anaesthesia.
    International ophthalmology, 2010, Volume: 30, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Cataract Extraction; Dose-Response Relationship,

2010
Effect of topical anesthesia and age on pain scores during retinopathy of prematurity screening.
    Journal of perinatology : official journal of the California Perinatal Association, 2010, Volume: 30, Issue:11

    Topics: Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Gestational Age; Humans; Infant, Newbor

2010
Masked trial of topical anesthesia for retinopathy of prematurity eye examinations.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2011, Volume: 15, Issue:1

    Topics: Administration, Topical; Anesthetics, Local; Double-Blind Method; Gestational Age; Humans; Infant, N

2011
Factors affecting patients' pain intensity during in office intravitreal injection procedure.
    Retina (Philadelphia, Pa.), 2012, Volume: 32, Issue:4

    Topics: Aged; Analysis of Variance; Anesthesia; Anesthetics, Local; Diabetic Retinopathy; Female; Humans; In

2012
Effect of midazolam on anxiety level and pain perception in cataract surgery with topical anesthesia.
    Journal of cataract and refractive surgery, 2004, Volume: 30, Issue:2

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Intravenous; Anesthetics, Local; Anxiety; D

2004
Efficacy of topical anesthetics to reduce pain in premature infants during eye examinations for retinopathy of prematurity.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:5

    Topics: Administration, Topical; Anesthetics, Local; Cross-Over Studies; Diagnostic Techniques, Ophthalmolog

2005
Efficacy of sucrose to reduce pain in premature infants during eye examinations for retinopathy of prematurity.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:6

    Topics: Administration, Oral; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Drug Therapy, Com

2005
Subtenon lidocaine vs topical proparacaine in adult strabismus surgery.
    Annals of ophthalmology (Skokie, Ill.), 2006,Fall, Volume: 38, Issue:3

    Topics: Administration, Topical; Adult; Anesthetics, Local; Eye; Humans; Injections; Intraoperative Period;

2006
Randomised prospective masked study comparing patient comfort following the instillation of topical proxymetacaine and amethocaine.
    The British journal of ophthalmology, 1998, Volume: 82, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Female; Humans;

1998
Clinical effects of oleoresin capsicum (pepper spray) on the human cornea and conjunctiva.
    Ophthalmology, 2000, Volume: 107, Issue:12

    Topics: Adult; Analgesics; Anesthetics, Local; Conjunctiva; Cornea; Female; Flurbiprofen; Humans; Male; Midd

2000
Does instilling proxymetacaine before cyclopentolate significantly reduce stinging? The implications of paediatric cycloplegia.
    The British journal of ophthalmology, 2001, Volume: 85, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Cyclopentolate; Double-Blind Method; Humans; Iso

2001
A comparative study of proxymetacaine-fluorescein and lignocaine-fluorescein use during applanation tonometry.
    The British journal of ophthalmology, 2001, Volume: 85, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Coloring Agents; Double-Blind Method; Female; Fl

2001

Other Studies

9 other studies available for proxymetacaine and Pain

ArticleYear
Intrathecal oxybuprocaine and proxymetacaine produced potent and long-lasting spinal anesthesia in rats.
    Neuroscience letters, 2009, May-01, Volume: 454, Issue:3

    Topics: Anesthesia, Spinal; Anesthetics, Local; Animals; Dose-Response Relationship, Drug; Injections, Spina

2009
Topical anesthetic abuse keratopathy: a commonly overlooked health care problem.
    Cornea, 2011, Volume: 30, Issue:5

    Topics: Administration, Topical; Adult; Anesthetics, Local; Anti-Bacterial Agents; Corneal Ulcer; Epithelium

2011
Surgeon experience and patient comfort during clear corneal phacoemulsification under topical local anesthesia.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:11

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Clinical Competence; Cornea; Female;

2002
Ophthaine, a new topical anesthetic for the eye.
    American journal of ophthalmology, 1953, Volume: 36, Issue:11

    Topics: Aminobenzoates; Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthetics, Local; Eye; Liver Cirr

1953
Patient pain during stretching of small pupils in phacoemulsification performed using topical anesthesia.
    Journal of cataract and refractive surgery, 2005, Volume: 31, Issue:9

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Female; Humans; Iris; Male; Pain; Pa

2005
Alteration of pulse configuration affects the pain response during diode laser photocoagulation.
    Lasers in surgery and medicine, 1995, Volume: 16, Issue:4

    Topics: Analysis of Variance; Anesthesia, Local; Anesthetics, Local; Diabetic Retinopathy; Electronics, Medi

1995
Visual acuity after topical application of proparacaine.
    Annals of emergency medicine, 1997, Volume: 29, Issue:1

    Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthetics, Local; Child; Eye; Female; Humans; Ma

1997
Topical diclofenac sodium in the management of anesthetic abuse keratopathy.
    American journal of ophthalmology, 1998, Volume: 125, Issue:5

    Topics: Administration, Topical; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Corneal

1998
Topical anesthesia of the eye as a diagnostic test.
    Annals of emergency medicine, 1989, Volume: 18, Issue:11

    Topics: Acute Disease; Anesthesia, Local; Anesthetics, Local; Corneal Injuries; Diagnosis, Differential; Eme

1989